Lars Keld Nielsen (Lars K Nielsen, Lars Nielsen)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 43

Top Topics

Trauma Patients

Escherichia Coli

Gas Chromatography Mass Spectrometry

Top Venues

Biotechnology and bioengineering

ACS synthetic biology

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Teddy Groves, Nicholas Luke Cowie, Lars Keld Nielsen
Bayesian Regression Facilitates Quantitative Modeling of Cell Metabolism. ACS synthetic biology 13 (4) (2024)
Teddy Groves, Nicholas Luke Cowie, Lars Keld Nielsen
Bayesian Regression Facilitates Quantitative Modeling of Cell Metabolism. ACS synthetic biology 13 (4) (2024)
Teddy Groves, Nicholas Luke Cowie, Lars Keld Nielsen
Bayesian Regression Facilitates Quantitative Modeling of Cell Metabolism. ACS synthetic biology (2024)
Fernando Silva-Lance, Isabel Montejano-Montelongo, Eric Bautista, Lars Keld Nielsen, Pär Ingemar Johansson, Igor Marin de Mas
Integrating Genome-Scale Metabolic Models with Patient Plasma Metabolome to Study Endothelial Metabolism In Situ. International journal of molecular sciences 25 (10) (2024)
Jorge Carrasco, Nicholas Cowie, Shannara Taylor Parkins, Marjan Mansouvar, Teddy Groves, Lars Keld Nielsen
Shu: visualization of high-dimensional biological pathways. Bioinformatics (Oxford, England) 40 (3) (2024)
Fernando Silva-Lance, Isabel Montejano-Montelongo, Eric Bautista, Lars Keld Nielsen, Pär Ingemar Johansson, Igor Marin de Mas
Integrating Genome-Scale Metabolic Models with Patient Plasma Metabolome to Study Endothelial Metabolism In Situ. International journal of molecular sciences 25 (10) (2024)
Teddy Groves, Nicholas Luke Cowie, Lars Keld Nielsen
Bayesian Regression Facilitates Quantitative Modeling of Cell Metabolism. ACS synthetic biology 13 (4) (2024)
Teddy Groves, Nicholas Luke Cowie, Lars Keld Nielsen
Bayesian Regression Facilitates Quantitative Modeling of Cell Metabolism. ACS synthetic biology (2024)
Teddy Groves, Nicholas Luke Cowie, Lars Keld Nielsen
Bayesian Regression Facilitates Quantitative Modeling of Cell Metabolism. ACS synthetic biology 13 (4) (2024)
Teddy Groves, Nicholas Luke Cowie, Lars Keld Nielsen
Bayesian Regression Facilitates Quantitative Modeling of Cell Metabolism. ACS synthetic biology 13 (4) (2024)
Stefano Donati, Matthias Mattanovich, Pernille Hjort, Simo Abdessamad Baallal Jacobsen, Sarah Dina Blomquist, Drude Mangaard, Nicolas Gurdo, Felix Pacheco Pastor, Jérôme Maury, René Hanke, Markus J Herrgård, Tune Wulff, Tadas Jakočiūnas, Lars Keld Nielsen, Douglas McCloskey
An automated workflow for multi-omics screening of microbial model organisms. NPJ systems biology and applications 9 (1) (2023)
Enrico Orsi, Pablo Iván Nikel, Lars Keld Nielsen, Stefano Donati
Synergistic investigation of natural and synthetic C1-trophic microorganisms to foster a circular carbon economy. Nature communications 14 (1) (2023)
Igor Marin de Mas, Helena Herand, Jorge Carrasco, Lars Keld Nielsen, Pär Ingemar Johansson
A Protocol for the Automatic Construction of Highly Curated Genome-Scale Models of Human Metabolism. Bioengineering (Basel, Switzerland) 10 (5) (2023)
