David Stegner

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 33

Top Topics

Tyrosine Kinase

High Fat Diet Induced

Middle Cerebral Artery

Top Venues

International journal of molecular sciences

Nature cardiovascular research

This page only lists publications with an associated author ORCID identifier.

Publications

Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Michael C Honigberg, Mustafa Yalcinkaya, Tetsushi Nakao, Ashley Pournamadri, Tong Xiao, Mohammad Ali Hajebrahimi, Lisa Wasner, David Stegner, Tobias Petzold, Pradeep Natarajan, Steffen Massberg, Alan R Tall, Christian Schulz, Nan Wang
Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk. Blood 143 (15) (2024)
Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Michael C Honigberg, Mustafa Yalcinkaya, Tetsushi Nakao, Ashley Pournamadri, Tong Xiao, Mohammad Ali Hajebrahimi, Lisa Wasner, David Stegner, Tobias Petzold, Pradeep Natarajan, Steffen Massberg, Alan R Tall, Christian Schulz, Nan Wang
Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk. Blood 143 (15) (2024)
Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Michael C Honigberg, Mustafa Yalcinkaya, Tetsushi Nakao, Ashley Pournamadri, Tong Xiao, Mohammad Ali Hajebrahimi, Lisa Wasner, David Stegner, Tobias Petzold, Pradeep Natarajan, Steffen Massberg, Alan R Tall, Christian Schulz, Nan Wang
Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk. Blood 143 (15) (2024)
Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Michael C Honigberg, Mustafa Yalcinkaya, Tetsushi Nakao, Ashley Pournamadri, Tong Xiao, Mohammad Ali Hajebrahimi, Lisa Wasner, David Stegner, Tobias Petzold, Pradeep Natarajan, Steffen Massberg, Alan R Tall, Christian Schulz, Nan Wang
Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk. Blood 143 (15) (2024)
Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Michael C Honigberg, Mustafa Yalcinkaya, Tetsushi Nakao, Ashley Pournamadri, Tong Xiao, Mohammad Ali Hajebrahimi, Lisa Wasner, David Stegner, Tobias Petzold, Pradeep Natarajan, Steffen Massberg, Alan R Tall, Christian Schulz, Nan Wang
Jak2V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross-talk. Blood (2023)
Nathan L Asquith, Estelle Carminita, Virginia Camacho, Antonio Rodriguez-Romera, David Stegner, Daniela Freire, Isabelle C Becker, Kellie R Machlus, Abdullah Khan, Joseph E Italiano
The bone marrow is the primary site of thrombopoiesis. Blood (2023)
Till Karwen, Katarzyna Kolczynska-Matysiak, Carina Gross, Mona C Löffler, Mike Friedrich, Angel Loza Valdes, Werner Schmitz, Magdalena Wit, Filip Dziaczkowski, Andrey E Belykh, Jonathan Trujillo-Viera, Rabih El-Merahbi, Carsten Deppermann, Sameena Nawaz, Benoit Hastoy, Agnieszka Demczuk, Manuela Erk, Mariusz Roman Wieckowski, Patrik Rorsman, Katrin G Heinze, David Stegner, Bernhard Nieswandt, Grzegorz Sumara
Platelet-derived lipids promote insulin secretion of pancreatic β cells. EMBO molecular medicine (2023)
Joanne C Clark, Eleyna M Martin, Luis A Morán, Ying Di, Xueqing Wang, Malou Zuidscherwoude, Helena C Brown, Deirdre M Kavanagh, Johan Hummert, Johannes Andreas Eble, Bernhard Nieswandt, David Stegner, Alice Y Pollitt, Dirk-Peter Herten, Michael G Tomlinson, Angel García, Stephen P Watson
Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists. Communications biology 6 (1) (2023)
Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Michael C Honigberg, Mustafa Yalcinkaya, Tetsushi Nakao, Ashley Pournamadri, Tong Xiao, Mohammad Ali Hajebrahimi, Lisa Wasner, David Stegner, Tobias Petzold, Pradeep Natarajan, Steffen Massberg, Alan R Tall, Christian Schulz, Nan Wang
Jak2V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross-talk. Blood (2023)
Wenli Liu, Joachim Pircher, Art Schuermans, Qurrat Ul Ain, Zhe Zhang, Michael C Honigberg, Mustafa Yalcinkaya, Tetsushi Nakao, Ashley Pournamadri, Tong Xiao, Mohammad Ali Hajebrahimi, Lisa Wasner, David Stegner, Tobias Petzold, Pradeep Natarajan, Steffen Massberg, Alan R Tall, Christian Schulz, Nan Wang
Jak2V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross-talk. Blood (2023)
