ACS pharmacology & translational science

Keyphrases

Publications

volume 7, number 8, 2024

Liang Xue, Daniel van Kalken, Erika M James, Giulia Giammo, Matthew T Labenski, Susan Cantin, Kelly Fahnoe, Karin Worm, Zhigang Wang, Alan F Corin
A Probe-Free Occupancy Assay to Assess a Targeted Covalent Inhibitor of Receptor Tyrosine-Protein Kinase erbB-2. ACS pharmacology & translational science 7 (8) (2024)
Georgina B Armstrong, Alan Lewis, Vidhi Shah, Paul Taylor, Craig J Jamieson, Glenn A Burley, William Lewis, Zahra Rattray
A First Insight into the Developability of an Immunoglobulin G3: A Combined Computational and Experimental Approach. ACS pharmacology & translational science 7 (8) (2024)
Andrea Chicca, Daniel Bátora, Christoph Ullmer, Antonello Caruso, Sabine Grüner, Jürgen Fingerle, Thomas Hartung, Roland Degen, Matthias Müller, Uwe Grether, Pal Pacher, Juerg Gertsch
A Highly Potent, Orally Bioavailable Pyrazole-Derived Cannabinoid CB2 Receptor- Selective Full Agonist for In Vivo Studies. ACS pharmacology & translational science 7 (8) (2024)
Chandra Choudhury, James E Egleton, Neville J Butcher, Angela J Russell, Rodney F Minchin
Small Molecule Inhibitors of Arylamine N-Acetyltransferase 1 Attenuate Cellular Respiration. ACS pharmacology & translational science 7 (8) (2024)
Nico Bückreiß, Marie Schulz-Fincke, Philipp König, Marco Maccarana, Toin H van Kuppevelt, Jin-Ping Li, Martin Götte, Gerd Bendas
Epigenetic Targeting of Heparan Sulfate 3- O - and 6- O -Sulfation in Breast Cancer Cells: Prospects for Attenuating Prothrombotic Tumor Cell Activities. ACS pharmacology & translational science 7 (8) (2024)
Kenan Aloss, Pedro Henrique Leroy Viana, Syeda Mahak Zahra Bokhari, Nino Giunashvili, Csaba András Schvarcz, Dániel Bócsi, Zoltán Koós, Zoltán Benyó, Peter Hamar
Ivermectin Synergizes with Modulated Electro-hyperthermia and Improves Its Anticancer Effects in a Triple-Negative Breast Cancer Mouse Model. ACS pharmacology & translational science 7 (8) (2024)
Saja Baraghithy, Asaad Gammal, Anna Permyakova, Sharleen Hamad, Radka Kočvarová, Yael Calles, Joseph Tam
5-Methoxy-2-aminoindane Reverses Diet-Induced Obesity and Improves Metabolic Parameters in Mice: A Potential New Class of Antiobesity Therapeutics. ACS pharmacology & translational science 7 (8) (2024)
Ana Semeano, Rian Garland, Alessandro Bonifazi, Kuo Hao Lee, John Famiglietti, Wenqi Zhang, Yoon Jae Jo, Francisco O Battiti, Lei Shi, Amy Hauck Newman, Hideaki Yano
Linkers in Bitopic Agonists Shape Bias Profile among Transducers for the Dopamine D2 and D3 Receptors. ACS pharmacology & translational science 7 (8) (2024)
Ozlem Ozbek, Destina Ekingen Genc, Kutlu O Ülgen
Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling of Nanomaterials. ACS pharmacology & translational science 7 (8) (2024)
Xin Hu, Paul Shinn, Zina Itkin, Lin Ye, Ya-Qin Zhang, Min Shen, Stephanie Ford-Scheimer, Matthew D Hall
A Comprehensive Collection of Pain and Opioid Use Disorder Compounds for High-Throughput Screening and Artificial Intelligence-Driven Drug Discovery. ACS pharmacology & translational science 7 (8) (2024)
