Guohui Sun

中国科学家在线 Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 31

Top Topics

Molecular Docking

Machine Learning

Intellectual Disability

Top Venues

International journal of environmental research and public health

Journal of chemical information and modeling

Molecules (Basel, Switzerland)

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Tengjiao Fan, Lin Shen, Yaxin Huang, Xin Wang, Lijiao Zhao, Rugang Zhong, Peng Wang, Guohui Sun
Lonidamine Increases the Cytotoxic Effect of 1-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3-nitrosourea via Energy Inhibition, Disrupting Redox Homeostasis, and Downregulating MGMT Expression in Human Lung Cancer Cell Line. ACS omega 9 (34) (2024)
Jiaojiao Wang, Ting Ren, Guohui Sun, Na Zhang, Lijiao Zhao, Rugang Zhong
Mechanism of AGT-Mediated Repair of dG-dC Cross-Links in the Drug Resistance to Chloroethylnitrosoureas: Molecular Docking, MD Simulation, and ONIOM (QM/MM) Investigation. Journal of chemical information and modeling 64 (8) (2024)
Tengjiao Fan, Lin Shen, Yaxin Huang, Xin Wang, Lijiao Zhao, Rugang Zhong, Peng Wang, Guohui Sun
Lonidamine Increases the Cytotoxic Effect of 1-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3-nitrosourea via Energy Inhibition, Disrupting Redox Homeostasis, and Downregulating MGMT Expression in Human Lung Cancer Cell Line. ACS omega 9 (34) (2024)
Yaxing Huang, Peng Wang, Tengjiao Fan, Na Zhang, Lijiao Zhao, Rugang Zhong, Guohui Sun
Energy Blocker Lonidamine Reverses Nimustine Resistance in Human Glioblastoma Cells through Energy Blockade, Redox Homeostasis Disruption, and O 6 -Methylguanine-DNA Methyltransferase Downregulation: In Vitro and In Vivo Validation. ACS pharmacology & translational science 7 (5) (2024)
Xinyi Lu, Xin Wang, Shuo Chen, Tengjiao Fan, Lijiao Zhao, Rugang Zhong, Guohui Sun
The rat acute oral toxicity of trifluoromethyl compounds (TFMs): a computational toxicology study combining the 2D-QSTR, read-across and consensus modeling methods. Archives of toxicology 98 (7) (2024)
Yaxing Huang, Peng Wang, Tengjiao Fan, Na Zhang, Lijiao Zhao, Rugang Zhong, Guohui Sun
Energy Blocker Lonidamine Reverses Nimustine Resistance in Human Glioblastoma Cells through Energy Blockade, Redox Homeostasis Disruption, and O 6 -Methylguanine-DNA Methyltransferase Downregulation: In Vitro and In Vivo Validation. ACS pharmacology & translational science 7 (5) (2024)
Jiaojiao Wang, Ting Ren, Guohui Sun, Na Zhang, Lijiao Zhao, Rugang Zhong
Mechanism of AGT-Mediated Repair of dG-dC Cross-Links in the Drug Resistance to Chloroethylnitrosoureas: Molecular Docking, MD Simulation, and ONIOM (QM/MM) Investigation. Journal of chemical information and modeling (2024)
Jiaojiao Wang, Ting Ren, Guohui Sun, Na Zhang, Lijiao Zhao, Rugang Zhong
Mechanism of AGT-Mediated Repair of dG-dC Cross-Links in the Drug Resistance to Chloroethylnitrosoureas: Molecular Docking, MD Simulation, and ONIOM (QM/MM) Investigation. Journal of chemical information and modeling 64 (8) (2024)
Jiaojiao Wang, Ting Ren, Guohui Sun, Na Zhang, Lijiao Zhao, Rugang Zhong
Mechanism of AGT-Mediated Repair of dG-dC Cross-Links in the Drug Resistance to Chloroethylnitrosoureas: Molecular Docking, MD Simulation, and ONIOM (QM/MM) Investigation. Journal of chemical information and modeling 64 (8) (2024)
Xinyi Lu, Xin Wang, Shuo Chen, Tengjiao Fan, Lijiao Zhao, Rugang Zhong, Guohui Sun
The rat acute oral toxicity of trifluoromethyl compounds (TFMs): a computational toxicology study combining the 2D-QSTR, read-across and consensus modeling methods. Archives of toxicology (2024)
Jiaojiao Wang, Ting Ren, Guohui Sun, Na Zhang, Lijiao Zhao, Rugang Zhong
Mechanism of AGT-Mediated Repair of dG-dC Cross-Links in the Drug Resistance to Chloroethylnitrosoureas: Molecular Docking, MD Simulation, and ONIOM (QM/MM) Investigation. Journal of chemical information and modeling 64 (8) (2024)
Guohui Sun, Peiying Bai, Tengjiao Fan, Lijiao Zhao, Rugang Zhong, R Stanley McElhinney, T Brian H McMurry, Dorothy J Donnelly, Joan E McCormick, Jane Kelly, Geoffrey P Margison
QSAR and Chemical Read-Across Analysis of 370 Potential MGMT Inactivators to Identify the Structural Features Influencing Inactivation Potency. Pharmaceutics 15 (8) (2023)
Guohui Sun, Chongwen Wang
Molecular Toxicology and Cancer Prevention. Molecules (Basel, Switzerland) 28 (23) (2023)
Chao Zhang, Ning Ma, Guohui Sun
Using Grounded Theory to Identify Online Public Opinion in China to Improve Risk Management-The Case of COVID-19. International journal of environmental research and public health 19 (22) (2022)
Shuang Ma, Kang Cao, Shuangjin Li, Yaozhi Luo, Ke Wang, Wei Liu, Guohui Sun
