Des R Richardson

Publication Activity (10 Years)

Years Active: 2023-2024
Publications (10 Years): 15

Top Topics

Molecular Dynamics Simulations

Structure Activity Relationship

Hydrogen Peroxide

Top Venues

Journal of medicinal chemistry

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

Busra Kaya, Mahan Gholam Azad, Mediha Suleymanoglu, Jeffery R Harmer, Tharushi P Wijesinghe, Vera Richardson, Xiao Zhao, Paul V Bernhardt, Mahendiran Dharmasivam, Des R Richardson
Isosteric Replacement of Sulfur to Selenium in a Thiosemicarbazone: Promotion of Zn(II) Complex Dissociation and Transmetalation to Augment Anticancer Efficacy. Journal of medicinal chemistry (2024)
Busra Kaya, Henry Smith, Yanbing Chen, Mahan Gholam Azad, Tiffany M Russell, Vera Richardson, Paul V Bernhardt, Mahendiran Dharmasivam, Des R Richardson
Targeting lysosomes by design: novel N -acridine thiosemicarbazones that enable direct detection of intracellular drug localization and overcome P-glycoprotein (Pgp)-mediated resistance. Chemical science (2024)
Busra Kaya, Mahan Gholam Azad, Mediha Suleymanoglu, Jeffery R Harmer, Tharushi P Wijesinghe, Vera Richardson, Xiao Zhao, Paul V Bernhardt, Mahendiran Dharmasivam, Des R Richardson
Isosteric Replacement of Sulfur to Selenium in a Thiosemicarbazone: Promotion of Zn(II) Complex Dissociation and Transmetalation to Augment Anticancer Efficacy. Journal of medicinal chemistry 67 (14) (2024)
Tharushi P Wijesinghe, Busra Kaya, Miguel A Gonzálvez, Jeffery R Harmer, Mahan Gholam Azad, Paul V Bernhardt, Mahendiran Dharmasivam, Des R Richardson
Correction to "Steric Blockade of Oxy-Myoglobin Oxidation by Thiosemicarbazones: Structure-Activity Relationships of the Novel PPP4pT Series''. Journal of medicinal chemistry (2024)
Busra Kaya, Mahan Gholam Azad, Mediha Suleymanoglu, Jeffery R Harmer, Tharushi P Wijesinghe, Vera Richardson, Xiao Zhao, Paul V Bernhardt, Mahendiran Dharmasivam, Des R Richardson
Isosteric Replacement of Sulfur to Selenium in a Thiosemicarbazone: Promotion of Zn(II) Complex Dissociation and Transmetalation to Augment Anticancer Efficacy. Journal of medicinal chemistry 67 (14) (2024)
Busra Kaya, Henry Smith, Yanbing Chen, Mahan Gholam Azad, Tiffany M Russell, Vera Richardson, Paul V Bernhardt, Mahendiran Dharmasivam, Des R Richardson
Targeting lysosomes by design: novel N -acridine thiosemicarbazones that enable direct detection of intracellular drug localization and overcome P-glycoprotein (Pgp)-mediated resistance. Chemical science (2024)
Busra Kaya, Mahan Gholam Azad, Mediha Suleymanoglu, Jeffery R Harmer, Tharushi P Wijesinghe, Vera Richardson, Xiao Zhao, Paul V Bernhardt, Mahendiran Dharmasivam, Des R Richardson
Isosteric Replacement of Sulfur to Selenium in a Thiosemicarbazone: Promotion of Zn(II) Complex Dissociation and Transmetalation to Augment Anticancer Efficacy. Journal of medicinal chemistry 67 (14) (2024)
Tharushi P Wijesinghe, Busra Kaya, Miguel A Gonzálvez, Jeffery R Harmer, Mahan Gholam Azad, Paul V Bernhardt, Mahendiran Dharmasivam, Des R Richardson
Correction to "Steric Blockade of Oxy-Myoglobin Oxidation by Thiosemicarbazones: Structure-Activity Relationships of the Novel PPP4pT Series''. Journal of medicinal chemistry 67 (8) (2024)
Mahendiran Dharmasivam, Busra Kaya, Tharushi P Wijesinghe, Vera Richardson, Jeffrey R Harmer, Miguel A Gonzalvez, William Lewis, Mahan Gholam Azad, Paul V Bernhardt, Des R Richardson
Differential transmetallation of complexes of the anti-cancer thiosemicarbazone, Dp4e4mT: effects on anti-proliferative efficacy, redox activity, oxy-myoglobin and oxy-hemoglobin oxidation. Chemical science 15 (3) (2023)
Mahendiran Dharmasivam, Busra Kaya, Tharushi Wijesinghe, Mahan Gholam Azad, Miguel A Gonzálvez, Mohammad Hussaini, Jason Chekmarev, Paul V Bernhardt, Des R Richardson
Designing Tailored Thiosemicarbazones with Bespoke Properties: The Styrene Moiety Imparts Potent Activity, Inhibits Heme Center Oxidation, and Results in a Novel "Stealth Zinc(II) Complex". Journal of medicinal chemistry 66 (2) (2023)
Mahendiran Dharmasivam, Busra Kaya, Tharushi Wijesinghe, Mahan Gholam Azad, Miguel A Gonzálvez, Mohammad Hussaini, Jason Chekmarev, Paul V Bernhardt, Des R Richardson
Designing Tailored Thiosemicarbazones with Bespoke Properties: The Styrene Moiety Imparts Potent Activity, Inhibits Heme Center Oxidation, and Results in a Novel "Stealth Zinc(II) Complex". Journal of medicinal chemistry 66 (2) (2023)
Mahendiran Dharmasivam, Busra Kaya, Tharushi P Wijesinghe, Vera Richardson, Jeffrey R Harmer, Miguel A Gonzalvez, William Lewis, Mahan Gholam Azad, Paul V Bernhardt, Des R Richardson
Differential transmetallation of complexes of the anti-cancer thiosemicarbazone, Dp4e4mT: effects on anti-proliferative efficacy, redox activity, oxy-myoglobin and oxy-hemoglobin oxidation. Chemical science 15 (3) (2023)
Mahendiran Dharmasivam, Busra Kaya, Tharushi Wijesinghe, Mahan Gholam Azad, Miguel A Gonzálvez, Mohammad Hussaini, Jason Chekmarev, Paul V Bernhardt, Des R Richardson
Designing Tailored Thiosemicarbazones with Bespoke Properties: The Styrene Moiety Imparts Potent Activity, Inhibits Heme Center Oxidation, and Results in a Novel "Stealth Zinc(II) Complex". Journal of medicinal chemistry (2023)
Mahendiran Dharmasivam, Busra Kaya, Tharushi Wijesinghe, Mahan Gholam Azad, Miguel A Gonzálvez, Mohammad Hussaini, Jason Chekmarev, Paul V Bernhardt, Des R Richardson
Designing Tailored Thiosemicarbazones with Bespoke Properties: The Styrene Moiety Imparts Potent Activity, Inhibits Heme Center Oxidation, and Results in a Novel "Stealth Zinc(II) Complex". Journal of medicinal chemistry 66 (2) (2023)
Tharushi P Wijesinghe, Busra Kaya, Miguel A Gonzálvez, Jeffery R Harmer, Mahan Gholam Azad, Paul V Bernhardt, Mahendiran Dharmasivam, Des R Richardson
Steric Blockade of Oxy-Myoglobin Oxidation by Thiosemicarbazones: Structure-Activity Relationships of the Novel PPP4pT Series. Journal of medicinal chemistry (2023)