Hartmut Kühn (Hartmut Kuhn)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Topics

Structural Basis

Angiotensin Converting Enzyme

Top Venues

International journal of molecular sciences

Virology journal

Antioxidants (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Christian M Zobel, Hartmut Kühn, Maximilian Schreiner, Werner Wenzel, Jasper Wendtland, Cengiz Goekeri, Lorenz Scheit, Klaas Oltmanns, Dominic Rauschning, Marica Grossegesse, Natalie Hofmann, Hubert Wirtz, Sebastian Spethmann, null null
Impact of ACE I gene insertion/deletion, A-240T polymorphisms and the renin-angiotensin-aldosterone system on COVID-19 disease. Virology journal 21 (1) (2024)
Christian M Zobel, Hartmut Kühn, Maximilian Schreiner, Werner Wenzel, Jasper Wendtland, Cengiz Goekeri, Lorenz Scheit, Klaas Oltmanns, Dominic Rauschning, Marica Grossegesse, Natalie Hofmann, Hubert Wirtz, Sebastian Spethmann, null null
Impact of ACE I gene insertion/deletion, A-240T polymorphisms and the renin-angiotensin-aldosterone system on COVID-19 disease. Virology journal 21 (1) (2024)
Parisa Faraji, Astrid Borchert, Shahin Ahmadian, Hartmut Kühn
Butylated Hydroxytoluene (BHT) Protects SH-SY5Y Neuroblastoma Cells from Ferroptotic Cell Death: Insights from In Vitro and In Vivo Studies. Antioxidants (Basel, Switzerland) 13 (2) (2024)
Christian M Zobel, Hartmut Kühn, Maximilian Schreiner, Werner Wenzel, Jasper Wendtland, Cengiz Goekeri, Lorenz Scheit, Klaas Oltmanns, Dominic Rauschning, Marica Grossegesse, Natalie Hofmann, Hubert Wirtz, Sebastian Spethmann, null null
Impact of ACE I gene insertion/deletion, A-240T polymorphisms and the renin-angiotensin-aldosterone system on COVID-19 disease. Virology journal 21 (1) (2024)
Christian M Zobel, Hartmut Kühn, Maximilian Schreiner, Werner Wenzel, Jasper Wendtland, Cengiz Goekeri, Lorenz Scheit, Klaas Oltmanns, Dominic Rauschning, Marica Grossegesse, Natalie Hofmann, Hubert Wirtz, Sebastian Spethmann, null null
Impact of ACE I gene insertion/deletion, A-240T polymorphisms and the renin-angiotensin-aldosterone system on COVID-19 disease. Virology journal 21 (1) (2024)
Christian M Zobel, Hartmut Kühn, Maximilian Schreiner, Werner Wenzel, Jasper Wendtland, Cengiz Goekeri, Lorenz Scheit, Klaas Oltmanns, Dominic Rauschning, Marica Grossegesse, Natalie Hofmann, Hubert Wirtz, Sebastian Spethmann, null null
Impact of ACE I gene insertion/deletion, A-240T polymorphisms and the renin-angiotensin-aldosterone system on COVID-19 disease. Virology journal 21 (1) (2024)
Parisa Faraji, Astrid Borchert, Shahin Ahmadian, Hartmut Kühn
Butylated Hydroxytoluene (BHT) Protects SH-SY5Y Neuroblastoma Cells from Ferroptotic Cell Death: Insights from In Vitro and In Vivo Studies. Antioxidants (Basel, Switzerland) 13 (2) (2024)
Dagmar Heydeck, Christoph Ufer, Kumar R Kakularam, Michael Rothe, Thomas Liehr, Philippe Poulain, Hartmut Kühn
Functional Characterization of Transgenic Mice Overexpressing Human 15-Lipoxygenase-1 (ALOX15) under the Control of the aP2 Promoter. International journal of molecular sciences 24 (5) (2023)
Marjann Schäfer, Florian Reisch, Dominika Labuz, Halina Machelska, Sabine Stehling, Gerhard P Püschel, Michael Rothe, Dagmar Heydeck, Hartmut Kühn
Humanization of the Reaction Specificity of Mouse Alox15b Inversely Modified the Susceptibility of Corresponding Knock-In Mice in Two Different Animal Inflammation Models. International journal of molecular sciences 24 (13) (2023)
Alexander Zhuravlev, Alejandro Cruz, Vladislav Aksenov, Alexey Golovanov, José M Lluch, Hartmut Kühn, Àngels González-Lafont, Igor Ivanov
Different Structures-Similar Effect: Do Substituted 5-(4-Methoxyphenyl)-1 H -indoles and 5-(4-Methoxyphenyl)-1 H -imidazoles Represent a Common Pharmacophore for Substrate Selective Inhibition of Linoleate Oxygenase Activity of ALOX15? Molecules (Basel, Switzerland) 28 (14) (2023)
Kumar R Kakularam, Miquel Canyelles-Niño, Xin Chen, José M Lluch, Àngels González-Lafont, Hartmut Kühn
Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities. International journal of molecular sciences 24 (12) (2023)
Kumar R Kakularam, Miquel Canyelles-Niño, Xin Chen, José M Lluch, Àngels González-Lafont, Hartmut Kühn
Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities. International journal of molecular sciences 24 (12) (2023)
Florian Reisch, Dagmar Heydeck, Marjann Schäfer, Michael Rothe, Jiaxing Yang, Sabine Stehling, Gerhard P Püschel, Hartmut Kühn
Knock-in mice expressing a humanized arachidonic acid 15-lipoxygenase (Alox15) carry a partly dysfunctional erythropoietic system. Cellular & molecular biology letters 28 (1) (2023)
