Jack W Szostak

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 99

Top Topics

Molecularly Imprinted

Top Venues

Journal of the American Chemical Society

Proceedings of the National Academy of Sciences of the United States of America

Nucleic acids research

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Zachary R Cohen, Dian Ding, Lijun Zhou, Saurja DasGupta, Sebastian Haas, Kimberly P Sinclair, Zoe R Todd, Roy A Black, Jack W Szostak, David C Catling
Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life. PNAS nexus 3 (3) (2024)
Aleksandar Radakovic, Anna Lewicka, Marco Todisco, Harry R M Aitken, Zoe Weiss, Shannon Kim, Abdullah Bannan, Joseph A Piccirilli, Jack W Szostak
A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Ziyuan Fang, Lydia T Pazienza, Jian Zhang, Chun Pong Tam, Jack W Szostak
Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. Journal of the American Chemical Society 146 (15) (2024)
Marco Todisco, Dian Ding, Jack W Szostak
Transient states during the annealing of mismatched and bulged oligonucleotides. Nucleic acids research 52 (5) (2024)
Aman Agrawal, Aleksandar Radakovic, Anusha Vonteddu, Syed Rizvi, Vivian N Huynh, Jack F Douglas, Matthew V Tirrell, Alamgir Karim, Jack W Szostak
Did the exposure of coacervate droplets to rain make them the first stable protocells? Science advances 10 (34) (2024)
Aman Agrawal, Aleksandar Radakovic, Anusha Vonteddu, Syed Rizvi, Vivian N Huynh, Jack F Douglas, Matthew V Tirrell, Alamgir Karim, Jack W Szostak
Did the exposure of coacervate droplets to rain make them the first stable protocells? Science advances 10 (34) (2024)
Marco Todisco, Aleksandar Radakovic, Jack W Szostak
RNA Complexes with Nicks and Gaps: Thermodynamic and Kinetic Effects of Coaxial Stacking and Dangling Ends. Journal of the American Chemical Society 146 (26) (2024)
Xiwen Jia, Ziyuan Fang, Seohyun Chris Kim, Dian Ding, Lijun Zhou, Jack W Szostak
Diaminopurine in Nonenzymatic RNA Template Copying. Journal of the American Chemical Society 146 (23) (2024)
Aleksandar Radakovic, Anna Lewicka, Marco Todisco, Harry R M Aitken, Zoe Weiss, Shannon Kim, Abdullah Bannan, Joseph A Piccirilli, Jack W Szostak
Structure-guided aminoacylation and assembly of chimeric RNAs. bioRxiv : the preprint server for biology (2024)
Xiwen Jia, Ziyuan Fang, Seohyun Chris Kim, Dian Ding, Lijun Zhou, Jack W Szostak
Diaminopurine in Nonenzymatic RNA Template Copying. Journal of the American Chemical Society 146 (23) (2024)
Marco Todisco, Dian Ding, Jack W Szostak
Transient states during the annealing of mismatched and bulged oligonucleotides. Nucleic acids research (2024)
Ziyuan Fang, Lydia T Pazienza, Jian Zhang, Chun Pong Tam, Jack W Szostak
Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. Journal of the American Chemical Society 146 (15) (2024)
Marco Todisco, Aleksandar Radakovic, Jack W Szostak
RNA Complexes with Nicks and Gaps: Thermodynamic and Kinetic Effects of Coaxial Stacking and Dangling Ends. Journal of the American Chemical Society 146 (26) (2024)
Marco Todisco, Dian Ding, Jack W Szostak
Transient states during the annealing of mismatched and bulged oligonucleotides. Nucleic acids research 52 (5) (2024)
Zachary R Cohen, Dian Ding, Lijun Zhou, Saurja DasGupta, Sebastian Haas, Kimberly P Sinclair, Zoe R Todd, Roy A Black, Jack W Szostak, David C Catling
Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life. PNAS nexus 3 (3) (2024)
Xiwen Jia, Stephanie J Zhang, Lijun Zhou, Jack W Szostak
Constraints on the emergence of RNA through non-templated primer extension with mixtures of potentially prebiotic nucleotides. Nucleic acids research 52 (10) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
Xiwen Jia, Stephanie J Zhang, Lijun Zhou, Jack W Szostak
Constraints on the emergence of RNA through non-templated primer extension with mixtures of potentially prebiotic nucleotides. Nucleic acids research 52 (10) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
Marco Todisco, Aleksandar Radakovic, Jack W Szostak
RNA Complexes with Nicks and Gaps: Thermodynamic and Kinetic Effects of Coaxial Stacking and Dangling Ends. Journal of the American Chemical Society (2024)
Aleksandar Radakovic, Anna Lewicka, Marco Todisco, Harry R M Aitken, Zoe Weiss, Shannon Kim, Abdullah Bannan, Joseph A Piccirilli, Jack W Szostak
A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Ziyuan Fang, Lydia T Pazienza, Jian Zhang, Chun Pong Tam, Jack W Szostak
Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. Journal of the American Chemical Society (2024)
Saurja DasGupta, Zoe Weiss, Collin Nisler, Jack W Szostak
Evolution of the substrate specificity of an RNA ligase ribozyme from phosphorimidazole to triphosphate activation. Proceedings of the National Academy of Sciences of the United States of America 121 (38) (2024)
Zachary R Cohen, Dian Ding, Lijun Zhou, Saurja DasGupta, Sebastian Haas, Kimberly P Sinclair, Zoe R Todd, Roy A Black, Jack W Szostak, David C Catling
Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life. PNAS nexus 3 (3) (2024)
Marco Todisco, Aleksandar Radakovic, Jack W Szostak
RNA Complexes with Nicks and Gaps: Thermodynamic and Kinetic Effects of Coaxial Stacking and Dangling Ends. Journal of the American Chemical Society 146 (26) (2024)
Xiwen Jia, Ziyuan Fang, Seohyun Chris Kim, Dian Ding, Lijun Zhou, Jack W Szostak
Diaminopurine in Nonenzymatic RNA Template Copying. Journal of the American Chemical Society (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
Xiwen Jia, Ziyuan Fang, Seohyun Chris Kim, Dian Ding, Lijun Zhou, Jack W Szostak
Diaminopurine in Nonenzymatic RNA Template Copying. Journal of the American Chemical Society 146 (23) (2024)
Ziyuan Fang, Lydia T Pazienza, Jian Zhang, Chun Pong Tam, Jack W Szostak
Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. Journal of the American Chemical Society 146 (15) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society (2024)
Ziyuan Fang, Lydia T Pazienza, Jian Zhang, Chun Pong Tam, Jack W Szostak
Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. Journal of the American Chemical Society 146 (15) (2024)
Xiwen Jia, Ziyuan Fang, Seohyun Chris Kim, Dian Ding, Lijun Zhou, Jack W Szostak
Diaminopurine in Nonenzymatic RNA Template Copying. Journal of the American Chemical Society 146 (23) (2024)
Marco Todisco, Dian Ding, Jack W Szostak
Transient states during the annealing of mismatched and bulged oligonucleotides. Nucleic acids research 52 (5) (2024)
Aleksandar Radakovic, Anna Lewicka, Marco Todisco, Harry R M Aitken, Zoe Weiss, Shannon Kim, Abdullah Bannan, Joseph A Piccirilli, Jack W Szostak
A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Xiwen Jia, Stephanie J Zhang, Lijun Zhou, Jack W Szostak
