David A Knowles

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 13

Top Venues

Nature genetics

PNAS nexus

PLoS computational biology

bioRxiv : the preprint server for biology

Columbia University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Columbia University

United States

Assistant Professor :: Computer Science

New York Genome Center

United States

Core Faculty Member

Publications

Rockwell J Weiner, Chirag Lakhani, David A Knowles, Gamze Gürsoy
LDmat: efficiently queryable compression of linkage disequilibrium matrices. Bioinformatics (Oxford, England) 39 (2) (2023)
Brielin C Brown, John A Morris, Tuuli Lappalainen, David A Knowles
Large-scale causal discovery using interventional data sheds light on the regulatory network architecture of blood traits. bioRxiv : the preprint server for biology (2023)
N Shashaank, Mahalakshmi Somayaji, Mattia Miotto, Eugene V Mosharov, Emily A Makowicz, David A Knowles, Giancarlo Ruocco, David L Sulzer
Computational models of dopamine release measured by fast scan cyclic voltammetry in vivo. PNAS nexus 2 (3) (2023)
Hans-Hermann Wessels, Andrew Stirn, Alejandro Méndez-Mancilla, Eric J Kim, Sydney K Hart, David A Knowles, Neville E Sanjana
Prediction of on-target and off-target activity of CRISPR-Cas13d guide RNAs using deep learning. Nature biotechnology (2023)
Megan D Schertzer, Andrew Stirn, Keren Isaev, Laura Pereira, Anjali Das, Claire Harbison, Stella H Park, Hans-Hermann Wessels, Neville E Sanjana, David A Knowles
Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox. bioRxiv : the preprint server for biology (2023)
N Shashaank, Mahalakshmi Somayaji, Mattia Miotto, Eugene V Mosharov, Emily A Makowicz, David A Knowles, Giancarlo Ruocco, David L Sulzer
Computational models of dopamine release measured by fast scan cyclic voltammetry in vivo. PNAS nexus 2 (3) (2023)
Rockwell J Weiner, Chirag Lakhani, David A Knowles, Gamze Gürsoy
LDmat: efficiently queryable compression of linkage disequilibrium matrices. Bioinformatics (Oxford, England) 39 (2) (2023)
Stephen Malina, Daniel Cizin, David A Knowles
Deep mendelian randomization: Investigating the causal knowledge of genomic deep learning models. PLoS computational biology 18 (10) (2022)
Michael Wainberg, Nicholas A Sinnott-Armstrong, Nicholas Mancuso, Alvaro N Barbeira, David A Knowles, David Golan, Raili Ermel, Arno Ruusalepp, Thomas Quertermous, Ke Hao, Johan L M Bjorkegren, Hae Kyung Im, Bogdan Pasaniuc, Manuel A Rivas, Anshul Kundaje
Opportunities and challenges for transcriptome-wide association studies. Nature genetics 51 (4) (2019)
David A Knowles, Gina Bouchard, Sylvia Plevritis
Sparse discriminative latent characteristics for predicting cancer drug sensitivity from genomic features. PLoS computational biology 15 (5) (2019)
David A Knowles, Courtney K Burrows, John D Blischak, Kristen M Patterson, Daniel J Serie, Nadine Norton, Carole Ober, Jonathan K Pritchard, Yoav Gilad
Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes. eLife 7 (2018)
Yang I Li, David A Knowles, Jack Humphrey, Alvaro N Barbeira, Scott P Dickinson, Hae Kyung Im, Jonathan K Pritchard
Annotation-free quantification of RNA splicing using LeafCutter. Nature genetics 50 (1) (2017)
David A Knowles, Joe R Davis, Hilary Edgington, Anil Raj, Marie-Julie Favé, Xiaowei Zhu, James B Potash, Myrna M Weissman, Jianxin Shi, Douglas F Levinson, Philip Awadalla, Sara Mostafavi, Stephen B Montgomery, Alexis J Battle
Allele-specific expression reveals interactions between genetic variation and environment. Nature methods 14 (7) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

David A Knowles