Hanne H Henriksen, Igor Marín de Mas, Lars Keld Nielsen, Joseph Krocker, Jakob Stensballe, Sigurður T Karvelsson, Niels H Secher, Óttar Rolfsson, Charles E Wade, Pär Ingemar Johansson
Endothelial Cell Phenotypes Demonstrate Different Metabolic Patterns and Predict Mortality in Trauma Patients. International journal of molecular sciences 24 (3) (2023)
Carmen Bedia, Nuria Dalmau, Lars Keld Nielsen, Romà Tauler, Igor Marín de Mas
A Multi-Level Systems Biology Analysis of Aldrin's Metabolic Effects on Prostate Cancer Cells. Proteomes 11 (2) (2023)
Matthias Nöbel, Craig P Barry, Michael A MacDonald, Kym Baker, Evan Shave, Stephen M Mahler, Trent P Munro, Verónica S Martínez, Lars Keld Nielsen, Esteban Marcellin
Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation. Biotechnology and bioengineering (2023)
Carmen Bedia, Nuria Dalmau, Lars Keld Nielsen, Romà Tauler, Igor Marín de Mas
A Multi-Level Systems Biology Analysis of Aldrin's Metabolic Effects on Prostate Cancer Cells. Proteomes 11 (2) (2023)
Carmen Bedia, Nuria Dalmau, Lars Keld Nielsen, Romà Tauler, Igor Marín de Mas
A Multi-Level Systems Biology Analysis of Aldrin's Metabolic Effects on Prostate Cancer Cells. Proteomes 11 (2) (2023)
Stefano Donati, Matthias Mattanovich, Pernille Hjort, Simo Abdessamad Baallal Jacobsen, Sarah Dina Blomquist, Drude Mangaard, Nicolas Gurdo, Felix Pacheco Pastor, Jérôme Maury, René Hanke, Markus J Herrgård, Tune Wulff, Tadas Jakočiūnas, Lars Keld Nielsen, Douglas McCloskey
An automated workflow for multi-omics screening of microbial model organisms. NPJ systems biology and applications 9 (1) (2023)
Stefano Donati, Matthias Mattanovich, Pernille Hjort, Simo Abdessamad Baallal Jacobsen, Sarah Dina Blomquist, Drude Mangaard, Nicolas Gurdo, Felix Pacheco Pastor, Jérôme Maury, René Hanke, Markus J Herrgård, Tune Wulff, Tadas Jakočiūnas, Lars Keld Nielsen, Douglas McCloskey
An automated workflow for multi-omics screening of microbial model organisms. NPJ systems biology and applications 9 (1) (2023)
Hanne H Henriksen, Igor Marín de Mas, Lars Keld Nielsen, Joseph Krocker, Jakob Stensballe, Sigurður T Karvelsson, Niels H Secher, Óttar Rolfsson, Charles E Wade, Pär Ingemar Johansson
Endothelial Cell Phenotypes Demonstrate Different Metabolic Patterns and Predict Mortality in Trauma Patients. International journal of molecular sciences 24 (3) (2023)
Carmen Bedia, Nuria Dalmau, Lars Keld Nielsen, Romà Tauler, Igor Marín de Mas
A Multi-Level Systems Biology Analysis of Aldrin's Metabolic Effects on Prostate Cancer Cells. Proteomes 11 (2) (2023)
Hanne H Henriksen, Igor Marín de Mas, Lars Keld Nielsen, Joseph Krocker, Jakob Stensballe, Sigurður T Karvelsson, Niels H Secher, Óttar Rolfsson, Charles E Wade, Pär Ingemar Johansson
Endothelial Cell Phenotypes Demonstrate Different Metabolic Patterns and Predict Mortality in Trauma Patients. International journal of molecular sciences 24 (3) (2023)
Carmen Bedia, Nuria Dalmau, Lars Keld Nielsen, Romà Tauler, Igor Marín de Mas
A Multi-Level Systems Biology Analysis of Aldrin's Metabolic Effects on Prostate Cancer Cells. Proteomes 11 (2) (2023)
Craig P Barry, Rosemary Gillane, Gert H Talbo, Manual Plan, Robin Palfreyman, Andrea K Haber-Stuk, John Power, Lars Keld Nielsen, Esteban Marcellin
