Eric Gouaux

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 45

Top Venues

Nature

Proceedings of the National Academy of Sciences of the United States of America

PloS one

eLife

Oregon Health and Science University

Harvard University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Oregon Health and Science University

United States

Jennifer and Bernard Lacroute Term Chair in Neuroscience Research

Oregon Health and Science University

United States

Senior Scientist :: Vollum Institute

Howard Hughes Medical Institute

United States

Investigator

Columbia University

United States

Professor :: Biochem and Mol Biophys

Columbia University

United States

Director :: Program in Molecular Biophysics

Columbia University

United States

Assoc. Prof. :: Biochem and Mol Biophys

Columbia University

United States

Asst. Prof. :: Biochem and Mol Biophys.

University of Chicago

United States

Asst. Professor :: Biochem and Mol Biol

Education History

Harvard University

United States

PHD :: Chemistry

Publications

Dushyant Kumar Srivastava, Vikas Navratna, Dilip K Tosh, Audrey Chinn, Md Fulbabu Sk, Emad Tajkhorshid, Kenneth A Jacobson, Eric Gouaux
Structure of the human dopamine transporter and mechanisms of inhibition. Nature (2024)
Sarah Clark, Hanbin Jeong, Rich Posert, April Goehring, Eric Gouaux
The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction. Proceedings of the National Academy of Sciences of the United States of America 121 (8) (2024)
Dushyant Kumar Srivastava, Vikas Navratna, Dilip K Tosh, Audrey Chinn, Md Fulbabu Sk, Emad Tajkhorshid, Kenneth A Jacobson, Eric Gouaux
Structure of the human dopamine transporter and mechanisms of inhibition. Nature 632 (8025) (2024)
Dushyant Kumar Srivastava, Vikas Navratna, Dilip K Tosh, Audrey Chinn, Md Fulbabu Sk, Emad Tajkhorshid, Kenneth A Jacobson, Eric Gouaux
Structure of the human dopamine transporter and mechanisms of inhibition. Nature 632 (8025) (2024)
Sarah Clark, Hanbin Jeong, Rich Posert, April Goehring, Eric Gouaux
The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction. Proceedings of the National Academy of Sciences of the United States of America 121 (8) (2024)
Dushyant Kumar Srivastava, Vikas Navratna, Dilip K Tosh, Audrey Chinn, Md Fulbabu Sk, Emad Tajkhorshid, Kenneth A Jacobson, Eric Gouaux
Structure of the human dopamine transporter and mechanisms of inhibition. Nature 632 (8025) (2024)
Sarah Clark, Hanbin Jeong, Rich Posert, April Goehring, Eric Gouaux
The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction. Proceedings of the National Academy of Sciences of the United States of America 121 (8) (2024)
Sarah Clark, Hanbin Jeong, Rich Posert, April Goehring, Eric Gouaux
The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction. Proceedings of the National Academy of Sciences of the United States of America 121 (8) (2024)
Sarah Clark, Hanbin Jeong, Rich Posert, April Goehring, Eric Gouaux
The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction. Proceedings of the National Academy of Sciences of the United States of America 121 (8) (2024)
Dushyant Kumar Srivastava, Vikas Navratna, Dilip K Tosh, Audrey Chinn, Md Fulbabu Sk, Emad Tajkhorshid, Kenneth A Jacobson, Eric Gouaux
Structure of the human dopamine transporter and mechanisms of inhibition. Nature 632 (8025) (2024)
Dushyant Kumar Srivastava, Vikas Navratna, Dilip K Tosh, Audrey Chinn, Md Fulbabu Sk, Emad Tajkhorshid, Kenneth A Jacobson, Eric Gouaux
Structure of the human dopamine transporter and mechanisms of inhibition. Nature 632 (8025) (2024)
Dushyant Kumar Srivastava, Vikas Navratna, Dilip K Tosh, Audrey Chinn, Md Fulbabu Sk, Emad Tajkhorshid, Kenneth A Jacobson, Eric Gouaux
Structure of the human dopamine transporter and mechanisms of inhibition. Nature (2024)
Sarah Clark, Hanbin Jeong, Rich Posert, April Goehring, Eric Gouaux
The structure of the Caenorhabditis elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction. Proceedings of the National Academy of Sciences of the United States of America 121 (8) (2024)
Prashant Rao, Eric Gouaux
Purification and biochemical analysis of native AMPA receptors from three different mammalian species. PloS one 18 (3) (2023)
Sarah Clark, Jaba Mitra, Johannes Elferich, April Goehring, Jingpeng Ge, Taekjip Ha, Eric Gouaux
Single molecule studies of the native hair cell mechanosensory transduction complex. bioRxiv : the preprint server for biology (2023)
Chang Sun, Hongtao Zhu, Sarah Clark, Eric Gouaux
Regulated assembly and neurosteroid modulation constrain GABA A receptor pharmacology in vivo . bioRxiv : the preprint server for biology (2023)
Sarah Clark, Jaba Mitra, Johannes Elferich, April Goehring, Jingpeng Ge, Taekjip Ha, Eric Gouaux
Single molecule studies of the native hair cell mechanosensory transduction complex. bioRxiv : the preprint server for biology (2023)
Chang Sun, Hongtao Zhu, Sarah Clark, Eric Gouaux
Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology. Nature (2023)
Sarah Clark, Jaba Mitra, Johannes Elferich, April Goehring, Jingpeng Ge, Taekjip Ha, Eric Gouaux
