Hayk Davtyan

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 29

Top Venues

The Journal of experimental medicine

Nature communications

International journal of molecular sciences

Vaccines

University of California Irvine

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California Irvine Aug 01 2018

United States

Associate Reserach Professor :: Institute for Memory Impairments & Neurological Disorders

University of California Irvine Feb 01 2017 - Jul 31 2018

United States

Associate Project Scientist :: Institute for Memory Impairments & Neurological Disorders

Publications

Armine Hovakimyan, Garri Chilingaryan, Olga King, Joia Kai Capocchi, Jean Paul Chadarevian, Hayk Davtyan, Roman Kniazev, Michael G Agadjanyan, Anahit Ghochikyan
mRNA Vaccine for Alzheimer's Disease: Pilot Study. Vaccines 12 (6) (2024)
Tatevik Antonyan, Garri Chilingaryan, Karen Zagorski, Manush Ghazaryan, Armine Hovakimyan, Hayk Davtyan, Irina Petrushina, Olga King, Roman Kniazev, Nikolai Petrovsky, Anahit Ghochikyan
MultiTEP-Based Vaccines Targeting SARS-CoV-2 Spike Protein IgG Epitopes Elicit Robust Binding Antibody Titers with Limited Virus-Neutralizing Activity. Pathogens (Basel, Switzerland) 13 (6) (2024)
Neta Rosenzweig, Kilian L Kleemann, Thomas Rust, Madison Carpenter, Madeline Grucci, Michael Aronchik, Nieske Brouwer, Isabel Valenbreder, Joya Cooper-Hohn, Malvika Iyer, Rajesh K Krishnan, Kisha N Sivanathan, Wesley Brandão, Taha Yahya, Ana Durao, Zhuoran Yin, Jean Paul Chadarevian, Michael J Properzi, Roni Nowarski, Hayk Davtyan, Howard L Weiner, Mathew Blurton Jones, Hyun-Sik Yang, Bart J L Eggen, Reisa A Sperling, Oleg Butovsky
Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease. Nature medicine (2024)
Tatevik Antonyan, Garri Chilingaryan, Karen Zagorski, Manush Ghazaryan, Armine Hovakimyan, Hayk Davtyan, Irina Petrushina, Olga King, Roman Kniazev, Nikolai Petrovsky, Anahit Ghochikyan
MultiTEP-Based Vaccines Targeting SARS-CoV-2 Spike Protein IgG Epitopes Elicit Robust Binding Antibody Titers with Limited Virus-Neutralizing Activity. Pathogens (Basel, Switzerland) 13 (6) (2024)
Armine Hovakimyan, Garri Chilingaryan, Olga King, Joia Kai Capocchi, Jean Paul Chadarevian, Hayk Davtyan, Roman Kniazev, Michael G Agadjanyan, Anahit Ghochikyan
mRNA Vaccine for Alzheimer's Disease: Pilot Study. Vaccines 12 (6) (2024)
Neta Rosenzweig, Kilian L Kleemann, Thomas Rust, Madison Carpenter, Madeline Grucci, Michael Aronchik, Nieske Brouwer, Isabel Valenbreder, Joya Cooper-Hohn, Malvika Iyer, Rajesh K Krishnan, Kisha N Sivanathan, Wesley Brandão, Taha Yahya, Ana Durao, Zhuoran Yin, Jean Paul Chadarevian, Michael J Properzi, Roni Nowarski, Hayk Davtyan, Howard L Weiner, Mathew Blurton Jones, Hyun-Sik Yang, Bart J L Eggen, Reisa A Sperling, Oleg Butovsky
Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease. Nature medicine (2024)
Tatevik Antonyan, Garri Chilingaryan, Karen Zagorski, Manush Ghazaryan, Armine Hovakimyan, Hayk Davtyan, Irina Petrushina, Olga King, Roman Kniazev, Nikolai Petrovsky, Anahit Ghochikyan
MultiTEP-Based Vaccines Targeting SARS-CoV-2 Spike Protein IgG Epitopes Elicit Robust Binding Antibody Titers with Limited Virus-Neutralizing Activity. Pathogens (Basel, Switzerland) 13 (6) (2024)
