Science translational medicine

Keyphrases

Publications

volume 16, number 758, 2024

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Lopez Hart, Jibin Zhang, Viola Siegert, Marianne Remke, Xuesong Wang, Lei Yu, Joo Y Song, Girish Venkataraman, Wing C Chan, Zhenyu Jia, Maike Buchner, Tanya Siddiqi, Steven T Rosen, Alexey V Danilov, Lili Wang
MGA deletion leads to Richter's transformation by modulating mitochondrial OXPHOS. Science translational medicine 16 (758) (2024)
Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Lopez Hart, Jibin Zhang, Viola Siegert, Marianne Remke, Xuesong Wang, Lei Yu, Joo Y Song, Girish Venkataraman, Wing C Chan, Zhenyu Jia, Maike Buchner, Tanya Siddiqi, Steven T Rosen, Alexey V Danilov, Lili Wang
MGA deletion leads to Richter's transformation by modulating mitochondrial OXPHOS. Science translational medicine 16 (758) (2024)
Viviane Bechtold, Kinga K Smolen, Wivine Burny, Simone P de Angelis, Simon Delandre, Ahmed Essaghir, Arnaud Marchant, Cheikh Ndour, Martin Taton, Robbert G van der Most, Fabienne Willems, Arnaud M Didierlaurent
Functional and epigenetic changes in monocytes from adults immunized with an AS01-adjuvanted vaccine. Science translational medicine 16 (758) (2024)
Marloes van den Berg, Zhonghua Shi, Wout J Claassen, Pleuni Hooijman, Christopher T A Lewis, Jesper Løvind Andersen, Robbert J van der Pijl, Sylvia J P Bogaards, Stefan Conijn, Eva L Peters, Leon P L Begthel, Bas A Uijterwijk, Johan Lindqvist, Paul R Langlais, Armand R J Girbes, Sandra Stapel, Henk L Granzier, Kenneth S Campbell, Weikang Ma, Thomas C Irving, Darren T Hwee, James J Hartman, Fady I Malik, Marinus Paul, Albertus Beishuizen, Julien Ochala, Leo Heunks, Coen A C Ottenheijm
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients. Science translational medicine 16 (758) (2024)
Prabhu S Arunachalam, NaYoung Ha, S Moses Dennison, Rachel L Spreng, Kelly E Seaton, Peng Xiao, Yupeng Feng, Veronika I Zarnitsyna, Dmitri Kazmin, Mengyun Hu, Jordan M Santagata, Xia Xie, Kenneth A Rogers, Lisa M Shirreff, Claire Chottin, Alexandra J Spencer, Sheetij Dutta, Katherine Prieto, Jean-Philippe Julien, Mark Tomai, Christopher B Fox, François J Villinger, Adrian V S Hill, Georgia D Tomaras, Bali Pulendran
A comparative immunological assessment of multiple clinical-stage adjuvants for the R21 malaria vaccine in nonhuman primates. Science translational medicine 16 (758) (2024)
Steven G Reed, Darrick Carter
Make it a combo. Science translational medicine 16 (758) (2024)

