Christoph Spiess

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 20

Top Topics

Mass Spectrometry

Risk Assessment

Top Venues

Analytical chemistry

Molecular cancer therapeutics

This page only lists publications with an associated author ORCID identifier.

Publications

Stéphanie G I Polderdijk, Jazeel F Limzerwala, Christoph Spiess
Plasma membrane damage limits cytoplasmic delivery by conventional cell penetrating peptides. PloS one 19 (9) (2024)
Stéphanie G I Polderdijk, Jazeel F Limzerwala, Christoph Spiess
Plasma membrane damage limits cytoplasmic delivery by conventional cell penetrating peptides. PloS one 19 (9) (2024)
Wen-Ting K Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui T Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J Carter
Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG 1 antibodies. mAbs 16 (1) (2024)
Wen-Ting K Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui T Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J Carter
Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG 1 antibodies. mAbs 16 (1) (2024)
Stéphanie G I Polderdijk, Jazeel F Limzerwala, Christoph Spiess
Plasma membrane damage limits cytoplasmic delivery by conventional cell penetrating peptides. PloS one 19 (9) (2024)
Wen-Ting K Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui T Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J Carter
Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG 1 antibodies. mAbs 16 (1) (2024)
Rickvinder Besla, Elicia Penuel, Geoffrey Del Rosario, Ely Cosino, Szymon Myrta, Michael Dillon, Greg A Lazar, Dorothee Nickles, Christoph Spiess, Shang-Fan Yu, Andrew G Polson
T cell-Dependent Bispecific Therapy Enhances Innate Immune Activation and Antibody-Mediated Killing. Cancer immunology research (2023)
Phillip Y Chu, Hui Wang, Emily Ross, Nicole Stephens, Hui-Min Zhang, Nisana Andersen, Wayman Chan, Vittal Shivva, Susan R Crowell, Christoph Spiess, Patrick G Holder, Nicholas J Agard, Chengjie Ji, John Chen, Alavattam Sreedhara, Jianyong Wang, Cong Wu, Yichin Liu, John C Tran
Translatability of In Vitro Stress for Predicting Deamidation and Oxidation Biotransformation on Biotherapeutics. Analytical chemistry 95 (49) (2023)
Rachel Liuqing Shi, Michael A Dillon, Philip D Compton, William S Sawyer, John R Thorup, Mandy Kwong, Pamela Chan, Cecilia P C Chiu, Ran Li, Rajbharan Yadav, Genee Y Lee, Joshua G Gober, Zhiyu Li, Adel M ElSohly, Ayse Meric Ovacik, James T Koerber, Christoph Spiess, Jonathan L Josephs, John C Tran
High-Throughput Analyses of Therapeutic Antibodies Using High-Field Asymmetric Waveform Ion Mobility Spectrometry Combined with SampleStream and Intact Protein Mass Spectrometry. Analytical chemistry (2023)
Peiyin Wang, Liping L Sun, Maria Hristopoulos, Cecilia P C Chiu, Michael Dillon, Wei Yu Lin, Amy A Lo, Sreedevi Chalsani, Meghna Das Thakur, Kristin M Zimmerman Savill, Lionel Rougé, Patrick J Lupardus, Robert Piskol, Bushra Husain, Diego Ellerman, Vittal Shivva, Steven R Leong, Meric Ovacik, Klara Totpal, Yan Wu, Christoph Spiess, Genee Lee, Douglas D Leipold, Andrew G Polson
Novel Anti-LY6G6D/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Colorectal Cancer. Molecular cancer therapeutics 21 (6) (2022)
Rajbharan Yadav, Siddharth Sukumaran, Tanja S Zabka, Jinze Li, Amy Oldendorp, Gary Morrow, Arthur Reyes, Melissa Cheu, Jessica Li, Jeffrey J Wallin, Siao Tsai, Laura Sun, Peiyin Wang, Diego Ellerman, Christoph Spiess, Andy Polson, Eric G Stefanich, Amrita V Kamath, Meric A Ovacik