David Stegner, Vanessa Göb, Viola Krenzlin, Sarah Beck, Katherina Hemmen, Michael K Schuhmann, Barbara F Schörg, Christian Hackenbroch, Frauke May, Philipp Burkard, Jürgen Pinnecker, Alma Zernecke, Peter Rosenberger, Andreas Greinacher, Bernd J Pichler, Katrin G Heinze, Guido Stoll, Bernhard Nieswandt
Foudroyant cerebral venous (sinus) thrombosis triggered through CLEC-2 and GPIIb/IIIa dependent platelet activation. Nature cardiovascular research 1 (2) (2022)
Isabelle C Becker, Zoltan Nagy, Georgi Manukjan, Melanie Haffner-Luntzer, Maximilian Englert, Tobias Heib, Timo Vögtle, Carina Gross, Richa Bharti, Sascha Dietrich, Kristina Mott, Johannes Heck, Sebastian Stegmaier, Anke Baranowsky, Thorsten Schinke, Nicolas Schlegel, Tobias Heckel, David Stegner, Irina Pleines, Anita Ignatius, Harald Schulze, Bernhard Nieswandt
G6b-B regulates an essential step in megakaryocyte maturation. Blood advances 6 (10) (2022)
Hannah S Heil, Max Aigner, Sophia Maier, Prateek Gupta, Luise M C Evers, Vanessa Göb, Charly Kusch, Mara Meub, Bernhard Nieswandt, David Stegner, Katrin G Heinze
Mapping densely packed αIIbβ3 receptors in murine blood platelets with expansion microscopy. Platelets 33 (6) (2022)
Zahra Maqsood, Joanne C Clark, Eleyna M Martin, Yam Fung Hilaire Cheung, Luis A Morán, Sean E T Watson, Jeremy A Pike, Ying Di, Natalie S Poulter, Alexandre Stephane Slater, Bodo M H Lange, Bernhard Nieswandt, Johannes Andreas Eble, Mike G Tomlinson, Dylan M Owen, David Stegner, Lloyd J Bridge, Christoph Wierling, Steve P Watson
Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins. PLoS computational biology 18 (11) (2022)
David Stegner, Vanessa Göb, Viola Krenzlin, Sarah Beck, Katherina Hemmen, Michael K Schuhmann, Barbara F Schörg, Christian Hackenbroch, Frauke May, Philipp Burkard, Jürgen Pinnecker, Alma Zernecke, Peter Rosenberger, Andreas Greinacher, Bernd J Pichler, Katrin G Heinze, Guido Stoll, Bernhard Nieswandt
Foudroyant cerebral venous (sinus) thrombosis triggered through CLEC-2 and GPIIb/IIIa dependent platelet activation. Nature cardiovascular research 1 (2) (2022)
David Stegner, Vanessa Göb, Viola Krenzlin, Sarah Beck, Katherina Hemmen, Michael K Schuhmann, Barbara F Schörg, Christian Hackenbroch, Frauke May, Philipp Burkard, Jürgen Pinnecker, Alma Zernecke, Peter Rosenberger, Andreas Greinacher, Bernd J Pichler, Katrin G Heinze, Guido Stoll, Bernhard Nieswandt
Foudroyant cerebral venous (sinus) thrombosis triggered through CLEC-2 and GPIIb/IIIa dependent platelet activation. Nature cardiovascular research 1 (2) (2022)
Stefano Navarro, Andreas Starke, Johan W M Heemskerk, Marijke J E Kuijpers, David Stegner, Bernhard Nieswandt
Targeting of a Conserved Epitope in Mouse and Human GPVI Differently Affects Receptor Function. International journal of molecular sciences 23 (15) (2022)
Helena C Brown, Sarah Beck, Stefano Navarro, Ying Di, Eva M Soriano Jerez, Jana Kaczmarzyk, Steven G Thomas, Valbona Mirakaj, Stephen P Watson, Bernhard Nieswandt, David Stegner
Antibody-mediated depletion of human CLEC-2 in a novel humanised mouse model. Blood advances (2022)
Raluca A I Neagoe, Elizabeth E Gardiner, David Stegner, Bernhard Nieswandt, Stephen P Watson, Natalie S Poulter
Rac Inhibition Causes Impaired GPVI Signalling in Human Platelets through GPVI Shedding and Reduction in PLCγ2 Phosphorylation. International journal of molecular sciences 23 (7) (2022)
Gina Perrella, Samantha J Montague, Helena C Brown, Lourdes Garcia Quintanilla, Alexandre Slater, David Stegner, Mark Thomas, Johan W M Heemskerk, Steve P Watson
Role of Tyrosine Kinase Syk in Thrombus Stabilisation at High Shear. International journal of molecular sciences 23 (1) (2022)
Michael Bieber, Michael K Schuhmann, Maximilian Bellut, David Stegner, Katrin G Heinze, Mirko Pham, Bernhard Nieswandt, Guido Stoll
Blockade of Platelet Glycoprotein Ibα Augments Neuroprotection in Orai2-Deficient Mice during Middle Cerebral Artery Occlusion. International journal of molecular sciences 23 (16) (2022)
Stefano Navarro, David Stegner, Bernhard Nieswandt, Johan W M Heemskerk, Marijke J E Kuijpers
