Douglas B Kell (Etheresia Pretorius)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 40

Top Venues

Seminars in thrombosis and hemostasis

Cardiovascular diabetology

Scientific reports

The Biochemical journal

Stellenbosch University

University of Pretoria (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Stellenbosch University Jan 1o 2017

South Africa

Research Professor :: Physiological sceinces

Education History

University of Pretoria Jan 1o 1994 - Sep 30o 1999

South Africa

PHD

Publications

Douglas B Kell, Douglas B Kell
A Perspective on How Fibrinaloid Microclots and Platelet Pathology May be Applied in Clinical Investigations. Seminars in thrombosis and hemostasis (2023)
Simone Turner, Caitlin A Naidoo, Thomas J Usher, Arneaux Kruger, Chantelle Venter, Gert J Laubscher, M Asad Khan, Douglas B Kell, Douglas B Kell
Increased Levels of Inflammatory and Endothelial Biomarkers in Blood of Long COVID Patients Point to Thrombotic Endothelialitis. Seminars in thrombosis and hemostasis (2023)
Douglas B Kell, Douglas B Kell
Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases? The Biochemical journal 480 (15) (2023)
Douglas B Kell, Chantelle Venter, Gert Jacobus Laubscher, Maritha J Kotze, Sunday O Oladejo, Liam R Watson, Kanshu Rajaratnam, Bruce W Watson, Douglas B Kell
Prevalence of symptoms, comorbidities, fibrin amyloid microclots and platelet pathology in individuals with Long COVID/Post-Acute Sequelae of COVID-19 (PASC). Cardiovascular diabetology 21 (1) (2022)
Douglas B Kell, Gert Jacobus Laubscher, Douglas B Kell
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications. The Biochemical journal 479 (4) (2022)
Lize M Grobbelaar, Arneaux Kruger, Chantelle Venter, Este M Burger, Gert J Laubscher, Tongai G Maponga, Maritha J Kotze, Hau C Kwaan, Joseph B Miller, Daniel Fulkerson, Wei Huff, Eric Chang, Grant Wiarda, Connor M Bunch, Mark M Walsh, Syed Raza, Mahmud Zamlut, Hunter B Moore, Ernest E Moore, Matthew D Neal, Douglas B Kell, Douglas B Kell
Relative Hypercoagulopathy of the SARS-CoV-2 Beta and Delta Variants when Compared to the Less Severe Omicron Variants Is Related to TEG Parameters, the Extent of Fibrin Amyloid Microclots, and the Severity of Clinical Illness. Seminars in thrombosis and hemostasis 48 (7) (2022)
Douglas B Kell, Douglas B Kell
The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications. The Biochemical journal 479 (16) (2022)
Arneaux Kruger, Mare Vlok, Simone Turner, Chantelle Venter, Gert Jacobus Laubscher, Douglas B Kell, Douglas B Kell
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system. Cardiovascular diabetology 21 (1) (2022)
Jean M Nunes, Arneaux Kruger, Amy Proal, Douglas B Kell, Douglas B Kell
The Occurrence of Hyperactivated Platelets and Fibrinaloid Microclots in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Pharmaceuticals (Basel, Switzerland) 15 (8) (2022)
Maria J E Visser, Chantelle Venter, Timothy J Roberts, Gareth Tarr, Douglas B Kell
Psoriatic disease is associated with systemic inflammation, endothelial activation, and altered haemostatic function. Scientific reports 11 (1) (2021)
Malebogo N Ngoepe, Douglas B Kell, Ilunga J Tshimanga, Zahra Shaikh, Yiannis Ventikos, Wei Hua Ho
Thrombin-Fibrinogen In Vitro Flow Model of Thrombus Growth in Cerebral Aneurysms. TH open : companion journal to thrombosis and haemostasis 5 (2) (2021)