volume 16, number 759, 2024

Nikole L Warner, Jacob Archer, Stephanie Park, Garima Singh, Kathryn M McFadden, Taishi Kimura, Katrina Nicholes, Adrian Simpson, Jason T Kaelber, David W Hawman, Heinrich Feldmann, Amit P Khandhar, Peter Berglund, Matthew R Vogt, Jesse H Erasmus
A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models. Science translational medicine 16 (759) (2024)
Prashanth Thevkar Nagesh, Yeonhee Cho, Yuan Zhuang, Mrigya Babuta, Marti Ortega-Ribera, Radhika Joshi, Veronika Lelakova, Arman Patel, Aditi Ashish Datta, Viliam Brezani, Yun-Cheng Hsieh, Adriana Ramos, Jeeval Mehta, Christopher J Copeland, Eleni Kanata, Zhenghui Gordon Jiang, Ioannis S Vlachos, John M Asara, null null, Gyongyi Szabo
In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis. Science translational medicine 16 (759) (2024)
Marisa Zallocchi, Sarath Vijayakumar, Jonathan Fleegel, Lyudmila Batalkina, Katyarina E Brunette, Dhaval Shukal, Zhiyong Chen, Olivier Devuyst, Huizhan Liu, David Z Z He, Ali Sajid Imami, Abdul-Rizaq Ali Hamoud, Robert McCullumsmith, Martin Conda-Sheridan, Luana Janaína De Campos, Jian Zuo
Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice. Science translational medicine 16 (759) (2024)
Nikole L Warner, Jacob Archer, Stephanie Park, Garima Singh, Kathryn M McFadden, Taishi Kimura, Katrina Nicholes, Adrian Simpson, Jason T Kaelber, David W Hawman, Heinrich Feldmann, Amit P Khandhar, Peter Berglund, Matthew R Vogt, Jesse H Erasmus
A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models. Science translational medicine 16 (759) (2024)
Emma van Groesen, Elma Mons, Ioli Kotsogianni, Melina Arts, Kamaleddin H M E Tehrani, Nicola Wade, Vladyslav Lysenko, Florence M Stel, Jordy T Zwerus, Stefania De Benedetti, Alexander Bakker, Parichita Chakraborty, Mario van der Stelt, Dirk-Jan Scheffers, Jairo Gooskens, Wiep Klaas Smits, Kirsty Holden, Peter S Gilmour, Joost J Willemse, Christopher A Hitchcock, Johan G C van Hasselt, Tanja Schneider, Nathaniel I Martin
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity. Science translational medicine 16 (759) (2024)
Jihoon Han, Jae Hoon Sul, Jeongmi Lee, Eunae Kim, Hark Kyun Kim, Minshik Chae, Jeein Lim, Jongho Kim, Chanhee Kim, Jun-Sik Kim, Yoonsuk Cho, Jae Hyung Park, Yong Woo Cho, Dong-Gyu Jo
Engineered exosomes with a photoinducible protein delivery system enable CRISPR-Cas-based epigenome editing in Alzheimer's disease. Science translational medicine 16 (759) (2024)
Emma van Groesen, Elma Mons, Ioli Kotsogianni, Melina Arts, Kamaleddin H M E Tehrani, Nicola Wade, Vladyslav Lysenko, Florence M Stel, Jordy T Zwerus, Stefania De Benedetti, Alexander Bakker, Parichita Chakraborty, Mario van der Stelt, Dirk-Jan Scheffers, Jairo Gooskens, Wiep Klaas Smits, Kirsty Holden, Peter S Gilmour, Joost J Willemse, Christopher A Hitchcock, Johan G C van Hasselt, Tanja Schneider, Nathaniel I Martin
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity. Science translational medicine 16 (759) (2024)

