Bart J L Eggen (B J L Eggen)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 37

Top Topics

Gene Expression

Cognitive Impairment

Top Venues

Nature medicine

Seminars in immunopathology

Journal of immunology (Baltimore, Md. : 1950)

This page only lists publications with an associated author ORCID identifier.

Publications

Nienke J Mekkes, Minke Groot, Eric Hoekstra, Alyse de Boer, Ekaterina Dagkesamanskaia, Sander Bouwman, Sophie M T Wehrens, Megan K Herbert, Dennis D Wever, Annemieke J M Rozemuller, Bart J L Eggen, Inge Huitinga, Inge R Holtman
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine 30 (4) (2024)
Neta Rosenzweig, Kilian L Kleemann, Thomas Rust, Madison Carpenter, Madeline Grucci, Michael Aronchik, Nieske Brouwer, Isabel Valenbreder, Joya Cooper-Hohn, Malvika Iyer, Rajesh K Krishnan, Kisha N Sivanathan, Wesley Brandão, Taha Yahya, Ana Durao, Zhuoran Yin, Jean Paul Chadarevian, Michael J Properzi, Roni Nowarski, Hayk Davtyan, Howard L Weiner, Mathew Blurton Jones, Hyun-Sik Yang, Bart J L Eggen, Reisa A Sperling, Oleg Butovsky
Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease. Nature medicine (2024)
Nienke J Mekkes, Minke Groot, Eric Hoekstra, Alyse de Boer, Ekaterina Dagkesamanskaia, Sander Bouwman, Sophie M T Wehrens, Megan K Herbert, Dennis D Wever, Annemieke J M Rozemuller, Bart J L Eggen, Inge Huitinga, Inge R Holtman
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine 30 (4) (2024)
Neta Rosenzweig, Kilian L Kleemann, Thomas Rust, Madison Carpenter, Madeline Grucci, Michael Aronchik, Nieske Brouwer, Isabel Valenbreder, Joya Cooper-Hohn, Malvika Iyer, Rajesh K Krishnan, Kisha N Sivanathan, Wesley Brandão, Taha Yahya, Ana Durao, Zhuoran Yin, Jean Paul Chadarevian, Michael J Properzi, Roni Nowarski, Hayk Davtyan, Howard L Weiner, Mathew Blurton Jones, Hyun-Sik Yang, Bart J L Eggen, Reisa A Sperling, Oleg Butovsky
Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease. Nature medicine (2024)
Nienke J Mekkes, Minke Groot, Eric Hoekstra, Alyse de Boer, Ekaterina Dagkesamanskaia, Sander Bouwman, Sophie M T Wehrens, Megan K Herbert, Dennis D Wever, Annemieke J M Rozemuller, Bart J L Eggen, Inge Huitinga, Inge R Holtman
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine (2024)
Neta Rosenzweig, Kilian L Kleemann, Thomas Rust, Madison Carpenter, Madeline Grucci, Michael Aronchik, Nieske Brouwer, Isabel Valenbreder, Joya Cooper-Hohn, Malvika Iyer, Rajesh K Krishnan, Kisha N Sivanathan, Wesley Brandão, Taha Yahya, Ana Durao, Zhuoran Yin, Jean Paul Chadarevian, Michael J Properzi, Roni Nowarski, Hayk Davtyan, Howard L Weiner, Mathew Blurton Jones, Hyun-Sik Yang, Bart J L Eggen, Reisa A Sperling, Oleg Butovsky
Sex-dependent APOE4 neutrophil-microglia interactions drive cognitive impairment in Alzheimer's disease. Nature medicine (2024)
L J M Mastenbroek, Susanne M Kooistra, Bart J L Eggen, Paola Mian PharmD
The role of microglia in early neurodevelopment and the effects of maternal immune activation. Seminars in immunopathology 46 (1-2) (2024)
Nienke J Mekkes, Minke Groot, Eric Hoekstra, Alyse de Boer, Ekaterina Dagkesamanskaia, Sander Bouwman, Sophie M T Wehrens, Megan K Herbert, Dennis D Wever, Annemieke J M Rozemuller, Bart J L Eggen, Inge Huitinga, Inge R Holtman
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine 30 (4) (2024)
Nienke J Mekkes, Minke Groot, Eric Hoekstra, Alyse de Boer, Ekaterina Dagkesamanskaia, Sander Bouwman, Sophie M T Wehrens, Megan K Herbert, Dennis D Wever, Annemieke J M Rozemuller, Bart J L Eggen, Inge Huitinga, Inge R Holtman
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine 30 (4) (2024)
Takuya Oshima, Mandy S J Kater, Christiaan F M Huffels, Evelyn M Wesseling, Jinte Middeldorp, Elly M Hol, Mark H G Verheijen, August B Smit, Erik W G M Boddeke, Bart J L Eggen
Early amyloid-induced changes in microglia gene expression in male APP/PS1 mice. Journal of neuroscience research 102 (3) (2024)
