David A Cairns (D A Cairns, D Cairns, David Cairns)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 33

Top Topics

Multiple Myeloma

Neoadjuvant Chemotherapy

Top Venues

Blood cancer journal

British journal of haematology

Bone marrow transplantation

This page only lists publications with an associated author ORCID identifier.

Publications

Ruth M de Tute, Curly T C M Morris, David A Cairns, Julia M Brown, Jamie Cavenagh, A John Ashcroft, John A Snowden, Kwee Yong, Eleni Tholouli, Matthew Jenner, Anna Hockaday, Mark T Drayson, Treen C M Morris, Andy C Rawstron, Roger G Owen
Impact of minimal residual disease (MRD) in salvage autologous stem cell transplantation for relapsed myeloma: results from the NCRI Myeloma X (intensive) trial. Bone marrow transplantation 59 (3) (2024)
Ruth M de Tute, Curly T C M Morris, David A Cairns, Julia M Brown, Jamie Cavenagh, A John Ashcroft, John A Snowden, Kwee Yong, Eleni Tholouli, Matthew Jenner, Anna Hockaday, Mark T Drayson, Treen C M Morris, Andy C Rawstron, Roger G Owen
Impact of minimal residual disease (MRD) in salvage autologous stem cell transplantation for relapsed myeloma: results from the NCRI Myeloma X (intensive) trial. Bone marrow transplantation 59 (3) (2024)
Hannah V Giles, Mark T Drayson, B Kishore, Charlotte Pawlyn, Martin F Kaiser, Curly T C M Morris, R de Tute, R G Owen, David A Cairns, T Menzies, F E Davies, G J Morgan, Guy Pratt, G H Jackson
Progression free survival of myeloma patients who become IFE-negative correlates with the detection of residual monoclonal free light chain (FLC) by mass spectrometry. Blood cancer journal 14 (1) (2024)
Ruth M de Tute, Curly T C M Morris, David A Cairns, Julia M Brown, Jamie Cavenagh, A John Ashcroft, John A Snowden, Kwee Yong, Eleni Tholouli, Matthew Jenner, Anna Hockaday, Mark T Drayson, Treen C M Morris, Andy C Rawstron, Roger G Owen
Impact of minimal residual disease (MRD) in salvage autologous stem cell transplantation for relapsed myeloma: results from the NCRI Myeloma X (intensive) trial. Bone marrow transplantation (2024)
Charlotte Pawlyn, Schjesvold Fredrik, David A Cairns, L J Wei, Faith Davies, Omar Nadeem, Haifaa Abdulhaq, Maria-Victoria Mateos-Manteca, Jacob P Laubach, Katja C Weisel, Heinz Ludwig, Sundararajan Vincent Rajkumar, Pieter Sonneveld, Graham H Jackson, Gareth Morgan, Paul Gerard Richardson
Progression-free survival as a surrogate endpoint in myeloma clinical trials: an evolving paradigm. Blood cancer journal 14 (1) (2024)
Charlotte Pawlyn, Schjesvold Fredrik, David A Cairns, L J Wei, Faith Davies, Omar Nadeem, Haifaa Abdulhaq, Maria-Victoria Mateos-Manteca, Jacob P Laubach, Katja C Weisel, Heinz Ludwig, Sundararajan Vincent Rajkumar, Pieter Sonneveld, Graham H Jackson, Gareth Morgan, Paul Gerard Richardson
Progression-free survival as a surrogate endpoint in myeloma clinical trials: an evolving paradigm. Blood cancer journal 14 (1) (2024)
Hannah V Giles, Mark T Drayson, B Kishore, Charlotte Pawlyn, Martin F Kaiser, Curly T C M Morris, R de Tute, R G Owen, David A Cairns, T Menzies, F E Davies, G J Morgan, Guy Pratt, G H Jackson
Progression free survival of myeloma patients who become IFE-negative correlates with the detection of residual monoclonal free light chain (FLC) by mass spectrometry. Blood cancer journal 14 (1) (2024)
Ruth M de Tute, Curly T C M Morris, David A Cairns, Julia M Brown, Jamie Cavenagh, A John Ashcroft, John A Snowden, Kwee Yong, Eleni Tholouli, Matthew Jenner, Anna Hockaday, Mark T Drayson, Treen C M Morris, Andy C Rawstron, Roger G Owen
Impact of minimal residual disease (MRD) in salvage autologous stem cell transplantation for relapsed myeloma: results from the NCRI Myeloma X (intensive) trial. Bone marrow transplantation 59 (3) (2024)
Ruth M de Tute, Curly T C M Morris, David A Cairns, Julia M Brown, Jamie Cavenagh, A John Ashcroft, John A Snowden, Kwee Yong, Eleni Tholouli, Matthew Jenner, Anna Hockaday, Mark T Drayson, Treen C M Morris, Andy C Rawstron, Roger G Owen