volume 16, number 760, 2024

Swati Shah, Jianhao Lai, Falguni Basuli, Neysha Martinez-Orengo, Reema Patel, Mitchell L Turner, Benjamin Wang, Zhen-Dan Shi, Suman Sourabh, Morteza Peiravi, Anna Lyndaker, Sichen Liu, Seyedmojtaba Seyedmousavi, Peter R Williamson, Rolf E Swenson, Dima A Hammoud
Development and preclinical validation of 2-deoxy 2-[ 18 F]fluorocellobiose as an Aspergillus -specific PET tracer. Science translational medicine 16 (760) (2024)
Xue Dong, Yinting Song, Yuming Liu, Xuejing Kou, Tianjing Yang, Samuel X Shi, Kai He, Yiming Li, Ziqi Li, Xueming Yao, Ju Guo, Bohao Cui, Ziru Wu, Yi Lei, Mei Du, Mei Chen, Heping Xu, Qiang Liu, Fu-Dong Shi, Xiaohong Wang, Hua Yan
Natural killer cells promote neutrophil extracellular traps and restrain macular degeneration in mice. Science translational medicine 16 (760) (2024)
David Lagier, Congli Zeng, David W Kaczka, Min Zhu, Kira Grogg, Sarah E Gerard, Joseph M Reinhardt, Gabriel Casulari Motta-Ribeiro, Azman Rashid, Tilo Winkler, Marcos F Vidal Melo
Mechanical ventilation guided by driving pressure optimizes local pulmonary biomechanics in an ovine model. Science translational medicine 16 (760) (2024)
Scarlett J Barker, Mai B Thayer, Chaeyoung Kim, David Tatarakis, Matthew J Simon, Rebekah Dial, Lizanne Greer Nilewski, Robert C Wells, Yinhan Zhou, Megan Afetian, Padma Akkapeddi, Alfred E Chappell, Kylie S Chew, Johann Chow, Allisa Clemens, Claire B Discenza, Jason C Dugas, Chrissa Dwyer, Timothy Earr, Connie Ha, Yvonne S Ho, David Huynh, Edwin I Lozano, Srini Jayaraman, Wanda Kwan, Cathal S Mahon, Michelle E Pizzo, Yaneth Robles-Colmenares, Elysia Roche, Laura Sanders, Alexander Stergioulis, Raymond Tong, Hai L Tran, Y Joy Yu Zuchero, Anthony A Estrada, Kapil Gadkar, Christopher M M Koth, Pascal E Sanchez, Robert G Thorne, Ryan J Watts, Thomas Sandmann, Lesley A Kane, Frank Rigo, Mark S Dennis, Joseph W Lewcock, Sarah L DeVos
Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier. Science translational medicine 16 (760) (2024)
Álvaro Quintanal-Villalonga
An identity crisis for lung cancer cells. Science translational medicine 16 (760) (2024)
David Lagier, Congli Zeng, David W Kaczka, Min Zhu, Kira Grogg, Sarah E Gerard, Joseph M Reinhardt, Gabriel Casulari Motta-Ribeiro, Azman Rashid, Tilo Winkler, Marcos F Vidal Melo
Mechanical ventilation guided by driving pressure optimizes local pulmonary biomechanics in an ovine model. Science translational medicine 16 (760) (2024)
Hui Chen, Stéphanie Moriceau, Adrien Joseph, Francois Mailliet, Sijing Li, Virginie Tolle, Philibert Duriez, Roland Dardennes, Sylvère Durand, Vincent Carbonnier, Gautier Stoll, Allan Sauvat, Sylvie Lachkar, Fanny Aprahamian, Carolina Alves Costa Silva, Hui Pan, Léa Montégut, Gerasimos Anagnostopoulos, Flavia Lambertucci, Omar Motiño, Uxía Nogueira-Recalde, Mélanie Bourgin, Misha Mao, Yuhong Pan, Alexandra Cerone, Erwan Boedec, Zelia L Gouveia, Federica Marmorino, Chiara Cremolini, Lisa Derosa, Laurence Zitvogel, Oliver Kepp, Carlos López-Otín, Maria Chiara Maiuri, Franck Perez, Philip Gorwood, Nicolas Ramoz, Franck Oury, Isabelle Martins, Guido Kroemer
Acyl-CoA binding protein for the experimental treatment of anorexia. Science translational medicine 16 (760) (2024)

