Haoliang Yuan

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 30

Top Topics

Antiplatelet Therapy

High Efficiency

Top Venues

Journal of medicinal chemistry

Journal of chemical information and modeling

The Journal of organic chemistry

Organic letters

This page only lists publications with an associated author ORCID identifier.

Publications

Gang Sun, Shi-Ping Zhan, Yi-Feng Zhao, Xingyi Du, Mao-Ying Shi, Jing Li, Haoliang Yuan, Xiaoan Wen, Hong-Bin Sun, Qing-Long Xu
Organophosphorus-Catalyzed Direct Dehydroxylative Thioetherification of Alcohols with Hypervalent Organosulfur Compounds. The Journal of organic chemistry (2024)
Liu Liu, Honghan Zhang, Jie Hou, Yuying Zhang, Luosen Wang, Shijun Wang, Zhiying Yao, Tao Xie, Xiaoan Wen, Qing-Long Xu, Liang Dai, Zhiqi Feng, Pu Zhang, Yaojun Wu, Hong-Bin Sun, Jun Liu, Haoliang Yuan
Discovery of Novel PD-L1 Small-Molecular Inhibitors with Potent In Vivo Anti-tumor Immune Activity. Journal of medicinal chemistry (2024)
Gang Sun, Yi-Han Yu, Han Kai, Fan-Ying Meng, Haoliang Yuan, Xiaoan Wen, Liu Liu, Qing-Long Xu
P III /P V -Catalyzed Beckmann Reaction and Sequential [2,3]-Sigmatropic Rearrangement to Construct 2-Amidopyridines. Organic letters 26 (17) (2024)
Panpan Chen, Cai Chen, Yizheng Zheng, Fangjun Chen, Zhaojun Liu, Shenhong Ren, Hangyu Song, Tongdan Liu, Zhipeng Lu, Hong-Bin Sun, Yi Kong, Haoliang Yuan
Discovery of 2,3-Dihydro[1,4]dioxino[2,3- g ]benzofuran Derivatives as Protease Activated Receptor 4 (PAR4) Antagonists with Potent Antiplatelet Aggregation Activity and Low Bleeding Tendency. Journal of medicinal chemistry 67 (7) (2024)
Gang Sun, Yi-Han Yu, Han Kai, Fan-Ying Meng, Haoliang Yuan, Xiaoan Wen, Liu Liu, Qing-Long Xu
P III /P V -Catalyzed Beckmann Reaction and Sequential [2,3]-Sigmatropic Rearrangement to Construct 2-Amidopyridines. Organic letters (2024)
Luosen Wang, Jie Hou, Peng Cao, Zhiying Yao, Shijun Wang, Yuying Zhang, Sheng Wang, Haoliang Yuan, Liu Liu
Design, Synthesis, and Biological Evaluation of Chroman Derivatives as PD-1/PD-L1 Antagonists. Journal of chemical information and modeling 64 (12) (2024)
Luosen Wang, Jie Hou, Peng Cao, Zhiying Yao, Shijun Wang, Yuying Zhang, Sheng Wang, Haoliang Yuan, Liu Liu
Design, Synthesis, and Biological Evaluation of Chroman Derivatives as PD-1/PD-L1 Antagonists. Journal of chemical information and modeling 64 (12) (2024)
Liu Liu, Honghan Zhang, Jie Hou, Yuying Zhang, Luosen Wang, Shijun Wang, Zhiying Yao, Tao Xie, Xiaoan Wen, Qing-Long Xu, Liang Dai, Zhiqi Feng, Pu Zhang, Yaojun Wu, Hong-Bin Sun, Jun Liu, Haoliang Yuan
Discovery of Novel PD-L1 Small-Molecular Inhibitors with Potent In Vivo Anti-tumor Immune Activity. Journal of medicinal chemistry 67 (6) (2024)
Panpan Chen, Cai Chen, Yizheng Zheng, Fangjun Chen, Zhaojun Liu, Shenhong Ren, Hangyu Song, Tongdan Liu, Zhipeng Lu, Hong-Bin Sun, Yi Kong, Haoliang Yuan
Discovery of 2,3-Dihydro[1,4]dioxino[2,3- g ]benzofuran Derivatives as Protease Activated Receptor 4 (PAR4) Antagonists with Potent Antiplatelet Aggregation Activity and Low Bleeding Tendency. Journal of medicinal chemistry (2024)
Yi-Han Yu, Gang Sun, Di Zhao, Yi-Kai Wu, Haoliang Yuan, Xiaoan Wen, Liu Liu, Qing-Long Xu
