David E Stec (David Stec)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 37

Top Topics

Top Venues

Antioxidants (Basel, Switzerland)

Physiological genomics

This page only lists publications with an associated author ORCID identifier.

Publications

Olufunto O Badmus, Alexandre Alves da Silva, Xuan Li, Lucy C Taylor, Jennifer R Greer, Andrew R Wasson, Karis E McGowan, Parth R Patel, David E Stec
Cardiac lipotoxicity and fibrosis underlie impaired contractility in a mouse model of metabolic dysfunction-associated steatotic liver disease. FASEB bioAdvances 6 (5) (2024)
Olufunto O Badmus, Alexandre Alves da Silva, Xuan Li, Lucy C Taylor, Jennifer R Greer, Andrew R Wasson, Karis E McGowan, Parth R Patel, David E Stec
Cardiac lipotoxicity and fibrosis underlie impaired contractility in a mouse model of metabolic dysfunction-associated steatotic liver disease. FASEB bioAdvances 6 (5) (2024)
Zachary A Kipp, Genesee J Martinez, Evelyn A Bates, Agil B Maharramov, Robert M Flight, Hunter N B Moseley, Andrew J Morris, David E Stec, Terry D Hinds
Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content. Metabolites 13 (2) (2023)
Evelyn A Bates, Zachary A Kipp, Genesee J Martinez, Olufunto O Badmus, Mangala M Soundarapandian, Donald Foster, Mei Xu, Justin Fortune Creeden, Jennifer R Greer, Andrew J Morris, David E Stec, Terry D Hinds
Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease. Biomolecules 13 (2) (2023)
Brigitte E Martin, Erin B Taylor, Esinam M Attipoe, Wenjie Wu, David E Stec, Kurt C Showmaker, Michael R Garrett
Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice. Physiological genomics 55 (2) (2023)
Evelyn A Bates, Zachary A Kipp, Genesee J Martinez, Olufunto O Badmus, Mangala M Soundarapandian, Donald Foster, Mei Xu, Justin Fortune Creeden, Jennifer R Greer, Andrew J Morris, David E Stec, Terry D Hinds
Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease. Biomolecules 13 (2) (2023)
Brigitte E Martin, Erin B Taylor, Esinam M Attipoe, Wenjie Wu, David E Stec, Kurt C Showmaker, Michael R Garrett
Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice. Physiological genomics 55 (2) (2023)
Brigitte E Martin, Erin B Taylor, Esinam M Attipoe, Wenjie Wu, David E Stec, Kurt C Showmaker, Michael R Garrett
Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice. Physiological genomics 55 (2) (2023)
Zachary A Kipp, Genesee J Martinez, Evelyn A Bates, Agil B Maharramov, Robert M Flight, Hunter N B Moseley, Andrew J Morris, David E Stec, Terry D Hinds
Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content. Metabolites 13 (2) (2023)
Evelyn A Bates, Zachary A Kipp, Genesee J Martinez, Olufunto O Badmus, Mangala M Soundarapandian, Donald Foster, Mei Xu, Justin Fortune Creeden, Jennifer R Greer, Andrew J Morris, David E Stec, Terry D Hinds
Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease. Biomolecules 13 (2) (2023)
Evelyn A Bates, Zachary A Kipp, Genesee J Martinez, Olufunto O Badmus, Mangala M Soundarapandian, Donald Foster, Mei Xu, Justin Fortune Creeden, Jennifer R Greer, Andrew J Morris, David E Stec, Terry D Hinds
Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease. Biomolecules 13 (2) (2023)
Olufunto O Badmus, Terry D Hinds, David E Stec
Mechanisms Linking Metabolic-Associated Fatty Liver Disease (MAFLD) to Cardiovascular Disease. Current hypertension reports (2023)
Zachary A Kipp, Genesee J Martinez, Evelyn A Bates, Agil B Maharramov, Robert M Flight, Hunter N B Moseley, Andrew J Morris, David E Stec, Terry D Hinds
Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content. Metabolites 13 (2) (2023)
Brigitte E Martin, Erin B Taylor, Esinam M Attipoe, Wenjie Wu, David E Stec, Kurt C Showmaker, Michael R Garrett
Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice. Physiological genomics 55 (2) (2023)
Zachary A Kipp, Genesee J Martinez, Evelyn A Bates, Agil B Maharramov, Robert M Flight, Hunter N B Moseley, Andrew J Morris, David E Stec, Terry D Hinds
Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content. Metabolites 13 (2) (2023)
Zachary A Kipp, Genesee J Martinez, Evelyn A Bates, Agil B Maharramov, Robert M Flight, Hunter N B Moseley, Andrew J Morris, David E Stec, Terry D Hinds
Bilirubin Nanoparticle Treatment in Obese Mice Inhibits Hepatic Ceramide Production and Remodels Liver Fat Content. Metabolites 13 (2) (2023)
Olufunto O Badmus, Sarah A Hillhouse, Christopher D Anderson, Terry D Hinds, David E Stec
Molecular mechanisms of metabolic associated fatty liver disease (MAFLD): functional analysis of lipid metabolism pathways. Clinical science (London, England : 1979) 136 (18) (2022)
Yan Lu, David E Stec, Ruisheng Liu, Michael Ryan, Heather A Drummond
βENaC and ASIC2 associate in VSMCs to mediate pressure-induced constriction in the renal afferent arteriole. American journal of physiology. Renal physiology 322 (5) (2022)
David Travis Thomas, Nicholas R DelCimmuto, Kyle D Flack, David E Stec, Terry D Hinds
