Derek P Claxton

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 13

Top Venues

PNAS nexus

The Journal of biological chemistry

Proceedings of the National Academy of Sciences of the United States of America

Science advances

Vanderbilt University

Vanderbilt University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Vanderbilt University

United States

Research Assistant Professor :: Molecular Physiology and Biophysics

Oregon Health & Science University

United States

Postdoctoral Fellow :: Vollum Institute

Education History

Vanderbilt University

United States

PHD :: Molecular Physiology and Biophysics

University of Alabama in Huntsville

United States

BSC :: Chemistry

Publications

Matt Sinclair, Richard A Stein, Jonathan H Sheehan, Emily M Hawes, Richard K P Benninger, Emad Tajkhorshid, Derek P Claxton
Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model. PNAS nexus 3 (2) (2024)
Matt Sinclair, Richard A Stein, Jonathan H Sheehan, Emily M Hawes, Richard K P Benninger, Emad Tajkhorshid, Derek P Claxton
Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model. PNAS nexus 3 (2) (2024)
Matt Sinclair, Richard A Stein, Jonathan H Sheehan, Emily M Hawes, Richard K P Benninger, Emad Tajkhorshid, Derek P Claxton
Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model. PNAS nexus 3 (2) (2024)
Matt Sinclair, Richard A Stein, Jonathan H Sheehan, Emily M Hawes, Richard K P Benninger, Emad Tajkhorshid, Derek P Claxton
Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model. PNAS nexus 3 (2) (2024)
Matt Sinclair, Richard A Stein, Jonathan H Sheehan, Emily M Hawes, Richard K P Benninger, Emad Tajkhorshid, Derek P Claxton
Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model. PNAS nexus 3 (2) (2024)
Matt Sinclair, Richard A Stein, Jonathan H Sheehan, Emily M Hawes, Richard M O'Brien, Emad Tajkhorshid, Derek P Claxton
Molecular mechanisms of functional impairment for active site mutations in glucose-6-phosphatase catalytic subunit 1 linked to glycogen storage disease type 1a. bioRxiv : the preprint server for biology (2023)
Steven Castellano, Derek P Claxton, Emel Ficici, Tsukasa Kusakizako, Robyn Stix, Wenchang Zhou, Osamu Nureki, Hassane S Mchaourab, José D Faraldo-Gómez
Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na+ in ion-coupled drug efflux. The Journal of biological chemistry (2021)
Bing Han, Jason C Porta, Jessica L Hanks, Yelena Peskova, Elad M Binshtein, Kelly Dryden, Derek P Claxton, Hassane S Mchaourab, Erkan Karakas, Melanie D Ohi, Anne K Kenworthy
Structure and assembly of CAV1 8S complexes revealed by single particle electron microscopy. Science advances 6 (49) (2020)
Kevin L Jagessar, Derek P Claxton, Richard A Stein, Hassane S Mchaourab
Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter. Proceedings of the National Academy of Sciences of the United States of America 117 (9) (2020)
Kevin L Jagessar, Hassane S Mchaourab, Derek P Claxton
The N-terminal domain of an archaeal multidrug and toxin extrusion (MATE) transporter mediates proton coupling required for prokaryotic drug resistance. The Journal of biological chemistry 294 (34) (2019)
Swastik Phulera, Hongtao Zhu, Jie Yu, Derek P Claxton, Nate Yoder, Craig Yoshioka, Eric Gouaux
Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2S tri-heteromeric GABAA receptor in complex with GABA. eLife 7 (2018)
Derek P Claxton, Kevin L Jagessar, P Ryan Steed, Richard A Stein, Hassane S Mchaourab
Sodium and proton coupling in the conformational cycle of a MATE antiporter from Vibrio cholerae. Proceedings of the National Academy of Sciences of the United States of America 115 (27) (2018)
Derek P Claxton, Eric Gouaux
Expression and purification of a functional heteromeric GABAA receptor for structural studies. PloS one 13 (7) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Derek P Claxton