Douglas B Kell (Janami Steenkamp, D B Kell)

Scopus Author ID ResearcherID Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 57

Top Venues

Cardiovascular diabetology

Viruses

Pharmaceuticals (Basel, Switzerland)

Molecules (Basel, Switzerland)

University of Liverpool

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Liverpool Dec 01 2018

United Kingdom

Research Chair in Systems Biology :: Biochemistry

University of Liverpool Dec 01 2018

United Kingdom

Research Chair in Systems Biology :: Biochemistry

University of Manchester Sep 01 2002

United Kingdom

Research Chair in Bioanalytical Science :: Chemistry

Aberystwyth University Oct 01 1978 - Aug 31 2002

United Kingdom

Fellow, Lecturer, Reader, Professor :: Botany & Microbiology

Publications

Douglas B Kell, Muhammed Asad Khan, Binita Kane, Gregory Yoke Hong Lip, Douglas B Kell
Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID. Journal of personalized medicine 14 (2) (2024)
Douglas B Kell, Gregory Y H Lip, Douglas B Kell
Fibrinaloid Microclots and Atrial Fibrillation. Biomedicines 12 (4) (2024)
Douglas B Kell, Muhammed Asad Khan, Binita Kane, Gregory Yoke Hong Lip, Douglas B Kell
Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID. Journal of personalized medicine 14 (2) (2024)
Luana de Fátima Alves, Jennifer Bernadette Moore, Douglas B Kell
The Biology and Biochemistry of Kynurenic Acid, a Potential Nutraceutical with Multiple Biological Effects. International journal of molecular sciences 25 (16) (2024)
Chrispian W Theron, Jesus Enrique Salcedo-Sora, Justine M Grixti, Iben Møller-Hansen, Irina Borodina, Douglas B Kell
Evidence for the Role of the Mitochondrial ABC Transporter MDL1 in the Uptake of Clozapine and Related Molecules into the Yeast Saccharomyces cerevisiae . Pharmaceuticals (Basel, Switzerland) 17 (7) (2024)
Chrispian W Theron, Jesus Enrique Salcedo-Sora, Justine M Grixti, Iben Møller-Hansen, Irina Borodina, Douglas B Kell
Evidence for the Role of the Mitochondrial ABC Transporter MDL1 in the Uptake of Clozapine and Related Molecules into the Yeast Saccharomyces cerevisiae . Pharmaceuticals (Basel, Switzerland) 17 (7) (2024)
Jean M Nunes, Douglas B Kell, Douglas B Kell
Herpesvirus Infection of Endothelial Cells as a Systemic Pathological Axis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Viruses 16 (4) (2024)
Jean M Nunes, Douglas B Kell, Douglas B Kell
Herpesvirus Infection of Endothelial Cells as a Systemic Pathological Axis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Viruses 16 (4) (2024)
Douglas B Kell, Gregory Y H Lip, Douglas B Kell
Fibrinaloid Microclots and Atrial Fibrillation. Biomedicines 12 (4) (2024)
Douglas B Kell, Muhammed Asad Khan, Binita Kane, Gregory Yoke Hong Lip, Douglas B Kell
Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID. Journal of personalized medicine 14 (2) (2024)
Luana de Fátima Alves, Jennifer Bernadette Moore, Douglas B Kell
The Biology and Biochemistry of Kynurenic Acid, a Potential Nutraceutical with Multiple Biological Effects. International journal of molecular sciences 25 (16) (2024)
Chrispian W Theron, Jesus Enrique Salcedo-Sora, Justine M Grixti, Iben Møller-Hansen, Irina Borodina, Douglas B Kell
Evidence for the Role of the Mitochondrial ABC Transporter MDL1 in the Uptake of Clozapine and Related Molecules into the Yeast Saccharomyces cerevisiae . Pharmaceuticals (Basel, Switzerland) 17 (7) (2024)
Jean M Nunes, Douglas B Kell, Douglas B Kell
Herpesvirus Infection of Endothelial Cells as a Systemic Pathological Axis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Viruses 16 (4) (2024)
Jean M Nunes, Douglas B Kell, Douglas B Kell