Single molecule studies of the native hair cell mechanosensory transduction complex. bioRxiv : the preprint server for biology (2023)
Prashant Rao, Eric Gouaux
Purification and biochemical analysis of native AMPA receptors from three different mammalian species. PloS one 18 (3) (2023)
Prashant Rao, Eric Gouaux
Purification and biochemical analysis of native AMPA receptors from three different mammalian species. PloS one 18 (3) (2023)
Sarah Clark, Hanbin Jeong, Richard Posert, April Goehring, Eric Gouaux
Structure of C. elegans TMC-2 complex suggests roles of lipid-mediated subunit contacts in mechanosensory transduction. bioRxiv : the preprint server for biology (2023)
Prashant Rao, Eric Gouaux
Purification and biochemical analysis of native AMPA receptors from three different mammalian species. PloS one 18 (3) (2023)
Sarah Clark, Hanbin Jeong, April Goehring, Yunsik Kang, Eric Gouaux
Large-scale growth of C. elegans and isolation of membrane protein complexes. Nature protocols (2023)
Dongxue Yang, Zhiyu Zhao, Emad Tajkhorshid, Eric Gouaux
Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants. Proceedings of the National Academy of Sciences of the United States of America 120 (29) (2023)
Sarah Clark, Jaba Mitra, Johannes Elferich, April Goehring, Jingpeng Ge, Taekjip Ha, Eric Gouaux
Single molecule studies of the native hair cell mechanosensory transduction complex. bioRxiv : the preprint server for biology (2023)
Josip Ivica, Hongtao Zhu, Remigijus Lape, Eric Gouaux, Lucia G Sivilotti
Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor. eLife 11 (2022)
Hanbin Jeong, Sarah Clark, April Goehring, Sepehr Dehghani-Ghahnaviyeh, Ali Rasouli, Emad Tajkhorshid, Eric Gouaux
Structures of the TMC-1 complex illuminate mechanosensory transduction. Nature 610 (7933) (2022)
Prerana Gogoi, Momoko Shiozaki, Eric Gouaux
Isolation, cryo-laser scanning confocal microscope imaging and cryo-FIB milling of mouse glutamatergic synaptosomes. PloS one 17 (8) (2022)
Jie Yu, Prashant Rao, Sarah Clark, Jaba Mitra, Taekjip Ha, Eric Gouaux
Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. Nature 594 (7863) (2021)
Johannes Elferich, Sarah Clark, Jingpeng Ge, April Goehring, Aya Matsui, Eric Gouaux
Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography. eLife 10 (2021)
Dongxue Yang, Eric Gouaux
Illumination of serotonin transporter mechanism and role of the allosteric site. Science advances 7 (49) (2021)
Per Plenge, Dongxue Yang, Kristine Walloe Salomon, Louise Laursen, Iris E Kalenderoglou, Amy Hauck Newman, Eric Gouaux, Jonathan A Coleman, Claus J Løland
The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. Nature communications 12 (1) (2021)
Hongtao Zhu, Eric Gouaux
Architecture and assembly mechanism of native glycine receptors. Nature 599 (7885) (2021)
Jonathan A Coleman, Vikas Navratna, Daniele Antermite, Dongxue Yang, James A Bull, Eric Gouaux
Chemical and structural investigation of the paroxetine-human serotonin transporter complex. eLife 9 (2020)
Brian E Jones, Kenneth R Tovar, April Goehring, Farzad Jalali-Yazdi, Nana J Okada, Eric Gouaux, Gary L Westbrook
Autoimmune receptor encephalitis in mice induced by active immunization with conformationally stabilized holoreceptors. Science translational medicine 11 (500) (2020)
Nate Yoder, Eric Gouaux
The His-Gly motif of acid-sensing ion channels resides in a reentrant 'loop' implicated in gating and ion selectivity. eLife 9 (2020)
Nicholas G Campbell, Aparna Shekar, Jenny I Aguilar, Dungeng Peng, Vikas Navratna, Dongxue Yang, Alexander N Morley, Amanda M Duran, Greta Galli, Brian O'Grady, Ramnarayan Ramachandran, James S Sutcliffe, Harald H Sitte, Kevin Erreger, Jens Meiler, Thomas Stockner, Leon M Bellan, Heinrich J G Matthies, Eric Gouaux, Hassane S Mchaourab, Aurelio Galli
Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3. Proceedings of the National Academy of Sciences of the United States of America 116 (9) (2019)
Yan Zhao, Shanshuang Chen, Adam C Swensen, Wei-Jun Qian, Eric Gouaux
Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM. Science (New York, N.Y.) 364 (6438) (2019)
Jingpeng Ge, Johannes Elferich, April Goehring, Huaging Zhao, Peter W Schuck, Eric Gouaux
Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5. eLife 7 (2018)
Nate Yoder, Eric Gouaux
Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography. PloS one 13 (8) (2018)
Swastik Phulera, Hongtao Zhu, Jie Yu, Derek P Claxton, Nate Yoder, Craig Yoshioka, Eric Gouaux
Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2S tri-heteromeric GABAA receptor in complex with GABA. eLife 7 (2018)
Vikas Navratna, Dilip K Tosh, Kenneth A Jacobson, Eric Gouaux
Thermostabilization and purification of the human dopamine transporter (hDAT) in an inhibitor and allosteric ligand bound conformation. PloS one 13 (7) (2018)
Derek P Claxton, Eric Gouaux
Expression and purification of a functional heteromeric GABAA receptor for structural studies. PloS one 13 (7) (2018)
Wei Lü, Juan Du, April Goehring, Eric Gouaux
Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation. Science (New York, N.Y.) 355 (6331) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Eric Gouaux