Andrew K Sewell (Andrew Sewell)

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 19

Top Venues

Nature communications

Journal of immunology (Baltimore, Md. : 1950)

The Journal of biological chemistry

PLoS pathogens

Cardiff University

University of Liverpool (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Cardiff University Jan 01 2014

United Kingdom

Wellcome Trust Senior Investigator :: Division of Infection and Immunity

Cardiff University Jul 01 2006

United Kingdom

Distinguished Research Professor :: Schools of Medicine

University of Oxford Mar 01 2004 - Jun 30 2008

United Kingdom

Research Lecturer :: Medicine

Cardiff University Jul 01 2006 - Dec 31 2007

United Kingdom

Wellcome Trust Senior Fellow :: School of Medicine

University of Oxford Jan 01 2001 - Jun 01 2006

United Kingdom

Wellcome Trust Senior Fellow :: Medicine

University of Utah Mar 01 1991 - Feb 28 2004

United States

Postdoctoral Fellow :: Medicine

University of Oxford Jun 01 1995 - Dec 31 2000

United Kingdom

Wellcome Trust Postdoctoral Fellow :: Nuffield Department of Medicine

University of Utah Mar 01 1994 - May 31 1995

United States

Research Assistant Professor :: Medicine

Education History

University of Liverpool Oct 01 1987 - Mar 31 1991

United Kingdom

PHD :: Genetics & Botany

Publications

Mathieu Ferrari, Matteo Righi, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Alexander Kinna, Biao Ma, Reyisa Bughda, Zulaikha Akbar, Saket Srivastava, Isaac Gannon, Mathew Robson, James E Sillibourne, Ram Jha, Mohamed El-Kholy, Oliver Muhammad Amin, Evangelia Kokalaki, Mohammed Amin Banani, Rehan Hussain, William Day, Wen Chean Lim, Priyanka Ghongane, Jade R Hopkins, Dennis Jungherz, Marco Herling, Martin Welin, Sachin Surade, Michael R Dyson, John McCafferty, Derek Logan, Shaun Cordoba, Simon Thomas, Andrew K Sewell, Paul M Maciocia, Shimobi Onuoha, Martin A Pule
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies. Nature communications 15 (1) (2024)
Mathieu Ferrari, Matteo Righi, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Alexander Kinna, Biao Ma, Reyisa Bughda, Zulaikha Akbar, Saket Srivastava, Isaac Gannon, Mathew Robson, James E Sillibourne, Ram Jha, Mohamed El-Kholy, Oliver Muhammad Amin, Evangelia Kokalaki, Mohammed Amin Banani, Rehan Hussain, William Day, Wen Chean Lim, Priyanka Ghongane, Jade R Hopkins, Dennis Jungherz, Marco Herling, Martin Welin, Sachin Surade, Michael R Dyson, John McCafferty, Derek Logan, Shaun Cordoba, Simon Thomas, Andrew K Sewell, Paul M Maciocia, Shimobi Onuoha, Martin A Pule
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies. Nature communications 15 (1) (2024)
Mathieu Ferrari, Matteo Righi, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Alexander Kinna, Biao Ma, Reyisa Bughda, Zulaikha Akbar, Saket Srivastava, Isaac Gannon, Mathew Robson, James E Sillibourne, Ram Jha, Mohamed El-Kholy, Oliver Muhammad Amin, Evangelia Kokalaki, Mohammed Amin Banani, Rehan Hussain, William Day, Wen Chean Lim, Priyanka Ghongane, Jade R Hopkins, Dennis Jungherz, Marco Herling, Martin Welin, Sachin Surade, Michael R Dyson, John McCafferty, Derek Logan, Shaun Cordoba, Simon Thomas, Andrew K Sewell, Paul M Maciocia, Shimobi Onuoha, Martin A Pule
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies. Nature communications 15 (1) (2024)
Mathieu Ferrari, Matteo Righi, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Alexander Kinna, Biao Ma, Reyisa Bughda, Zulaikha Akbar, Saket Srivastava, Isaac Gannon, Mathew Robson, James E Sillibourne, Ram Jha, Mohamed El-Kholy, Oliver Muhammad Amin, Evangelia Kokalaki, Mohammed Amin Banani, Rehan Hussain, William Day, Wen Chean Lim, Priyanka Ghongane, Jade R Hopkins, Dennis Jungherz, Marco Herling, Martin Welin, Sachin Surade, Michael R Dyson, John McCafferty, Derek Logan, Shaun Cordoba, Simon Thomas, Andrew K Sewell, Paul M Maciocia, Shimobi Onuoha, Martin A Pule
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies. Nature communications 15 (1) (2024)
Mikhail Goncharov, Dmitry Bagaev, Dmitrii Shcherbinin, Ivan V Zvyagin, Dmitriy A Bolotin, Paul Glyndwr Thomas, Anastasia A Minervina, Mikhail V Pogorelyy, Kristin Ladell, James E McLaren, David A Price, Thi H O Nguyen, Louise C Rowntree, E Bridie Clemens, Katherine Kedzierska, Garry Dolton, Cristina Rafael Rius, Andrew K Sewell, Jerome Samir, Fabio Luciani, Ksenia V Zornikova, Alexandra A Khmelevskaya, Saveliy A Sheetikov, Grigory A Efimov, Dmitriy M Chudakov, Mikhail Shugay
VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2. Nature methods 19 (9) (2022)
Mathew Clement, Lea Knezevic, Tamsin Dockree, James E McLaren, Kristin Ladell, Kelly L Miners, Sian Llewellyn-Lacey, Anzelika Rubina, Ore Francis, David K Cole, Andrew K Sewell, John S Bridgeman, David A Price, Hugo A van den Berg, Linda Wooldridge
CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor. Proceedings of the National Academy of Sciences of the United States of America 118 (29) (2021)
Jade R Hopkins, Rory M Crean, Dragana A M Catici, Andrew K Sewell, Vickery L Arcus, Marc W Van der Kamp, David K Cole, Christopher R Pudney
Peptide cargo tunes a network of correlated motions in human leucocyte antigens. The FEBS journal 287 (17) (2020)
Veronica Martini, Basudev Paudyal, Tiphany Chrun, Adam McNee, Matthew Edmans, Emmanuel Atangana Maze, Beckie Clark, Alejandro Nunez, Garry Dolton, Andrew K Sewell, Peter Beverley, Ronan MacLoughlin, Alain R Townsend, Elma Tchilian
Simultaneous Aerosol and Intramuscular Immunization with Influenza Vaccine Induces Powerful Protective Local T Cell and Systemic Antibody Immune Responses in Pigs. Journal of immunology (Baltimore, Md. : 1950) 206 (3) (2020)
Marion Tarbe, John J Miles, Emily S J Edwards, Kim M Miles, Andrew K Sewell, Brian M Baker, Stéphane Quideau
Synthesis and Biological Evaluation of Hapten-Clicked Analogues of The Antigenic Peptide Melan-A/MART-126(27L)-35. ChemMedChem 15 (9) (2020)
Michael D Crowther, Garry Dolton, Mateusz Legut, Marine E Caillaud, Angharad Lloyd, Meriem Attaf, Sarah A E Galloway, Cristina Rius, Colin P Farrell, Barbara Szomolay, Ann Ager, Alan L Parker, Anna Fuller, Marco Donia, James McCluskey, Jamie Rossjohn, Inge Marie Svane, John D Phillips, Andrew K Sewell
Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature immunology 21 (2) (2020)
Aeryon Kim, Chia-Jung Han, Ian Driver, Aleksandra K Olow, Andrew K Sewell, Zemin Zhang, Wenjun Ouyang, Jackson G Egen, Xin Yu
LILRB1 Blockade Enhances Bispecific T Cell Engager Antibody-Induced Tumor Cell Killing by Effector CD8+ T Cells. Journal of immunology (Baltimore, Md. : 1950) 203 (4) (2019)
Bruce J MacLachlan, Garry Dolton, Athanasios Papakyriakou, Alexander Greenshields-Watson, Georgina H Mason, Andrea Schauenburg, Matthieu Besneux, Barbara Szomolay, Tim Elliott, Andrew K Sewell, Awen M Gallimore, Pierre J Rizkallah, David K Cole, Andrew Godkin
Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. The Journal of biological chemistry 294 (52) (2019)
Florian Madura, Pierre J Rizkallah, Mateusz Legut, Christopher J Holland, Anna Fuller, Anna Bulek, Andrea J Schauenburg, Andrew Trimby, Jade R Hopkins, Stephen A Wells, Andrew Godkin, John J Miles, Malkit Sami, Yi Li, Nathaniel Liddy, Bent K Jakobsen, E Joel Loveridge, David K Cole, Andrew K Sewell
TCR-induced alteration of primary MHC peptide anchor residue. European journal of immunology 49 (7) (2019)
Cristina Rius, Meriem Attaf, Katie Tungatt, Valentina Bianchi, Mateusz Legut, Amandine Bovay, Marco Donia, Per Thor Straten, Mark Peakman, Inge Marie Svane, Sascha Ott, Thomas Richard Connor, Barbara Szomolay, Garry Dolton, Andrew K Sewell
Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations. Journal of immunology (Baltimore, Md. : 1950) 200 (7) (2018)
Katie Tungatt, Garry Dolton, Sophie B Morgan, Meriem Attaf, Anna Fuller, Thomas Whalley, Johanneke D Hemmink, Emily Porter, Barbara Szomolay, María Montoya, John A Hammond, John J Miles, David K Cole, Alain Townsend, Mick Bailey, Pierre J Rizkallah, Bryan Charleston, Elma Tchilian, Andrew K Sewell
Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. PLoS pathogens 14 (5) (2018)
Xiang Zhao, Shvetha Sankaran, Jiawei Yap, Chien Tei Too, Zi Zong Ho, Garry Dolton, Mateusz Legut, Ee Chee Ren, Andrew K Sewell, Antonio Bertoletti, Paul A MacAry, Joanna Brzostek, Nicholas R J Gascoigne
Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling. Nature communications 9 (1) (2018)
Paul M Maciocia, Patrycja A Wawrzyniecka, Brian Philip, Ida Ricciardelli, Ayse U Akarca, Shimobi C Onuoha, Mateusz Legut, David K Cole, Andrew K Sewell, Giuseppe Gritti, Joan Somja, Miguel A Piris, Karl S Peggs, David C Linch, Teresa Marafioti, Martin A Pule
Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies. Nature medicine 23 (12) (2017)
Mateusz Legut, Garry Dolton, Afsar Ali Mian, Oliver Gerhard Ottmann, Andrew K Sewell
CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells. Blood 131 (3) (2017)
Bruno Laugel, Angharad Lloyd, Erin W Meermeier, Michael D Crowther, Thomas R Connor, Garry Dolton, John J Miles, Scott R Burrows, Marielle C Gold, David M Lewinsohn, Andrew K Sewell
Engineering of Isogenic Cells Deficient for MR1 with a CRISPR/Cas9 Lentiviral System: Tools To Study Microbial Antigen Processing and Presentation to Human MR1-Restricted T Cells. Journal of immunology (Baltimore, Md. : 1950) 197 (3) (2016)

Andrew K Sewell.css-eqlu8i{font-size:small;padding-left:4px;} (Andrew Sewell)

Publication Activity (10 Years)

Top Topics

Top Venues

Andrew K Sewell (Andrew Sewell)