Bruce J MacLachlan

Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 10

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Discovery immunology

The Journal of biological chemistry

Cancer immunology, immunotherapy : CII

Monash University

Cardiff University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Monash University Jul 31 2018

Australia

Postdoctoral Research Fellow :: Monash Biomedicine Discovery Institute

Cardiff University Oct 01 2016

United Kingdom

Research Associate :: Division of Infection & Immunity, School of Medicine

Education History

Cardiff University Oct 01 2012 - Sep 30 2016

United Kingdom

PHD :: Division of Infection & Immunity, School of Medicine

Imperial College London

United Kingdom

BSC :: Biochemistry

Publications

Phillip Pymm, Philippa M Saunders, Sushma Anand, Bruce J MacLachlan, Camilla Faoro, Corinne Hitchen, Jamie Rossjohn, Andrew G Brooks, Julian P Vivian
The Structural Basis for Recognition of Human Leukocyte Antigen Class I Molecules by the Pan-HLA Antibody W6/32. Journal of immunology (Baltimore, Md. : 1950) (2024)
Jade R Hopkins, Bruce J MacLachlan, Stephen Harper, Andrew K Sewell, David K Cole
Unconventional modes of peptide-HLA-I presentation change the rules of TCR engagement. Discovery immunology 1 (1) (2022)
Jade R Hopkins, Bruce J MacLachlan, Stephen Harper, Andrew K Sewell, David K Cole
Unconventional modes of peptide-HLA-I presentation change the rules of TCR engagement. Discovery immunology 1 (1) (2022)
Stephanie E A Burnell, Lorenzo Capitani, Bruce J MacLachlan, Georgina H Mason, Awen M Gallimore, Andrew Godkin
Seven mysteries of LAG-3: a multi-faceted immune receptor of increasing complexity. Immunotherapy advances 2 (1) (2021)
Shoeib Moradi, Sanda Stankovic, Geraldine M O'Connor, Phillip Pymm, Bruce J MacLachlan, Camilla Faoro, Christelle Retière, Lucy C Sullivan, Philippa M Saunders, Jacqueline M L Widjaja, Shea Cox-Livingstone, Jamie Rossjohn, Andrew G Brooks, Julian P Vivian
Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C. Nature communications 12 (1) (2021)
Philippa M Saunders, Bruce J MacLachlan, Jacqueline M L Widjaja, Shu Cheng Wong, Clare V L Oates, Jamie Rossjohn, Julian P Vivian, Andrew G Brooks
The Role of the HLA Class I α2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1. Journal of immunology (Baltimore, Md. : 1950) 206 (4) (2021)
Bruce J MacLachlan, Georgina H Mason, Alexander Greenshields-Watson, Frederic Triebel, Awen Gallimore, David K Cole, Andrew Godkin
Molecular characterization of HLA class II binding to the LAG-3 T cell co-inhibitory receptor. European journal of immunology 51 (2) (2020)
Philippa M Saunders, Bruce J MacLachlan, Phillip Pymm, Patricia T Illing, Yuanchen Deng, Shu Cheng Wong, Clare V L Oates, Anthony Wayne Purcell, Jamie Rossjohn, Julian P Vivian, Andrew G Brooks
The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proceedings of the National Academy of Sciences of the United States of America 117 (21) (2020)
Bruce J MacLachlan, Garry Dolton, Athanasios Papakyriakou, Alexander Greenshields-Watson, Georgina H Mason, Andrea Schauenburg, Matthieu Besneux, Barbara Szomolay, Tim Elliott, Andrew K Sewell, Awen M Gallimore, Pierre J Rizkallah, David K Cole, Andrew Godkin
Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. The Journal of biological chemistry 294 (52) (2019)
Matthieu Besneux, Alexander Greenshields-Watson, Martin J Scurr, Bruce J MacLachlan, Adam Christian, Michael M Davies, Rachel Hargest, Simon Phillips, Andrew Godkin, Awen M Gallimore
The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design. Cancer immunology, immunotherapy : CII 68 (2) (2018)

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Publication Activity (10 Years)

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Bruce J MacLachlan