David F Claxton (David Claxton)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 30

Top Venues

Blood advances

Cancers

International journal of molecular sciences

Molecular cancer research : MCR

Penn State Milton S Hershey Medical Center

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Penn State Milton S Hershey Medical Center Jul 15 2000

United States

Director, Hematological Malignancies :: Penn State Cancer Institute

Publications

B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene Lee, Wisam A Fares, Satyam Patel, Arati Sharma, Aaron D Viny, Brian M Barth, Martin S Tallman, Myles Cabot, Francine E Garrett-Bakelman, Ross L Levine, Mark Kester, David J Feith, David F Claxton, Kevin A Janes, Thomas P Loughran
Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes. Blood advances 8 (5) (2024)
B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene S Lee, Wisam Fares, Satyam Patel, Arati Sharma, Aaron D Viny, Brian M Barth, Martin S Tallman, Myles C Cabot, Francine E Garrett-Bakelman, Ross L Levine, Mark Kester, David J Feith, David F Claxton, Kevin A Janes, Thomas P Loughran
Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes. Blood advances (2024)
B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene Lee, Wisam A Fares, Satyam Patel, Arati Sharma, Aaron D Viny, Brian M Barth, Martin S Tallman, Myles Cabot, Francine E Garrett-Bakelman, Ross L Levine, Mark Kester, David J Feith, David F Claxton, Kevin A Janes, Thomas P Loughran
Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes. Blood advances 8 (5) (2024)
B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene S Lee, Wisam Fares, Satyam Patel, Arati Sharma, Aaron D Viny, Brian M Barth, Martin S Tallman, Myles C Cabot, Francine E Garrett-Bakelman, Ross L Levine, Mark Kester, David J Feith, David F Claxton, Kevin A Janes, Thomas P Loughran
Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes. Blood advances (2024)
Seema G Naik, Kevin L Rakszawski, Hong Zheng, David F Claxton, Kentaro Minagawa, Shin Mineishi
Clofarabine Preconditioning followed by Allogeneic Transplant Using TBI and Post-Transplant Cyclophosphamide for Relapsed Refractory Leukemia. International journal of molecular sciences 25 (2) (2024)
Seema G Naik, Kevin L Rakszawski, Hong Zheng, David F Claxton, Kentaro Minagawa, Shin Mineishi
Clofarabine Preconditioning followed by Allogeneic Transplant Using TBI and Post-Transplant Cyclophosphamide for Relapsed Refractory Leukemia. International journal of molecular sciences 25 (2) (2024)
Seema G Naik, Kevin L Rakszawski, Hong Zheng, David F Claxton, Kentaro Minagawa, Shin Mineishi
Clofarabine Preconditioning followed by Allogeneic Transplant Using TBI and Post-Transplant Cyclophosphamide for Relapsed Refractory Leukemia. International journal of molecular sciences 25 (2) (2024)
B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene Lee, Wisam A Fares, Satyam Patel, Arati Sharma, Aaron D Viny, Brian M Barth, Martin S Tallman, Myles Cabot, Francine E Garrett-Bakelman, Ross L Levine, Mark Kester, David J Feith, David F Claxton, Kevin A Janes, Thomas P Loughran
Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes. Blood advances 8 (5) (2024)
B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene S Lee, Wisam Fares, Satyam Patel, Arati Sharma, Aaron D Viny, Brian M Barth, Martin S Tallman, Myles C Cabot, Francine E Garrett-Bakelman, Ross L Levine, Mark Kester, David J Feith, David F Claxton, Kevin A Janes, Thomas P Loughran
Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes. Blood advances (2024)
B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene Lee, Wisam A Fares, Satyam Patel, Arati Sharma, Aaron D Viny, Brian M Barth, Martin S Tallman, Myles Cabot, Francine E Garrett-Bakelman, Ross L Levine, Mark Kester, David J Feith, David F Claxton, Kevin A Janes, Thomas P Loughran
Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes. Blood advances 8 (5) (2024)
B Bishal Paudel, Su-Fern Tan, Todd E Fox, Johnson Ung, Upendarrao Golla, Jeremy J P Shaw, Wendy Dunton, Irene Lee, Wisam A Fares, Satyam Patel, Arati Sharma, Aaron D Viny, Brian M Barth, Martin S Tallman, Myles Cabot, Francine E Garrett-Bakelman, Ross L Levine, Mark Kester, David J Feith, David F Claxton, Kevin A Janes, Thomas P Loughran
Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes. Blood advances 8 (5) (2024)
Johnson Ung, Su-Fern Tan, Todd E Fox, Jeremy J P Shaw, Maansi Taori, Bethany J Horton, Upendarrao Golla, Arati Sharma, Zdzislaw M Szulc, Hong-Gang Wang, Charles E Chalfant, Myles C Cabot, David F Claxton, Thomas P Loughran, Thomas P Loughran
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Cancers 15 (24) (2023)
Johnson Ung, Su-Fern Tan, Todd E Fox, Jeremy J P Shaw, Maansi Taori, Bethany J Horton, Upendarrao Golla, Arati Sharma, Zdzislaw M Szulc, Hong-Gang Wang, Charles E Chalfant, Myles C Cabot, David F Claxton, Thomas P Loughran, Thomas P Loughran
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Cancers 15 (24) (2023)
Bei Jia, Chenchen Zhao, Kentaro Minagawa, Hiroko Shike, David F Claxton, W Christopher Ehmann, Witold B Rybka, Shin Mineishi, Ming Wang, Todd D Schell, K Sandeep Prabhu, Robert F Paulson, Yi Zhang, Leonard D Shultz, Hong Zheng
Acute Myeloid Leukemia Causes T Cell Exhaustion and Depletion in a Humanized Graft-versus-Leukemia Model. Journal of immunology (Baltimore, Md. : 1950) (2023)
Johnson Ung, Su-Fern Tan, Todd E Fox, Jeremy J P Shaw, Maansi Taori, Bethany J Horton, Upendarrao Golla, Arati Sharma, Zdzislaw M Szulc, Hong-Gang Wang, Charles E Chalfant, Myles C Cabot, David F Claxton, Thomas P Loughran, Thomas P Loughran
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Cancers 15 (24) (2023)
Johnson Ung, Su-Fern Tan, Todd E Fox, Jeremy J P Shaw, Maansi Taori, Bethany J Horton, Upendarrao Golla, Arati Sharma, Zdzislaw M Szulc, Hong-Gang Wang, Charles E Chalfant, Myles C Cabot, David F Claxton, Thomas P Loughran, Thomas P Loughran
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Cancers 15 (24) (2023)
Johnson Ung, Su-Fern Tan, Todd E Fox, Jeremy J P Shaw, Maansi Taori, Bethany J Horton, Upendarrao Golla, Arati Sharma, Zdzislaw M Szulc, Hong-Gang Wang, Charles E Chalfant, Myles C Cabot, David F Claxton, Thomas P Loughran, Thomas P Loughran
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Cancers 15 (24) (2023)
Guillermo Garcia Manero, Nikolai A Podoltsev, Megan K D Othus, John M Pagel, Jerald P Radich, Min Fang, David A Rizzieri, Guido Marcucci, Stephen A Strickland, Mark R Litzow, M Lynn Savoie, Bruno C Medeiros, Mikkael A Sekeres, Tara L Lin, Geoffrey L Uy, Bayard L Powell, Jonathan E Kolitz, Richard A Larson, Richard M Stone, David F Claxton, James Essell, Selina M Luger, Sanjay R Mohan, Anna B Moseley, Frederick R Appelbaum, Harry P Erba
A randomized phase III study of standard versus high-dose cytarabine with or without vorinostat for AML. Leukemia (2023)
Johnson Ung, Su-Fern Tan, Todd E Fox, Jeremy J P Shaw, Maansi Taori, Bethany J Horton, Upendarrao Golla, Arati Sharma, Zdzislaw M Szulc, Hong-Gang Wang, Charles E Chalfant, Myles C Cabot, David F Claxton, Thomas P Loughran, Thomas P Loughran
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. Cancers 15 (24) (2023)
David F Claxton
Beware clonal haematopoiesis following chronic lymphocytic leukaemia treatment. British journal of haematology 198 (1) (2022)
Nathaniel A Long, Upendarrao Golla, Arati Sharma, David F Claxton
Acute Myeloid Leukemia Stem Cells: Origin, Characteristics, and Clinical Implications. Stem cell reviews and reports 18 (4) (2022)