Constraints on the emergence of RNA through non-templated primer extension with mixtures of potentially prebiotic nucleotides. Nucleic acids research (2024)
Ziyuan Fang, Lydia T Pazienza, Jian Zhang, Chun Pong Tam, Jack W Szostak
Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. Journal of the American Chemical Society 146 (15) (2024)
Zachary R Cohen, Dian Ding, Lijun Zhou, Saurja DasGupta, Sebastian Haas, Kimberly P Sinclair, Zoe R Todd, Roy A Black, Jack W Szostak, David C Catling
Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life. PNAS nexus 3 (3) (2024)
Xiwen Jia, Stephanie J Zhang, Lijun Zhou, Jack W Szostak
Constraints on the emergence of RNA through non-templated primer extension with mixtures of potentially prebiotic nucleotides. Nucleic acids research 52 (10) (2024)
Dian Ding, Ziyuan Fang, Seohyun Chris Kim, Derek K O'Flaherty, Xiwen Jia, Talbot B Stone, Lijun Zhou, Jack W Szostak
Unusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying. Journal of the American Chemical Society 146 (6) (2024)
Dian Ding, Lijun Zhou, Shriyaa Mittal, Jack W Szostak
Experimental Tests of the Virtual Circular Genome Model for Nonenzymatic RNA Replication. Journal of the American Chemical Society (2023)
Victor S Lelyveld, Ziyuan Fang, Jack W Szostak
Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science (New York, N.Y.) 382 (6669) (2023)
Brennan Ashwood, Michael S Jones, Aleksandar Radakovic, Smayan Khanna, Yumin Lee, Joseph R Sachleben, Jack W Szostak, Andrew L Ferguson, Andrei Tokmakoff
Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs. bioRxiv : the preprint server for biology (2023)
Ziyan Fan, Yaam Deckel, Lauren A Lowe, Daniel W K Loo, Tetsuya Yomo, Jack W Szostak, Collin Nisler, Anna Wang
Lipid Exchange Promotes Fusion of Model Protocells. Small methods (2023)
Sarah J Crucilla, Dian Ding, Gabriella G Lozano, Jack W Szostak, Dimitar D Sasselov, Corinna L Kufner
UV-driven self-repair of cyclobutane pyrimidine dimers in RNA. Chemical communications (Cambridge, England) (2023)
Stephanie J Zhang, Lauren A Lowe, Palapuravan Anees, Yamuna Krishnan, Thomas G Fai, Jack W Szostak, Anna Wang
Passive endocytosis in model protocells. bioRxiv : the preprint server for biology (2023)
Stephanie J Zhang, Lauren A Lowe, Palapuravan Anees, Yamuna Krishnan, Thomas G Fai, Jack W Szostak, Anna Wang
Passive endocytosis in model protocells. Proceedings of the National Academy of Sciences of the United States of America 120 (24) (2023)
Saurja DasGupta, Stephanie Zhang, Jack W Szostak
Molecular Crowding Facilitates Ribozyme-Catalyzed RNA Assembly. ACS central science 9 (8) (2023)
Brennan Ashwood, Michael S Jones, Aleksandar Radakovic, Smayan Khanna, Yumin Lee, Joseph R Sachleben, Jack W Szostak, Andrew L Ferguson, Andrei Tokmakoff
Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs. bioRxiv : the preprint server for biology (2023)
Harry R M Aitken, Tom H Wright, Aleksandar Radakovic, Jack W Szostak
Small-Molecule Organocatalysis Facilitates In Situ Nucleotide Activation and RNA Copying. Journal of the American Chemical Society (2023)
Stephanie J Zhang, Lauren A Lowe, Palapuravan Anees, Yamuna Krishnan, Thomas G Fai, Jack W Szostak, Anna Wang
Passive endocytosis in model protocells. bioRxiv : the preprint server for biology (2023)
Stephanie J Zhang, Lauren A Lowe, Palapuravan Anees, Yamuna Krishnan, Thomas G Fai, Jack W Szostak, Anna Wang