volume 16, number 761, 2024

Pritesh Desai, Courtney E Karl, Baoling Ying, Chieh-Yu Liang, Tamara Garcia-Salum, Ana Carolina Santana, Felipe Ten-Caten, Joseph F Urban, Sayda M Elbashir, Darin K Edwards, Susan Pereira Ribeiro, Larissa B Thackray, Rafick-Pierre Sekaly, Michael S. Diamond
Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2 in mice. Science translational medicine 16 (761) (2024)
Zhen Lu, Ioannis I Verginadis, Motofumi Kumazoe, Gerardo M Castillo, Yao Yao, Rebecca E Guerra, Sandra Bicher, Menghao You, George McClung, Rong Qiu, Zebin Xiao, Zhen Miao, Subin S George, Daniel P Beiting, Takashi Nojiri, Yasutake Tanaka, Yoshinori Fujimura, Hiroaki Onda, Yui Hatakeyama, Akiko Nishimoto-Ashfield, Katrina Bykova, Wei Guo, Yi Fan, Nikolay M Buynov, J Alan Diehl, Ben Z Stanger, Hirofumi Tachibana, Terence P F Gade, Ellen Puré, Constantinos Koumenis, Elijah M Bolotin, Serge Y Fuchs
Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies. Science translational medicine 16 (761) (2024)
Ryutaro Kotaki, Saya Moriyama, Shintaro Oishi, Taishi Onodera, Yu Adachi, Eita Sasaki, Kota Ishino, Miwa Morikawa, Hiroaki Takei, Hidenori Takahashi, Tomohiro Takano, Ayae Nishiyama, Kohei Yumoto, Kazutaka Terahara, Masanori Isogawa, Takayuki Matsumura, Masaharu Shinkai, Yoshimasa Takahashi
Repeated Omicron exposures redirect SARS-CoV-2-specific memory B cell evolution toward the latest variants. Science translational medicine 16 (761) (2024)
Pritesh Desai, Courtney E Karl, Baoling Ying, Chieh-Yu Liang, Tamara Garcia-Salum, Ana Carolina Santana, Felipe Ten-Caten, Joseph F Urban, Sayda M Elbashir, Darin K Edwards, Susan Pereira Ribeiro, Larissa B Thackray, Rafick-Pierre Sekaly, Michael S. Diamond
Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2 in mice. Science translational medicine 16 (761) (2024)
Zhongcheng Mei, May A Khalil, Yizhan Guo, Dongge Li, Anirban Banerjee, Mojtaba Taheri, Christina M Kratzmeier, Kelly Chen, Christine L Lau, Irina G Luzina, Sergei P Atamas, Sivaveera Kandasamy, Daniel Kreisel, Andrew E Gelman, Elizabeth A Jacobsen, Alexander Sasha Krupnick
Stress-induced eosinophil activation contributes to postoperative morbidity and mortality after lung resection. Science translational medicine 16 (761) (2024)
Simone Bido, Melania Nannoni, Sharon Muggeo, Diana Gambarè, Giorgia Ruffini, Edoardo Niccolò Bellini, Laura Passeri, Silvia Iaia, Mirko Luoni, Martino Provinciali, Serena Gea Giannelli, Francesca Giannese, Dejan Lazarević, Silvia Gregori, Vania Broccoli
Microglia-specific IL-10 gene delivery inhibits neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease. Science translational medicine 16 (761) (2024)

volume 16, number 762, 2024

Ying Liu, Feng Wang, Dongxue Peng, Dan Zhang, Luping Liu, Jun Wei, Jian Yuan, Luyao Zhao, Huimin Jiang, Tingting Zhang, Yun-Xuan Li, Chenxi Zhao, Shuhua He, Jie Wu, Yechao Yan, Peitao Zhang, Chunyi Guo, Jiaming Zhang, Xia Li, Huan Gao, Ke Li
Activation and antitumor immunity of CD8 + T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid. Science translational medicine 16 (762) (2024)
Tomokazu S Sumida, Matthew R Lincoln, Liang He, Yongjin P Park, Mineto Ota, Akiko Oguchi, Raku Son, Alice Yi, Helen A Stillwell, Greta A Leissa, Keishi Fujio, Yasuhiro Murakawa, Alexander M Kulminski, Charles B Epstein, Bradley E Bernstein, Manolis Kellis, David A Hafler
An autoimmune transcriptional circuit drives FOXP3 + regulatory T cell dysfunction. Science translational medicine 16 (762) (2024)
Loretah Chibaya, Kelly D DeMarco, Christina F Lusi, Griffin I Kane, Meghan L Brassil, Chaitanya N Parikh, Katherine C Murphy, Shreya R Chowdhury, Junhui Li, Boyang Ma, Tiana E Naylor, Julia Cerrutti, Haruka Mori, Miranda Diaz-Infante, Jessica Peura, Jason R Pitarresi, Julie Lihua Zhu, Katherine A Fitzgerald, Prabhani U Atukorale, Marcus Ruscetti
Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer. Science translational medicine 16 (762) (2024)
Ying Liu, Feng Wang, Dongxue Peng, Dan Zhang, Luping Liu, Jun Wei, Jian Yuan, Luyao Zhao, Huimin Jiang, Tingting Zhang, Yun-Xuan Li, Chenxi Zhao, Shuhua He, Jie Wu, Yechao Yan, Peitao Zhang, Chunyi Guo, Jiaming Zhang, Xia Li, Huan Gao, Ke Li
Activation and antitumor immunity of CD8 + T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid. Science translational medicine 16 (762) (2024)
Loretah Chibaya, Kelly D DeMarco, Christina F Lusi, Griffin I Kane, Meghan L Brassil, Chaitanya N Parikh, Katherine C Murphy, Shreya R Chowdhury, Junhui Li, Boyang Ma, Tiana E Naylor, Julia Cerrutti, Haruka Mori, Miranda Diaz-Infante, Jessica Peura, Jason R Pitarresi, Julie Lihua Zhu, Katherine A Fitzgerald, Prabhani U Atukorale, Marcus Ruscetti
Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer. Science translational medicine 16 (762) (2024)
Tomokazu S Sumida, Matthew R Lincoln, Liang He, Yongjin P Park, Mineto Ota, Akiko Oguchi, Raku Son, Alice Yi, Helen A Stillwell, Greta A Leissa, Keishi Fujio, Yasuhiro Murakawa, Alexander M Kulminski, Charles B Epstein, Bradley E Bernstein, Manolis Kellis, David A Hafler
An autoimmune transcriptional circuit drives FOXP3 + regulatory T cell dysfunction. Science translational medicine 16 (762) (2024)
Jie Ma, Liyin Zhang, Xu Zhang, Lanlan Zhang, Hua Zhang, Yulei Zhu, Xingming Huang, Ting Zhang, Xiangdong Tang, Zhongwang Wang, Mei Chen, Qiang Pu, Liming Yang, Zhongwei Cao, Bi-Sen Ding
Inhibiting endothelial Rhoj blocks profibrotic vascular intussusception and angiocrine factors to sustain lung regeneration. Science translational medicine 16 (762) (2024)
Joshua D Bernstock, Jakob V E Gerstl, Pablo A Valdés, Gregory K Friedman, E Antonio Chiocca
Next-generation CAR T cell therapies for glioblastoma. Science translational medicine 16 (762) (2024)