Impact of minimal residual disease (MRD) in salvage autologous stem cell transplantation for relapsed myeloma: results from the NCRI Myeloma X (intensive) trial. Bone marrow transplantation 59 (3) (2024)
Hannah V Giles, Mark T Drayson, B Kishore, Charlotte Pawlyn, Martin F Kaiser, Curly T C M Morris, R de Tute, R G Owen, David A Cairns, T Menzies, F E Davies, G J Morgan, Guy Pratt, G H Jackson
Progression free survival of myeloma patients who become IFE-negative correlates with the detection of residual monoclonal free light chain (FLC) by mass spectrometry. Blood cancer journal 14 (1) (2024)
Charlotte Pawlyn, Schjesvold Fredrik, David A Cairns, L J Wei, Faith Davies, Omar Nadeem, Haifaa Abdulhaq, Maria-Victoria Mateos-Manteca, Jacob P Laubach, Katja C Weisel, Heinz Ludwig, Sundararajan Vincent Rajkumar, Pieter Sonneveld, Graham H Jackson, Gareth Morgan, Paul Gerard Richardson
Progression-free survival as a surrogate endpoint in myeloma clinical trials: an evolving paradigm. Blood cancer journal 14 (1) (2024)
Hannah V Giles, Mark T Drayson, B Kishore, Charlotte Pawlyn, Martin F Kaiser, Curly T C M Morris, R de Tute, R G Owen, David A Cairns, T Menzies, F E Davies, G J Morgan, Guy Pratt, G H Jackson
Progression free survival of myeloma patients who become IFE-negative correlates with the detection of residual monoclonal free light chain (FLC) by mass spectrometry. Blood cancer journal 14 (1) (2024)
James R Platt, Christopher J M Williams, Zoe Craig, David A Cairns, James C Glasbey, Dion G Morton, Jenny F Seligmann
Personalizing neoadjuvant chemotherapy for locally advanced colon cancer: protocols for the international phase III FOxTROT2 and FOxTROT3 randomized controlled trials. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2023)
James R Platt, Christopher J M Williams, Zoe Craig, David A Cairns, James C Glasbey, Dion G Morton, Jenny F Seligmann
Personalizing neoadjuvant chemotherapy for locally advanced colon cancer: protocols for the international phase III FOxTROT2 and FOxTROT3 randomized controlled trials. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 25 (3) (2023)
Aikaterini Panopoulou, David A Cairns, Amy Elizabeth Holroyd, Isabel Nichols, Nikita Cray, Charlotte Pawlyn, Curly T C M Morris, Mark T Drayson, Kevin D Boyd, Faith E Davies, Matthew W Jenner, Gareth J Morgan, Roger G Owen, Richard S Houlston, Graham H Jackson, Martin F Kaiser
Optimizing the value of lenalidomide maintenance by genetic profiling - an analysis of 556 Myeloma XI trial patients. Blood (2022)
Ruth M de Tute, Charlotte Pawlyn, David A Cairns, Faith E Davies, Tom Menzies, Andrew C Rawstron, John R Jones, Anna Hockaday, Rowena Henderson, Curly T C M Morris, Mark T Drayson, Matthew W Jenner, Martin F Kaiser, Walter M Gregory, Gareth J Morgan, Graham H Jackson, Roger G Owen
Minimal Residual Disease After Autologous Stem-Cell Transplant for Patients With Myeloma: Prognostic Significance and the Impact of Lenalidomide Maintenance and Molecular Risk. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (25) (2022)
Aikaterini Panopoulou, David A Cairns, Amy Elizabeth Holroyd, Isabel Nichols, Nikita Cray, Charlotte Pawlyn, Curly T C M Morris, Mark T Drayson, Kevin D Boyd, Faith E Davies, Matthew W Jenner, Gareth J Morgan, Roger G Owen, Richard S Houlston, Graham H Jackson, Martin F Kaiser
Optimizing the value of lenalidomide maintenance by genetic profiling - an analysis of 556 Myeloma XI trial patients. Blood (2022)
Matthew W Jenner, Charlotte Pawlyn, Faith E Davies, Tom Menzies, Anna Hockaday, Catherine Olivier, John R Jones, Kamuraj Karunanithi, Jindriska Lindsay, Bhuvan Kishore, Curly T C M Morris, Mark T Drayson, Martin F Kaiser, Roger G Owen, Walter Gregory, David A Cairns, Gareth J Morgan, Graham H Jackson, null null
