Neville E Sanjana (Neville Sanjana)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 42

Top Topics

Transcription Factor

Dna Methylation

Muscular Dystrophy

Top Venues

bioRxiv : the preprint server for biology

The Journal of experimental medicine

Nature communications

Nature biotechnology

This page only lists publications with an associated author ORCID identifier.

Publications

Júlia Domingo, Mariia Minaeva, John A Morris, Sam Ghatan, Marcello Ziosi, Neville E Sanjana, Tuuli Lappalainen
Non-linear transcriptional responses to gradual modulation of transcription factor dosage. bioRxiv : the preprint server for biology (2024)
John R Ferrarone, Jerin Thomas, Arun M Unni, Yuxiang Zheng, Michal J Nagiec, Eric E Gardner, Oksana Mashadova, Kate Li, Nikos Koundouros, Antonino Montalbano, Meer Mustafa, Lewis C Cantley, John Blenis, Neville E Sanjana, Harold Varmus
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
John R Ferrarone, Jerin Thomas, Arun M Unni, Yuxiang Zheng, Michal J Nagiec, Eric E Gardner, Oksana Mashadova, Kate Li, Nikos Koundouros, Antonino Montalbano, Meer Mustafa, Lewis C Cantley, John Blenis, Neville E Sanjana, Harold Varmus
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Júlia Domingo, Mariia Minaeva, John A Morris, Marcello Ziosi, Neville E Sanjana, Tuuli Lappalainen
Non-linear transcriptional responses to gradual modulation of transcription factor dosage. bioRxiv : the preprint server for biology (2024)
John R Ferrarone, Jerin Thomas, Arun M Unni, Yuxiang Zheng, Michal J Nagiec, Eric E Gardner, Oksana Mashadova, Kate Li, Nikos Koundouros, Antonino Montalbano, Meer Mustafa, Lewis C Cantley, John Blenis, Neville E Sanjana, Harold Varmus
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Sydney K Hart, Hans-Hermann Wessels, Alejandro Méndez-Mancilla, Simon Müller, Gediminas Drabavicius, Olivia Choi, Neville E Sanjana
Low copy CRISPR-Cas13d mitigates collateral RNA cleavage. bioRxiv : the preprint server for biology (2024)
John R Ferrarone, Jerin Thomas, Arun M Unni, Yuxiang Zheng, Michal J Nagiec, Eric E Gardner, Oksana Mashadova, Kate Li, Nikos Koundouros, Antonino Montalbano, Meer Mustafa, Lewis C Cantley, John Blenis, Neville E Sanjana, Harold Varmus
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Júlia Domingo, Mariia Minaeva, John A Morris, Marcello Ziosi, Neville E Sanjana, Tuuli Lappalainen
Non-linear transcriptional responses to gradual modulation of transcription factor dosage. bioRxiv : the preprint server for biology (2024)
Júlia Domingo, Mariia Minaeva, John A Morris, Sam Ghatan, Marcello Ziosi, Neville E Sanjana, Tuuli Lappalainen
Non-linear transcriptional responses to gradual modulation of transcription factor dosage. bioRxiv : the preprint server for biology (2024)
Júlia Domingo, Mariia Minaeva, John A Morris, Sam Ghatan, Marcello Ziosi, Neville E Sanjana, Tuuli Lappalainen
Non-linear transcriptional responses to gradual modulation of transcription factor dosage. bioRxiv : the preprint server for biology (2024)
Wei Wei, Mitchell Jon Geer, Xinyi Guo, Igor Dolgalev, Neville E Sanjana, Benjamin G Neel
Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition. The Journal of experimental medicine 220 (5) (2023)
Wei Wei, Mitchell Jon Geer, Xinyi Guo, Igor Dolgalev, Neville E Sanjana, Benjamin G Neel
Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition. The Journal of experimental medicine 220 (5) (2023)
Wei Wei, Mitchell Jon Geer, Xinyi Guo, Igor Dolgalev, Neville E Sanjana, Benjamin G Neel
Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition. The Journal of experimental medicine 220 (5) (2023)
Congyi Lu, Görkem Garipler, Chao Dai, Timothy Roush, Jose Salome-Correa, Alex Martin, Noa Liscovitch-Brauer, Esteban Orlando Mazzoni, Neville E Sanjana
Essential transcription factors for induced neuron differentiation. Nature communications 14 (1) (2023)
John A Morris, Christina M Caragine, Zharko Daniloski, Júlia Domingo, Timothy Barry, Lu Lu, Kyrie Davis, Marcello Ziosi, Dafni A Glinos, Stephanie Hao, Eleni P Mimitou, Peter Smibert, Kathryn Roeder, Eugene Katsevich, Tuuli Lappalainen, Neville E Sanjana
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens. Science (New York, N.Y.) 380 (6646) (2023)
Wei Wei, Mitchell Jon Geer, Xinyi Guo, Igor Dolgalev, Neville E Sanjana, Benjamin G Neel
Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition. The Journal of experimental medicine 220 (5) (2023)
Hans-Hermann Wessels, Andrew Stirn, Alejandro Méndez-Mancilla, Eric J Kim, Sydney K Hart, David A Knowles, Neville E Sanjana
Prediction of on-target and off-target activity of CRISPR-Cas13d guide RNAs using deep learning. Nature biotechnology (2023)
Megan D Schertzer, Andrew Stirn, Keren Isaev, Laura Pereira, Anjali Das, Claire Harbison, Stella H Park, Hans-Hermann Wessels, Neville E Sanjana, David A Knowles
Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox. bioRxiv : the preprint server for biology (2023)
John A Morris, Christina M Caragine, Zharko Daniloski, Júlia Domingo, Timothy Barry, Lu Lu, Kyrie Davis, Marcello Ziosi, Dafni A Glinos, Stephanie Hao, Eleni P Mimitou, Peter Smibert, Kathryn Roeder, Eugene Katsevich, Tuuli Lappalainen, Neville E Sanjana
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens. Science (New York, N.Y.) 380 (6646) (2023)
John A Morris, Christina M Caragine, Zharko Daniloski, Júlia Domingo, Timothy Barry, Lu Lu, Kyrie Davis, Marcello Ziosi, Dafni A Glinos, Stephanie Hao, Eleni P Mimitou, Peter Smibert, Kathryn Roeder, Eugene Katsevich, Tuuli Lappalainen, Neville E Sanjana
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens. Science (New York, N.Y.) 380 (6646) (2023)
Congyi Lu, Görkem Garipler, Chao Dai, Timothy Roush, Jose Salome-Correa, Alex Martin, Noa Liscovitch-Brauer, Esteban Orlando Mazzoni, Neville E Sanjana
Essential transcription factors for induced neuron differentiation. Nature communications 14 (1) (2023)
Congyi Lu, Görkem Garipler, Chao Dai, Timothy Roush, Jose Salome-Correa, Alex Martin, Noa Liscovitch-Brauer, Esteban Orlando Mazzoni, Neville E Sanjana
Essential transcription factors for induced neuron differentiation. Nature communications 14 (1) (2023)
Wei Wei, Mitchell Jon Geer, Xinyi Guo, Igor Dolgalev, Neville E Sanjana, Benjamin G Neel
Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition. The Journal of experimental medicine 220 (5) (2023)
Wei Wei, Mitchell Jon Geer, Xinyi Guo, Igor Dolgalev, Neville E Sanjana, Benjamin G Neel
Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition. The Journal of experimental medicine 220 (5) (2023)
John A Morris, Christina M Caragine, Zharko Daniloski, Júlia Domingo, Timothy Barry, Lu Lu, Kyrie Davis, Marcello Ziosi, Dafni A Glinos, Stephanie Hao, Eleni P Mimitou, Peter Smibert, Kathryn Roeder, Eugene Katsevich, Tuuli Lappalainen, Neville E Sanjana
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens. Science (New York, N.Y.) (2023)
Congyi Lu, Görkem Garipler, Chao Dai, Timothy Roush, Jose Salome-Correa, Alex Martin, Noa Liscovitch-Brauer, Esteban Orlando Mazzoni, Neville E Sanjana
Essential transcription factors for induced neuron differentiation. Nature communications 14 (1) (2023)
