José M Lluch

ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 25

Top Topics

Crystal Structure

Molecular Dynamics

Top Venues

International journal of molecular sciences

Nature communications

Physical chemistry chemical physics : PCCP

Chemphyschem : a European journal of chemical physics and physical chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Alexander Zhuravlev, Alejandro Cruz, Vladislav Aksenov, Alexey Golovanov, José M Lluch, Hartmut Kühn, Àngels González-Lafont, Igor Ivanov
Different Structures-Similar Effect: Do Substituted 5-(4-Methoxyphenyl)-1 H -indoles and 5-(4-Methoxyphenyl)-1 H -imidazoles Represent a Common Pharmacophore for Substrate Selective Inhibition of Linoleate Oxygenase Activity of ALOX15? Molecules (Basel, Switzerland) 28 (14) (2023)
Kumar R Kakularam, Miquel Canyelles-Niño, Xin Chen, José M Lluch, Àngels González-Lafont, Hartmut Kühn
Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities. International journal of molecular sciences 24 (12) (2023)
Kumar R Kakularam, Miquel Canyelles-Niño, Xin Chen, José M Lluch, Àngels González-Lafont, Hartmut Kühn
Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities. International journal of molecular sciences 24 (12) (2023)
Kumar R Kakularam, Miquel Canyelles-Niño, Xin Chen, José M Lluch, Àngels González-Lafont, Hartmut Kühn
Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities. International journal of molecular sciences 24 (12) (2023)
Miquel Canyelles-Niño, Àngels González-Lafont, José M Lluch
Hydroperoxidation of Docosahexaenoic Acid by Human ALOX12 and pigALOX15-mini-LOX. International journal of molecular sciences 24 (7) (2023)
Miquel Moreno, José M Lluch, Ricard Gelabert
On the Computational Design of Azobenzene-Based Multi-State Photoswitches. International journal of molecular sciences 23 (15) (2022)
Alexey Golovanov, Alexander Zhuravlev, Alejandro Cruz, Vladislav Aksenov, Rania Shafiullina, Kumar R Kakularam, José M Lluch, Hartmut Kuhn, Àngels González-Lafont, Igor Ivanov
N -Substituted 5-(1 H -Indol-2-yl)-2-methoxyanilines Are Allosteric Inhibitors of the Linoleate Oxygenase Activity of Selected Mammalian ALOX15 Orthologs: Mechanism of Action. Journal of medicinal chemistry 65 (3) (2022)
Anna Cebrián-Prats, Alexandre V Pinto, Àngels González-Lafont, Pedro Alexandrino Fernandes, José M Lluch
The role of acetylated cyclooxygenase-2 in the biosynthesis of resolvin precursors derived from eicosapentaenoic acid. Organic & biomolecular chemistry 20 (6) (2022)
Mireia Garcia-Viloca, Jose Ramón Bayascas, José M Lluch, Àngels González-Lafont
Molecular Insights into the Regulation of 3-Phosphoinositide-Dependent Protein Kinase 1: Modeling the Interaction between the Kinase and the Pleckstrin Homology Domains. ACS omega 7 (29) (2022)
Miquel Canyelles-Niño, Àngels González-Lafont, José M Lluch
Theoretical Characterization of the Step-by-Step Mechanism of Conversion of Leukotriene A 4 to Leukotriene B 4 Catalysed by the Enzyme Leukotriene A 4 Hydrolase. International journal of molecular sciences 23 (6) (2022)
Ricard Gelabert, Miquel Moreno, José M Lluch
Predicting the Electronic Absorption Band Shape of Azobenzene Photoswitches. International journal of molecular sciences 24 (1) (2022)
Ricard Gelabert, Miquel Moreno, José M Lluch
Predicting the Electronic Absorption Band Shape of Azobenzene Photoswitches. International journal of molecular sciences 24 (1) (2022)
Ricard Gelabert, Miquel Moreno, José M Lluch
Predicting the Electronic Absorption Band Shape of Azobenzene Photoswitches. International journal of molecular sciences 24 (1) (2022)