Neta Rosenzweig, Kilian L Kleemann, Thomas Rust, Madison Carpenter, Madeline Grucci, Michael Aronchik, Nieske Brouwer, Isabel Valenbreder, Joya Cooper-Hohn, Malvika Iyer, Rajesh K Krishnan, Kisha N Sivanathan, Wesley Brandão, Taha Yahya, Ana Durao, Zhuoran Yin, Jean Paul Chadarevian, Michael J Properzi, Roni Nowarski, Hayk Davtyan, Howard L Weiner, Mathew Blurton Jones, Hyun-Sik Yang, Bart J L Eggen, Reisa A Sperling, Oleg Butovsky
Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease. Nature medicine (2024)
Armine Hovakimyan, Garri Chilingaryan, Olga King, Joia Kai Capocchi, Jean Paul Chadarevian, Hayk Davtyan, Roman Kniazev, Michael G Agadjanyan, Anahit Ghochikyan
mRNA Vaccine for Alzheimer's Disease: Pilot Study. Vaccines 12 (6) (2024)
Karen Zagorski, Olga King, Armine Hovakimyan, Irina Petrushina, Tatevik Antonyan, Gor Chailyan, Manush Ghazaryan, Krzysztof L Hyrc, Jean Paul Chadarevian, Hayk Davtyan, Mathew Blurton Jones, David H Cribbs, Michael G Agadjanyan, Anahit Ghochikyan
Novel Vaccine against Pathological Pyroglutamate-Modified Amyloid Beta for Prevention of Alzheimer's Disease. International journal of molecular sciences 24 (12) (2023)
Karen Zagorski, Olga King, Armine Hovakimyan, Irina Petrushina, Tatevik Antonyan, Gor Chailyan, Manush Ghazaryan, Krzysztof L Hyrc, Jean Paul Chadarevian, Hayk Davtyan, Mathew Blurton Jones, David H Cribbs, Michael G Agadjanyan, Anahit Ghochikyan
Novel Vaccine against Pathological Pyroglutamate-Modified Amyloid Beta for Prevention of Alzheimer's Disease. International journal of molecular sciences 24 (12) (2023)
Karen Zagorski, Olga King, Armine Hovakimyan, Irina Petrushina, Tatevik Antonyan, Gor Chailyan, Manush Ghazaryan, Krzysztof L Hyrc, Jean Paul Chadarevian, Hayk Davtyan, Mathew Blurton Jones, David H Cribbs, Michael G Agadjanyan, Anahit Ghochikyan
Novel Vaccine against Pathological Pyroglutamate-Modified Amyloid Beta for Prevention of Alzheimer's Disease. International journal of molecular sciences 24 (12) (2023)
Amanda McQuade, You Jung Kang, Jonathan Hasselmann, Amit Jairaman, Alexandra Sotelo, Morgan Coburn, Sepideh Kiani Shabestari, Jean Paul Chadarevian, Gianna Fote, Christina H Tu, Emma Danhash, Jorge Silva, Eric Martinez, Carl Cotman, G Aleph Prieto, Leslie M Thompson, Joan S Steffan, Ian F Smith, Hayk Davtyan, Michael Cahalan, Hyung-Ryong Kim, Mathew Blurton Jones
Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature communications 14 (1) (2023)
Amanda McQuade, You Jung Kang, Jonathan Hasselmann, Amit Jairaman, Alexandra Sotelo, Morgan Coburn, Sepideh Kiani Shabestari, Jean Paul Chadarevian, Gianna Fote, Christina H Tu, Emma Danhash, Jorge Silva, Eric Martinez, Carl Cotman, G Aleph Prieto, Leslie M Thompson, Joan S Steffan, Ian F Smith, Hayk Davtyan, Michael Cahalan, Hyung-Ryong Kim, Mathew Blurton Jones
Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature communications 14 (1) (2023)
Changyoun Kim, Armine Hovakimyan, Karen Zagorski, Tatevik Antonyan, Irina Petrushina, Hayk Davtyan, Gor Chailyan, Jonathan Hasselmann, Michiyo Iba, Anthony Adame, Edward Rockenstein, Marcell P Szabo, Mathew Blurton Jones, David H Cribbs, Anahit Ghochikyan, Eliezer Masliah, Michael G Agadjanyan
Author Correction: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. NPJ vaccines 8 (1) (2023)
