George P Lisi

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 34

Top Topics

Molecular Dynamics Simulations

High Resolution

Single Molecule

Top Venues

Nature communications

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Erin Skeens, Federica Maschietto, Ramu Manjula, Shanelle R Shillingford, Elias J Lolis, Victor S Batista, Anton M Bennett, George P Lisi
Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase. bioRxiv : the preprint server for biology (2024)
Gabriel Monteiro da Silva, Jennifer Y Cui, David C Dalgarno, George P Lisi, Brenda Marilyn Rubenstein
High-throughput prediction of protein conformational distributions with subsampled AlphaFold2. Nature communications 15 (1) (2024)
Gabriel Monteiro da Silva, Jennifer Y Cui, David C Dalgarno, George P Lisi, Brenda Marilyn Rubenstein
High-throughput prediction of protein conformational distributions with subsampled AlphaFold2. Nature communications 15 (1) (2024)
Erin Skeens, Souvik Sinha, Mohd Ahsan, Alexandra M D'Ordine, Gerwald Jogl, Giulia Palermo, George P Lisi
High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9. Science advances 10 (10) (2024)
Gabriel Monteiro da Silva, Jennifer Y Cui, David C Dalgarno, George P Lisi, Brenda Marilyn Rubenstein
Author Correction: High-throughput prediction of protein conformational distributions with subsampled AlphaFold2. Nature communications 15 (1) (2024)
Erin Skeens, Souvik Sinha, Mohd Ahsan, Alexandra M D'Ordine, Gerwald Jogl, Giulia Palermo, George P Lisi
High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9. Science advances 10 (10) (2024)
Gabriel Monteiro da Silva, Jennifer Y Cui, David C Dalgarno, George P Lisi, Brenda Marilyn Rubenstein
High-throughput prediction of protein conformational distributions with subsampled AlphaFold2. Nature communications 15 (1) (2024)
Gabriel Monteiro da Silva, Jennifer Y Cui, David C Dalgarno, George P Lisi, Brenda Marilyn Rubenstein
High-throughput prediction of protein conformational distributions with subsampled AlphaFold2. Nature communications 15 (1) (2024)
Gabriel Monteiro da Silva, Jennifer Y Cui, David C Dalgarno, George P Lisi, Brenda Marilyn Rubenstein
Author Correction: High-throughput prediction of protein conformational distributions with subsampled AlphaFold2. Nature communications 15 (1) (2024)
Gabriel Monteiro da Silva, Jennifer Y Cui, David C Dalgarno, George P Lisi, Brenda Marilyn Rubenstein
High-throughput prediction of protein conformational distributions with subsampled AlphaFold2. Nature communications 15 (1) (2024)
Erin Skeens, Souvik Sinha, Mohd Ahsan, Alexandra M D'Ordine, Gerwald Jogl, Giulia Palermo, George P Lisi
High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9. Science advances 10 (10) (2024)
Gabriel Monteiro da Silva, Jennifer Y Cui, David C Dalgarno, George P Lisi, Brenda Marilyn Rubenstein
High-throughput prediction of protein conformational distributions with subsampled AlphaFold2. Nature communications 15 (1) (2024)
Helen B Belato, Alexa L Knight, Alexandra M D'Ordine, Zhiqiang Fan, Jinping Luo, Gerwald Jogl, George P Lisi
Atomistic Tuning of the GeoCas9 Recognition Lobe Modulates Allosteric Motions and Guide RNA Interactions. bioRxiv : the preprint server for biology (2024)
Erin Skeens, Souvik Sinha, Mohd Ahsan, Alexandra M D'Ordine, Gerwald Jogl, Giulia Palermo, George P Lisi
High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9. Science advances 10 (10) (2024)
Helen B Belato, George P Lisi
The Many (Inter)faces of Anti-CRISPRs: Modulation of CRISPR-Cas Structure and Dynamics by Mechanistically Diverse Inhibitors. Biomolecules 13 (2) (2023)
Helen B Belato, George P Lisi
The Many (Inter)faces of Anti-CRISPRs: Modulation of CRISPR-Cas Structure and Dynamics by Mechanistically Diverse Inhibitors. Biomolecules 13 (2) (2023)
Helen B Belato, George P Lisi
The Many (Inter)faces of Anti-CRISPRs: Modulation of CRISPR-Cas Structure and Dynamics by Mechanistically Diverse Inhibitors. Biomolecules 13 (2) (2023)
Erin Skeens, Souvik Sinha, Mohd Ahsan, Alexandra M D'Ordine, Gerwald Jogl, Giulia Palermo, George P Lisi