Sophie Roigas, Kumar R Kakularam, Michael Rothe, Dagmar Heydeck, Polamarasetty Aparoy, Hartmut Kühn
Bony Fish Arachidonic Acid 15-Lipoxygenases Exhibit Different Catalytic Properties than Their Mammalian Orthologs, Suggesting Functional Enzyme Evolution during Vertebrate Development. International journal of molecular sciences 24 (18) (2023)
Kumar R Kakularam, Miquel Canyelles-Niño, Xin Chen, José M Lluch, Àngels González-Lafont, Hartmut Kühn
Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities. International journal of molecular sciences 24 (12) (2023)
Dagmar Heydeck, Christoph Ufer, Kumar R Kakularam, Michael Rothe, Thomas Liehr, Philippe Poulain, Hartmut Kühn
Functional Characterization of Transgenic Mice Overexpressing Human 15-Lipoxygenase-1 (ALOX15) under the Control of the aP2 Promoter. International journal of molecular sciences 24 (5) (2023)
Dagmar Heydeck, Christoph Ufer, Kumar R Kakularam, Michael Rothe, Thomas Liehr, Philippe Poulain, Hartmut Kühn
Functional Characterization of Transgenic Mice Overexpressing Human 15-Lipoxygenase-1 (ALOX15) under the Control of the aP2 Promoter. International journal of molecular sciences 24 (5) (2023)
Mariana Soria-Tiedemann, Geert Michel, Iris Urban, Maceler Aldrovandi, Valerie B O'Donnell, Sabine Stehling, Hartmut Kühn, Astrid Borchert
Unbalanced Expression of Glutathione Peroxidase 4 and Arachidonate 15-Lipoxygenase Affects Acrosome Reaction and In Vitro Fertilization. International journal of molecular sciences 23 (17) (2022)
Marjann Schäfer, Kumar R Kakularam, Florian Reisch, Michael Rothe, Sabine Stehling, Dagmar Heydeck, Gerhard P Püschel, Hartmut Kühn
Male Knock-in Mice Expressing an Arachidonic Acid Lipoxygenase 15B (Alox15B) with Humanized Reaction Specificity Are Prematurely Growth Arrested When Aging. Biomedicines 10 (6) (2022)
Sophie Roigas, Dagmar Heydeck, Hartmut Kühn
Functional Characterization of Novel Bony Fish Lipoxygenase Isoforms and Their Possible Involvement in Inflammation. International journal of molecular sciences 23 (24) (2022)
Sophie Roigas, Dagmar Heydeck, Hartmut Kühn
Functional Characterization of Novel Bony Fish Lipoxygenase Isoforms and Their Possible Involvement in Inflammation. International journal of molecular sciences 23 (24) (2022)
Sophie Roigas, Dagmar Heydeck, Hartmut Kühn
Functional Characterization of Novel Bony Fish Lipoxygenase Isoforms and Their Possible Involvement in Inflammation. International journal of molecular sciences 23 (24) (2022)
Sophie Roigas, Dagmar Heydeck, Hartmut Kühn
Functional Characterization of Novel Bony Fish Lipoxygenase Isoforms and Their Possible Involvement in Inflammation. International journal of molecular sciences 23 (24) (2022)
Sophie Roigas, Dagmar Heydeck, Hartmut Kühn
Functional Characterization of Novel Bony Fish Lipoxygenase Isoforms and Their Possible Involvement in Inflammation. International journal of molecular sciences 23 (24) (2022)
Igor Ivanov, Alejandro Cruz, Alexander Zhuravlev, Almerinda Di Venere, Eleonora Nicolai, Sabine Stehling, José M Lluch, Àngels González-Lafont, Hartmut Kühn
Conformational Heterogeneity and Cooperative Effects of Mammalian ALOX15. International journal of molecular sciences 22 (6) (2021)
Eugenia Marbach-Breitrück, Nadine Rohwer, Carmen Infante-Duarte, Silvina Romero-Suarez, Dominika Labuz, Halina Machelska, Laura Kutzner, Nils Helge Schebb, Michael Rothe, Pallu Reddanna, Karsten-Henrich Weylandt, Lothar H Wieler, Dagmar Heydeck, Hartmut Kühn
Knock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported Alox5-/- Mice. Metabolites 11 (10) (2021)
Marlena Rademacher, Hartmut Kühn, Astrid Borchert
Expression Silencing of Glutathione Peroxidase 4 in Mouse Erythroleukemia Cells Delays In Vitro Erythropoiesis. International journal of molecular sciences 22 (15) (2021)
Florian Reisch, Kumar Reddy Kakularam, Sabine Stehling, Dagmar Heydeck, Hartmut Kühn
Eicosanoid biosynthesis in marine mammals. The FEBS journal 288 (4) (2020)
Patricia Saura, Ilya Kaganer, Dagmar Heydeck, José M Lluch, Hartmut Kühn, Àngels González-Lafont
Mutagenesis of Sequence Determinants of Truncated Porcine ALOX15 Induces Changes in the Reaction Specificity by Altering the Catalytic Mechanism of Initial Hydrogen Abstraction. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (4) (2017)
Patricia Saura, Laura Masgrau, Dagmar Heydeck, Hartmut Kühn, José M Lluch, Àngels González-Lafont
Is Regioselectivity in the Enzyme-Catalyzed Hydroperoxidation of Arachidonic Acid Necessarily Determined by Hydrogen Abstraction? The Case of Rabbit Leu597Ala/Ile663Ala ALOX15 Mutant. Chemphyschem : a European journal of chemical physics and physical chemistry 17 (20) (2016)