The addition of vorinostat to lenalidomide maintenance for patients with newly diagnosed multiple myeloma of all ages: results from 'Myeloma XI', a multicentre, open-label, randomised, phase III trial. British journal of haematology (2022)
Charles Agbuduwe, Gulnaz Iqbal, David A Cairns, Tom Menzies, Janet Dunn, Walter Gregory, Martin F Kaiser, Roger Owen, Charlotte Pawlyn, J Anthony Child, Faith Davies, Gareth J Morgan, Graham H Jackson, Mark T Drayson, Supratik Basu
Clinical characteristics and outcomes of IgD myeloma: experience across UK national trials. Blood advances 6 (17) (2022)
Matthew W Jenner, Charlotte Pawlyn, Faith E Davies, Tom Menzies, Anna Hockaday, Catherine Olivier, John R Jones, Kamaraj Karunanithi, Jindriska Lindsay, Bhuvan Kishore, Curly T C M Morris, Mark T Drayson, Martin F Kaiser, Roger G Owen, Walter Gregory, David A Cairns, Gareth J Morgan, Graham H Jackson, null null
The addition of vorinostat to lenalidomide maintenance for patients with newly diagnosed multiple myeloma of all ages: results from 'Myeloma XI', a multicentre, open-label, randomised, phase III trial. British journal of haematology (2022)
Matthew W Jenner, Charlotte Pawlyn, Faith E Davies, Tom Menzies, Anna Hockaday, Catherine Olivier, John R Jones, Kamuraj Karunanithi, Jindriska Lindsay, Bhuvan Kishore, Curly T C M Morris, Mark T Drayson, Martin F Kaiser, Roger G Owen, Walter Gregory, David A Cairns, Gareth J Morgan, Graham H Jackson, null null
The addition of vorinostat to lenalidomide maintenance for patients with newly diagnosed multiple myeloma of all ages: results from 'Myeloma XI', a multicentre, open-label, randomised, phase III trial. British journal of haematology (2022)
Mattia D'Agostino, David A Cairns, Juan-José Lahuerta, Ruth Wester, Uta Bertsch, Anders Waage, Elena Zamagni, Maria-Victoria Mateos-Manteca, Daniele Dall'Olio, Niels W C J van de Donk, Graham H Jackson, Serena Rocchi, Hans J Salwender, Joan Bladé Creixenti, Bronno van der Holt, Gastone C Castellani, Francesca Bonello, Andrea Capra, Elias Karl Mai, Jan Dürig, Francesca Gay, Sonja Zweegman, Michele Cavo, Martin F Kaiser, Hartmut Goldschmidt, Jesús María Hernández-Rivas, Alessandra Larocca, Curly T C M Morris, Jesús San F Miguel, Mario Boccadoro, Pieter Sonneveld
Second Revision of the International Staging System (R2-ISS) for Overall Survival in Multiple Myeloma: A European Myeloma Network (EMN) Report Within the HARMONY Project. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (29) (2022)
Hannah Victoria Giles, Mark A Cook, Mark Trehane Drayson, Gordon Cook, Nicola Jane Wright, Simon John North, Stephen Harding, David A Cairns, Anna Hockaday, Martin F Kaiser, Paul Moss, Faith E Davies, Gareth J Morgan, Graham Jackson, Guy Pratt
Redefining Non-measurable Multiple Myeloma Using Mass Spectrometry. Blood (2021)
James Croft, Sidra Ellis, Amy L Sherborne, Kim Sharp, Amy Price, Matthew W Jenner, Mark T Drayson, Roger G Owen, Sally Chown, Jindriska Lindsay, Kamaraj Karunanithi, Hannah Hunter, Walter Martin Gregory, Faith E Davies, Gareth J Morgan, Curly T C M Morris, Lilit Atanesyan, Suvi Savola, David A Cairns, Graham Jackson, Richard S Houlston, Martin F Kaiser
Copy number evolution and its relationship with patient outcome-an analysis of 178 matched presentation-relapse tumor pairs from the Myeloma XI trial. Leukemia 35 (7) (2020)
Ceri A Bygrave, Charlotte Pawlyn, Faith Davies, Zoe Craig, David A Cairns, Anna Hockaday, Matthew Jenner, Gordon Cook, Mark Drayson, Roger Owen, Walter Gregory, Gareth Morgan, Graham Jackson, Martin F Kaiser
Early relapse after high-dose melphalan autologous stem cell transplant predicts inferior survival and is associated with high disease burden and genetically high-risk disease in multiple myeloma. British journal of haematology 193 (3) (2020)
Vallari Shah, Amy L Sherborne, David C Johnson, Sidra Ellis, Amy Price, Farzana Chowdhury, Jack Kendall, Matthew W Jenner, Mark T Drayson, Roger G Owen, Walter M Gregory, Gareth J Morgan, Faith E Davies, Curly T C M Morris, David A Cairns, Richard S Houlston, Graham Jackson, Martin F Kaiser, null null