Wei Wei, Mitchell Jon Geer, Xinyi Guo, Igor Dolgalev, Neville E Sanjana, Benjamin G Neel
Genome-wide CRISPR/Cas9 screens reveal shared and cell-specific mechanisms of resistance to SHP2 inhibition. The Journal of experimental medicine 220 (5) (2023)
Alyna Katti, Bianca J Diaz, Christina M Caragine, Neville E Sanjana, Lukas E Dow
CRISPR in cancer biology and therapy. Nature reviews. Cancer 22 (5) (2022)
Mateusz Legut, Zoran Z Gajic, Maria Guarino, Zharko Daniloski, Jahan A Rahman, Xinhe Xue, Congyi Lu, Lu Lu, Eleni P Mimitou, Stephanie Hao, Teresa Davoli, Catherine Diefenbach, Peter Smibert, Neville E Sanjana
A genome-scale screen for synthetic drivers of T cell proliferation. Nature 603 (7902) (2022)
Zoran Z Gajic, Aditya Deshpande, Mateusz Legut, Marcin Imielinski, Neville E Sanjana
Recurrent somatic mutations as predictors of immunotherapy response. Nature communications 13 (1) (2022)
Zoran Z Gajic, Aditya Deshpande, Mateusz Legut, Marcin Imielinski, Neville E Sanjana
Publisher Correction: Recurrent somatic mutations as predictors of immunotherapy response. Nature communications 13 (1) (2022)
Neville E Sanjana
Voices of the new generation: open science is good for science (and for you). Nature reviews. Molecular cell biology 22 (11) (2021)
Noa Liscovitch-Brauer, Antonino Montalbano, Jiale Deng, Alejandro Méndez-Mancilla, Hans-Hermann Wessels, Nicholas G Moss, Chia-Yu Kung, Akash Sookdeo, Xinyi Guo, Evan Geller, Suma Jaini, Peter Smibert, Neville E Sanjana
Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens. Nature biotechnology 39 (10) (2021)
Angela Lek, Yuanfan Zhang, Keryn G Woodman, Shushu Huang, Alec M DeSimone, Justin Cohen, Vincent Ho, James Conner, Lillian Mead, Andrew Kodani, Anna Pakula, Neville E Sanjana, Oliver D King, Peter L Jones, Kathryn R Wagner, Monkol Lek, Louis M Kunkel
Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy. Science translational medicine 12 (536) (2021)
Zharko Daniloski, Tristan X Jordan, Juliana K Ilmain, Xinyi Guo, Gira Bhabha, Benjamin R tenOever, Neville E Sanjana
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types. eLife 10 (2021)
Sophie Zaaijer, Simon Cornelis Groen, Neville E Sanjana
Tracking cell lineages to improve research reproducibility. Nature biotechnology 39 (6) (2021)
Zharko Daniloski, Tristan X Jordan, Juliana K Ilmain, Xinyi Guo, Gira Bhabha, Benjamin R tenOever, Neville E Sanjana
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types. bioRxiv : the preprint server for biology (2020)
Hans-Hermann Wessels, Alejandro Méndez-Mancilla, Xinyi Guo, Mateusz Legut, Zharko Daniloski, Neville E Sanjana
Massively parallel Cas13 screens reveal principles for guide RNA design. Nature biotechnology 38 (6) (2020)
Eleni P Mimitou, Anthony Cheng, Antonino Montalbano, Stephanie Hao, Marlon Stoeckius, Mateusz Legut, Timothy Roush, Alberto Herrera, Efthymia Papalexi, Zhengqing Ouyang, Rahul Satija, Neville E Sanjana, Sergei B Koralov, Peter Smibert
Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells. Nature methods 16 (5) (2019)
Neville E Sanjana
A genome-wide net to catch and understand cancer. Science translational medicine 10 (453) (2019)
Joshua A Meier, Feng Zhang, Neville E Sanjana
GUIDES: sgRNA design for loss-of-function screens. Nature methods 14 (9) (2019)
Julia Joung, Silvana Konermann, Jonathan Samuel Gootenberg, Omar O Abudayyeh, Randall J Platt, Mark D Brigham, Neville E Sanjana, Feng Zhang
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening. Nature protocols 12 (4) (2017)