volume 16, number 763, 2024

Soongwon Cho, Samy M Shaban, Ruihao Song, Haohui Zhang, Da Som Yang, Min-Jae Kim, Yirui Xiong, Xiuyuan Li, Kenneth Madsen, Sarena Wapnick, Shifan Zhang, Ziyu Chen, Jiwon Kim, Gianna Guinto, Michelle Li, Min-Kyu Lee, Ravi F Nuxoll, Shaghayegh Shajari, Jin Wang, Seongeun Son, Jihoon Shin, Alexander J Aranyosi, Donald E Wright, Tae-Il Kim, Roozbeh Ghaffari, Yonggang Huang, Dong Hwan Kim, John A Rogers
A skin-interfaced microfluidic platform supports dynamic sweat biochemical analysis during human exercise. Science translational medicine 16 (763) (2024)
Zhuo Chen, Wenxiang Ji, Wenxin Feng, Jingchuan Cui, Yuchen Wang, Fan Li, Jiachen Chen, Ziheng Guo, Liliang Xia, Xiaokuan Zhu, Xiaomin Niu, Yanshuang Zhang, Ziming Li, Alice Sze Tsai Wong, Shun Lu, Wei-Liang Xia
PTPRT loss enhances anti-PD-1 therapy efficacy by regulation of STING pathway in non-small cell lung cancer. Science translational medicine 16 (763) (2024)
Anjali Singh, César Boggiano, Dwight E Yin, Laura L Polakowski, Sai P Majji, Wolfgang W Leitner, Ofer Levy, Kristina De Paris
Precision adjuvants for pediatric vaccines. Science translational medicine 16 (763) (2024)
Xue Zhang, Adam Pines, Patrick Stetz, Andrea N Goldstein-Piekarski, Lan Xiao, Nan Lv, Leonardo Tozzi, Philip W Lavori, Mark B Snowden, Elizabeth M Venditti, Christopher G Engeland, Trisha Suppes, Olusola A Ajilore, Jun Ma, Leanne Maree Williams
Adaptive cognitive control circuit changes associated with problem-solving ability and depression symptom outcomes over 24 months. Science translational medicine 16 (763) (2024)
Ting-Ting Chang, You-Zhen Li, Hsiao-Wei Mo, Ching Chen, Liang-Yu Lin, Chia-Chi Chang, Jaw-Wen Chen
Inhibition of CCL7 improves endothelial dysfunction and vasculopathy in mouse models of diabetes mellitus. Science translational medicine 16 (763) (2024)