Predicting ultrahigh risk multiple myeloma by molecular profiling: an analysis of newly diagnosed transplant eligible myeloma XI trial patients. Leukemia 34 (11) (2020)
Graham H Jackson, Charlotte Pawlyn, David A Cairns, Alina Striha, Corinne Collett, Anna Waterhouse, John R Jones, Jamie Wilson, Craig Taylor, Bhuvan Kishore, Mamta Garg, Cathy D Williams, Kamaraj Karunanithi, Jindriska Lindsay, Matthew W Jenner, Curly T C M Morris, Nigel H Russell, Mark T Drayson, Martin F Kaiser, Roger G Owen, Walter M Gregory, Faith E Davies, Gareth J Morgan, null null
Optimising the value of immunomodulatory drugs during induction and maintenance in transplant ineligible patients with newly diagnosed multiple myeloma: results from Myeloma XI, a multicentre, open-label, randomised, Phase III trial. British journal of haematology 192 (5) (2020)
Gordon Cook, Kara-Louise Royle, Sheila O'Connor, David A Cairns, A John Ashcroft, Cathy D Williams, Anna Hockaday, Jamie D Cavenagh, John A Snowden, Debo Ademokun, Eleni Tholouli, Vivienne E Andrews, Matthew Jenner, Christopher Parrish, Kwee L Yong, Jim Cavet, Hannah Hunter, Jenny M Bird, Guy Pratt, Mark T Drayson, Julia M Brown, Treen C M Morris, null null
The impact of cytogenetics on duration of response and overall survival in patients with relapsed multiple myeloma (long-term follow-up results from BSBMT/UKMF Myeloma X Relapse [Intensive]): a randomised, open-label, phase 3 trial. British journal of haematology 185 (3) (2019)
Charlotte Pawlyn, David A Cairns, Martin Kaiser, Alina Striha, John Jones, Vallari Shah, Matthew Jenner, Mark Drayson, Roger Owen, Walter Martin Gregory, Gordon Cook, Gareth Morgan, Graham Jackson, Faith Davies
The relative importance of factors predicting outcome for myeloma patients at different ages: results from 3894 patients in the Myeloma XI trial. Leukemia 34 (2) (2019)
Jennifer L J Heaney, John P Campbell, Gulnaz Iqbal, David A Cairns, Alex Richter, J Anthony Child, Walter Gregory, Graham Jackson, Martin Kaiser, Roger Owen, Faith Davies, Gareth Morgan, Janet Dunn, Mark T Drayson
Characterisation of immunoparesis in newly diagnosed myeloma and its impact on progression-free and overall survival in both old and recent myeloma trials. Leukemia 32 (8) (2018)
Kara-Louise Royle, Walter M Gregory, David A Cairns, Sue E Bell, Gordon Cook, Roger G Owen, Mark T Drayson, Faith E Davies, Graham H Jackson, Gareth J Morgan, J Anthony Child
Quality of life during and following sequential treatment of previously untreated patients with multiple myeloma: findings of the Medical Research Council Myeloma IX randomised study. British journal of haematology 182 (6) (2018)
V Shah, A L Sherborne, Brian A Walker, David C Johnson, E M Boyle, S Ellis, D B Begum, P Z Proszek, J R Jones, Charlotte Pawlyn, S Savola, M W Jenner, M T Drayson, R G Owen, R S Houlston, David A Cairns, W M Gregory, G Cook, F E Davies, G H Jackson, G J Morgan, M F Kaiser
Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients. Leukemia 32 (1) (2017)
David C Johnson, Niels Weinhold, Jonathan S Mitchell, Bowang Chen, Martin Kaiser, Dil B Begum, Jens Hillengass, Uta Bertsch, Walter A Gregory, David A Cairns, Graham H Jackson, Asta Försti, Jolanta Nickel, Per Hoffmann, Markus M Nöethen, Owen W Stephens, Bart Barlogie, Faith E Davis, Kari Hemminki, Hartmut Goldschmidt, Richard S Houlston, Gareth J Morgan
Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma. Nature communications 7 (2016)
D C Johnson, N Weinhold, J Mitchell, B Chen, O W Stephens, A Försti, J Nickel, M Kaiser, W A Gregory, David A Cairns, G H Jackson, P Hoffmann, M M Noethen, J Hillengass, U Bertsch, B Barlogie, F E Davis, K Hemminki, H Goldschmidt, R S Houlston, G J Morgan
Genetic factors influencing the risk of multiple myeloma bone disease. Leukemia 30 (4) (2015)