Second Revision of the International Staging System (R2-ISS) for Overall Survival in Multiple Myeloma: A European Myeloma Network (EMN) Report Within the HARMONY Project.
Mattia D'AgostinoDavid A CairnsJuan-José LahuertaRuth WesterUta BertschAnders WaageElena ZamagniMaria-Victoria Mateos-MantecaDaniele Dall'OlioNiels W C J van de DonkGraham H JacksonSerena RocchiHans J SalwenderJoan Bladé CreixentiBronno van der HoltGastone C CastellaniFrancesca BonelloAndrea CapraElias Karl MaiJan DürigFrancesca GaySonja ZweegmanMichele CavoMartin F KaiserHartmut GoldschmidtJesús María Hernández-RivasAlessandra LaroccaCurly T C M MorrisJesús San F MiguelMario BoccadoroPieter SonneveldPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
The R2-ISS is a simple prognostic staging system allowing a better stratification of patients with intermediate-risk NDMM. The additive nature of this score fosters its future implementation with new prognostic variables.