Yi-Hua Chiang, Erin C Berthold, Michelle A Kuntz, Siva Rama Raju Kanumuri, Alexandria S Senetra, Sushobhan Mukhopadhyay, Aidan J Hampson, Christopher R McCurdy, Abhisheak Sharma
Multiple-Dose Pharmacokinetics and Safety of Mitragynine, the Major Alkaloid of Kratom, in Rats. ACS pharmacology & translational science 7 (8) (2024)
Jing Wang, Muqing Zhang, Hu Wang
Emerging Landscape of Mesenchymal Stem Cell Senescence Mechanisms and Implications on Therapeutic Strategies. ACS pharmacology & translational science 7 (8) (2024)
Jindian Li, Xingfang Hong, Yingxi Chen, Bin Yin, Hongzhang Yang, Changrong Shi, Xinying Zeng, Deliang Zhang, Zhide Guo, Xianzhong Zhang
MicroPET Imaging of Riboflavin Transporter 3 Expression in Myocardial Infarction/Reperfusion Rat Models with Radiofluorinated Riboflavin. ACS pharmacology & translational science 7 (8) (2024)
Yu-Fang Hsieh, Kuan-Jiuh Lin
Rapid-Test Kit for Cardiac Troponin I: A Reliable Enzyme-Linked-Immuno-Substrate-Assay-Based Biosensor for Daily-Use Naked-Eye Detection and Pharmacokinetic Studies for Myocardial Infarction in Cardiovascular Disease. ACS pharmacology & translational science 7 (8) (2024)
Nobuki Kazuta, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono
Effect of Linker Entities on Pharmacokinetics of 111 In-Labeled Prostate-Specific Membrane Antigen-Targeting Ligands with an Albumin Binder. ACS pharmacology & translational science 7 (8) (2024)
Jiaqi Huang, Aishik Chakraborty, Lakshmi Suchitra Tadepalli, Arghya Paul
Adoption of a Tetrahedral DNA Nanostructure as a Multifunctional Biomaterial for Drug Delivery. ACS pharmacology & translational science 7 (8) (2024)
Ingrid Marie Heyns, Alina Farah Faunce, Mercy Ngosa Mumba, Naga Venkata Ravi Kumar Majeti, Meenakshi Arora
Nanotechnology-Enhanced Naloxone and Alternative Treatments for Opioid Addiction. ACS pharmacology & translational science 7 (8) (2024)
Tianyi Ding, Abdul-Akim Guseinov, Graeme Milligan, Bianca Plouffe, Irina G Tikhonova
Exploring an Intracellular Allosteric Site of CC-Chemokine Receptor 4 from 3D Models, Probe Simulations, and Mutagenesis. ACS pharmacology & translational science 7 (8) (2024)
Abhay Prakash Mishra, Rajesh Kumar, Seetha Harilal, Manisha Nigam, Deepanjan Datta, Sudarshan Singh
Emerging Landscape of In Vitro Models for Assessing Rheumatoid Arthritis Management. ACS pharmacology & translational science 7 (8) (2024)
Liu Tang, Huiliang Geng, Lei Zhang, Xinyi Wang, Mengdan Fei, Boyuan Yang, Haijie Sun, Zhongli Zhang
In-Depth Characterization for Methionine Oxidization in Complementary Domain Region by Hydrophobic Interaction Chromatography. ACS pharmacology & translational science 7 (8) (2024)
Youyi Peng, Allen H Zhang, Liping Wei, William J Welsh
Preclinical Evaluation of Sigma 1 Receptor Antagonists as a Novel Treatment for Painful Diabetic Neuropathy. ACS pharmacology & translational science 7 (8) (2024)
Abhay Prakash Mishra, Rajesh Kumar, Seetha Harilal, Manisha Nigam, Deepanjan Datta, Sudarshan Singh