Vladimir N Chubarev, Narasimha M Beeraka, Mikhail Yegorovich Sinelnikov, Kirill V Bulygin, Vladimir N Nikolenko, Elizaveta V Mikhaylenko, Vadim V Tarasov, Liudmila M Mikhaleva, Palmiro Poltronieri, Vijaya Padma Viswanadha, Siva G Somasundaram, Cecil E Kirkland, Kuo Chen, Junqi Liu, Ruitai Fan, Mohammad Amjad Kamal, Alexander A Mironov, SubbaRao V Madhunapantula, Douglas B Kell, Sergey V Dindyaev, Cristian Muresanu, Olga A Sukocheva
Health Science Community Will Miss This Bright and Uniting Star: In Memory of Professor Gjumrakch Aliev, M.D, Ph.D. Cancers 13 (8) (2021)
Gert Jacobus Laubscher, Petrus Johannes Lourens, Chantelle Venter, Douglas B Kell, Douglas B Kell
TEG®, Microclot and Platelet Mapping for Guiding Early Management of Severe COVID-19 Coagulopathy. Journal of clinical medicine 10 (22) (2021)
Siphosethu Cassandra Maphumulo, Douglas B Kell
Role of Circulating Microparticles in Type 2 Diabetes Mellitus: Implications for Pathological Clotting. Seminars in thrombosis and hemostasis 48 (2) (2021)
Martin J Page, Douglas B Kell
Platelet Behavior Contributes to Neuropathologies: A Focus on Alzheimer's and Parkinson's Disease. Seminars in thrombosis and hemostasis (2021)
Douglas B Kell, Mare Vlok, Chantelle Venter, Johannes A Bezuidenhout, Gert Jacobus Laubscher, Janami Steenkamp, Douglas B Kell
Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin. Cardiovascular diabetology 20 (1) (2021)
Lize M Grobbelaar, Chantelle Venter, Mare Vlok, Malebogo N Ngoepe, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp, Douglas B Kell, Douglas B Kell
SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19. Bioscience reports 41 (8) (2021)
Jean-Frédéric Brun, Emmanuelle Varlet-Marie, Justine Myzia, Eric Raynaud de Mauverger, Douglas B Kell
Metabolic Influences Modulating Erythrocyte Deformability and Eryptosis. Metabolites 12 (1) (2021)
Greta M de Waal, Willem J S de Villiers, Timothy Forgan, Timothy J Roberts, Douglas B Kell
Colorectal cancer is associated with increased circulating lipopolysaccharide, inflammation and hypercoagulability. Scientific reports 10 (1) (2020)
Oore-Ofe Olumuyiwa-Akeredolu, Martin J Page, Prashilla Soma, Douglas B Kell
Platelets: emerging facilitators of cellular crosstalk in rheumatoid arthritis. Nature reviews. Rheumatology 15 (4) (2020)
Martin J Page, Douglas B Kell
A Champion of Host Defense: A Generic Large-Scale Cause for Platelet Dysfunction and Depletion in Infection. Seminars in thrombosis and hemostasis 46 (3) (2020)
Brandon S Jackson, Julien Nunes Goncalves, Douglas B Kell
Comparison of pathological clotting using haematological, functional and morphological investigations in HIV-positive and HIV-negative patients with deep vein thrombosis. Retrovirology 17 (1) (2020)
Chantelle Venter, Johannes Andries Bezuidenhout, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp, Douglas B Kell, Douglas B Kell
Erythrocyte, Platelet, Serum Ferritin, and P-Selectin Pathophysiology Implicated in Severe Hypercoagulation and Vascular Complications in COVID-19. International journal of molecular sciences 21 (21) (2020)
Corlia Grobler, Siphosethu C Maphumulo, L Mireille Grobbelaar, Jhade C Bredenkamp, Gert J Laubscher, Petrus J Lourens, Douglas B Kell, Douglas B Kell, Etheresia Pretorius
Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes. International journal of molecular sciences 21 (14) (2020)
Marthinus Janse van Vuuren, Theodore Albertus Nell, Jonathan Ambrose Carr, Douglas B Kell, Douglas B Kell
Iron Dysregulation and Inflammagens Related to Oral and Gut Health Are Central to the Development of Parkinson's Disease. Biomolecules 11 (1) (2020)
Johannes A Bezuidenhout, Douglas B Kell
The Central Role of Acute Phase Proteins in Rheumatoid Arthritis: Involvement in Disease Autoimmunity, Inflammatory Responses, and the Heightened Risk of Cardiovascular Disease. Seminars in thrombosis and hemostasis 46 (4) (2020)
