Gyun Min Lee

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 33

Top Topics

Recombinant Human

Histone Deacetylase

Klebsiella Pneumoniae

Top Venues

Biotechnology and bioengineering

ACS synthetic biology

Biotechnology journal

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Su Hyun Kim, Jong-Ho Park, Sungwook Shin, Seunghyeon Shin, Dahyun Chun, Yeon-Gu Kim, Jiseon Yoo, Weon-Kyoo You, Jae Seong Lee, Gyun Min Lee
Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP-SETDB1 Complex for Enhancing Difficult-to-Express Protein Production. ACS synthetic biology 13 (2) (2024)
Su Hyun Kim, Jong-Ho Park, Sungwook Shin, Seunghyeon Shin, Dahyun Chun, Yeon-Gu Kim, Jiseon Yoo, Weon-Kyoo You, Jae Seong Lee, Gyun Min Lee
Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP-SETDB1 Complex for Enhancing Difficult-to-Express Protein Production. ACS synthetic biology (2024)
Chansik Yoon, Eun-Ji Lee, Dongil Kim, Siyun Joung, Yujin Kim, Heungchae Jung, Yeon-Gu Kim, Gyun Min Lee
SiMPl-GS: Advancing Cell Line Development via Synthetic Selection Marker for Next-Generation Biopharmaceutical Production. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Su Hyun Kim, Jong-Ho Park, Sungwook Shin, Seunghyeon Shin, Dahyun Chun, Yeon-Gu Kim, Jiseon Yoo, Weon-Kyoo You, Jae Seong Lee, Gyun Min Lee
Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP-SETDB1 Complex for Enhancing Difficult-to-Express Protein Production. ACS synthetic biology 13 (2) (2024)
Sungje Park, Seunghyeon Shin, Haeshin Lee, Jae-Hyung Jang, Gyun Min Lee
Enhancing the production of adeno-associated virus (AAV)2 and AAV9 with high full capsid ratio in HEK293 cells through design-of-experiment optimization of triple plasmid ratio. Biotechnology journal 19 (3) (2024)
Sungje Park, Seunghyeon Shin, Haeshin Lee, Jae-Hyung Jang, Gyun Min Lee
Enhancing the production of adeno-associated virus (AAV)2 and AAV9 with high full capsid ratio in HEK293 cells through design-of-experiment optimization of triple plasmid ratio. Biotechnology journal 19 (3) (2024)
Su Hyun Kim, Jong-Ho Park, Sungwook Shin, Seunghyeon Shin, Dahyun Chun, Yeon-Gu Kim, Jiseon Yoo, Weon-Kyoo You, Jae Seong Lee, Gyun Min Lee
Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP-SETDB1 Complex for Enhancing Difficult-to-Express Protein Production. ACS synthetic biology 13 (2) (2024)
Tae Kwang Ha, Andreu Òdena, Karen Julie la Cour Karottki, Che Lin Kim, Hooman Hefzi, Gyun Min Lee, Helene Faustrup Kildegaard, Lars K Nielsen, Lise Marie Grav, Nathan E Lewis
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium. Biotechnology and bioengineering 120 (4) (2023)
Dongil Kim, Su Hyun Kim, Chansik Yoon, Gyun Min Lee
Genome-wide CRISPR/Cas9 knockout screening to mitigate cell growth inhibition induced by histone deacetylase inhibitors in recombinant CHO cells. Biotechnology and bioengineering (2023)
Tae Kwang Ha, Andreu Òdena, Karen Julie la Cour Karottki, Che Lin Kim, Hooman Hefzi, Gyun Min Lee, Helene Faustrup Kildegaard, Lars K Nielsen, Lise Marie Grav, Nathan E Lewis
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium. Biotechnology and bioengineering 120 (4) (2023)
Tae Kwang Ha, Andreu Òdena, Karen Julie la Cour Karottki, Che Lin Kim, Hooman Hefzi, Gyun Min Lee, Helene Faustrup Kildegaard, Lars K Nielsen, Lise Marie Grav, Nathan E Lewis
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium. Biotechnology and bioengineering 120 (4) (2023)
Tae Kwang Ha, Andreu Òdena, Karen Julie la Cour Karottki, Che Lin Kim, Hooman Hefzi, Gyun Min Lee, Helene Faustrup Kildegaard, Lars K Nielsen, Lise Marie Grav, Nathan E Lewis
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium. Biotechnology and bioengineering 120 (4) (2023)
Kyungsoo Kim, Young Sik Kim, Ju Woong Jang, Gyun Min Lee
Enhancing the production of recombinant human TGF-β1 through an understanding of TGF-β1 synthesis, signaling, and endocytosis in CHO cells. Biotechnology journal (2023)
Tae Kwang Ha, Andreu Òdena, Karen Julie la Cour Karottki, Che Lin Kim, Hooman Hefzi, Gyun Min Lee, Helene Faustrup Kildegaard, Lars K Nielsen, Lise Marie Grav, Nathan E Lewis
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium. Biotechnology and bioengineering (2022)
Dongil Kim, Chansik Yoon, Gyun Min Lee
Small molecule epigenetic modulators for enhancing recombinant antibody production in CHO cell cultures. Biotechnology and bioengineering 119 (3) (2022)
Tae Kwang Ha, Andreu Òdena, Karen Julie la Cour Karottki, Che Lin Kim, Hooman Hefzi, Gyun Min Lee, Helene Faustrup Kildegaard, Lars K Nielsen, Lise Marie Grav, Nathan E Lewis
Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium. Biotechnology and bioengineering (2022)
Mi Gyeom Kim, Gyun Min Lee
Blockage of undesirable endocytosis of recombinant human growth/differentiation factor-5 in Chinese hamster ovary cell cultures requires heparin analogs with specific chain lengths. Biotechnology journal 16 (10) (2021)
Seunghyeon Shin, Su Hyun Kim, Jae Seong Lee, Gyun Min Lee
Streamlined Human Cell-Based Recombinase-Mediated Cassette Exchange Platform Enables Multigene Expression for the Production of Therapeutic Proteins. ACS synthetic biology 10 (7) (2021)
Stefan Kol, Daniel Ley, Tune Wulff, Marianne Decker, Johnny Arnsdorf, Sanne Schoffelen, Anders Holmgaard Hansen, Tanja Lyholm Jensen, Jahir M Gutierrez, Austin W T Chiang, Helen O Masson, Bernhard O Palsson, Bjørn G Voldborg, Lasse Ebdrup Pedersen, Helene Faustrup Kildegaard, Gyun Min Lee, Nathan E Lewis
Multiplex secretome engineering enhances recombinant protein production and purity. Nature communications 11 (1) (2020)
Daria Sergeeva, Gyun Min Lee, Lars Keld Nielsen, Lise Marie Grav
Multicopy Targeted Integration for Accelerated Development of High-Producing Chinese Hamster Ovary Cells. ACS synthetic biology 9 (9) (2020)
Seunghyeon Shin, Su Hyun Kim, Sung Wook Shin, Lise Marie Grav, Lasse Ebdrup Pedersen, Jae Seong Lee, Gyun Min Lee
Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells. ACS synthetic biology 9 (6) (2020)
Jahir M Gutierrez, Amir Feizi, Shangzhong Li, Thomas B Kallehauge, Hooman Hefzi, Lise M Grav, Daniel Ley, Deniz Baycin Hizal, Michael J Betenbaugh, Bjorn Voldborg, Helene Faustrup Kildegaard, Gyun Min Lee, Bernhard O Palsson, Jens B Nielsen, Nathan E Lewis
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion. Nature communications 11 (1) (2020)
Sang Yoon Lee, Minhye Baek, Gyun Min Lee
Comprehensive characterization of dihydrofolate reductase-mediated gene amplification for the establishment of recombinant human embryonic kidney 293 cells producing monoclonal antibodies. Biotechnology journal 16 (5) (2020)
Kai Xiong, Kim Fabiano Marquart, Karen Julie la Cour Karottki, Shangzhong Li, Isaac Shamie, Jae Seong Lee, Signe Gerling, Nan Cher Yeo, Alejandro Chavez, Gyun Min Lee, Nathan E Lewis, Helene Faustrup Kildegaard
Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference. Biotechnology and bioengineering 116 (7) (2019)
Jong Hyun Lee, Jihoon Kim, Jong-Ho Park, Won Do Heo, Gyun Min Lee
Analysis of Golgi pH in Chinese hamster ovary cells using ratiometric pH-sensitive fluorescent proteins. Biotechnology and bioengineering 116 (5) (2019)
Tae Kwang Ha, Anders H Hansen, Helene F Kildegaard, Gyun Min Lee
BiP Inducer X: An ER Stress Inhibitor for Enhancing Recombinant Antibody Production in CHO Cell Culture. Biotechnology journal 14 (10) (2019)
Karen Julie la Cour Karottki, Hooman Hefzi, Kai Xiong, Isaac Shamie, Anders Holmgaard Hansen, Songyuan Li, Lasse Ebdrup Pedersen, Shangzhong Li, Jae Seong Lee, Gyun Min Lee, Helene Faustrup Kildegaard, Nathan E Lewis
Awakening dormant glycosyltransferases in CHO cells with CRISPRa. Biotechnology and bioengineering 117 (2) (2019)
Soo Min Noh, Seunghyeon Shin, Gyun Min Lee
Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies. Scientific reports 8 (1) (2018)
Che Lin Kim, Mi Yeong Jung, Young Sik Kim, Ju Woong Jang, Gyun Min Lee
Improving the production of recombinant human bone morphogenetic protein-4 in Chinese hamster ovary cell cultures by inhibition of undesirable endocytosis. Biotechnology and bioengineering 115 (10) (2018)
Eric Baek, Jae Seong Lee, Gyun Min Lee
Untangling the mechanism of 3-methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3-methyladenine. Biotechnology and bioengineering 115 (9) (2018)
Da Young Yu, Sang Yoon Lee, Gyun Min Lee
Glutamine synthetase gene knockout-human embryonic kidney 293E cells for stable production of monoclonal antibodies. Biotechnology and bioengineering 115 (5) (2018)
Jong Hyun Lee, Yeong Ran Jeong, Yeon-Gu Kim, Gyun Min Lee
Understanding of decreased sialylation of Fc-fusion protein in hyperosmotic recombinant Chinese hamster ovary cell culture: N-glycosylation gene expression and N-linked glycan antennary profile. Biotechnology and bioengineering 114 (8) (2017)
Jin Hyoung Park, Jong Hwa Jin, In Jung Ji, Hyun Joo An, Jong Won Kim, Gyun Min Lee
Proteomic analysis of host cell protein dynamics in the supernatant of Fc-fusion protein-producing CHO DG44 and DUKX-B11 cell lines in batch and fed-batch cultures. Biotechnology and bioengineering 114 (10) (2017)