Emerging Landscape of In Vitro Models for Assessing Rheumatoid Arthritis Management. ACS pharmacology & translational science 7 (8) (2024)
Nobuki Kazuta, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono
Effect of Linker Entities on Pharmacokinetics of 111 In-Labeled Prostate-Specific Membrane Antigen-Targeting Ligands with an Albumin Binder. ACS pharmacology & translational science 7 (8) (2024)
Yinlong Li, Kenneth Dahl, Peter Johnström, Katarina Varnäs, Lars Farde, Christer Halldin, Amy Medd, Donna Maier, Mark E Powell, Jiahui Chen, Richard Van, Jimmy Patel, Ahmad Chaudhary, Yabiao Gao, Zhendong Song, Ahmed Haider, Yihan Shao, Charles S Elmore, Steven H Liang, Magnus Schou
Radiosynthesis and Evaluation of 11C-Labeled Isoindolone-Based Positive Allosteric Modulators for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor 2. ACS pharmacology & translational science 7 (8) (2024)
Tianyi Ding, Abdul-Akim Guseinov, Graeme Milligan, Bianca Plouffe, Irina G Tikhonova
Exploring an Intracellular Allosteric Site of CC-Chemokine Receptor 4 from 3D Models, Probe Simulations, and Mutagenesis. ACS pharmacology & translational science 7 (8) (2024)

volume 7, number 9, 2024

Mohammad Nasrullah, Remant Bahadur Kc, Kyle Nickel, Kylie Parent, Cezary Kucharski, Daniel Nisakar Meenakshi Sundaram, Amarnath Praphakar Rajendran, Xiaoyan Jiang, Joseph Brandwein, Hasan Uludağ
Lipopolymer/siRNA Nanoparticles Targeting the Signal Transducer and Activator of Transcription 5A Disrupts Proliferation of Acute Lymphoblastic Leukemia. ACS pharmacology & translational science 7 (9) (2024)
Merrill M Froney, Christian R Cook, Alyssa M Cadiz, Katherine A Flinter, Sara T Ledeboer, Bianca Chan, Lauren E Burris, Brian P Hardy, Kenneth H Pearce, Alexis C Wardell, Brian T Golitz, Michael B Jarstfer, Samantha G Pattenden
A First-in-Class High-Throughput Screen to Discover Modulators of the Alternative Lengthening of Telomeres (ALT) Pathway. ACS pharmacology & translational science 7 (9) (2024)
Man-Sha Wu, Ze-Rui Zhou, Xiao-Yuan Wang, Xi-Chen Du, Da-Wei Li, Ruo-Can Qian
Design of a Membrane-Anchored DNAzyme-Based Molecular Machine for Enhanced Cancer Therapy by Customized Cascade Regulation. ACS pharmacology & translational science 7 (9) (2024)
Ying-Ju Lai, Yung-Hsin Yeh, Yen-Lin Huang, Celina De Almeida, Gwo-Jyh Chang, Wei-Jan Chen, Hsao-Hsun Hsu
Empagliflozin Attenuates Pulmonary Arterial Remodeling Through Peroxisome Proliferator-Activated Receptor Gamma Activation. ACS pharmacology & translational science 7 (9) (2024)
Sohui Park, Jisu Shin, Kyeonghwan Kim, Darong Kim, Won Seok Lee, Jusuk Lee, Illhwan Cho, In Wook Park, Soljee Yoon, Songmin Lee, Hye Yun Kim, Ji Hoon Lee, Ki Bum Hong, Young Soo Kim
Modulation of Amyloid and Tau Aggregation to Alleviate Cognitive Impairment in a Transgenic Mouse Model of Alzheimer's Disease. ACS pharmacology & translational science 7 (9) (2024)
Ahmed Kh Abosalha, Paromita Islam, Jacqueline L Boyajian, Rahul Thareja, Sabrina Schaly, Amal Kassab, Stephanie Makhlouf, Sarah Alali, Satya Prakash
