Derek K O'Flaherty

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 24

Top Venues

Journal of the American Chemical Society

Chembiochem : a European journal of chemical biology

Angewandte Chemie (International ed. in English)

Current protocols

Massachusetts General Hospital

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts General Hospital Apr 01 2016

United States

Postdoctoral Research Fellow :: Molecular Biology

Publications

Jagandeep S Saraya, Derek K O'Flaherty
A Facile and General Tandem Oligonucleotide Synthesis Methodology for DNA and RNA. Chembiochem : a European journal of chemical biology 25 (6) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
James D Robinson, Scott R Sammons, Derek K O'Flaherty
Preparation of 2-Aminoimidazole-Activated Substrates for the Study of Nonenzymatic Genome Replication. Current protocols 4 (8) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society (2024)
Jagandeep S Saraya, Derek K O'Flaherty
A Facile and General Tandem Oligonucleotide Synthesis Methodology for DNA and RNA. Chembiochem : a European journal of chemical biology 25 (6) (2024)
Jagandeep S Saraya, Derek K O'Flaherty
A facile and general tandem oligonucleotide synthesis methodology for DNA and RNA. Chembiochem : a European journal of chemical biology (2024)
Jagandeep S Saraya, Derek K O'Flaherty
A Facile and General Tandem Oligonucleotide Synthesis Methodology for DNA and RNA. Chembiochem : a European journal of chemical biology 25 (6) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
Mikołaj J Janicki, Corinna L Kufner, Zoe R Todd, Seohyun Chris Kim, Derek K O'Flaherty, Jack W Szostak, Jiřı Šponer, Robert W Góra, Dimitar D Sasselov, Rafał Szabla
Ribose Alters the Photochemical Properties of the Nucleobase in Thionated Nucleosides. The journal of physical chemistry letters 12 (28) (2021)
Roger Rubio-Sánchez, Derek K O'Flaherty, Anna Wang, Francesca Coscia, Gianluca Petris, Lorenzo Di Michele, Pietro Cicuta, Claudia Bonfio
Thermally Driven Membrane Phase Transitions Enable Content Reshuffling in Primitive Cells. Journal of the American Chemical Society 143 (40) (2021)
Seohyun Chris Kim, Derek K O'Flaherty, Constantin Giurgiu, Lijun Zhou, Jack W Szostak
The Emergence of RNA from the Heterogeneous Products of Prebiotic Nucleotide Synthesis. Journal of the American Chemical Society 143 (9) (2021)
Lijun Zhou, Derek K O'Flaherty, Jack W Szostak
Assembly of a Ribozyme Ligase from Short Oligomers by Nonenzymatic Ligation. Journal of the American Chemical Society 142 (37) (2020)
Lijun Zhou, Derek K O'Flaherty, Jack W Szostak
Template-Directed Copying of RNA by Non-enzymatic Ligation. Angewandte Chemie (International ed. in English) 59 (36) (2020)
Seohyun Chris Kim, Lijun Zhou, Wen Zhang, Derek K O'Flaherty, Valeria Rondo-Brovetto, Jack W Szostak
A Model for the Emergence of RNA from a Prebiotically Plausible Mixture of Ribonucleotides, Arabinonucleotides, and 2'-Deoxynucleotides. Journal of the American Chemical Society 142 (5) (2020)
Derek K O'Flaherty, Lijun Zhou, Jack W Szostak
Nonenzymatic Template-Directed Synthesis of Mixed-Sequence 3'-NP-DNA up to 25 Nucleotides Long Inside Model Protocells. Journal of the American Chemical Society 141 (26) (2019)
Tom H Wright, Constantin Giurgiu, Wen Zhang, Aleksandar Radakovic, Derek K O'Flaherty, Lijun Zhou, Jack W Szostak
Prebiotically Plausible "Patching" of RNA Backbone Cleavage through a 3'-5' Pyrophosphate Linkage. Journal of the American Chemical Society 141 (45) (2019)
Lijun Zhou, Seohyun Chris Kim, Katherine H Ho, Derek K O'Flaherty, Constantin Giurgiu, Tom H Wright, Jack W Szostak
Non-enzymatic primer extension with strand displacement. eLife 8 (2019)
Seohyun Chris Kim, Derek K O'Flaherty, Lijun Zhou, Victor S Lelyveld, Jack W Szostak
Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA. Proceedings of the National Academy of Sciences of the United States of America 115 (52) (2018)
Derek K O'Flaherty, Neha P Kamat, Fatima N Mirza, Li Li, Noam Prywes, Jack W Szostak
Copying of Mixed-Sequence RNA Templates inside Model Protocells. Journal of the American Chemical Society 140 (15) (2018)
Constantin Giurgiu, Tom H Wright, Derek K O'Flaherty, Jack W Szostak
A Fluorescent G-Quadruplex Sensor for Chemical RNA Copying. Angewandte Chemie (International ed. in English) 57 (31) (2018)
Derek K O'Flaherty, Christopher J Wilds
AGT Activity Towards Intrastrand Crosslinked DNA is Modulated by the Alkylene Linker. Chembiochem : a European journal of chemical biology 18 (23) (2017)

Derek K O'Flaherty.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Derek K O'Flaherty