Nonclinical Pharmacokinetics and Pharmacodynamics Characterization of Anti-CD79b/CD3 T Cell-Dependent Bispecific Antibody Using a Surrogate Molecule: A Potential Therapeutic Agent for B Cell Malignancies. Pharmaceutics 14 (5) (2022)
Sivan Cohen, Shan Chung, Christoph Spiess, Victor Lundin, Eric Stefanich, Steven T Laing, Vanessa Clark, Jochen Brumm, Ying Zhou, Catherine Huang, Joyce Guerrero, Srividya Myneni, Rajbharan Yadav, Ketevan Siradze, Kun Peng
An integrated approach for characterizing immunogenic responses toward a bispecific antibody. mAbs 13 (1) (2021)
Madeleine K Ramos, Danielle Mandikian, Lauren N Sermeño, Anna King, Alecia T Dent, Jason Ho, Sheila Ulufatu, T Noelle Lombana, Christoph Spiess, Mary Ann T Go, Shang-Fan Yu, Amrita V Kamath, Gregory Z Ferl, C Andrew Boswell
Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration. Molecular cancer therapeutics 20 (10) (2021)
William S Sawyer, Neha Srikumar, Joseph Carver, Phillip Y Chu, Amy Shen, Ankai Xu, Ambrose J Williams, Christoph Spiess, Cong Wu, Yichin Liu, John C Tran
High-throughput antibody screening from complex matrices using intact protein electrospray mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America 117 (18) (2020)
T Noelle Lombana, Sharmila Rajan, Julie A Zorn, Danielle Mandikian, Eugene C Chen, Alberto Estevez, Victor Yip, Daniel D Bravo, Wilson Phung, Farzam Farahi, Sharon Viajar, Sophia Lee, Avinash Gill, Wendy Sandoval, Jianyong Wang, Claudio Ciferri, C Andrew Boswell, Marissa L Matsumoto, Christoph Spiess
Production, characterization, and in vivo half-life extension of polymeric IgA molecules in mice. mAbs 11 (6) (2019)
Dionysos Slaga, Diego Ellerman, T Noelle Lombana, Rajesh Vij, Ji Li, Maria Hristopoulos, Peiyin Wang, Jennifer Johnston, Amy Shelton, Elaine Mai, Kapil Gadkar, Amy A Lo, James T Koerber, Klara Totpal, Rodney Prell, Genee Lee, Christoph Spiess, Teemu T Junttila
Avidity-based binding to HER2 results in selective killing of HER2-overexpressing cells by anti-HER2/CD3. Science translational medicine 10 (463) (2019)
T Noelle Lombana, Marissa L Matsumoto, Amy M Berkley, Evangeline Toy, Ryan Cook, Yutian Gan, Changchun Du, Paul Schnier, Wendy Sandoval, Zhengmao Ye, Jill M Schartner, Jeong Kim, Christoph Spiess
High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies. mAbs 11 (1) (2018)
Kannan Sankar, Kam Hon Hoi, Yizhou Yin, Prasanna Ramachandran, Nisana Andersen, Amy Hilderbrand, Paul McDonald, Christoph Spiess, Qing Zhang
Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method. mAbs 10 (8) (2018)
Ankai Xu, Hok Seon Kim, Samarkand Estee, Sharon ViaJar, William J Galush, Avinash Gill, Isidro Hötzel, Greg A Lazar, Paul McDonald, Nisana Andersen, Christoph Spiess
Susceptibility of Antibody CDR Residues to Chemical Modifications Can Be Revealed Prior to Antibody Humanization and Aid in the Lead Selection Process. Molecular pharmaceutics 15 (10) (2018)
Ayse Meric Ovacik, Ji Li, Marie Lemper, Dimitry Danilenko, Nicola J Stagg, Mary Mathieu, Diego Ellerman, Vinita Gupta, Navdeep Kalia, Trung Nguy, Vicki Plaks, Clarissa David Johnson, Weiru Wang, Jochen Brumm, Bernard Fine, Teemu Junttila, Kedan Lin, Paul J Carter, Saileta Prabhu, Christoph Spiess, Amrita V Kamath
Single cell-produced and in vitro-assembled anti-FcRH5/CD3 T-cell dependent bispecific antibodies have similar in vitro and in vivo properties. mAbs 11 (2) (2018)