Herpesvirus Infection of Endothelial Cells as a Systemic Pathological Axis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Viruses 16 (4) (2024)
Douglas B Kell, Douglas B Kell
A Perspective on How Fibrinaloid Microclots and Platelet Pathology May be Applied in Clinical Investigations. Seminars in thrombosis and hemostasis (2023)
Simone Turner, Caitlin A Naidoo, Thomas J Usher, Arneaux Kruger, Chantelle Venter, Gert J Laubscher, M Asad Khan, Douglas B Kell, Douglas B Kell
Increased Levels of Inflammatory and Endothelial Biomarkers in Blood of Long COVID Patients Point to Thrombotic Endothelialitis. Seminars in thrombosis and hemostasis (2023)
Douglas B Kell, Douglas B Kell
Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases? The Biochemical journal 480 (15) (2023)
Douglas B Kell, Chantelle Venter, Gert Jacobus Laubscher, Maritha J Kotze, Sunday O Oladejo, Liam R Watson, Kanshu Rajaratnam, Bruce W Watson, Douglas B Kell
Prevalence of symptoms, comorbidities, fibrin amyloid microclots and platelet pathology in individuals with Long COVID/Post-Acute Sequelae of COVID-19 (PASC). Cardiovascular diabetology 21 (1) (2022)
Douglas B Kell, Gert Jacobus Laubscher, Douglas B Kell
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications. The Biochemical journal 479 (4) (2022)
Mohammad S Radi, Lachlan J Munro, Jesus Enrique Salcedo-Sora, Se Hyeuk Kim, Adam M Feist, Douglas B Kell
Understanding Functional Redundancy and Promiscuity of Multidrug Transporters in E. coli under Lipophilic Cation Stress. Membranes 12 (12) (2022)
Lize M Grobbelaar, Arneaux Kruger, Chantelle Venter, Este M Burger, Gert J Laubscher, Tongai G Maponga, Maritha J Kotze, Hau C Kwaan, Joseph B Miller, Daniel Fulkerson, Wei Huff, Eric Chang, Grant Wiarda, Connor M Bunch, Mark M Walsh, Syed Raza, Mahmud Zamlut, Hunter B Moore, Ernest E Moore, Matthew D Neal, Douglas B Kell, Douglas B Kell
Relative Hypercoagulopathy of the SARS-CoV-2 Beta and Delta Variants when Compared to the Less Severe Omicron Variants Is Related to TEG Parameters, the Extent of Fibrin Amyloid Microclots, and the Severity of Clinical Illness. Seminars in thrombosis and hemostasis 48 (7) (2022)
Mohammad S Radi, Lachlan J Munro, Jesus Enrique Salcedo-Sora, Se Hyeuk Kim, Adam M Feist, Douglas B Kell
Understanding Functional Redundancy and Promiscuity of Multidrug Transporters in E. coli under Lipophilic Cation Stress. Membranes 12 (12) (2022)
Douglas B Kell, Douglas B Kell
The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications. The Biochemical journal 479 (16) (2022)
Arneaux Kruger, Mare Vlok, Simone Turner, Chantelle Venter, Gert Jacobus Laubscher, Douglas B Kell, Douglas B Kell
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system. Cardiovascular diabetology 21 (1) (2022)
Mohammad S Radi, Lachlan J Munro, Jesus Enrique Salcedo-Sora, Se Hyeuk Kim, Adam M Feist, Douglas B Kell
Understanding Functional Redundancy and Promiscuity of Multidrug Transporters in E. coli under Lipophilic Cation Stress. Membranes 12 (12) (2022)
Jean M Nunes, Arneaux Kruger, Amy Proal, Douglas B Kell, Douglas B Kell
The Occurrence of Hyperactivated Platelets and Fibrinaloid Microclots in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Pharmaceuticals (Basel, Switzerland) 15 (8) (2022)
Mohammad S Radi, Lachlan J Munro, Jesus Enrique Salcedo-Sora, Se Hyeuk Kim, Adam M Feist, Douglas B Kell
Understanding Functional Redundancy and Promiscuity of Multidrug Transporters in E. coli under Lipophilic Cation Stress. Membranes 12 (12) (2022)
Douglas B Kell
