Daniel O'Toole
Publication Activity (10 Years)
Publications (10 Years): 6
National University of Ireland - Galway
University of Dublin Trinity College (PHD)
Ireland
Senior Research Fellow Honorary Research Senior Lecturer :: Medicine
Ireland
Senior Research Fellow Honorary Research Senior Lecturer :: Medicine
Ireland
Senior Researcher: Discipline Of Medicine and Orbsen Therapeutics Inc. SFI Industry Fellow Areas of study include: Development of industry host cell based therapeutic for lung and other medical applications Exploring medical applications for other elements of industry host intellectual property portfolio Continuing research interests in disciplines Medicine and Anaesthesia :: Medicine
Ireland
Research Fellow: Jan 2006 to Dec 2008 Senior Researcher: Jan 2009 to Dec 2013 Under the direction of: Prof. John Laffey Areas of study include: Hypercapnic acidosis in the injured lung epithelium and endothelium Modification of stem cells with genes to aid targetting and function Construction of novel and inducible lentiviral and AAV vectors Cell signalling in a rat model of myocardial infarction Ventilator induced lung injury pathology and treatment Polymer aided delivery of superoxide scavengers to the lung (with Abhay Pandit, NUIG) Polymer aided delivery of DNA vaccines to the lung (with Abhay Pandit, NUIG) Human ECSIT protein structure and function (with Paul Moynagh, NUIM) Adenyl cyclase activity in acute lung injury (with Martin Cann, University of Durham) Specific MSC subpopulation engraftment and effects in the injured lung (with Orbsen Therapeutics, Ireland) Duties include: Co-PI on MSc (1), MD (3) and PhD (5) students :: Anaesthesia
Ireland
Research Fellow Under the direction of: Prof. Paul Moynagh Areas of study included: Mediators of Toll Like Receptor signalling The interaction of adenosine and dopamine receptors in the neuron Tolerisation to LPS in the macrophage Myosin Light Chain Kinase in maintenance of the gut wall Anti-inflammatory effects of endocannabinoid analogues Statin function in secondary signalling Duties included: Extensive PhD student supervision Undergraduate project design and management Lecturing and tutorial duties Laboratory EPA liaison :: Pharmacology
Ireland
Collection and preparation of patient blood for analysis by flame chromatography
Ireland
PHD :: Biochemistry
Ireland
BSC :: Biochemistry
- Hector Gonzalez, Sean McCarthy, Claire Masterson, Declan Byrnes, Ignacio Sallent, Emma Horan, Stephen J Elliman, Gabriele Vella, Adriele P Mello, Johnatas D Silva, Anna D Krasnodembskaya, Ronan MacLoughlin, John G Laffey, Daniel O'Toole
- Sean D McCarthy, Maura A Tilbury, Claire H Masterson, Ronan MacLoughlin, Héctor E González, John G Laffey, J Gerard Wall, Daniel O'Toole
- Senthilkumar Alagesan, Jack Brady, Declan Byrnes, Juan Fandiño, Claire Masterson, Sean McCarthy, John Laffey, Daniel O'Toole
- Claire Masterson, Shahd Horie, Sean D McCarthy, Hector Gonzalez, Declan Byrnes, Jack Brady, Juan Fandiño, John Gerard Laffey, Daniel O'Toole