Edward J Brignole

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 3

Top Topics

Induced Pluripotent Stem Cells

Structural Basis

Top Venues

Science (New York, N.Y.)

Massachusetts Institute of Technology

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts Institute of Technology Dec 05 2017

United States

Director of the Automated Cryogenic Electron Microscopy Center at MIT.nano :: Biology

Publications

Max L Valenstein, Kacper B Rogala, Pranav V Lalgudi, Edward J Brignole, Xin Gu, Robert A Saxton, Lynne Chantranupong, Jonas Kolibius, Jan-Philipp Quast, David M Sabatini
Structure of the nutrient-sensing hub GATOR2. Nature 607 (7919) (2022)
Kacper B Rogala, Xin Gu, Jibril F Kedir, Monther Abu-Remaileh, Laura F Bianchi, Alexia M S Bottino, Rikke Dueholm, Anna Niehaus, Daan Overwijn, Ange-Célia Priso Fils, Sherry X Zhou, Daniel D Leary, Nouf N Laqtom, Edward J Brignole, David M Sabatini
Structural basis for the docking of mTORC1 on the lysosomal surface. Science (New York, N.Y.) 366 (6464) (2019)
Edward J Brignole, Kuang-Lei Tsai, Johnathan Chittuluru, Haoran Li, Yimon Aye, Pawel A Penczek, JoAnne Stubbe, Catherine L Drennan, Francisco Asturias
3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound. eLife 7 (2018)