volume 16, number 764, 2024

João Luiz Silva-Filho, Vanessa Herder, Matthew P Gibbins, Monique Freire Santana, Gisely Cardoso de Melo, Michael J Haley, Carla Cristina Judice, Fernando Fonseca Almeida Val, Mayla Borba, Tatyana Almeida Tavella, Vanderson de Souza Sampaio, Charalampos Attipa, Fiona McMonagle, Derek W Wright, Marcus Vinícius Guimarães de Lacerda, Fabio Trindade Maranhão Costa, Kevin N Couper, Wuelton Marcelo Monteiro, Luiz Carlos de Lima Ferreira, Christopher Alan Moxon, Massimo Palmarini, Matthias Marti
A spatially resolved single-cell lung atlas integrated with clinical and blood signatures distinguishes COVID-19 disease trajectories. Science translational medicine 16 (764) (2024)
Ishtiaq Jeelani, Jae-Su Moon, Flávia Franco Cunha, Chanond A Nasamran, Seokhyun Jeon, Xinhang Zhang, Gautam K Bandyopadhyay, Katarzyna Dobaczewska, Zbigniew Mikulski, Mojgan Hosseini, Xiao Liu, Tatiana Kisseleva, David A Brenner, Seema Singh, Rohit Loomba, Minkyu Kim, Yun Sok Lee
HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis. Science translational medicine 16 (764) (2024)
Bijender Kumar, Anand Kamal Singh, Rafet Basar, Nadima Uprety, Ye Li, Huihui Fan, Ana Karen Nunez Cortes, Mecit Kaplan, Sunil Acharya, Hila Shaim, Anna C Xu, Manrong Wu, Emily Ensley, Dexing Fang, Pinaki P Banerjee, Luciana Melo Garcia, Silvia Tiberti, Paul Lin, Hind Rafei, Maliha Nuzhat Munir, Madison Moore, Mayra Shanley, Mayela Mendt, Lucila N Kerbauy, Bin Liu, Alexander Biederstädt, Elif Gokdemir, Susmita Ghosh, Kiran Kundu, Francia Reyes-Silva, Xin Ru Jiang, Xinhai Wan, April L Gilbert, Merve Dede, Vakul Mohanty, Jinzhuang Dou, Patrick Zhang, Enli Liu, Luis Muniz-Feliciano, Gary M Deyter, Abhinav K Jain, Juan José Rodríguez Sevilla, Simona Colla, Guillermo Garcia Manero, Elizabeth J Shpall, Ken Chen, Hussein A Abbas, Kunal Rai, Katayoun Rezvani, May Daher
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML. Science translational medicine 16 (764) (2024)
Sanjeeb Kumar Sahu, Pradeep Reddy, Jinlong Lu, Yanjiao Shao, Chao Wang, Mako Tsuji, Núñez-Delicado Estrella, Concepcion Rodriguez Esteban, Juan Carlos Izpisua Belmonte
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging. Science translational medicine 16 (764) (2024)
Alice Dejoux, Qianqian Zhu, Christelle Ganneau, Odile Richard-Le Goff, Ophélie Godon, Julien Lemaitre, Francis Relouzat, François Huetz, Aurélien Sokal, Alexis Vandenberghe, Cyprien Pecalvel, Lise Hunault, Thomas Derenne, Caitlin M Gillis, Bruno Iannascoli, Yidan Wang, Thierry Rose, Christel H Mertens, Pascale Nicaise-Roland, null null, Patrick England, Matthieu Mahevas, Luc de Chaisemartin, Roger Le Grand, Hélène Letscher, Frederick Saul, Cédric Pissis, Ahmed Haouz, Laurent Lionel Reber, Pascal Chappert, Friederike Jönsson, Didier Gaston Ebo, Gael A Millot, Sylvie Bay, Sylvie Chollet-Martin, Aurélie Gouel-Chéron, Pierre Bruhns
Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models. Science translational medicine 16 (764) (2024)