Passive endocytosis in model protocells. bioRxiv : the preprint server for biology (2023)
Ö Duhan Toparlak, Lorenzo Sebastianelli, Veronica Egas Ortuno, Megha Karki, Yanfeng Xing, Jack W Szostak, Ramanarayanan Krishnamurthy, Sheref S Mansy
Cyclophospholipids Enable a Protocellular Life Cycle. ACS nano (2023)
Corinna L Kufner, Sarah J Crucilla, Dian Ding, Petr Stadlbauer, Jiřı Šponer, Jack W Szostak, Dimitar D Sasselov, Rafał Szabla
Photoinduced charge separation and DNA self-repair depend on sequence directionality and stacking pattern. Chemical science 15 (6) (2023)
Brennan Ashwood, Michael S Jones, Aleksandar Radakovic, Smayan Khanna, Yumin Lee, Joseph R Sachleben, Jack W Szostak, Andrew L Ferguson, Andrei Tokmakoff
Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs. bioRxiv : the preprint server for biology (2023)
Dian Ding, Stephanie J Zhang, Jack W Szostak
Enhanced nonenzymatic RNA copying with in-situ activation of short oligonucleotides. Nucleic acids research (2023)
Brennan Ashwood, Michael S Jones, Aleksandar Radakovic, Smayan Khanna, Yumin Lee, Joseph R Sachleben, Jack W Szostak, Andrew L Ferguson, Andrei Tokmakoff
Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs. bioRxiv : the preprint server for biology (2023)
Corinna L Kufner, Sarah J Crucilla, Dian Ding, Petr Stadlbauer, Jiřı Šponer, Jack W Szostak, Dimitar D Sasselov, Rafał Szabla
Photoinduced charge separation and DNA self-repair depend on sequence directionality and stacking pattern. Chemical science 15 (6) (2023)
Aleksandar Radakovic, Saurja DasGupta, Tom H Wright, Harry R M Aitken, Jack W Szostak
Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides. Proceedings of the National Academy of Sciences of the United States of America 119 (7) (2022)
Stephanie J Zhang, Daniel Duzdevich, Dian Ding, Jack W Szostak
Freeze-thaw cycles enable a prebiotically plausible and continuous pathway from nucleotide activation to nonenzymatic RNA copying. Proceedings of the National Academy of Sciences of the United States of America 119 (17) (2022)
Long-Fei Wu, Ziwei Liu, Samuel J Roberts, Meng Su, Jack W Szostak, John D Sutherland
Template-Free Assembly of Functional RNAs by Loop-Closing Ligation. Journal of the American Chemical Society 144 (30) (2022)
Kyle R Strom, Jack W Szostak
Folding and Duplex Formation in Sequence-Defined Aniline Benzaldehyde Oligoarylacetylenes. Journal of the American Chemical Society 144 (40) (2022)
Mikołaj J Janicki, Corinna L Kufner, Zoe R Todd, Seohyun Chris Kim, Derek K O'Flaherty, Jack W Szostak, Jiřı Šponer, Robert W Góra, Dimitar D Sasselov, Rafał Szabla
Ribose Alters the Photochemical Properties of the Nucleobase in Thionated Nucleosides. The journal of physical chemistry letters 12 (28) (2021)
Zoe R Todd, Jack W Szostak, Dimitar D Sasselov
Shielding from UV Photodamage: Implications for Surficial Origins of Life Chemistry on the Early Earth. ACS earth & space chemistry 5 (2) (2021)
Seohyun Chris Kim, Derek K O'Flaherty, Constantin Giurgiu, Lijun Zhou, Jack W Szostak
The Emergence of RNA from the Heterogeneous Products of Prebiotic Nucleotide Synthesis. Journal of the American Chemical Society 143 (9) (2021)
Aleksandar Radakovic, Tom H Wright, Victor S Lelyveld, Jack W Szostak
A Potential Role for Aminoacylation in Primordial RNA Copying Chemistry. Biochemistry 60 (6) (2021)