Jean Paul Chadarevian, Sonia I Lombroso, Graham C Peet, Jonathan Hasselmann, Christina Tu, Dave E Marzan, Joia Capocchi, Freddy S Purnell, Kelsey M Nemec, Alina Lahian, Adrian Escobar, Whitney E England, Sai Chaluvadi, Carleigh A O'Brien, Fazeela Yaqoob, William H Aisenberg, Matias Porras-Paniagua, Mariko L Bennett, Hayk Davtyan, Robert C Spitale, Mathew Blurton Jones, F Christian Bennett
Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. The Journal of experimental medicine 220 (3) (2022)
Changyoun Kim, Armine Hovakimyan, Karen Zagorski, Tatevik Antonyan, Irina Petrushina, Hayk Davtyan, Gor Chailyan, Jonathan Hasselmann, Michiyo Iba, Anthony Adame, Edward Rockenstein, Marcell P Szabo, Mathew Blurton Jones, David H Cribbs, Anahit Ghochikyan, Eliezer Masliah, Michael G Agadjanyan
Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies. NPJ vaccines 7 (1) (2022)
Jean Paul Chadarevian, Sonia I Lombroso, Graham C Peet, Jonathan Hasselmann, Christina Tu, Dave E Marzan, Joia Capocchi, Freddy S Purnell, Kelsey M Nemec, Alina Lahian, Adrian Escobar, Whitney E England, Sai Chaluvadi, Carleigh A O'Brien, Fazeela Yaqoob, William H Aisenberg, Matias Porras-Paniagua, Mariko L Bennett, Hayk Davtyan, Robert C Spitale, Mathew Blurton Jones, F Christian Bennett
Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. The Journal of experimental medicine 220 (3) (2022)
Karen Zagorski, Gor Chailyan, Armine Hovakimyan, Tatevik Antonyan, Sepideh Kiani Shabestari, Irina Petrushina, Hayk Davtyan, David H Cribbs, Mathew Blurton-Jones, Eliezer Masliah, Michael G Agadjanyan, Anahit Ghochikyan
Immunogenicity of MultiTEP-Platform-Based Recombinant Protein Vaccine, PV-1950R, Targeting Three B-Cell Antigenic Determinants of Pathological α-Synuclein. International journal of molecular sciences 23 (11) (2022)
Jean Paul Chadarevian, Sonia I Lombroso, Graham C Peet, Jonathan Hasselmann, Christina Tu, Dave E Marzan, Joia Capocchi, Freddy S Purnell, Kelsey M Nemec, Alina Lahian, Adrian Escobar, Whitney E England, Sai Chaluvadi, Carleigh A O'Brien, Fazeela Yaqoob, William H Aisenberg, Matias Porras-Paniagua, Mariko L Bennett, Hayk Davtyan, Robert C Spitale, Mathew Blurton Jones, F Christian Bennett
Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. The Journal of experimental medicine 220 (3) (2022)
Jean Paul Chadarevian, Sonia I Lombroso, Graham C Peet, Jonathan Hasselmann, Christina Tu, Dave E Marzan, Joia Capocchi, Freddy S Purnell, Kelsey M Nemec, Alina Lahian, Adrian Escobar, Whitney E England, Sai Chaluvadi, Carleigh A O'Brien, Fazeela Yaqoob, William H Aisenberg, Matias Porras-Paniagua, Mariko L Bennett, Hayk Davtyan, Robert C Spitale, Mathew Blurton Jones, F Christian Bennett
Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. The Journal of experimental medicine 220 (3) (2022)
Jean Paul Chadarevian, Sonia I Lombroso, Graham C Peet, Jonathan Hasselmann, Christina Tu, Dave E Marzan, Joia Capocchi, Freddy S Purnell, Kelsey M Nemec, Alina Lahian, Adrian Escobar, Whitney E England, Sai Chaluvadi, Carleigh A O'Brien, Fazeela Yaqoob, William H Aisenberg, Matias Porras-Paniagua, Mariko L Bennett, Hayk Davtyan, Robert C Spitale, Mathew Blurton Jones, F Christian Bennett
Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. The Journal of experimental medicine 220 (3) (2022)