Examining the Human Activity-Intensity Change at Different Stages of the COVID-19 Pandemic across Chinese Working, Residential and Entertainment Areas. International journal of environmental research and public health 20 (1) (2022)
Shuang Ma, Kang Cao, Shuangjin Li, Yaozhi Luo, Ke Wang, Wei Liu, Guohui Sun
Examining the Human Activity-Intensity Change at Different Stages of the COVID-19 Pandemic across Chinese Working, Residential and Entertainment Areas. International journal of environmental research and public health 20 (1) (2022)
Shuang Ma, Kang Cao, Shuangjin Li, Yaozhi Luo, Ke Wang, Wei Liu, Guohui Sun
Examining the Human Activity-Intensity Change at Different Stages of the COVID-19 Pandemic across Chinese Working, Residential and Entertainment Areas. International journal of environmental research and public health 20 (1) (2022)
Shuang Ma, Kang Cao, Shuangjin Li, Yaozhi Luo, Ke Wang, Wei Liu, Guohui Sun
Examining the Human Activity-Intensity Change at Different Stages of the COVID-19 Pandemic across Chinese Working, Residential and Entertainment Areas. International journal of environmental research and public health 20 (1) (2022)
Shuang Ma, Kang Cao, Shuangjin Li, Yaozhi Luo, Ke Wang, Wei Liu, Guohui Sun
Examining the Human Activity-Intensity Change at Different Stages of the COVID-19 Pandemic across Chinese Working, Residential and Entertainment Areas. International journal of environmental research and public health 20 (1) (2022)
Mengzhou Bi, Zhen Guan, Tengjiao Fan, Na Zhang, Jianhua Wang, Guohui Sun, Lijiao Zhao, Rugang Zhong
Identification of Pharmacophoric Fragments of DYRK1A Inhibitors Using Machine Learning Classification Models. Molecules (Basel, Switzerland) 27 (6) (2022)
Ning Ma, Sa Ma, Shuangjin Li, Shuang Ma, Xinzhi Pan, Guohui Sun
The Study of Spatial Safety and Social Psychological Health Features of Deaf Children and Children with an Intellectual Disability in the Public School Environment Based on the Visual Access and Exposure (VAE) Model. International journal of environmental research and public health 18 (8) (2021)
Tao Huang, Guohui Sun, Lijiao Zhao, Na Zhang, Rugang Zhong, Yongzhen Peng
Quantitative Structure-Activity Relationship (QSAR) Studies on the Toxic Effects of Nitroaromatic Compounds (NACs): A Systematic Review. International journal of molecular sciences 22 (16) (2021)
Chao Zhang, Lei Hong, Ning Ma, Guohui Sun
Logic Analysis of How the Emergency Management Legal System Used to Deal with Public Emerging Infectious Diseases under Balancing of Competing Interests-The Case of COVID-19. Healthcare (Basel, Switzerland) 9 (7) (2021)
Fangzheng Yin, Lijiao Zhao, Lili Zhang, Yuhe Chen, Guohui Sun, Jintao Li, Na Zhang, Yuancong Xu, Paul Kay Sheung Chan, Rugang Zhong
Chemopreventive Role of Apigenin against the Synergistic Carcinogenesis of Human Papillomavirus and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone. Biomedicines 8 (11) (2020)
Chunqiong Li, Xuewen Zhang, Na Zhang, Yue Zhou, Guohui Sun, Lijiao Zhao, Rugang Zhong
Identification and Biological Evaluation of CK2 Allosteric Fragments through Structure-Based Virtual Screening. Molecules (Basel, Switzerland) 25 (1) (2020)
Yaxin Huang, Guohui Sun, Xiaodong Sun, Feifan Li, Lijiao Zhao, Rugang Zhong, Yongzhen Peng
The Potential of Lonidamine in Combination with Chemotherapy and Physical Therapy in Cancer Treatment. Cancers 12 (11) (2020)
Tengjiao Fan, Guohui Sun, Xiaodong Sun, Lijiao Zhao, Rugang Zhong, Yongzhen Peng
Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment. Cancers 11 (3) (2019)
Tengjiao Fan, Guohui Sun, Lijiao Zhao, Xin Cui, Rugang Zhong
Metabolic Activation and Carcinogenesis of Tobacco-Specific Nitrosamine N'-Nitrosonornicotine (NNN): A Density Function Theory and Molecular Docking Study. International journal of environmental research and public health 16 (2) (2019)
Weinan Xiao, Guohui Sun, Tengjiao Fan, Junjun Liu, Na Zhang, Lijiao Zhao, Rugang Zhong
Reductive Activity and Mechanism of Hypoxia- Targeted AGT Inhibitors: An Experimental and Theoretical Investigation. International journal of molecular sciences 20 (24) (2019)
Tengjiao Fan, Guohui Sun, Lijiao Zhao, Xin Cui, Rugang Zhong
QSAR and Classification Study on Prediction of Acute Oral Toxicity of N-Nitroso Compounds. International journal of molecular sciences 19 (10) (2018)
Guohui Sun, Tengjiao Fan, Xiaodong Sun, Yuxing Hao, Xin Cui, Lijiao Zhao, Ting Ren, Yue Zhou, Rugang Zhong, Yongzhen Peng
In Silico Prediction of O⁶-Methylguanine-DNA Methyltransferase Inhibitory Potency of Base Analogs with QSAR and Machine Learning Methods. Molecules (Basel, Switzerland) 23 (11) (2018)