High-Fidelity, Hyper-Accurate, and Evolved Mutants Rewire Atomic Level Communication in CRISPR-Cas9. bioRxiv : the preprint server for biology (2023)
Gabriel Monteiro da Silva, Jennifer Y Cui, David C Dalgarno, George P Lisi, Brenda Marilyn Rubenstein
Predicting Relative Populations of Protein Conformations without a Physics Engine Using AlphaFold2. bioRxiv : the preprint server for biology (2023)
Helen B Belato, George P Lisi
The Many (Inter)faces of Anti-CRISPRs: Modulation of CRISPR-Cas Structure and Dynamics by Mechanistically Diverse Inhibitors. Biomolecules 13 (2) (2023)
Helen B Belato, George P Lisi
The Many (Inter)faces of Anti-CRISPRs: Modulation of CRISPR-Cas Structure and Dynamics by Mechanistically Diverse Inhibitors. Biomolecules 13 (2) (2023)
Helen B Belato, Carmelissa Norbrun, Jinping Luo, Chinmai Pindi, Souvik Sinha, Alexandra M D'Ordine, Gerwald Jogl, Giulia Palermo, George P Lisi
Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage. The Journal of chemical physics 157 (22) (2022)
Helen B Belato, Carmelissa Norbrun, Jinping Luo, Chinmai Pindi, Souvik Sinha, Alexandra M D'Ordine, Gerwald Jogl, Giulia Palermo, George P Lisi
Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage. The Journal of chemical physics 157 (22) (2022)
Jimin Wang, Yuanjun Shi, Krystle Reiss, Federica Maschietto, Elias J Lolis, William H Konigsberg, George P Lisi, Victor S Batista
Structural Insights into Binding of Remdesivir Triphosphate within the Replication-Transcription Complex of SARS-CoV-2. Biochemistry 61 (18) (2022)
Jimin Wang, Erin Skeens, Pablo Ricardo Arantes, Federica Maschietto, Brandon Allen, Gregory W Kyro, George P Lisi, Giulia Palermo, Victor S Batista
Structural Basis for Reduced Dynamics of Three Engineered HNH Endonuclease Lys-to-Ala Mutants for the Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-Associated 9 (CRISPR/Cas9) Enzyme. Biochemistry 61 (9) (2022)
Jimin Wang, Yuanjun Shi, Krystle Reiss, Brandon Allen, Federica Maschietto, Elias J Lolis, William H Konigsberg, George P Lisi, Victor S Batista
Insights into Binding of Single-Stranded Viral RNA Template to the Replication-Transcription Complex of SARS-CoV-2 for the Priming Reaction from Molecular Dynamics Simulations. Biochemistry 61 (6) (2022)
Helen B Belato, Carmelissa Norbrun, Jinping Luo, Chinmai Pindi, Souvik Sinha, Alexandra M D'Ordine, Gerwald Jogl, Giulia Palermo, George P Lisi
Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage. The Journal of chemical physics 157 (22) (2022)
Kyle W East, Frank Delaglio, George P Lisi
A simple approach for reconstruction of non-uniformly sampled pseudo-3D NMR data for accurate measurement of spin relaxation parameters. Journal of biomolecular NMR 75 (6-7) (2021)
Lukasz Nierzwicki, Kyle W East, Uriel N Morzan, Pablo R Arantes, Victor S Batista, George P Lisi, Giulia Palermo
Enhanced specificity mutations perturb allosteric signaling in CRISPR-Cas9. eLife 10 (2021)
Kyle W East, Jocelyn C Newton, Uriel N Morzan, Yogesh B Narkhede, Atanu Acharya, Erin Skeens, Gerwald Jogl, Victor S Batista, Giulia Palermo, George P Lisi
Allosteric Motions of the CRISPR-Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics. Journal of the American Chemical Society 142 (3) (2020)
Erin Skeens, Kyle W East, George P Lisi
1H, 13C, 15 N backbone resonance assignment of the recognition lobe subdomain 3 (Rec3) from Streptococcus pyogenes CRISPR-Cas9. Biomolecular NMR assignments 15 (1) (2020)
Jennifer Y Cui, Fuming Zhang, Lukasz Nierzwicki, Giulia Palermo, Robert J Linhardt, George P Lisi
Mapping the Structural and Dynamic Determinants of pH-Sensitive Heparin Binding to Granulocyte Macrophage Colony Stimulating Factor. Biochemistry 59 (38) (2020)
Kyle W East, Erin Skeens, Jennifer Y Cui, Helen B Belato, Brandon Mitchell, Rohaine Hsu, Victor S Batista, Giulia Palermo, George P Lisi
NMR and computational methods for molecular resolution of allosteric pathways in enzyme complexes. Biophysical reviews 12 (1) (2019)
Helen B Belato, Kyle W East, George P Lisi
1H, 13C, 15N backbone and side chain resonance assignment of the HNH nuclease from Streptococcus pyogenes CRISPR-Cas9. Biomolecular NMR assignments 13 (2) (2019)