Temporal Roles of Platelet and Coagulation Pathways in Collagen- and Tissue Factor-Induced Thrombus Formation. International journal of molecular sciences 23 (1) (2021)
Nicole Wagner, Kristina Mott, Berin Upcin, David Stegner, Harald Schulze, Süleyman Ergün
CXCL12-Abundant Reticular (CAR) Cells Direct Megakaryocyte Protrusions across the Bone Marrow Sinusoid Wall. Cells 10 (4) (2021)
Tobias Heib, Carina Gross, Martha-Lena Müller, David Stegner, Irina Pleines
Isolation of murine bone marrow by centrifugation or flushing for the analysis of hematopoietic cells - a comparative study. Platelets 32 (5) (2020)
David Stegner, Katrin G Heinze
Intravital imaging of megakaryocytes. Platelets 31 (5) (2020)
Mohsen Malehmir, Dominik Pfister, Suchira Gallage, Marta Szydlowska, Donato Inverso, Elena Kotsiliti, Valentina Leone, Moritz Peiseler, Bas G J Surewaard, Dominik Rath, Adnan Ali, Monika Julia Wolf, Hannah Drescher, Marc E Healy, Daniel Dauch, Daniela Kroy, Oliver Krenkel, Marlene Kohlhepp, Thomas Engleitner, Alexander Olkus, Tjeerd Sijmonsma, Julia Volz, Carsten Deppermann, David Stegner, Patrick Michael Helbling, Cesar Nombela-Arrieta, Anahita Rafiei, Martina Hinterleitner, Marcel Rall, Florian Baku, Oliver Borst, Caroline L Wilson, Jack Leslie, Tracy O'Connor, Christopher J Weston, David H Adams, Lozan Sheriff, Ana Teijeiro, Marco Prinz, Ruzhica Bogeska, Natasha Anstee, Malte Niklas Bongers, Mike Notohamiprodjo, Tobias Geisler, Dominic J Withers, Jerry Ware, Derek A Mann, Hellmut G Augustin, Alexandros Vegiopoulos, Michael D Milsom, Adam J Rose, Patricia F Lalor, Josep M Llovet, Roser Pinyol, Frank Tacke, Roland Rad, Matthias S Matter, Nabil Djouder, Paul Kubes, Percy A Knolle, Kristian Unger, Lars Zender, Bernhard Nieswandt, Meinrad Paul Gawaz, Achim Weber, Mathias F Heikenwälder
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer. Nature medicine 25 (4) (2019)
Markus Spindler, Judith M M van Eeuwijk, Yvonne Schurr, Paquita Nurden, Bernhard Nieswandt, David Stegner, Annegret Reinhold, Markus Bender
ADAP deficiency impairs megakaryocyte polarization with ectopic proplatelet release and causes microthrombocytopenia. Blood 132 (6) (2018)
Harald Schulze, David Stegner
Imaging platelet biogenesis in vivo. Research and practice in thrombosis and haemostasis 2 (3) (2018)
David Stegner, Judith M M vanEeuwijk, Oğuzhan Angay, Maximilian G Gorelashvili, Daniela Semeniak, Jürgen Pinnecker, Patrick Schmithausen, Imke Meyer, Mike Friedrich, Sebastian Dütting, Christian Brede, Andreas Beilhack, Harald Schulze, Bernhard Nieswandt, Katrin G Heinze
Thrombopoiesis is spatially regulated by the bone marrow vasculature. Nature communications 8 (1) (2017)
Carsten Deppermann, Peter Kraft, Julia Volz, Michael K Schuhmann, Sarah Beck, Karen Wolf, David Stegner, Guido Stoll, Bernhard Nieswandt
Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice. Blood 129 (12) (2017)
Sebastian Dütting, Frederique Gaits-Iacovoni, David Stegner, Michael Popp, Adrien Antkowiak, Judith M M van Eeuwijk, Paquita Nurden, Simon Stritt, Tobias Heib, Katja Aurbach, Oguzhan Angay, Deya Cherpokova, Niels Heinz, Ayesha A Baig, Maximilian G Gorelashvili, Frank Gerner, Katrin G Heinze, Jerry Ware, Georg Krohne, Zaverio M Ruggeri, Alan T Nurden, Harald Schulze, Ute Modlich, Irina Pleines, Cord Brakebusch, Bernhard Nieswandt
A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis. Nature communications 8 (2017)
Elizabeth J Haining, Deya Cherpokova, Karen Wolf, Isabelle C Becker, Sarah Beck, Johannes A Eble, David Stegner, Stephen P Watson, Bernhard Nieswandt
CLEC-2 contributes to hemostasis independently of classical hemITAM signaling in mice. Blood 130 (20) (2017)
Sebastian Drube, Randy Grimlowski, Carsten Deppermann, Julia Fröbel, Florian Kraft, Nico Andreas, David Stegner, Jan Dudeck, Franziska Weber, Mandy Rödiger, Christiane Göpfert, Julia Drube, Daniela Reich, Bernhard Nieswandt, Anne Dudeck, Thomas Kamradt
The Neurobeachin-like 2 Protein Regulates Mast Cell Homeostasis. Journal of immunology (Baltimore, Md. : 1950) 199 (8) (2017)