volume 16, number 765, 2024

Zin Z Khaing, Jannik Leyendecker, Jennifer N Harmon, Sananthan Sivakanthan, Lindsay N Cates, Jeffrey E Hyde, Melissa Krueger, Robb W Glenny, Matthew Bruce, Christoph P Hofstetter
Perfusion imaging metrics after acute traumatic spinal cord injury are associated with injury severity in rats and humans. Science translational medicine 16 (765) (2024)
Justin C Jagodinsky, Jessica M Vera, Won Jong Jin, Amanda G Shea, Paul A Clark, Raghava N Sriramaneni, Thomas C Havighurst, Ishan Chakravarthy, Raad H Allawi, KyungMann Kim, Paul M Harari, Paul M Sondel, Michael A Newton, Marka R Crittenden, Michael J Gough, Jessica R Miller, Irene M Ong, Zachary S Morris
Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade. Science translational medicine 16 (765) (2024)
Anushka Saha, Trirupa Chakraborty, Javad Rahimikollu, Hanxi Xiao, Lorena B Pereira de Oliveira, Timothy W Hand, Sukwan Handali, William Evan Secor, Lucia Alves de Oliveira Fraga, Jessica K Fairley, Jishnu Das, Aniruddh Sarkar
Deep humoral profiling coupled to interpretable machine learning unveils diagnostic markers and pathophysiology of schistosomiasis. Science translational medicine 16 (765) (2024)
Benoît Manfroi, Bui Thi Cuc, Aurélien Sokal, Alexis Vandenberghe, Sarah Temmam, Mikaël Attia, Mohamed El Behi, Francesco Camaglia, Ngan Thu Nguyen, Jelka Pohar, Layale Salem-Wehbe, Valentine Pottez-Jouatte, Sibyline Borzakian, Narcisse Elenga, Caroline Galeotti, Guillaume Morelle, Camille de Truchis de Lays, Michaela Semeraro, Anne-Sophie Romain, Mélodie Aubart, Naim Ouldali, Florence Mahuteau-Betzer, Claire Beauvineau, Elsa Amouyal, Romain Berthaud, Célia Crétolle, Marc Duval Arnould, Albert Faye, Mathie Lorrot, Grégoire Benoist, Nelly Briand, Marie Courbebaisse, Roland Martin, Peter Van Endert, Jean-Sébastien Hulot, Anne Blanchard, Eric Tartour, Maria C Leite-de-Moraes, Guillaume Lezmi, Mickael Ménager, Marine Luka, Claude-Agnès Reynaud, Jean-Claude Weill, Laetitia Languille, Marc Michel, Pascal Chappert, Thierry Mora, Aleksandra M Walczak, Marc Eloit, Petra Bacher, Alexander Scheffold, Matthieu Mahevas, Isabelle Sermet-Gaudelus, Simon Fillatreau
Preschool-age children maintain a distinct memory CD4 + T cell and memory B cell response after SARS-CoV-2 infection. Science translational medicine 16 (765) (2024)
Roeland Vanhauwaert, Julien Oury, Bernhardt Vankerckhoven, Christophe Steyaert, Stine Marie Jensen, Dana L E Vergoossen, Christa Kneip, Leah Santana, Jamie L Lim, Jaap J Plomp, Roy Augustinus, Shohei Koide, Christophe Blanchetot, Peter Ulrichts, Maartje G Huijbers, Karen Silence, Steven J Burden
ARGX-119 is an agonist antibody for human MuSK that reverses disease relapse in a mouse model of congenital myasthenic syndrome. Science translational medicine 16 (765) (2024)
Sebastian Ochoa, Amy P Hsu, Andrew J Oler, Dhaneshwar Kumar, Daniel Chauss, Jan Piet van Hamburg, Gustaaf G van Laar, Vasileios Oikonomou, Sundar Ganesan, Elise M N Ferré, Monica M Schmitt, Thomas DiMaggio, Princess Barber, Gregory M Constantine, Lindsey B Rosen, Paul G Auwaerter, Bhumika Gandhi, Jennifer L Miller, Rachel Eisenberg, Arye Rubinstein, Edith Schussler, Erjola Balliu, Vandana Shashi, Marta Aboza Garcia, Peter Olbrich, Kim My Le, Nanni Mamia, Saila Laakso, Pasi I Nevalainen, Juha Grönholm, Mikko R J Seppänen, Louis Boon, Gulbu Uzel, Luis Miguel Franco, Theo Heller, Karen K Winer, Rajarshi Ghosh, Bryce A Seifert, Magdalena Walkiewicz, Luigi Daniele Notarangelo, Qing Zhou, Ivona Aksentijevich, William A Gahl, Cliffton L Dalgard, Lalith Perera, Behdad Afzali, Sander W Tas, Steven M Holland, Michail S Lionakis
A deep intronic splice-altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion. Science translational medicine 16 (765) (2024)