The Transporter-Mediated Cellular Uptake and Efflux of Pharmaceutical Drugs and Biotechnology Products: How and Why Phospholipid Bilayer Transport Is Negligible in Real Biomembranes. Molecules (Basel, Switzerland) 26 (18) (2021)
Steven A van der Hoek, Matej Rusnák, Irene Hjorth Jacobsen, José Luis Martinez, Douglas B Kell, Irina Borodina
Engineering ergothioneine production in Yarrowia lipolytica. FEBS letters (2021)
Gert Jacobus Laubscher, Petrus Johannes Lourens, Chantelle Venter, Douglas B Kell, Douglas B Kell
TEG®, Microclot and Platelet Mapping for Guiding Early Management of Severe COVID-19 Coagulopathy. Journal of clinical medicine 10 (22) (2021)
Aditya Divyakant Shrivastava, Douglas B Kell
FragNet, a Contrastive Learning-Based Transformer Model for Clustering, Interpreting, Visualizing, and Navigating Chemical Space. Molecules (Basel, Switzerland) 26 (7) (2021)
Jesus Enrique Salcedo-Sora, Amy T R Robison, Jacqueline Zaengle-Barone, Katherine J Franz, Douglas B Kell
Membrane Transporters Involved in the Antimicrobial Activities of Pyrithione in Escherichia coli. Molecules (Basel, Switzerland) 26 (19) (2021)
Lachlan J Munro, Douglas B Kell
Intelligent host engineering for metabolic flux optimisation in biotechnology. The Biochemical journal 478 (20) (2021)
Douglas B Kell, Mare Vlok, Chantelle Venter, Johannes A Bezuidenhout, Gert Jacobus Laubscher, Janami Steenkamp, Douglas B Kell
Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin. Cardiovascular diabetology 20 (1) (2021)
Lize M Grobbelaar, Chantelle Venter, Mare Vlok, Malebogo N Ngoepe, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp, Douglas B Kell, Douglas B Kell
SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19. Bioscience reports 41 (8) (2021)
Aditya Divyakant Shrivastava, Neil Swainston, Soumitra Samanta, Ivayla Roberts, Marina Wright Muelas, Douglas B Kell
MassGenie: A Transformer-Based Deep Learning Method for Identifying Small Molecules from Their Mass Spectra. Biomolecules 11 (12) (2021)
Yash Khemchandani, Stephen O'Hagan, Soumitra Samanta, Neil Swainston, Timothy J Roberts, Danushka Bollegala, Douglas B Kell
DeepGraphMolGen, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach. Journal of cheminformatics 12 (1) (2020)
Steve O'Hagan, Douglas B Kell
Structural Similarities between Some Common Fluorophores Used in Biology, Marketed Drugs, Endogenous Metabolites, and Natural Products. Marine drugs 18 (11) (2020)
Chantelle Venter, Johannes Andries Bezuidenhout, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp, Douglas B Kell, Douglas B Kell
Erythrocyte, Platelet, Serum Ferritin, and P-Selectin Pathophysiology Implicated in Severe Hypercoagulation and Vascular Complications in COVID-19. International journal of molecular sciences 21 (21) (2020)
Corlia Grobler, Siphosethu C Maphumulo, L Mireille Grobbelaar, Jhade C Bredenkamp, Gert J Laubscher, Petrus J Lourens, Douglas B Kell, Douglas B Kell, Etheresia Pretorius
Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes. International journal of molecular sciences 21 (14) (2020)
Irina Borodina, Louise C Kenny, Cathal M McCarthy, Kalaivani Paramasivan, Etheresia Pretorius, Timothy J Roberts, Steven A van der Hoek, Douglas B Kell
The biology of ergothioneine, an antioxidant nutraceutical. Nutrition research reviews 33 (2) (2020)
Marthinus Janse van Vuuren, Theodore Albertus Nell, Jonathan Ambrose Carr, Douglas B Kell, Douglas B Kell
Iron Dysregulation and Inflammagens Related to Oral and Gut Health Are Central to the Development of Parkinson's Disease. Biomolecules 11 (1) (2020)
Douglas B Kell
Hitchhiking into the cell. Nature chemical biology 16 (4) (2020)
Jesus Enrique Salcedo-Sora, Douglas B Kell