Jean Paul Chadarevian, Sonia I Lombroso, Graham C Peet, Jonathan Hasselmann, Christina Tu, Dave E Marzan, Joia Capocchi, Freddy S Purnell, Kelsey M Nemec, Alina Lahian, Adrian Escobar, Whitney E England, Sai Chaluvadi, Carleigh A O'Brien, Fazeela Yaqoob, William H Aisenberg, Matias Porras-Paniagua, Mariko L Bennett, Hayk Davtyan, Robert C Spitale, Mathew Blurton Jones, F Christian Bennett
Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. The Journal of experimental medicine 220 (3) (2022)
Jean Paul Chadarevian, Sonia I Lombroso, Graham C Peet, Jonathan Hasselmann, Christina Tu, Dave E Marzan, Joia Capocchi, Freddy S Purnell, Kelsey M Nemec, Alina Lahian, Adrian Escobar, Whitney E England, Sai Chaluvadi, Carleigh A O'Brien, Fazeela Yaqoob, William H Aisenberg, Matias Porras-Paniagua, Mariko L Bennett, Hayk Davtyan, Robert C Spitale, Mathew Blurton Jones, F Christian Bennett
Engineering an inhibitor-resistant human CSF1R variant for microglia replacement. The Journal of experimental medicine 220 (3) (2022)
Mohammadreza Mohammadi, Samuel Mathew Rodriguez, Jennifer Cam Luong, Shiri Li, Rui Cao, Hamad Alshetaiwi, Hien Lau, Hayk Davtyan, Mathew Blurton Jones, Mahtab Jafari, Kai Kessenbrock, S Armando Villalta, Paul de Vos, Weian Zhao, Jonathan R T Lakey
Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation. Communications biology 4 (1) (2021)
Amanda McQuade, You Jung Kang, Jonathan Hasselmann, Amit Jairaman, Alexandra Sotelo, Morgan Coburn, Sepideh Kiani Shabestari, Jean Paul Chadarevian, Gianna Fote, Christina H Tu, Emma Danhash, Jorge Silva, Eric Martinez, Carl Cotman, G Aleph Prieto, Leslie M Thompson, Joan S Steffan, Ian F Smith, Hayk Davtyan, Michael Cahalan, Hyung-Ryong Kim, Mathew Blurton Jones
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature communications 11 (1) (2020)
Armine Hovakimyan, Tatevik Antonyan, Sepideh Kiani Shabestari, Olga Svystun, Gor Chailyan, Morgan A Coburn, William Carlen-Jones, Irina Petrushina, Jean Paul Chadarevian, Karen Zagorski, Nikolai Petrovsky, David H Cribbs, Michael G Agadjanyan, Anahit Ghochikyan, Hayk Davtyan
A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice. Scientific reports 9 (1) (2019)
Hayk Davtyan, Armine Hovakimyan, Sepideh Kiani Shabestari, Tatevik Antonyan, Morgan A Coburn, Karen Zagorski, Gor Chailyan, Irina Petrushina, Olga Svystun, Emma Danhash, Nikolai Petrovsky, David H Cribbs, Michael G Agadjanyan, Mathew Blurton-Jones, Anahit Ghochikyan
Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice. Alzheimer's research & therapy 11 (1) (2019)
Rocío Rojo, Anna Raper, Derya D Ozdemir, Lucas Lefevre, Kathleen Grabert, Evi Wollscheid-Lengeling, Barry M Bradford, Melanie Caruso, Iveta Gazova, Alejandra Sánchez, Zofia M Lisowski, Joana Alves, Irene Molina-Gonzalez, Hayk Davtyan, Rebecca J Lodge, James D Glover, Robert Wallace, David A D Munro, Eyal David, Bjørt K Kragesteen, Véronique E Miron, Josef Priller, Stephen J Jenkins, Giles E Hardingham, Mathew Blurton Jones, Neil A Mabbott, Kim M Summers, Peter Hohenstein, David A Hume, Clare Pridans
Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations. Nature communications 10 (1) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Hayk Davtyan