Douglas B Kell, Chantelle Venter, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp, Douglas B Kell
Prevalence of readily detected amyloid blood clots in 'unclotted' Type 2 Diabetes Mellitus and COVID-19 plasma: a preliminary report. Cardiovascular diabetology 19 (1) (2020)
Martin J Page, Greig J A Thomson, J Massimo Nunes, Anna-Mart Engelbrecht, Theodore Albertus Nell, Willem J S de Villiers, Maria C de Beer, Lize Engelbrecht, Douglas B Kell, Douglas B Kell
Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation. Scientific reports 9 (1) (2019)
Shehan N Randeria, Greig J A Thomson, Theodore Albertus Nell, Timothy J Roberts, Douglas B Kell
Inflammatory cytokines in type 2 diabetes mellitus as facilitators of hypercoagulation and abnormal clot formation. Cardiovascular diabetology 18 (1) (2019)
Douglas B Kell, Martin J Page, Lisa Hendricks, Nondumiso B Nkosi, Sven R Benson, Douglas B Kell
Both lipopolysaccharide and lipoteichoic acids potently induce anomalous fibrin amyloid formation: assessment with novel Amytracker™ stains. Journal of the Royal Society, Interface 15 (139) (2019)
Douglas B Kell, Douglas B Kell
No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases. Biological reviews of the Cambridge Philosophical Society 93 (3) (2018)
Douglas B Kell, Martin J Page, Sthembile Mbotwe, Douglas B Kell
Lipopolysaccharide-binding protein (LBP) can reverse the amyloid state of fibrin seen or induced in Parkinson's disease. PloS one 13 (3) (2018)
Greta M de Waal, Lize Engelbrecht, Tanja Davis, Willem J S de Villiers, Douglas B Kell, Douglas B Kell
Correlative Light-Electron Microscopy detects lipopolysaccharide and its association with fibrin fibres in Parkinson's Disease, Alzheimer's Disease and Type 2 Diabetes Mellitus. Scientific reports 8 (1) (2018)
Lesha Pretorius, Greig J A Thomson, Rozanne C M Adams, Theo A Nell, Willem A Laubscher, Douglas B Kell
Platelet activity and hypercoagulation in type 2 diabetes. Cardiovascular diabetology 17 (1) (2018)
Martin J Page, Janette Bester, Douglas B Kell
The inflammatory effects of TNF-α and complement component 3 on coagulation. Scientific reports 8 (1) (2018)
Douglas B Kell, Sthembile Mbotwe, Douglas B Kell
Lipopolysaccharide-binding protein (LBP) reverses the amyloid state of fibrin seen in plasma of type 2 diabetics with cardiovascular co-morbidities. Scientific reports 7 (1) (2017)
Prashilla Soma, Albe C Swanepoel, Janette Bester, Douglas B Kell
Tissue factor levels in type 2 diabetes mellitus. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 66 (5) (2017)
Douglas B Kell, Martin J Page, Lize Engelbrecht, Graham C Ellis, Douglas B Kell
Substantial fibrin amyloidogenesis in type 2 diabetes assessed using amyloid-selective fluorescent stains. Cardiovascular diabetology 16 (1) (2017)
Martin J Page, Janette Bester, Douglas B Kell
Interleukin-12 and its procoagulant effect on erythrocytes, platelets and fibrin(ogen): the lesser known side of inflammation. British journal of haematology 180 (1) (2017)
Douglas B Kell, Sthembile Mbotwe, Janette Bester, Christopher J Robinson, Douglas B Kell
Acute induction of anomalous and amyloidogenic blood clotting by molecular amplification of highly substoichiometric levels of bacterial lipopolysaccharide. Journal of the Royal Society, Interface 13 (122) (2017)

Douglas B Kell.css-eqlu8i{font-size:small;padding-left:4px;} (Etheresia Pretorius)

Publication Activity (10 Years)

Top Topics

Top Venues

Douglas B Kell (Etheresia Pretorius)