Christopher J Pizzola, Joseph Cioccio, Kevin L Rakszawski, Myles Nickolich, W Christopher Ehmann, Witold B Rybka, Baldeep Wirk, Seema G Naik, Hong Zheng, Brooke Silar, Hiroko Shike, Shouhao Zhou, Shin Mineishi, Kentaro Minagawa, David F Claxton
Non-myeloablative allogeneic stem cell transplant with fludarabine and reduced dose cyclophosphamide in acute myeloid leukemia for older adults with comorbidities. Bone marrow transplantation 57 (11) (2022)
Brynn Levy, Linda B Baughn, Yassmine M N Akkari, Scott Chartrand, Brandon LaBarge, David F Claxton, Patrick Alan Lennon, Claudia Cujar, Ravindra Kolhe, Kate Kroeger, Beth A Pitel, Nikhil Sahajpal, Malini Sathanoori, George Vlad, Lijun Zhang, Min Fang, Rashmi Kanagal-Shamana, James R Broach
Optical Genome Mapping in Acute Myeloid Leukemia: A Multicenter Evaluation. Blood advances (2022)
Alan F List, Zhuoxin Sun, Amit K Verma, John M Bennett, Rami S Komrokji, Kathy McGraw, Jaroslaw Maciejewski, Jessica K Altman, Puneet S Cheema, David F Claxton, Selina M Luger, Ryan J Mattison, Timothy R Wassenaar, Andrew S Artz, Charles A Schiffer, Mark R Litzow, Martin S Tallman
Lenalidomide-Epoetin Alfa Versus Lenalidomide Monotherapy in Myelodysplastic Syndromes Refractory to Recombinant Erythropoietin. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39 (9) (2021)
Hagop M Kantarjian, Kebede H Begna, Jessica K Altman, Stuart L Goldberg, Mikkael A Sekeres, Stephen A Strickland, Martha L Arellano, David F Claxton, Maria R Baer, Marc Gautier, Ellin Berman, Karen Seiter, Scott R Solomon, Gary J Schiller, Selina M Luger, Aleksandra Butrym, Gianluca Gaidano, Xavier G Thomas, Pau Montesinos, David A Rizzieri, Donald P Quick, Parameswaran Venugopal, Rakesh Gaur, Lori J Maness, Tapan Mahendra Kadia, Farhad Ravandi, Marc E Buyse, Judy H Chiao
Results of a randomized phase 3 study of oral sapacitabine in elderly patients with newly diagnosed acute myeloid leukemia (SEAMLESS). Cancer 127 (23) (2021)
Brian M Barth, Weiyuan Wang, Paul T Toran, Todd E Fox, Charyguly Annageldiyev, Regina M Ondrasik, Nicole R Keasey, Timothy J Brown, Viola G Devine, Emily C Sullivan, Andrea L Cote, Vasiliki Papakotsi, Su-Fern Tan, Sriram S Shanmugavelandy, Tye G Deering, David B Needle, Stephan T Stern, Junjia Zhu, Jason Liao, Aaron D Viny, David J Feith, Ross L Levine, Hong-Gang Wang, Thomas P Loughran, Arati Sharma, Mark Kester, David F Claxton
Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia. Blood advances 3 (17) (2020)
Jennifer M Pearson, Su-Fern Tan, Arati Sharma, Charyguly Annageldiyev, Todd E Fox, Jose Luis Abad, Gemma Fabrias, Dhimant Desai, Shantu Amin, Hong-Gang Wang, Myles C Cabot, David F Claxton, Mark Kester, Thomas P Loughran, Thomas P Loughran
Ceramide Analogue SACLAC Modulates Sphingolipid Levels and MCL-1 Splicing to Induce Apoptosis in Acute Myeloid Leukemia. Molecular cancer research : MCR 18 (3) (2019)
Bei Jia, Chenchen Zhao, Kevin L Rakszawski, David F Claxton, W Christopher Ehmann, Witold B Rybka, Shin Mineishi, Ming Wang, Hiroko Shike, Michael G Bayerl, Jeffrey M Sivik, Todd D Schell, Joseph J Drabick, Raymond J Hohl, Hong Zheng
Eomes+T-betlow CD8+ T Cells Are Functionally Impaired and Are Associated with Poor Clinical Outcome in Patients with Acute Myeloid Leukemia. Cancer research 79 (7) (2019)
Joseph Cioccio, David F Claxton
Therapy of acute myeloid leukemia: therapeutic targeting of tyrosine kinases. Expert opinion on investigational drugs 28 (4) (2019)
Kathleen M Kokolus, Jeremy S Haley, Emily J Koubek, Raghavendra Gowda, Saketh S Dinavahi, Arati Sharma, David F Claxton, Klaus F Helm, Joseph J Drabick, Gavin P Robertson, Jeffrey D Neighbors, Raymond J Hohl, Todd D Schell
Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity. Oncoimmunology 8 (2) (2018)

David F Claxton.css-eqlu8i{font-size:small;padding-left:4px;} (David Claxton)

Publication Activity (10 Years)

Top Topics

Top Venues

David F Claxton (David Claxton)