Dieter Petit

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 4

Top Topics

Cystic Fibrosis

Mild Cognitive Impairment

Top Venues

The EMBO journal

Molecular psychiatry

KU Leuven

This page only lists publications with an associated author ORCID identifier.

Affiliation History

KU Leuven Sep 15o 2015

Belgium

PhD student :: Center for brain and disease

Publications

Matthias Koch, Enzlein Thomas, Shu-Yu Chen, Dieter Petit, Sam Lismont, Martin Zacharias, Carsten Hopf, Chávez-Gutiérrez Lucía
APP substrate ectodomain defines amyloid-β peptide length by restraining γ-secretase processivity and facilitating product release. The EMBO journal (2023)
Dieter Petit, Sara Gutiérrez Fernández, Zoltowska Katarzyna Marta, Enzlein Thomas, Natalie S Ryan, Antoinette O'Connor, Maria Szaruga, Elizabeth Hill, Rik Vandenberghe, Nick C Fox, Chávez-Gutiérrez Lucía
Aβ profiles generated by Alzheimer's disease causing PSEN1 variants determine the pathogenicity of the mutation and predict age at disease onset. Molecular psychiatry 27 (6) (2022)
Dieter Petit, Manuel Hitzenberger, Matthias Koch, Sam Lismont, Zoltowska Katarzyna Marta, Enzlein Thomas, Carsten Hopf, Martin Zacharias, Chávez-Gutiérrez Lucía
Enzyme-substrate interface targeting by imidazole-based γ-secretase modulators activates γ-secretase and stabilizes its interaction with APP. The EMBO journal 41 (21) (2022)
Dieter Petit, Manuel Hitzenberger, Sam Lismont, Zoltowska Katarzyna Marta, Natalie S Ryan, Marc Mercken, Francois Bischoff, Martin Zacharias, Chávez-Gutiérrez Lucía
Extracellular interface between APP and Nicastrin regulates Aβ length and response to γ-secretase modulators. The EMBO journal 38 (12) (2019)