Igor Ivanov, Alejandro Cruz, Alexander Zhuravlev, Almerinda Di Venere, Eleonora Nicolai, Sabine Stehling, José M Lluch, Àngels González-Lafont, Hartmut Kühn
Conformational Heterogeneity and Cooperative Effects of Mammalian ALOX15. International journal of molecular sciences 22 (6) (2021)
Sonia Romero-Téllez, Alejandro Cruz, Laura Masgrau, Àngels González-Lafont, José M Lluch
Accounting for the instantaneous disorder in the enzyme-substrate Michaelis complex to calculate the Gibbs free energy barrier of an enzyme reaction. Physical chemistry chemical physics : PCCP 23 (23) (2021)
Alejandro Cruz, Àngels González-Lafont, José M Lluch
Deciphering the Molecular Details of the Lipoxin Formation Mechanism in the 5(S),15(S)-DiHpETE Biosynthetic Pathway Catalyzed by Reticulocyte 15-Lipoxygenase-1. The journal of physical chemistry. B 124 (50) (2020)
Adrián Suñer-Rubio, Anna Cebrián-Prats, Àngels González-Lafont, José M Lluch
Unraveling how the Gly526Ser mutation arrests prostaglandin formation from arachidonic acid catalyzed by cyclooxygenase-2: a combined molecular dynamics and QM/MM study. RSC advances 10 (2) (2020)
Miquel Moreno, Ricard Gelabert, José M Lluch
Deciphering the grounds of the suitability of acylhydrazones as efficient photoswitches. Physical chemistry chemical physics : PCCP 21 (29) (2019)
Victor A Streltsov, Sukanya Luang, Alys Peisley, Joseph N Varghese, James R Ketudat Cairns, Sebastien Fort, Marcel Hijnen, Igor Tvaroška, Ana Ardá, Jesús Jiménez-Barbero, Mercedes Alfonso-Prieto, Carme Rovira, Fernanda Mendoza, Laura Tiessler-Sala, José-Emilio Sánchez-Aparicio, Jaime Rodríguez-Guerra Pedregal, José M Lluch, Jean-Didier Maréchal, Laura Masgrau, Maria Hrmova
Discovery of processive catalysis by an exo-hydrolase with a pocket-shaped active site. Nature communications 10 (1) (2019)
Igor Ivanov, Alexey B Golovanov, Cristián Ferretti, Miquel Canyelles-Niño, Dagmar Heydeck, Sabine Stehling, José M Lluch, Àngels González-Lafont, Hartmut Kühn
Mutations of Triad Determinants Changes the Substrate Alignment at the Catalytic Center of Human ALOX5. ACS chemical biology 14 (12) (2019)
Gisela Cabré, Aida Garrido-Charles, Miquel Moreno, Miquel Bosch, Montserrat Porta-de-la-Riva, Michael Krieg, Marta Gascón-Moya, Núria Camarero, Ricard Gelabert, José M Lluch, Félix Busqué, Jordi Hernando, Pau Gorostiza, Ramon Alibés
Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation. Nature communications 10 (1) (2019)
Gisela Cabré, Aida Garrido-Charles, Àngels González-Lafont, Widukind Moormann, Daniel Langbehn, David Egea, José M Lluch, Rainer Herges, Ramon Alibés, Félix Busqué, Pau Gorostiza, Jordi Hernando
Synthetic Photoswitchable Neurotransmitters Based on Bridged Azobenzenes. Organic letters 21 (10) (2019)
Anna Cebrián-Prats, Tiffani Rovira, Patricia Saura, Àngels González-Lafont, José M Lluch
Inhibition of Mammalian 15-Lipoxygenase by Three Ebselen-like Drugs. A QM/MM and MM/PBSA Comparative Study. The journal of physical chemistry. A 121 (51) (2017)
Patricia Saura, Ilya Kaganer, Dagmar Heydeck, José M Lluch, Hartmut Kühn, Àngels González-Lafont
Mutagenesis of Sequence Determinants of Truncated Porcine ALOX15 Induces Changes in the Reaction Specificity by Altering the Catalytic Mechanism of Initial Hydrogen Abstraction. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (4) (2017)
Patricia Saura, Laura Masgrau, Dagmar Heydeck, Hartmut Kühn, José M Lluch, Àngels González-Lafont
Is Regioselectivity in the Enzyme-Catalyzed Hydroperoxidation of Arachidonic Acid Necessarily Determined by Hydrogen Abstraction? The Case of Rabbit Leu597Ala/Ile663Ala ALOX15 Mutant. Chemphyschem : a European journal of chemical physics and physical chemistry 17 (20) (2016)