Multi-omic characterisation of Streptomyces hygroscopicus NRRL 30439: detailed assessment of its secondary metabolic potential. Molecular omics 18 (3) (2022)
Marta R A Matos, Pedro A Saa, Nicholas Cowie, Svetlana Volkova, Marina de Leeuw, Lars Keld Nielsen
GRASP: a computational platform for building kinetic models of cellular metabolism. Bioinformatics advances 2 (1) (2022)
Marta R A Matos, Pedro A Saa, Nicholas Cowie, Svetlana Volkova, Marina de Leeuw, Lars Keld Nielsen
GRASP: a computational platform for building kinetic models of cellular metabolism. Bioinformatics advances 2 (1) (2022)
Verónica S Martínez, Pedro A Saa, Jason Jooste, Kanupriya Tiwari, Lake-Ee Quek, Lars Keld Nielsen
The topology of genome-scale metabolic reconstructions unravels independent modules and high network flexibility. PLoS computational biology 18 (6) (2022)
Iván Martínez-Monge, Carlos Martínez, Marianne Decker, Isuru A Udugama, Igor Marín de Mas, Krist V Gernaey, Lars Keld Nielsen
Soft-sensors application for automated feeding control in high-throughput mammalian cell cultures. Biotechnology and bioengineering 119 (4) (2022)
Michael A MacDonald, Craig P Barry, Teddy Groves, Verónica S Martínez, Peter P Gray, Kym Baker, Evan Shave, Stephen Mahler, Trent Munro, Esteban Marcellin, Lars Keld Nielsen
Modeling apoptosis resistance in CHO cells with CRISPR-mediated knockouts of Bak1, Bax, and Bok. Biotechnology and bioengineering 119 (6) (2022)
Svetlana Kutuzova, Pasquale Colaianni, Shubham Gupta, Timo Sachsenberg, Oliver Alka, Oliver Kohlbacher, Bo Burla, Federico Torta, Lars Schrübbers, Mette Kristensen, Lars Keld Nielsen, Markus J Herrgård, Douglas McCloskey
SmartPeak Automates Targeted and Quantitative Metabolomics Data Processing. Analytical chemistry 92 (24) (2020)
Daria Sergeeva, Gyun Min Lee, Lars Keld Nielsen, Lise Marie Grav
Multicopy Targeted Integration for Accelerated Development of High-Producing Chinese Hamster Ovary Cells. ACS synthetic biology 9 (9) (2020)
Mareike Bongers, Jordi Perez-Gil, Mark P Hodson, Lars Schrübbers, Tune Wulff, Morten Oa Sommer, Lars Keld Nielsen, Claudia E Vickers
Adaptation of hydroxymethylbutenyl diphosphate reductase enables volatile isoprenoid production. eLife 9 (2020)
Tim McCubbin, R Axayacatl Gonzalez-Garcia, Robin W Palfreyman, Chris Stowers, Lars Keld Nielsen, Esteban Marcellin
A Pan-Genome Guided Metabolic Network Reconstruction of Five Propionibacterium Species Reveals Extensive Metabolic Diversity. Genes 11 (10) (2020)
Camila A Orellana, Verónica S Martínez, Michael A MacDonald, Matthew N Henry, Marianne Gillard, Peter P Gray, Lars Keld Nielsen, Stephen Mahler, Esteban Marcellin
'Omics driven discoveries of gene targets for apoptosis attenuation in CHO cells. Biotechnology and bioengineering 118 (1) (2020)
