Michael R Duchen (Michael Duchen, M R Duchen)

Scopus Author ID ResearcherID Loop profile Ciência ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 13

Top Venues

Science advances

Scientific reports

Cell death and differentiation

Nature communications

University College London

University College London (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University College London

United Kingdom

Professor of Physiology :: Cell and Developmental Biology

University College London

United Kingdom

reader :: Physiology

University College London

United Kingdom

Royal Society University Research fellow :: Physiology

University College London

United Kingdom

Royal Society University Research fellow :: Physiology

Education History

University College London

United Kingdom

PHD :: Physiology

Publications

Valeria Pingitore, Jessica Pancholi, Thomas W Hornsby, Justin Warne, Gareth Pryce, Laura J McCormick, Julia Hill, Gauri Bhosale, Jing Peng, Lydia S Newton, Greg J Towers, Simon J Coles, Ah Wing Edith Chan, Michael R Duchen, Gyorgy Szabadkai, David Baker, David L Selwood
Delocalized quinolinium-macrocyclic peptides, an atypical chemotype for CNS penetration. Science advances 10 (28) (2024)
Valeria Pingitore, Jessica Pancholi, Thomas W Hornsby, Justin Warne, Gareth Pryce, Laura J McCormick, Julia Hill, Gauri Bhosale, Jing Peng, Lydia S Newton, Greg J Towers, Simon J Coles, Ah Wing Edith Chan, Michael R Duchen, Gyorgy Szabadkai, David Baker, David L Selwood
Delocalized quinolinium-macrocyclic peptides, an atypical chemotype for CNS penetration. Science advances 10 (28) (2024)
Gabriel E Valdebenito, Anitta R Chacko, Michael R Duchen
The mitochondrial ATP synthase as an ATP consumer-a surprising therapeutic target. The EMBO journal (2023)
Emanuela D'Acunto, Apostolos Papandreou, I Serangeli, M D'Orsi, V Sabato, N A Guadagno, Gauri Bhosale, Silvana Caristi, A V Failla, Antonella De Jaco, Emanuele Cacci, Michael R Duchen, Giuseppe Lupo, Giovanna Galliciotti, Elena Miranda
Polymerogenic neuroserpin causes mitochondrial alterations and activates NFκB but not the UPR in a neuronal model of neurodegeneration FENIB. Cellular and molecular life sciences : CMLS 79 (8) (2022)
Liliana M Almeida, Brígida R Pinho, Michael R Duchen, Jorge M A Oliveira
The PERKs of mitochondria protection during stress: insights for PERK modulation in neurodegenerative and metabolic diseases. Biological reviews of the Cambridge Philosophical Society 97 (5) (2022)
Chih-Yao Chung, Kritarth Singh, Vassilios N Kotiadis, Gabriel E Valdebenito, Jee Hwan Ahn, Emilie Topley, Joycelyn Tan, William D Andrews, Benoit Bilanges, Robert D S Pitceathly, Gyorgy Szabadkai, Mariia O Yuneva, Michael R Duchen
Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation. Nature communications 12 (1) (2021)
Nicoletta Plotegher, Dany Perocheau, Ruggero Ferrazza, Giulia Massaro, Gauri Bhosale, Federico Zambon, Ahad A Rahim, Graziano Guella, Simon N Waddington, Gyorgy Szabadkai, Michael R Duchen
Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload. Cell death and differentiation 27 (5) (2019)
Elizabeth Haythorne, Maria Rohm, Martijn van de Bunt, Melissa F Brereton, Andrei I Tarasov, Thomas S Blacker, Gregor Sachse, Mariana Silva Dos Santos, Raul Terron Exposito, Simon Davis, Otto Baba, Roman Fischer, Michael R Duchen, Patrik Rorsman, James I MacRae, Frances M Ashcroft
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells. Nature communications 10 (1) (2019)
Paromita Majumder, Thomas S Blacker, Lisa S Nolan, Michael R Duchen, Jonathan E Gale
Multiphoton NAD(P)H FLIM reveals metabolic changes in individual cell types of the intact cochlea upon sensorineural hearing loss. Scientific reports 9 (1) (2019)
Martin W Nicholson, Aaron Sweeney, Eva Pekle, Sabina Alam, Afia B Ali, Michael R Duchen, Jasmina N Jovanovic
Diazepam-induced loss of inhibitory synapses mediated by PLCδ/ Ca2+/calcineurin signalling downstream of GABAA receptors. Molecular psychiatry 23 (9) (2018)
Niamh M C Connolly, Pierre Theurey, Vera Adam-Vizi, Nicolas G Bazan, Paolo Bernardi, Juan P Bolaños, Carsten Culmsee, Valina L Dawson, Mohanish Deshmukh, Michael R Duchen, Heiko Düssmann, Gary Fiskum, Maria F Galindo, Giles E Hardingham, J Marie Hardwick, Mika B Jekabsons, Elizabeth A Jonas, Joaquin Jordán, Stuart A Lipton, Giovanni Manfredi, Mark P Mattson, BethAnn McLaughlin, Axel Methner, Anne N Murphy, Michael P Murphy, David G Nicholls, Brian M Polster, Tullio Pozzan, Rosario Rizzuto, Jorgina Satrústegui, Ruth S Slack, Raymond A Swanson, Russell H Swerdlow, Yvonne Will, Zheng Ying, Alvin Joselin, Anna Gioran, Catarina Moreira Pinho, Orla Watters, Manuela Salvucci, Irene Llorente-Folch, David S Park, Daniele Bano, Maria Ankarcrona, Paola Pizzo, Jochen H M Prehn
Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases. Cell death and differentiation 25 (3) (2017)
Thomas Briston, Malcolm Roberts, Sian Lewis, Ben Powney, James M Staddon, Gyorgy Szabadkai, Michael R Duchen
Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability. Scientific reports 7 (1) (2017)
Shunsuke Kon, Kojiro Ishibashi, Hiroto Katoh, Sho Kitamoto, Takanobu Shirai, Shinya Tanaka, Mihoko Kajita, Susumu Ishikawa, Hajime Yamauchi, Yuta Yako, Tomoko Kamasaki, Tomohiro Matsumoto, Hirotaka Watanabe, Riku Egami, Ayana Sasaki, Atsuko Nishikawa, Ikumi Kameda, Takeshi Maruyama, Rika Narumi, Tomoko Morita, Yoshiteru Sasaki, Ryosuke Enoki, Sato Honma, Hiromi Imamura, Masanobu Oshima, Tomoyoshi Soga, Jun-Ichi Miyazaki, Michael R Duchen, Jin-Min Nam, Yasuhito Onodera, Shingo Yoshioka, Junichi Kikuta, Masaru Ishii, Masamichi Imajo, Eisuke Nishida, Yoichiro Fujioka, Yusuke Ohba, Toshiro Sato, Yasuyuki Fujita
Cell competition with normal epithelial cells promotes apical extrusion of transformed cells through metabolic changes. Nature cell biology 19 (5) (2017)

Michael R Duchen.css-eqlu8i{font-size:small;padding-left:4px;} (Michael Duchen, M R Duchen)

Publication Activity (10 Years)

Top Topics

Top Venues

Michael R Duchen (Michael Duchen, M R Duchen)