Constantin Giurgiu, Ziyuan Fang, Harry R M Aitken, Seohyun Chris Kim, Lydia Pazienza, Shriyaa Mittal, Jack W Szostak
Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis. Angewandte Chemie (International ed. in English) 60 (42) (2021)
Lijun Zhou, Derek K O'Flaherty, Jack W Szostak
Assembly of a Ribozyme Ligase from Short Oligomers by Nonenzymatic Ligation. Journal of the American Chemical Society 142 (37) (2020)
Lijun Zhou, Derek K O'Flaherty, Jack W Szostak
Template-Directed Copying of RNA by Non-enzymatic Ligation. Angewandte Chemie (International ed. in English) 59 (36) (2020)
Travis Walton, Saurja DasGupta, Daniel Duzdevich, Seung Soo Oh, Jack W Szostak
In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole-activated substrates. Proceedings of the National Academy of Sciences of the United States of America 117 (11) (2020)
Victor S Lelyveld, Wen Zhang, Jack W Szostak
Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)
James T Kindt, Jack W Szostak, Anna Wang
Bulk Self-Assembly of Giant, Unilamellar Vesicles. ACS nano 14 (11) (2020)
Seohyun Chris Kim, Lijun Zhou, Wen Zhang, Derek K O'Flaherty, Valeria Rondo-Brovetto, Jack W Szostak
A Model for the Emergence of RNA from a Prebiotically Plausible Mixture of Ribonucleotides, Arabinonucleotides, and 2'-Deoxynucleotides. Journal of the American Chemical Society 142 (5) (2020)
Stephanie J Zhang, Daniel Duzdevich, Jack W Szostak
Potentially Prebiotic Activation Chemistry Compatible with Nonenzymatic RNA Copying. Journal of the American Chemical Society 142 (35) (2020)
Kyle R Strom, Jack W Szostak
Solid-Phase Synthesis of Sequence-Defined Informational Oligomers. The Journal of organic chemistry 85 (21) (2020)
Fabio Chizzolini, Luiz F M Passalacqua, Mona Oumais, Armine I Dingilian, Jack W Szostak, Andrej Lupták
Large Phenotypic Enhancement of Structured Random RNA Pools. Journal of the American Chemical Society 142 (4) (2020)
Lijun Zhou, Dian Ding, Jack W Szostak
The virtual circular genome model for primordial RNA replication. RNA (New York, N.Y.) 27 (1) (2020)
Kyle R Strom, Jack W Szostak, Noam Prywes
Transfer of Sequence Information and Replication of Diimine Duplexes. The Journal of organic chemistry 84 (7) (2019)
Derek K O'Flaherty, Lijun Zhou, Jack W Szostak
Nonenzymatic Template-Directed Synthesis of Mixed-Sequence 3'-NP-DNA up to 25 Nucleotides Long Inside Model Protocells. Journal of the American Chemical Society 141 (26) (2019)
Tom H Wright, Constantin Giurgiu, Wen Zhang, Aleksandar Radakovic, Derek K O'Flaherty, Lijun Zhou, Jack W Szostak
Prebiotically Plausible "Patching" of RNA Backbone Cleavage through a 3'-5' Pyrophosphate Linkage. Journal of the American Chemical Society 141 (45) (2019)
Weicheng Zhang, Ayan Pal, Alonso Ricardo, Jack W Szostak
Template-Directed Nonenzymatic Primer Extension Using 2-Methylimidazole-Activated Morpholino Derivatives of Guanosine and Cytidine. Journal of the American Chemical Society 141 (30) (2019)
Travis Walton, Wen Zhang, Li Li, Chun Pong Tam, Jack W Szostak
The Mechanism of Nonenzymatic Template Copying with Imidazole-Activated Nucleotides. Angewandte Chemie (International ed. in English) 58 (32) (2019)
Yuka Matsushita-Ishiodori, Martin M Hanczyc, Anna Wang, Jack W Szostak, Tetsuya Yomo
Using Imaging Flow Cytometry to Quantify and Optimize Giant Vesicle Production by Water-in-oil Emulsion Transfer Methods. Langmuir : the ACS journal of surfaces and colloids 35 (6) (2019)