Synthesis of C(3) SCF 3 -Substituted Pyrrolidinoindoline by P III /P V Redox Catalysis Using CF 3 SO 2 Cl as Electrophilic CF 3 S Reagent. The Journal of organic chemistry (2024)
Luosen Wang, Jie Hou, Peng Cao, Zhiying Yao, Shijun Wang, Yuying Zhang, Sheng Wang, Haoliang Yuan, Liu Liu
Design, Synthesis, and Biological Evaluation of Chroman Derivatives as PD-1/PD-L1 Antagonists. Journal of chemical information and modeling (2024)
Liu Liu, Honghan Zhang, Jie Hou, Yuying Zhang, Luosen Wang, Shijun Wang, Zhiying Yao, Tao Xie, Xiaoan Wen, Qing-Long Xu, Liang Dai, Zhiqi Feng, Pu Zhang, Yaojun Wu, Hong-Bin Sun, Jun Liu, Haoliang Yuan
Discovery of Novel PD-L1 Small-Molecular Inhibitors with Potent In Vivo Anti-tumor Immune Activity. Journal of medicinal chemistry 67 (6) (2024)
Gang Sun, Shi-Ping Zhan, Yi-Feng Zhao, Xingyi Du, Mao-Ying Shi, Jing Li, Haoliang Yuan, Xiaoan Wen, Hong-Bin Sun, Qing-Long Xu
Organophosphorus-Catalyzed Direct Dehydroxylative Thioetherification of Alcohols with Hypervalent Organosulfur Compounds. The Journal of organic chemistry 89 (2) (2024)
Panpan Chen, Cai Chen, Yizheng Zheng, Fangjun Chen, Zhaojun Liu, Shenhong Ren, Hangyu Song, Tongdan Liu, Zhipeng Lu, Hong-Bin Sun, Yi Kong, Haoliang Yuan
Discovery of 2,3-Dihydro[1,4]dioxino[2,3- g ]benzofuran Derivatives as Protease Activated Receptor 4 (PAR4) Antagonists with Potent Antiplatelet Aggregation Activity and Low Bleeding Tendency. Journal of medicinal chemistry 67 (7) (2024)
Yi-Han Yu, Gang Sun, Di Zhao, Yi-Kai Wu, Haoliang Yuan, Xiaoan Wen, Liu Liu, Qing-Long Xu
Synthesis of C(3) SCF 3 -Substituted Pyrrolidinoindoline by P III /P V Redox Catalysis Using CF 3 SO 2 Cl as Electrophilic CF 3 S Reagent. The Journal of organic chemistry 89 (16) (2024)
Shihe Hu, Yu Liu, Jiye Ma, Weijie Ding, Hua Chen, Haifang Jiang, Hongxing Chen, Song Wei, Yonggao Liu, Qiao-Mei Jin, Haoliang Yuan, Libo Yan
Discovery and Structural Optimization of Novel Quinolone Derivatives as Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors. Journal of medicinal chemistry (2023)
Zhiqi Feng, Jiehao Xiang, Gang Sun, Hui Liu, Yanyan Wang, Xin Liu, Jin Feng, Qing-Long Xu, Xiaoan Wen, Haoliang Yuan, Hong-Bin Sun, Liang Dai
Discovery of the First Subnanomolar PPARα/δ Dual Agonist for the Treatment of Cholestatic Liver Diseases. Journal of medicinal chemistry (2023)
Kai-Wen Hu, Xiao You, Xiaoan Wen, Haoliang Yuan, Qing-Long Xu, Zengwei Lai
Synthesis of Functionalized Thiazolidin-2-imine and Oxazolidin-2-one Derivatives from p -Quinamines via [3 + 2] Annulation of Isothiocyanates and CO 2 . The Journal of organic chemistry (2022)
Xing Li, Shanlin Yang, Honghan Zhang, Xipeng Liu, Yuchen Gao, Yuqi Chen, Liu Liu, Dalin Wang, Zijiang Liang, Shengjie Liu, Liang Dai, Qing-Long Xu, Haoliang Yuan, Caiping Chen, Hong-Bin Sun, Xiaoan Wen
Discovery of Orally Bioavailable N -Benzylpiperidinol Derivatives as Potent and Selective USP7 Inhibitors with In Vivo Antitumor Immunity Activity against Colon Cancer. Journal of medicinal chemistry (2022)
Yongjun Zang, Luyang Tai, Yuanyang Hu, Yu Wang, Hong-Bin Sun, Xiaoan Wen, Haoliang Yuan, Liang Dai