Colon-Targeted Sustained-Release Combinatorial 5-Fluorouracil and Quercetin poly(lactic- co -glycolic) Acid (PLGA) Nanoparticles Show Enhanced Apoptosis and Minimal Tumor Drug Resistance for Their Potential Use in Colon Cancer. ACS pharmacology & translational science 7 (9) (2024)
Patrik Oleksak, David Rysanek, Marketa Vancurova, Pavla Vasicova, Alexandra Urbancokova, Josef Novak, Dominika Maurencova, Pavel Kashmel, Jana Houserova, Romana Mikyskova, Ondrej Novotny, Milan Reinis, Pavel Juda, Miroslav Hons, Jirina Kroupova, David Sedlák, Tetyana Sulimenko, Pavel Draber, Marketa Chlubnova, Eugenie Nepovimova, Teodorico C Ramalho, Miroslav Lisa, Rudolf Andrys, Tereza Kobrlova, Ondrej Soukup, Jiri Janousek, Lukas Prchal, Jiri Bartek, Kamil Musilek, Zdenek Hodny
Discovery of a 6-Aminobenzo[ b ]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities. ACS pharmacology & translational science 7 (9) (2024)
Arun Upadhyay, Vibhuti Joshi
The Ubiquitin Tale: Current Strategies and Future Challenges. ACS pharmacology & translational science 7 (9) (2024)
Jolien De Neve, Émile Breault, Santo Previti, Esaü Vangeloven, Bobbi Loranger, Magali Chartier, Rebecca Brouillette, Annik Lanoie, Brian J Holleran, Jean-Michel Longpré, Louis Gendron, Dirk Tourwé, Philippe Sarret, Steven Ballet
Design, Synthesis, and In Vitro Characterization of Proteolytically-Stable Opioid-Neurotensin Hybrid Peptidomimetics. ACS pharmacology & translational science 7 (9) (2024)
Arupam Patra, Arisha Arora, Siddhartha Sankar Ghosh, Gurvinder Kaur Saini
Beauvericin Reverses Epithelial-to-Mesenchymal Transition in Triple-Negative Breast Cancer Cells through Regulation of Notch Signaling and Autophagy. ACS pharmacology & translational science 7 (9) (2024)
Ilaria D'Acquarica, Israel Agranat
Correction to "The Quest for Secondary Pharmaceuticals: Drug Repurposing/Chiral-Switches Combination Strategy". ACS pharmacology & translational science 7 (9) (2024)
Andras Bilkei-Gorzo, Britta Schurmann, Marion Schneider, Michael Kraemer, Prakash Nidadavolu, Eva C Beins, Christa Elisabeth Müller, Mona Dvir-Ginzberg, Andreas Zimmer
Bidirectional Effect of Long-Term Δ 9 -Tetrahydrocannabinol Treatment on mTOR Activity and Metabolome. ACS pharmacology & translational science 7 (9) (2024)
Nicholas A Weirath, Carrie Haskell-Luevano
Recommended Tool Compounds for the Melanocortin Receptor (MCR) G Protein-Coupled Receptors (GPCRs). ACS pharmacology & translational science 7 (9) (2024)
Núria Nadal-Gratacós, Martalu D Pazos, David Pubill, Jorge Camarasa, Elena Escubedo, Xavier Berzosa, Raúl López-Arnau
Structure-Activity Relationship of Synthetic Cathinones: An Updated Review. ACS pharmacology & translational science 7 (9) (2024)
Subham Guin, Akash Ashokan, Alan Pollack, Shanta Dhar
Lipid Metabolism Modulatory Cisplatin Prodrug Sensitizes Resistant Prostate Cancer toward Androgen Deprivation Therapy. ACS pharmacology & translational science 7 (9) (2024)
