Frank Buchholz

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 35

Top Topics

Embryonic Stem Cells

Dna Methylation

Top Venues

Nature communications

Nucleic acids research

Life science alliance

Nature biotechnology

This page only lists publications with an associated author ORCID identifier.

Publications

Jenna Hoersten, Gloria Ruiz-Gómez, Maciej Paszkowski-Rogacz, Giorgio Gilioli, Pedro Manuel Guillem-Gloria, Felix Lansing, M Teresa Pisabarro, Frank Buchholz
Engineering spacer specificity of the Cre/loxP system. Nucleic acids research 52 (13) (2024)
Liliya Mukhametzyanova, Lukas Theo Schmitt, Julia Torres-Rivera, Teresa Rojo-Romanos, Felix Lansing, Maciej Paszkowski-Rogacz, Heike Hollak, Melanie Brux, Martina Augsburg, Paul Martin Schneider, Frank Buchholz
Activation of recombinases at specific DNA loci by zinc-finger domain insertions. Nature biotechnology (2024)
Marietta Döring, Melanie Brux, Maciej Paszkowski-Rogacz, Pedro Manuel Guillem-Gloria, Frank Buchholz, M Teresa Pisabarro, Mirko Theis
Nucleolar protein TAAP1/ C22orf46 confers pro-survival signaling in non-small cell lung cancer. Life science alliance 7 (4) (2024)
Liliya Mukhametzyanova, Lukas Theo Schmitt, Julia Torres-Rivera, Teresa Rojo-Romanos, Felix Lansing, Maciej Paszkowski-Rogacz, Heike Hollak, Melanie Brux, Martina Augsburg, Paul Martin Schneider, Frank Buchholz
Activation of recombinases at specific DNA loci by zinc-finger domain insertions. Nature biotechnology (2024)
Marietta Döring, Melanie Brux, Maciej Paszkowski-Rogacz, Pedro Manuel Guillem-Gloria, Frank Buchholz, M Teresa Pisabarro, Mirko Theis
Nucleolar protein TAAP1/ C22orf46 confers pro-survival signaling in non-small cell lung cancer. Life science alliance 7 (4) (2024)
Jenna Hoersten, Gloria Ruiz-Gómez, Maciej Paszkowski-Rogacz, Giorgio Gilioli, Pedro Manuel Guillem-Gloria, Felix Lansing, M Teresa Pisabarro, Frank Buchholz
Engineering spacer specificity of the Cre/loxP system. Nucleic acids research 52 (13) (2024)
Jenna Hoersten, Gloria Ruiz-Gómez, Maciej Paszkowski-Rogacz, Giorgio Gilioli, Pedro Manuel Guillem-Gloria, Felix Lansing, M Teresa Pisabarro, Frank Buchholz
Engineering spacer specificity of the Cre/loxP system. Nucleic acids research (2024)
Marietta Döring, Melanie Brux, Maciej Paszkowski-Rogacz, Pedro Manuel Guillem-Gloria, Frank Buchholz, M Teresa Pisabarro, Mirko Theis
Nucleolar protein TAAP1/ C22orf46 confers pro-survival signaling in non-small cell lung cancer. Life science alliance 7 (4) (2024)
Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocio Acuna-Hidalgo, Derek Reid, Kristin L Sikkink, Monika Mauermann, Edwin F Juarez, Anne Jenseit, James T Robinson, Kristian W Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G Coufal, Michael L Levy, Denise Malicki, Charlotte Hobbs, Stephen F Kingsmore, Shareef Nahas, Matija Snuderl, John Crawford, Robert J Wechsler-Reya, Tom Belle Davidson, Jennifer A Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin A Kumar, Michael D Taylor, Jeremy Rich, Frank Buchholz, Jill P Mesirov, Stefan M Pfister, Ferhat Ay, Jesse R Dixon, Marcel Kool, Lukas Chavez
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nature communications 14 (1) (2023)
Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocio Acuna-Hidalgo, Derek Reid, Kristin L Sikkink, Monika Mauermann, Edwin F Juarez, Anne Jenseit, James T Robinson, Kristian W Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G Coufal, Michael L Levy, Denise Malicki, Charlotte Hobbs, Stephen F Kingsmore, Shareef Nahas, Matija Snuderl, John Crawford, Robert J Wechsler-Reya, Tom Belle Davidson, Jennifer A Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin A Kumar, Michael D Taylor, Jeremy Rich, Frank Buchholz, Jill P Mesirov, Stefan M Pfister, Ferhat Ay, Jesse R Dixon, Marcel Kool, Lukas Chavez
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nature communications 14 (1) (2023)
Milica Jelicic, Lukas Theo Schmitt, Maciej Paszkowski-Rogacz, Angelika Walder, Nadja Schubert, Jenna Hoersten, Duran Sürün, Frank Buchholz
Discovery and characterization of novel Cre-type tyrosine site-specific recombinases for advanced genome engineering. Nucleic acids research (2023)
Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocio Acuna-Hidalgo, Derek Reid, Kristin L Sikkink, Monika Mauermann, Edwin F Juarez, Anne Jenseit, James T Robinson, Kristian W Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G Coufal, Michael L Levy, Denise Malicki, Charlotte Hobbs, Stephen F Kingsmore, Shareef Nahas, Matija Snuderl, John Crawford, Robert J Wechsler-Reya, Tom Belle Davidson, Jennifer A Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin A Kumar, Michael D Taylor, Jeremy Rich, Frank Buchholz, Jill P Mesirov, Stefan M Pfister, Ferhat Ay, Jesse R Dixon, Marcel Kool, Lukas Chavez
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nature communications 14 (1) (2023)
Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocio Acuna-Hidalgo, Derek Reid, Kristin L Sikkink, Monika Mauermann, Edwin F Juarez, Anne Jenseit, James T Robinson, Kristian W Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G Coufal, Michael L Levy, Denise Malicki, Charlotte Hobbs, Stephen F Kingsmore, Shareef Nahas, Matija Snuderl, John Crawford, Robert J Wechsler-Reya, Tom Belle Davidson, Jennifer A Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin A Kumar, Michael D Taylor, Jeremy Rich, Frank Buchholz, Jill P Mesirov, Stefan M Pfister, Ferhat Ay, Jesse R Dixon, Marcel Kool, Lukas Chavez
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nature communications 14 (1) (2023)
Lukas Theo Schmitt, Aksana Schneider, Jonas Posorski, Felix Lansing, Milica Jelicic, Manavi Jain, Shady Sayed, Frank Buchholz, Duran Sürün
Quantification of evolved DNA-editing enzymes at scale with DEQSeq. Genome biology 24 (1) (2023)
Daniel Martin Klotz, Franziska Maria Schwarz, Anna Dubrovska, Kati Schuster, Mirko Theis, Alexander Krüger, Oliver Kutz, Theresa Link, Pauline Wimberger, Stephan Drukewitz, Frank Buchholz, Jürgen Thomale, Jan Dominik Kuhlmann
Establishment and Molecular Characterization of an In Vitro Model for PARPi-Resistant Ovarian Cancer. Cancers 15 (15) (2023)
Jovan Mircetic, Aylin Camgöz, Moustafa Abohawya, Li Ding, Julia Dietzel, Sebastián García Tobar, Maciej Paszkowski-Rogacz, Therese Seidlitz, Tim Schmäche, Marie-Christin Mehnert, Olga Sidorova, Jürgen Weitz, Frank Buchholz, Daniel E Stange
CRISPR/Cas9 Screen in Gastric Cancer Patient-Derived Organoids Reveals KDM1A-NDRG1 Axis as a Targetable Vulnerability. Small methods (2023)
Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocio Acuna-Hidalgo, Derek Reid, Kristin L Sikkink, Monika Mauermann, Edwin F Juarez, Anne Jenseit, James T Robinson, Kristian W Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G Coufal, Michael L Levy, Denise Malicki, Charlotte Hobbs, Stephen F Kingsmore, Shareef Nahas, Matija Snuderl, John Crawford, Robert J Wechsler-Reya, Tom Belle Davidson, Jennifer A Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin A Kumar, Michael D Taylor, Jeremy Rich, Frank Buchholz, Jill P Mesirov, Stefan M Pfister, Ferhat Ay, Jesse R Dixon, Marcel Kool, Lukas Chavez
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nature communications 14 (1) (2023)
Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocio Acuna-Hidalgo, Derek Reid, Kristin L Sikkink, Monika Mauermann, Edwin F Juarez, Anne Jenseit, James T Robinson, Kristian W Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G Coufal, Michael L Levy, Denise Malicki, Charlotte Hobbs, Stephen F Kingsmore, Shareef Nahas, Matija Snuderl, John Crawford, Robert J Wechsler-Reya, Tom Belle Davidson, Jennifer A Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin A Kumar, Michael D Taylor, Jeremy Rich, Frank Buchholz, Jill P Mesirov, Stefan M Pfister, Ferhat Ay, Jesse R Dixon, Marcel Kool, Lukas Chavez
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nature communications 14 (1) (2023)
Olga Alexandra Sidorova, Shady Sayed, Maciej Paszkowski-Rogacz, Michael Seifert, Aylin Camgöz, Ingo Roeder, Martin Bornhäuser, Christian Thiede, Frank Buchholz
RNAi-Mediated Screen of Primary AML Cells Nominates MDM4 as a Therapeutic Target in NK-AML with DNMT3A Mutations. Cells 11 (5) (2022)
Jenna Hoersten, Gloria Ruiz-Gómez, Felix Lansing, Teresa Rojo-Romanos, Lukas Theo Schmitt, Jan Sonntag, M Teresa Pisabarro, Frank Buchholz