Lijun Zhou, Seohyun Chris Kim, Katherine H Ho, Derek K O'Flaherty, Constantin Giurgiu, Tom H Wright, Jack W Szostak
Non-enzymatic primer extension with strand displacement. eLife 8 (2019)
Wen Zhang, Travis Walton, Li Li, Jack W Szostak
Crystallographic observation of nonenzymatic RNA primer extension. eLife 7 (2018)
Lin Jin, Aaron E Engelhart, Weicheng Zhang, Katarzyna P Adamala, Jack W Szostak
Catalysis of Template-Directed Nonenzymatic RNA Copying by Iron(II). Journal of the American Chemical Society 140 (44) (2018)
Seohyun Chris Kim, Derek K O'Flaherty, Lijun Zhou, Victor S Lelyveld, Jack W Szostak
Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA. Proceedings of the National Academy of Sciences of the United States of America 115 (52) (2018)
Ayan Pal, Rajat S Das, Weicheng Zhang, Megan Lang, Larry W McLaughlin, Jack W Szostak
Effect of terminal 3'-hydroxymethyl modification of an RNA primer on nonenzymatic primer extension. Chemical communications (Cambridge, England) 52 (80) (2018)
Derek K O'Flaherty, Neha P Kamat, Fatima N Mirza, Li Li, Noam Prywes, Jack W Szostak
Copying of Mixed-Sequence RNA Templates inside Model Protocells. Journal of the American Chemical Society 140 (15) (2018)
Constantin Giurgiu, Tom H Wright, Derek K O'Flaherty, Jack W Szostak
A Fluorescent G-Quadruplex Sensor for Chemical RNA Copying. Angewandte Chemie (International ed. in English) 57 (31) (2018)
Chun Pong Tam, Lijun Zhou, Albert C Fahrenbach, Wen Zhang, Travis Walton, Jack W Szostak
Synthesis of a Nonhydrolyzable Nucleotide Phosphoroimidazolide Analogue That Catalyzes Nonenzymatic RNA Primer Extension. Journal of the American Chemical Society 140 (2) (2018)
Wen Zhang, Chun Pong Tam, Lijun Zhou, Seung Soo Oh, Jiawei Wang, Jack W Szostak
Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide. Journal of the American Chemical Society 140 (8) (2018)
Travis Walton, Lydia Pazienza, Jack W Szostak
Template-Directed Catalysis of a Multistep Reaction Pathway for Nonenzymatic RNA Primer Extension. Biochemistry 58 (6) (2018)
Albert C Fahrenbach, Constantin Giurgiu, Chun Pong Tam, Li Li, Yayoi Hongo, Masashi Aono, Jack W Szostak
Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation. Journal of the American Chemical Society 139 (26) (2017)
Travis Walton, Jack W Szostak
A Kinetic Model of Nonenzymatic RNA Polymerization by Cytidine-5'-phosphoro-2-aminoimidazolide. Biochemistry 56 (43) (2017)
Li Li, Noam Prywes, Chun Pong Tam, Derek K O'Flaherty, Victor S Lelyveld, Enver Cagri Izgu, Ayan Pal, Jack W Szostak
Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides. Journal of the American Chemical Society 139 (5) (2017)
Constantin Giurgiu, Li Li, Derek K O'Flaherty, Chun Pong Tam, Jack W Szostak
A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension. Journal of the American Chemical Society 139 (46) (2017)
Elizabeth Ransey, Anders Björkbom, Victor S Lelyveld, Przemysław Biecek, Lorena Pantano, Jack W Szostak, Piotr Sliz
Comparative analysis of LIN28-RNA binding sites identified at single nucleotide resolution. RNA biology 14 (12) (2017)
Noam Prywes, J Craig Blain, Francesca Del Frate, Jack W Szostak
Nonenzymatic copying of RNA templates containing all four letters is catalyzed by activated oligonucleotides. eLife 5 (2016)