Gyorgy Szabadkai

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 12

Top Topics

Low Density Lipoprotein

Kidney Transplantation

Tyrosine Kinase

Endoplasmic Reticulum

Top Venues

Science advances

Cell death and differentiation

Nature communications

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Valeria Pingitore, Jessica Pancholi, Thomas W Hornsby, Justin Warne, Gareth Pryce, Laura J McCormick, Julia Hill, Gauri Bhosale, Jing Peng, Lydia S Newton, Greg J Towers, Simon J Coles, Ah Wing Edith Chan, Michael R Duchen, Gyorgy Szabadkai, David Baker, David L Selwood
Delocalized quinolinium-macrocyclic peptides, an atypical chemotype for CNS penetration. Science advances 10 (28) (2024)
Michela Menegollo, Robert B Bentham, Tiago Henriques, Seow Qi Ng, Ziyu Ren, Clarinde Esculier, Sia Agarwal, Emily T Y Tong, Clement Lo, Sanjana Ilangovan, Zorka Szabadkai, Matteo Suman, Neill Patani, Avinash D Ghanate, Kevin Bryson, Robert C Stein, Mariia O Yuneva, Gyorgy Szabadkai
Multi-State Gene Cluster Switches Determine the Adaptive Mitochondrial And Metabolic Landscape of Breast Cancer. Cancer research (2024)
Valeria Pingitore, Jessica Pancholi, Thomas W Hornsby, Justin Warne, Gareth Pryce, Laura J McCormick, Julia Hill, Gauri Bhosale, Jing Peng, Lydia S Newton, Greg J Towers, Simon J Coles, Ah Wing Edith Chan, Michael R Duchen, Gyorgy Szabadkai, David Baker, David L Selwood
Delocalized quinolinium-macrocyclic peptides, an atypical chemotype for CNS penetration. Science advances 10 (28) (2024)
Chih-Yao Chung, Kritarth Singh, Vassilios N Kotiadis, Gabriel E Valdebenito, Jee Hwan Ahn, Emilie Topley, Joycelyn Tan, William D Andrews, Benoit Bilanges, Robert D S Pitceathly, Gyorgy Szabadkai, Mariia O Yuneva, Michael R Duchen
Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation. Nature communications 12 (1) (2021)
Ruoyan Xu, William Jones, Ewa Wilcz-Villega, Ana Sh Costa, Vinothini Rajeeve, Robert B Bentham, Kevin Bryson, Ai Nagano, Busra Yaman, Sheila Olendo Barasa, Yewei Wang, Claude Chelala, Pedro Cutillas, Gyorgy Szabadkai, Christian Frezza, Katiuscia Bianchi
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism. EMBO reports 21 (9) (2020)
Radha Desai, Daniel A East, Liana Hardy, Danilo Faccenda, Manuel Rigon, James Crosby, María Soledad Alvarez, Aarti Singh, Marta Mainenti, Laura Kuhlman Hussey, Robert Bentham, Gyorgy Szabadkai, Valentina Zappulli, Gurtej K Dhoot, Lisa E Romano, Dong Xia, Isabelle Coppens, Anne Hamacher-Brady, J Paul Chapple, Rosella Abeti, Roland A Fleck, Gema Vizcay-Barrena, Kenneth Smith, Michelangelo Campanella
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response. Science advances 6 (51) (2020)
Ewa Wilcz-Villega, Edward Carter, Alastair Ironside, Ruoyan Xu, Isabella Mataloni, Julie Holdsworth, William Jones, Rocío Moreno Béjar, Lukas Uhlik, Robert B Bentham, Susana A Godinho, Jesmond Dalli, Richard Grose, Gyorgy Szabadkai, Louise Jones, Kairbaan M Hodivala-Dilke, Katiuscia Bianchi
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway. EMBO molecular medicine 12 (2) (2020)
Sukaina Rashid, Marta O Freitas, Danilo Cucchi, Gemma Bridge, Zhi Yao, Laura Gay, Marc Williams, Jun Wang, Nirosha Suraweera, Andrew Silver, Stuart A C McDonald, Claude Chelala, Gyorgy Szabadkai, Sarah A Martin
MLH1 deficiency leads to deregulated mitochondrial metabolism. Cell death & disease 10 (11) (2019)
Nicoletta Plotegher, Dany Perocheau, Ruggero Ferrazza, Giulia Massaro, Gauri Bhosale, Federico Zambon, Ahad A Rahim, Graziano Guella, Simon N Waddington, Gyorgy Szabadkai, Michael R Duchen
Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload. Cell death and differentiation 27 (5) (2019)
Benoit Bilanges, Samira Alliouachene, Wayne Pearce, Daniele Morelli, Gyorgy Szabadkai, Yuen-Li Chung, Gaëtan Chicanne, Colin Valet, Julia M Hill, Peter J Voshol, Lucy Collinson, Christopher Peddie, Khaled Ali, Essam Ghazaly, Vinothini Rajeeve, Georgios Trichas, Shankar Srinivas, Claire Chaussade, Rachel S Salamon, Jonathan M Backer, Cheryl L Scudamore, Maria A Whitehead, Erin P Keaney, Leon O Murphy, Robert K Semple, Bernard Payrastre, Sharon A Tooze, Bart Vanhaesebroeck
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism. Nature communications 8 (1) (2017)
Aikaterini Lampada, James O'Prey, Gyorgy Szabadkai, Kevin M Ryan, Daniel Hochhauser, Paolo Salomoni
mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism. Cell death and differentiation 24 (6) (2017)
Thomas Briston, Malcolm Roberts, Sian Lewis, Ben Powney, James M Staddon, Gyorgy Szabadkai, Michael R Duchen
Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability. Scientific reports 7 (1) (2017)