Reactive Oxygen Species (ROS) and Antioxidants as Immunomodulators in Exercise: Implications for Heme Oxygenase and Bilirubin. Antioxidants (Basel, Switzerland) 11 (2) (2022)
David E Stec, Claudio Tiribelli, Olufunto O Badmus, Terry D Hinds
Novel Function for Bilirubin as a Metabolic Signaling Molecule: Implications for Kidney Diseases. Kidney360 3 (5) (2022)
Terry D Hinds, Zachary A Kipp, Mei Xu, Frederique B Yiannikouris, Andrew J Morris, Donald F Stec, Walter Wahli, David E Stec
Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK-SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue. Cells 11 (1) (2021)
David E Stec, Nader G Abraham
Pharmacological and Clinical Significance of Heme Oxygenase-1. Antioxidants (Basel, Switzerland) 10 (6) (2021)
Terry D Hinds, Justin F Creeden, Darren M Gordon, Adam C Spegele, Steven L Britton, Lauren G Koch, David E Stec
Rats Genetically Selected for High Aerobic Exercise Capacity Have Elevated Plasma Bilirubin by Upregulation of Hepatic Biliverdin Reductase-A (BVRA) and Suppression of UGT1A1. Antioxidants (Basel, Switzerland) 9 (9) (2020)
Justin F Creeden, Darren M Gordon, David E Stec, Terry D Hinds
Bilirubin as a metabolic hormone: the physiological relevance of low levels. American journal of physiology. Endocrinology and metabolism 320 (2) (2020)
Marco Raffaele, Maria Licari, Sherif Amin, Ragin Alex, Hsin-Hsueh Shen, Shailendra Pratap Singh, Luca Vanella, Rita Rezzani, Francesca Bonomini, Stephen J Peterson, David E Stec, Nader G Abraham
Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice. International journal of molecular sciences 21 (15) (2020)
Darren M Gordon, Kari L Neifer, Abdul-Rizaq Ali Hamoud, Charles F Hawk, Andrea Nestor Kalinoski, Scott A Miruzzi, Michael P Morran, Samuel O Adeosun, Jeffrey G Sarver, Paul W Erhardt, Robert E McCullumsmith, David E Stec, Terry D Hinds
Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor α. The Journal of biological chemistry 295 (29) (2020)
Hsin Hsueh Shen, Stephen J Peterson, Lars Bellner, Abu Choudhary, Lior Levy, Leah Gancz, Ariel Sasson, Joseph Trainer, Rita Rezzani, Abraham Resnick, David E Stec, Nader G Abraham
Cold-Pressed Nigella Sativa Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice. Antioxidants (Basel, Switzerland) 9 (6) (2020)
Hsin-Hsueh Shen, Ragin Alex, Lars Bellner, Marco Raffaele, Maria Licari, Luca Vanella, David E Stec, Nader G Abraham
Milk thistle seed cold press oil attenuates markers of the metabolic syndrome in a mouse model of dietary-induced obesity. Journal of food biochemistry 44 (12) (2020)
David E Stec, Terry D Hinds
Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease. International journal of molecular sciences 21 (24) (2020)
Stephen J Peterson, Rochelle Rubinstein, Mouzam Faroqui, Adnan Raza, Imene Boumaza, Yilun Zhang, David E Stec, Nader G Abraham
Positive Effects of Heme Oxygenase Upregulation on Adiposity and Vascular Dysfunction: Gene Targeting vs. Pharmacologic Therapy. International journal of molecular sciences 20 (10) (2019)
David E Stec, Darren M Gordon, Jennifer A Hipp, Stephen Hong, Zachary L Mitchell, Natalia R Franco, J Walker Robison, Christopher D Anderson, Donald F Stec, Terry D Hinds
Loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity. American journal of physiology. Regulatory, integrative and comparative physiology 317 (5) (2019)
Heather A Drummond, Zachary L Mitchell, Nader G Abraham, David E Stec
Targeting Heme Oxygenase-1 in Cardiovascular and Kidney Disease. Antioxidants (Basel, Switzerland) 8 (6) (2019)
Darren M Gordon, Thomas M Blomquist, Scott A Miruzzi, Robert McCullumsmith, David E Stec, Terry D Hinds
RNA sequencing in human HepG2 hepatocytes reveals PPAR-α mediates transcriptome responsiveness of bilirubin. Physiological genomics 51 (6) (2019)
Kavita Bisht, Giacomo Canesin, Tasneem Cheytan, Mailin Li, Zsuzsanna Németh, Eva Csizmadia, Trent M Woodruff, David E Stec, Andrew C Bulmer, Leo Edmond Otterbein, Barbara Wegiel
Deletion of Biliverdin Reductase A in Myeloid Cells Promotes Chemokine Expression and Chemotaxis in Part via a Complement C5a--C5aR1 Pathway. Journal of immunology (Baltimore, Md. : 1950) 202 (10) (2019)
Samuel O Adeosun, Darren M Gordon, Mary Frances Weeks, Kyle H Moore, John E Hall, Terry D Hinds, David E Stec
Loss of biliverdin reductase-A promotes lipid accumulation and lipotoxicity in mouse proximal tubule cells. American journal of physiology. Renal physiology 315 (2) (2018)
Lauren Weaver, Abdul-Rizaq Hamoud, David E Stec, Terry D Hinds
Biliverdin reductase and bilirubin in hepatic disease. American journal of physiology. Gastrointestinal and liver physiology 314 (6) (2018)
Terry D Hinds, Katherine A Burns, Peter A Hosick, Lucien McBeth, Andrea Nestor-Kalinoski, Heather A Drummond, Abdulhadi A AlAmodi, Michael W Hankins, John P Vanden Heuvel, David E Stec
Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α. The Journal of biological chemistry 291 (48) (2016)