Nienke J Mekkes, Minke Groot, Eric Hoekstra, Alyse de Boer, Ekaterina Dagkesamanskaia, Sander Bouwman, Sophie M T Wehrens, Megan K Herbert, Dennis D Wever, Annemieke J M Rozemuller, Bart J L Eggen, Inge Huitinga, Inge R Holtman
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine (2024)
Nienke J Mekkes, Minke Groot, Eric Hoekstra, Alyse de Boer, Ekaterina Dagkesamanskaia, Sander Bouwman, Sophie M T Wehrens, Megan K Herbert, Dennis D Wever, Annemieke J M Rozemuller, Bart J L Eggen, Inge Huitinga, Inge R Holtman
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine 30 (4) (2024)
Takuya Oshima, Mandy S J Kater, Christiaan F M Huffels, Evelyn M Wesseling, Jinte Middeldorp, Elly M Hol, Mark H G Verheijen, August B Smit, Erik W G M Boddeke, Bart J L Eggen
Early amyloid-induced changes in microglia gene expression in male APP/PS1 mice. Journal of neuroscience research 102 (3) (2024)
Nienke J Mekkes, Minke Groot, Eric Hoekstra, Alyse de Boer, Ekaterina Dagkesamanskaia, Sander Bouwman, Sophie M T Wehrens, Megan K Herbert, Dennis D Wever, Annemieke J M Rozemuller, Bart J L Eggen, Inge Huitinga, Inge R Holtman
Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine 30 (4) (2024)
L J M Mastenbroek, Susanne M Kooistra, Bart J L Eggen, Paola Mian PharmD
The role of microglia in early neurodevelopment and the effects of maternal immune activation. Seminars in immunopathology 46 (1-2) (2024)
L J M Mastenbroek, Susanne M Kooistra, Bart J L Eggen, Paola Mian PharmD
The role of microglia in early neurodevelopment and the effects of maternal immune activation. Seminars in immunopathology 46 (1-2) (2024)
L J M Mastenbroek, Susanne M Kooistra, Bart J L Eggen, Paola Mian PharmD
The role of microglia in early neurodevelopment and the effects of maternal immune activation. Seminars in immunopathology 46 (1-2) (2024)
Sharon Eskandar, Romy E Bezemer, Bart J L Eggen, Paola Mian PharmD
Cold Mechanical Isolation of Placental Macrophages as a Method to Limit Procedure-Induced Activation of Macrophages. Journal of immunology (Baltimore, Md. : 1950) (2023)
Bart J L Eggen
How the cGAS-STING system links inflammation and cognitive decline. Nature (2023)
Angélica María Sabogal-Guáqueta, Alejandro Marmolejo-Garza, Marina Trombetta-Lima, Asmaa Oun, Jasmijn Hunneman, Tingting Chen, Jari Koistinaho, Sarka Lehtonen, Arjan Kortholt, Justina Clarinda Wolters, Barbara M Bakker, Bart J L Eggen, Erik W G M Boddeke, Amalia Mihaela Dolga
Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction. Nature communications 14 (1) (2023)
Zhuoran Yin, Neta Rosenzweig, Kilian L Kleemann, Xiaoming Zhang, Wesley Brandão, Milica A Margeta, Caitlin Schroeder, Kisha N Sivanathan, Sebastian Silveira, Christian Gauthier, Dania Mallah, Kristen M Pitts, Ana Durao, Shawn Herron, Hannah Shorey, Yiran Cheng, Jen-Li Barry, Rajesh K Krishnan, Sam Wakelin, Jared Rhee, Anthony Yung, Michael Aronchik, Chao Wang, Nimansha Jain, Xin Bao, Emma Gerrits, Nieske Brouwer, Amy Anderson Deik, Daniel Geoffrey Tenen, Tsuneya Ikezu, Nicolás Santander Grez, Gabriel L McKinsey, Caroline Baufeld, Dean Sheppard, Susanne Krasemann, Roni Nowarski, Bart J L Eggen, Andrew T Chan, Rudolph E Tanzi, Charlotte Madore, Thomas D Arnold, David M Holtzman, Oleg Butovsky
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints. Nature immunology (2023)
Hilmar R J van Weering, Tjalling W Nijboer, Maaike L Brummer, Erik W G M Boddeke, Bart J L Eggen
Microglia morphotyping in the adult mouse CNS using hierarchical clustering on principal components reveals regional heterogeneity but no sexual dimorphism. Glia (2023)
Wendy Oost, Allard J Huitema, Kim Kats, Ben N G Giepmans, Susanne M Kooistra, Bart J L Eggen, Wia Baron
Pathological ultrastructural alterations of myelinated axons in normal appearing white matter in progressive multiple sclerosis. Acta neuropathologica communications 11 (1) (2023)