Megan N Doleschal, Jenna Miller, Sankalp Jain, Alexey V Zakharov, Ganesha Rai, Anton Simeonov, Bolormaa Baljinnyam, Zhihao Zhuang
Cell-Based Covalent-Capture Deubiquitinase Assay for Inhibitor Discovery. ACS pharmacology & translational science 7 (9) (2024)
Moein Ala
Noncoding Ribonucleic Acids (RNAs) May Improve Response to Immunotherapy in Pancreatic Cancer. ACS pharmacology & translational science 7 (9) (2024)
Lucas T Laudermilk, Joel E Schlosburg, Elaine A Gay, Ann M Decker, Aaron Williams, Rubica Runton, Vineetha Vasukuttan, Archana Kotiya, George S Amato, Rangan Maitra
Novel Peripherally Selective Cannabinoid Receptor 1 Neutral Antagonist Improves Metabolic Dysfunction-Associated Steatotic Liver Disease in Mice. ACS pharmacology & translational science 7 (9) (2024)
Nagoor Meeran Mf, Seenipandi Arunachalam, Azimullah Sheikh, Dhanya Saraswathiamma, Alia Albawardi, Saeeda Al Marzooqi, Niraj Kumar Jha, Sandeep Subramanya, Rami Beiram, Shreesh Kumar Ojha
α-Bisabolol: A Dietary Sesquiterpene that Attenuates Apoptotic and Nonapoptotic Cell Death Pathways by Regulating the Mitochondrial Biogenesis and Endoplasmic Reticulum Stress-Hippo Signaling Axis in Doxorubicin-Induced Acute Cardiotoxicity in Rats. ACS pharmacology & translational science 7 (9) (2024)
Ashish Kumar Tripathi, Anirban Sardar, Nikhil Rai, Divya Rai, Aboli Girme, Shradha Sinha, Kunal Chutani, Lal Hingorani, Prabhat Ranjan Mishra, Ritu Trivedi
Withaferin A Ameliorated the Bone Marrow Fat Content in Obese Male Mice by Favoring Osteogenesis in Bone Marrow Mesenchymal Stem Cells and Preserving the Bone Mineral Density. ACS pharmacology & translational science 7 (9) (2024)
Hayder Ridha Salman, Elaf Mahmood Shihab, Hasanain Kamil Hasan, Alaa Hamza Abbas, Shan Mohammed Khorsheed, Salar Ayad Fakhri
Mitigative Effects of Topical Norfloxacin on an Imiquimod-Induced Murine Model of Psoriasis. ACS pharmacology & translational science 7 (9) (2024)
Kathrin Schorr, Xinyu Chen, Takanori Sasaki, Anahi Paula Arias-Loza, Johannes Lang, Takahiro Higuchi, Achim M Goepferich
Rethinking Thin-Layer Chromatography for Screening Technetium-99m Radiolabeled Polymer Nanoparticles. ACS pharmacology & translational science 7 (9) (2024)
Sadhana Sharma, Vincenzo S Gilberto, Cassandra L Levens, Anushree Chatterjee, Kristine A Kuhn, Prashant Nagpal
Microbiome- and Host Inflammasome-Targeting Inhibitor Nanoligomers Are Therapeutic in the Murine Colitis Model. ACS pharmacology & translational science 7 (9) (2024)
Lisa J Gould, Morteza Mahmoudi
Analysis of Biogenic Amines and Small Molecule Metabolites in Human Diabetic Wound Ulcer Exudate. ACS pharmacology & translational science 7 (9) (2024)
Subhasis Roy, Monali Chakrabarti, Trisha Mondal, Tapas Kumar Das, Tonmoy Sarkar, Sebak Datta, Mrinalkanti Kundu, Manish Banerjee, Onkar Prakash Kulkarni
Effect of an Autotaxin Inhibitor, 2-(4-Chlorophenyl)-7-methyl-8-pentylimidazo[1,2- a ] Pyrimidin-5(8 H )-one (CBT-295), on Bile Duct Ligation-Induced Chronic Liver Disease and Associated Hepatic Encephalopathy in Rats. ACS pharmacology & translational science 7 (9) (2024)