Pairing of single mutations yields obligate Cre-type site-specific recombinases. Nucleic acids research 50 (2) (2022)
Lukas Theo Schmitt, Maciej Paszkowski-Rogacz, Florian Jug, Frank Buchholz
Prediction of designer-recombinases for DNA editing with generative deep learning. Nature communications 13 (1) (2022)
Lukas Theo Schmitt, Maciej Paszkowski-Rogacz, Florian Jug, Frank Buchholz
Prediction of designer-recombinases for DNA editing with generative deep learning. Nature communications 13 (1) (2022)
Li Ding, Lukas Theo Schmitt, Melanie Brux, Duran Sürün, Martina Augsburg, Felix Lansing, Jovan Mircetic, Mirko Theis, Frank Buchholz
DNA methylation-independent long-term epigenetic silencing with dCRISPR/Cas9 fusion proteins. Life science alliance 5 (6) (2022)
Lukas Theo Schmitt, Maciej Paszkowski-Rogacz, Florian Jug, Frank Buchholz
Prediction of designer-recombinases for DNA editing with generative deep learning. Nature communications 13 (1) (2022)
Felix Lansing, Liliya Mukhametzyanova, Teresa Rojo-Romanos, Kentaro Iwasawa, Masaki Kimura, Maciej Paszkowski-Rogacz, Janet Karpinski, Tobias Grass, Jan Sonntag, Paul Martin Schneider, Ceren Günes, Jenna Hoersten, Lukas Theo Schmitt, Natalia Rodriguez-Muela, Ralf Knöfler, Takanori Takebe, Frank Buchholz
Correction of a Factor VIII genomic inversion with designer-recombinases. Nature communications 13 (1) (2022)
Lukas Theo Schmitt, Maciej Paszkowski-Rogacz, Florian Jug, Frank Buchholz
Prediction of designer-recombinases for DNA editing with generative deep learning. Nature communications 13 (1) (2022)
Shady Sayed, Olga A Sidorova, Alexander Hennig, Martina Augsburg, Catherine P Cortés Vesga, Moustafa Abohawya, Lukas Theo Schmitt, Duran Sürün, Daniel E Stange, Jovan Mircetic, Frank Buchholz
Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing. Cancer research 82 (17) (2022)
Maximilian Clausing, Doreen William, Matthias Preussler, Julia Biedermann, Konrad Grützmann, Susan Richter, Frank Buchholz, Achim Temme, Evelin Schröck, Barbara Klink
Different Effects of RNAi-Mediated Downregulation or Chemical Inhibition of NAMPT in an Isogenic IDH Mutant and Wild-Type Glioma Cell Model. International journal of molecular sciences 23 (10) (2022)
Elisa Donato, Nadia C Correia, Carolin Andresen, Darja Karpova, Roberto Würth, Corinna Klein, Markus Sohn, Adriana Przybylla, Petra Zeisberger, Kathrin Rothfelder, Helmut R Salih, Halvard Bonig, Sebastian Stasik, Christoph Röllig, Anna Dolnik, Lars Bullinger, Frank Buchholz, Christian Thiede, Daniel Hübschmann, Andreas Trumpp
Retained functional normal and preleukemic HSCs at diagnosis are associated to good prognosis in DNMT3Amut NPM1mut AMLs. Blood advances (2022)
Alena Uvizl, Ruchi Goswami, Shanil Durgeshkumar Gandhi, Martina Augsburg, Frank Buchholz, Jochen Guck, Jörg Mansfeld, Salvatore Girardo
Efficient and gentle delivery of molecules into cells with different elasticity via Progressive Mechanoporation. Lab on a chip 21 (12) (2021)
Sandeep Sreevalsan, Marietta Döring, Maciej Paszkowski-Rogacz, Melanie Brux, Carolina Blanck, Marten Meyer, Frank Momburg, Frank Buchholz, Mirko Theis
MLLT6 maintains PD-L1 expression and mediates tumor immune resistance. EMBO reports 21 (12) (2020)
Li Ding, Maciej Paszkowski-Rogacz, Jovan Mircetic, Debojyoti Chakraborty, Frank Buchholz
The Paf1 complex positively regulates enhancer activity in mouse embryonic stem cells. Life science alliance 4 (3) (2020)
Duran Sürün, Aksana Schneider, Jovan Mircetic, Katrin Neumann, Felix Lansing, Maciej Paszkowski-Rogacz, Vanessa Hänchen, Min Ae Lee-Kirsch, Frank Buchholz
Efficient Generation and Correction of Mutations in Human iPS Cells Utilizing mRNAs of CRISPR Base Editors and Prime Editors. Genes 11 (5) (2020)
Daniela Mayer, Michael B Stadler, Melanie Rittirsch, Daniel Hess, Ilya Lukonin, Maria Winzi, Austin G Smith, Frank Buchholz, Joerg Betschinger
Zfp281 orchestrates interconversion of pluripotent states by engaging Ehmt1 and Zic2. The EMBO journal 39 (2) (2019)
Arne Jahn, Grishma Rane, Maciej Paszkowski-Rogacz, Sergi Sayols, Alina Bluhm, Chung-Ting Han, Irena Draškovič, José-Arturo Londono-Vallejo, Alan Prem Kumar, Frank Buchholz, Falk Butter, Dennis Kappei
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator. EMBO reports 18 (6) (2017)