Sofía Puvogel, Astrid Alsema, Laura Kracht, Maree J Webster, Cynthia Shannon Weickert, Iris E C Sommer, Bart J L Eggen
Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes. Molecular psychiatry (2022)
Emma Gerrits, Lucia A A Giannini, Nieske Brouwer, Shamiram Melhem, Danielle Seilhean, Isabelle Le Ber, null null, Alwin Kamermans, Gijs Kooij, Helga E de Vries, Erik W G M Boddeke, Harro Seelaar, John C van Swieten, Bart J L Eggen
Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex. Nature neuroscience 25 (8) (2022)
Ilia D Vainchtein, Astrid M Alsema, Marissa L Dubbelaar, Corien Grit, Jonathan Vinet, Hilmar R J van Weering, Sarah Al-Izki, Giuseppe Biagini, Nieske Brouwer, Sandra Amor, David Baker, Bart J L Eggen, Erik W G M Boddeke, Susanne M Kooistra
Characterizing microglial gene expression in a model of secondary progressive multiple sclerosis. Glia (2022)
Kitty Reemst, Laura Kracht, Janssen M Kotah, Reza Rahimian, Astrid A S van Irsen, Gonzalo Congrains Sotomayor, Laura N Verboon, Nieske Brouwer, Sophie Simard, Gustavo Turecki, Naguib Mechawar, Susanne M Kooistra, Bart J L Eggen, Aniko Korosi
Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions. Translational psychiatry 12 (1) (2022)
Yang Heng, Xiaoming Zhang, Malte Borggrewe, Hilmar R J van Weering, Maaike L Brummer, Tjalling W Nijboer, Leo A B Joosten, Mihai G Netea, Erik W G M Boddeke, Jon D Laman, Bart J L Eggen
Systemic administration of β-glucan induces immune training in microglia. Journal of neuroinflammation 18 (1) (2021)
Thecla A van Wageningen, Emma Gerrits, Sara Palacin I Bonson, Inge Huitinga, Bart J L Eggen, Anne-Marie van Dam
Exploring reported genes of microglia RNA-sequencing data: Uses and considerations. Glia 69 (12) (2021)
Agnieszka Wlodarczyk, Reza Khorooshi, Joanna Marczynska, Inge R Holtman, Mark Burton, Kirstine Nolling Jensen, Morten Blaabjerg, Morten Meyer, Mads Thomassen, Bart J L Eggen, Nasrin Asgari, Trevor Owens
Type I interferon-activated microglia are critical for neuromyelitis optica pathology. Glia 69 (4) (2020)
Laura Kracht, Malte Borggrewe, S Eskandar, N Brouwer, Susana M Chuva de Sousa Lopes, J D Laman, S A Scherjon, Paola Mian PharmD, Susanne M Kooistra, Bart J L Eggen
Human fetal microglia acquire homeostatic immune-sensing properties early in development. Science (New York, N.Y.) 369 (6503) (2020)
Xiaoming Zhang, Yang Heng, Susanne M Kooistra, Hilmar R J van Weering, Maaike L Brummer, Emma Gerrits, Evelyn M Wesseling, Nieske Brouwer, Tjalling W Nijboer, Marissa L Dubbelaar, Erik W G M Boddeke, Bart J L Eggen
Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement. Glia 69 (3) (2020)
Yang Heng, Marissa L Dubbelaar, Suely K N Marie, Erik W G M Boddeke, Bart J L Eggen
The effects of postmortem delay on mouse and human microglia gene expression. Glia 69 (4) (2020)
Malte Borggrewe, Corien Grit, Ilia D Vainchtein, Nieske Brouwer, Evelyn M Wesseling, Jon D Laman, Bart J L Eggen, Susanne M Kooistra, Erik W G M Boddeke
Regionally diverse astrocyte subtypes and their heterogeneous response to EAE. Glia 69 (5) (2020)
Emma Gerrits, Yang Heng, Erik W G M Boddeke, Bart J L Eggen
Transcriptional profiling of microglia; current state of the art and future perspectives. Glia 68 (4) (2019)
Malte Borggrewe, Corien Grit, Wilfred F A Den Dunnen, Saskia M Burm, Jeffrey J Bajramovic, Randolph J Noelle, Bart J L Eggen, Jon D Laman
VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases. Glia 66 (12) (2018)
Yolanda S Kap, Carien Bus-Spoor, Nikki van Driel, Marissa L Dubbelaar, Corien Grit, Susanne M Kooistra, Zahra C Fagrouch, Ernst J Verschoor, Jan Bauer, Bart J L Eggen, Hermie J M Harmsen, Jon D Laman, Bert A 't Hart
Targeted Diet Modification Reduces Multiple Sclerosis-like Disease in Adult Marmoset Monkeys from an Outbred Colony. Journal of immunology (Baltimore, Md. : 1950) 201 (11) (2018)