A Quantitative Survey of Bacterial Persistence in the Presence of Antibiotics: Towards Antipersister Antimicrobial Discovery. Antibiotics (Basel, Switzerland) 9 (8) (2020)
Soumitra Samanta, Steve O'Hagan, Neil Swainston, Timothy J Roberts, Douglas B Kell
VAE-Sim: A Novel Molecular Similarity Measure Based on a Variational Autoencoder. Molecules (Basel, Switzerland) 25 (15) (2020)
Douglas B Kell, Chantelle Venter, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp, Douglas B Kell
Prevalence of readily detected amyloid blood clots in 'unclotted' Type 2 Diabetes Mellitus and COVID-19 plasma: a preliminary report. Cardiovascular diabetology 19 (1) (2020)
Marina Wright Muelas, Farah Mughal, Steve O'Hagan, Philip J Day, Douglas B Kell
The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data. Scientific reports 9 (1) (2019)
Shaowei Zhang, Michiyo Sakuma, Girdhar Singh Deora, Colin W Levy, Alex Klausing, Carlo Breda, Kevin D Read, Chris D Edlin, Benjamin P Ross, Marina Wright Muelas, Philip J Day, Stephen O'Hagan, Douglas B Kell, Robert Schwarcz, David Leys, Derren J Heyes, Flaviano Giorgini, Nigel S Scrutton
A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Communications biology 2 (2019)
Douglas B Kell, Martin J Page, Lisa Hendricks, Nondumiso B Nkosi, Sven R Benson, Douglas B Kell
Both lipopolysaccharide and lipoteichoic acids potently induce anomalous fibrin amyloid formation: assessment with novel Amytracker™ stains. Journal of the Royal Society, Interface 15 (139) (2019)
Srijan Jindal, Lei Yang, Philip J Day, Douglas B Kell
Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli. BMC microbiology 19 (1) (2019)
Douglas B Kell, Douglas B Kell
No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases. Biological reviews of the Cambridge Philosophical Society 93 (3) (2018)
Greta M de Waal, Lize Engelbrecht, Tanja Davis, Willem J S de Villiers, Douglas B Kell, Douglas B Kell
Correlative Light-Electron Microscopy detects lipopolysaccharide and its association with fibrin fibres in Parkinson's Disease, Alzheimer's Disease and Type 2 Diabetes Mellitus. Scientific reports 8 (1) (2018)
Pablo Carbonell, Adrian J Jervis, Christopher J Robinson, Cunyu Yan, Mark Dunstan, Neil Swainston, Maria Vinaixa, Katherine A Hollywood, Andrew Currin, Nicholas J W Rattray, Sandra Taylor, Reynard Spiess, Rehana Sung, Alan R Williams, Donal Fellows, Natalie J Stanford, Paul Mulherin, Rosalind Le Feuvre, Perdita E Barran, Royston Goodacre, Nicholas J Turner, Carole Goble, George Guoqiang Chen, Douglas B Kell, Jason Micklefield, Rainer Breitling, Eriko Takano, Jean-Loup Faulon, Nigel S Scrutton
An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals. Communications biology 1 (2018)
Douglas B Kell, Sthembile Mbotwe, Douglas B Kell
Lipopolysaccharide-binding protein (LBP) reverses the amyloid state of fibrin seen in plasma of type 2 diabetics with cardiovascular co-morbidities. Scientific reports 7 (1) (2017)
Maria Glymenaki, A Barnes, S O'Hagan, G Warhurst, Andrew J McBain, Ian D Wilson, Douglas B Kell, K J Else, Sheena M Cruickshank
Stability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation. Scientific reports 7 (1) (2017)
Steve O'Hagan, Douglas B Kell
Analysing and Navigating Natural Products Space for Generating Small, Diverse, But Representative Chemical Libraries. Biotechnology journal 13 (1) (2017)
Steve O'Hagan, Douglas B Kell
Analysis of drug-endogenous human metabolite similarities in terms of their maximum common substructures. Journal of cheminformatics 9 (2017)

Douglas B Kell.css-eqlu8i{font-size:small;padding-left:4px;} (Janami Steenkamp, D B Kell)

Publication Activity (10 Years)

Top Topics

Top Venues

Douglas B Kell (Janami Steenkamp, D B Kell)