Christian Lieven, Moritz Emanuel Beber, Brett G Olivier, Frank T Bergmann, Meric Ataman, Parizad Babaei, Jennifer A Bartell, Lars M Blank, Siddharth Chauhan, Kevin Correia, Christian Diener, Andreas Dräger, Birgitta E Ebert, Janaka N Edirisinghe, José P Faria, Adam M Feist, Georgios Fengos, Ronan M T Fleming, Beatriz García-Jiménez, Vassily Hatzimanikatis, Wout van Helvoirt, Christopher S Henry, Henning Hermjakob, Markus J Herrgård, Ali Kaafarani, Hyun Uk Kim, Zachary A King, Steffen Klamt, Edda Klipp, Jasper J Koehorst, Matthias König, Meiyappan Lakshmanan, Dong-Yup Lee, Sang Yup Lee, Sunjae Lee, Nathan E Lewis, Filipe Liu, Hongwu Ma, Daniel Machado, Radhakrishnan Mahadevan, Paulo Maia, Adil Mardinglu, Gregory L Medlock, Jonathan M Monk, Jens B Nielsen, Lars Keld Nielsen, Juan Nogales, Intawat Nookaew, Bernhard O Palsson, Jason A Papin, Kiran Raosaheb Patil, Mark G Poolman, Nathan D Price, Osbaldo Resendis-Antonio, Anne Richelle, Isabel Rocha, Benjamín J Sánchez, Peter J Schaap, Rahuman S Malik Sheriff, Saeed Shoaie, Nikolaus Sonnenschein, Bas Teusink, Paulo Vilaça, Jon Olav Vik, Judith A H Wodke, Joana C Xavier, Qianqian Yuan, Maksim Zakhartsev, Cheng Zhang
MEMOTE for standardized genome-scale metabolic model testing. Nature biotechnology 38 (3) (2020)
Matthew N Henry, Michael A MacDonald, Camila A Orellana, Peter P Gray, Marianne Gillard, Kym Baker, Lars Keld Nielsen, Esteban Marcellin, Stephen Mahler, Verónica S Martínez
Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production. Biotechnology and bioengineering 117 (4) (2020)
Ricardo A Gonzalez-Garcia, Timothy McCubbin, Mark S Turner, Lars Keld Nielsen, Esteban Marcellin
Engineering Escherichia coli for propionic acid production through the Wood-Werkman cycle. Biotechnology and bioengineering 117 (1) (2019)
Jorge Alonso-Gutierrez, Daisuke Koma, Qijun Hu, Yuchen Yang, Leanne J G Chan, Christopher J Petzold, Paul D Adams, Claudia E Vickers, Lars Keld Nielsen, Jay D Keasling, Taek Soon Lee
Toward industrial production of isoprenoids in Escherichia coli: Lessons learned from CRISPR-Cas9 based optimization of a chromosomally integrated mevalonate pathway. Biotechnology and bioengineering 115 (4) (2018)
Camila A Orellana, Esteban Marcellin, Robin W Palfreyman, Trent P Munro, Peter P Gray, Lars Keld Nielsen
RNA-Seq Highlights High Clonal Variation in Monoclonal Antibody Producing CHO Cells. Biotechnology journal 13 (3) (2018)
Maria Buchsteiner, Lake-Ee Quek, Peter Gray, Lars Keld Nielsen
Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect. Biotechnology and bioengineering 115 (9) (2018)
Simon A Hardwick, Wendy Y Chen, Ted Wong, Ira W Deveson, James Blackburn, Stacey B Andersen, Lars Keld Nielsen, John S Mattick, Tim R Mercer
Spliced synthetic genes as internal controls in RNA sequencing experiments. Nature methods 13 (9) (2016)
Ira W Deveson, Wendy Y Chen, Ted Wong, Simon A Hardwick, Stacey B Andersen, Lars Keld Nielsen, John S Mattick, Tim R Mercer
Representing genetic variation with synthetic DNA standards. Nature methods 13 (9) (2016)
Michael B Clark, Tim R Mercer, Giovanni Bussotti, Tommaso Leonardi, Katelin R Haynes, Joanna Crawford, Marion E Brunck, Kim-Anh Lê Cao, Gethin P Thomas, Wendy Y Chen, Ryan J Taft, Lars Keld Nielsen, Anton J Enright, John S Mattick, Marcel E Dinger
Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing. Nature methods 12 (4) (2015)
Tim R Mercer, Michael B Clark, Joanna Crawford, Marion E Brunck, Daniel J Gerhardt, Ryan J Taft, Lars Keld Nielsen, Marcel E Dinger, John S Mattick
Targeted sequencing for gene discovery and quantification using RNA CaptureSeq. Nature protocols 9 (5) (2014)