Discovery of a Novel Macrocyclic ATP Citrate Lyase Inhibitor. Journal of chemical information and modeling 62 (12) (2022)
Zhiqi Feng, Jiehao Xiang, Hui Liu, Jiaxin Li, Xiangrui Xu, Gang Sun, Runan Zheng, Shangran Zhang, Junlong Liu, Shanlin Yang, Qing-Long Xu, Xiaoan Wen, Haoliang Yuan, Hong-Bin Sun, Liang Dai
Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPARα/δ Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis. Journal of medicinal chemistry 65 (3) (2022)
Liu Liu, Zhiying Yao, Shijun Wang, Tao Xie, Guoqing Wu, Honghan Zhang, Pu Zhang, Yaojun Wu, Haoliang Yuan, Hong-Bin Sun
Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[c][1,2,5]oxadiazole Derivatives as Potent PD-L1 Inhibitors with In Vivo Antitumor Activity. Journal of medicinal chemistry 64 (12) (2021)
Hengzhi Sun, Jinzheng Wang, Shengjie Liu, Xinyu Zhou, Liang Dai, Caiping Chen, Qing-Long Xu, Xiaoan Wen, Ke-Guang Cheng, Hong-Bin Sun, Haoliang Yuan
Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction. Journal of chemical information and modeling 61 (10) (2021)
Liang Dai, Zhiqi Feng, Rili Zha, Keguang Cheng, Xiaoan Wen, Hong-Bin Sun, Haoliang Yuan
Discovery of Novel Peroxisome Proliferator-Activated Receptor α (PPARα) Agonists by Virtual Screening and Biological Evaluation. Journal of chemical information and modeling 60 (3) (2020)
Shengjie Liu, Xinyu Zhou, Minglei Li, Wenfeng Zhao, Shuxi Zhou, Ke-Guang Cheng, Qing-Long Xu, Caiping Chen, Xiaoan Wen, Hong-Bin Sun, Haoliang Yuan
Discovery of Ubiquitin-Specific Protease 7 (USP7) Inhibitors with Novel Scaffold Structures by Virtual Screening, Molecular Dynamics Simulation, and Biological Evaluation. Journal of chemical information and modeling 60 (6) (2020)
Xiangying Zhang, Hong-Bin Sun, Xiaoan Wen, Haoliang Yuan
A Selectivity Study of FFAR4/FFAR1 Agonists by Molecular Modeling. Journal of chemical information and modeling 59 (10) (2019)
Zhangjian Huang, Jianbing Wu, Yu Zou, Haoliang Yuan, Yinqiu Zhang, Yue Fei, Atul Bhardwaj, Jatinder Kaur, Edward E Knaus, Yihua Zhang
Glutathione S-Transferase π-Activatable O2-(Sulfonylethyl Derived) Diazeniumdiolates Potently Suppress Melanoma in Vitro and in Vivo. Journal of medicinal chemistry 61 (5) (2018)
Meixi Hao, Siyuan Hou, Lingjing Xue, Haoliang Yuan, Lulu Zhu, Cong Wang, Bin Wang, Chunming Tang, Can Zhang
Further Developments of the Phenyl-Pyrrolyl Pentane Series of Nonsteroidal Vitamin D Receptor Modulators as Anticancer Agents. Journal of medicinal chemistry 61 (7) (2018)
Yue Wang, Yan-Le Zhi, Qiaomei Jin, Shuai Lu, Guowu Lin, Haoliang Yuan, Taotao Yang, Zhanwei Wang, Chao Yao, Jun Ling, Hao Guo, Tonghui Li, Jianlin Jin, Baoquan Li, Li Zhang, Yadong Chen, Tao Lu
Discovery of 4-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrazole-3-carboxamide (FN-1501), an FLT3- and CDK-Kinase Inhibitor with Potentially High Efficiency against Acute Myelocytic Leukemia. Journal of medicinal chemistry 61 (4) (2018)
Le Zhen, Liang Dai, Xiaoan Wen, Lan Yao, Xiaoliang Jin, Xiao-Wen Yang, Wenfeng Zhao, Sheng-Qi Yu, Haoliang Yuan, Guangji Wang, Hong-Bin Sun
Discovery of Novel Nucleotide Prodrugs with Improved Potency Against HCV Variants Carrying NS5B S282T Mutation. Journal of medicinal chemistry 60 (14) (2017)