Chávez-Gutiérrez Lucía (Lucía Chávez-Gutiérrez)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 19

Top Topics

Blood Brain Barrier

Pluripotent Stem Cells

Cognitive Decline

Top Venues

Analytical chemistry

The EMBO journal

EMBO molecular medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Enzlein Thomas, Tammaryn Lashley, Denis Abu Sammour, Carsten Hopf, Chávez-Gutiérrez Lucía
Integrative Single-Plaque Analysis Reveals Signature Aβ and Lipid Profiles in the Alzheimer's Brain. Analytical chemistry 96 (24) (2024)
Zoltowska Katarzyna Marta, Utpal Das, Sam Lismont, Thomas Enzlein, Maesako Masato, Mei C Q Houser, Maria Luisa Franco, Burcu Özcan, Gomes Moreira Diana, Dmitry Karachentsev, Ann Becker, Carsten Hopf, Marçal Vilar, Berezovska Oksana, William Mobley, Chávez-Gutiérrez Lucía
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling. eLife 12 (2024)
Zoltowska Katarzyna Marta, Utpal Das, Sam Lismont, Thomas Enzlein, Maesako Masato, Mei C Q Houser, Maria Luisa Franco, Burcu Özcan, Gomes Moreira Diana, Dmitry Karachentsev, Ann Becker, Carsten Hopf, Marçal Vilar, Berezovska Oksana, William Mobley, Chávez-Gutiérrez Lucía
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling. eLife 12 (2024)
Enzlein Thomas, Tammaryn Lashley, Denis Abu Sammour, Carsten Hopf, Chávez-Gutiérrez Lucía
Integrative Single-Plaque Analysis Reveals Signature Aβ and Lipid Profiles in the Alzheimer's Brain. Analytical chemistry 96 (24) (2024)
Zoltowska Katarzyna Marta, Utpal Das, Sam Lismont, Thomas Enzlein, Maesako Masato, Mei C Q Houser, Maria Luisa Franco, Burcu Özcan, Gomes Moreira Diana, Dmitry Karachentsev, Ann Becker, Carsten Hopf, Marçal Vilar, Berezovska Oksana, William Mobley, Chávez-Gutiérrez Lucía
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling. eLife 12 (2024)
Enzlein Thomas, Tammaryn Lashley, Denis Abu Sammour, Carsten Hopf, Chávez-Gutiérrez Lucía
Integrative Single-Plaque Analysis Reveals Signature Aβ and Lipid Profiles in the Alzheimer's Brain. Analytical chemistry (2024)
Enzlein Thomas, Tammaryn Lashley, Denis Abu Sammour, Carsten Hopf, Chávez-Gutiérrez Lucía
Integrative Single-Plaque Analysis Reveals Signature Aβ and Lipid Profiles in the Alzheimer's Brain. Analytical chemistry 96 (24) (2024)
Zoltowska Katarzyna Marta, Utpal Das, Sam Lismont, Thomas Enzlein, Maesako Masato, Mei C Q Houser, Maria Luisa Franco, Burcu Özcan, Gomes Moreira Diana, Dmitry Karachentsev, Ann Becker, Carsten Hopf, Marçal Vilar, Berezovska Oksana, William Mobley, Chávez-Gutiérrez Lucía
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling. eLife 12 (2024)
Zoltowska Katarzyna Marta, Utpal Das, Sam Lismont, Thomas Enzlein, Maesako Masato, Mei C Q Houser, Maria Luisa Franco, Burcu Özcan, Gomes Moreira Diana, Dmitry Karachentsev, Ann Becker, Carsten Hopf, Marçal Vilar, Berezovska Oksana, William Mobley, Chávez-Gutiérrez Lucía
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling. eLife 12 (2024)
Enzlein Thomas, Tammaryn Lashley, Denis Abu Sammour, Carsten Hopf, Chávez-Gutiérrez Lucía
Integrative Single-Plaque Analysis Reveals Signature Aβ and Lipid Profiles in the Alzheimer's Brain. Analytical chemistry 96 (24) (2024)
Enzlein Thomas, Tammaryn Lashley, Denis Abu Sammour, Carsten Hopf, Chávez-Gutiérrez Lucía
Integrative Single-Plaque Analysis Reveals Signature Aβ and Lipid Profiles in the Alzheimer's Brain. Analytical chemistry 96 (24) (2024)
Matthias Koch, Enzlein Thomas, Shu-Yu Chen, Dieter Petit, Sam Lismont, Martin Zacharias, Carsten Hopf, Chávez-Gutiérrez Lucía
APP substrate ectodomain defines amyloid-β peptide length by restraining γ-secretase processivity and facilitating product release. The EMBO journal (2023)
Zoltowska Katarzyna Marta, Das Utpal, Lismont Sam, Enzlein Thomas, Maesako Masato, Mei Cq Houser, Franco María Luisa, Gomes Moreira Diana, Karachentsev Dmitry, Becker Ann, Carsten Hopf, Marçal Vilar, Berezovska Oksana, William C Mobley, Chávez-Gutiérrez Lucía
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling. bioRxiv : the preprint server for biology (2023)
Shu-Yu Chen, Lukas P Feilen, Chávez-Gutiérrez Lucía, Harald Steiner, Martin Zacharias
Enzyme-substrate hybrid β-sheet controls geometry and water access to the γ-secretase active site. Communications biology 6 (1) (2023)
Dieter Petit, Sara Gutiérrez Fernández, Zoltowska Katarzyna Marta, Enzlein Thomas, Natalie S Ryan, Antoinette O'Connor, Maria Szaruga, Elizabeth Hill, Rik Vandenberghe, Nick C Fox, Chávez-Gutiérrez Lucía
Aβ profiles generated by Alzheimer's disease causing PSEN1 variants determine the pathogenicity of the mutation and predict age at disease onset. Molecular psychiatry 27 (6) (2022)
Dieter Petit, Manuel Hitzenberger, Matthias Koch, Sam Lismont, Zoltowska Katarzyna Marta, Enzlein Thomas, Carsten Hopf, Martin Zacharias, Chávez-Gutiérrez Lucía
Enzyme-substrate interface targeting by imidazole-based γ-secretase modulators activates γ-secretase and stabilizes its interaction with APP. The EMBO journal 41 (21) (2022)
Zoltowska Katarzyna Marta, Chávez-Gutiérrez Lucía
Exploring the origins of nucleation. eLife 10 (2021)
Dieter Petit, Manuel Hitzenberger, Sam Lismont, Zoltowska Katarzyna Marta, Natalie S Ryan, Marc Mercken, Francois Bischoff, Martin Zacharias, Chávez-Gutiérrez Lucía
Extracellular interface between APP and Nicastrin regulates Aβ length and response to γ-secretase modulators. The EMBO journal 38 (12) (2019)
Hermien Acx, Lutgarde Serneels, Enrico Radaelli, Serge Muyldermans, Cécile Vincke, Elise Pepermans, Ulrike Müller, Chávez-Gutiérrez Lucía, Bart De Strooper
Inactivation of γ-secretases leads to accumulation of substrates and non-Alzheimer neurodegeneration. EMBO molecular medicine 9 (8) (2018)