Helen C Hailes

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 48

Top Topics

Molecular Dynamics Simulations

Tyrosine Kinase

Top Venues

Angewandte Chemie (International ed. in English)

Green chemistry : an international journal and green chemistry resource : GC

This page only lists publications with an associated author ORCID identifier.

Publications

Yu Wang, Yiwen Li, Yeke Ni, Dejan-Krešimir Bučar, Paul A Dalby, John M Ward, Jack W E Jeffries, Helen C Hailes
A transaminase-mediated aldol reaction and applications in cascades to styryl pyridines. Catalysis science & technology 14 (9) (2024)
Fangyuan Zhang, Amy I Jacobs, Maximillian Woodall, Helen C Hailes, Ijeoma F Uchegbu, Delmiro Fernandez-Reyes, Claire Mary Smith, Karolina Dziemidowicz, Gareth R William
A one-step method for generating antimicrobial nanofibre meshes via coaxial electrospinning. Materials advances 5 (13) (2024)
Jorge González-Rodríguez, Sergio González-Granda, Hirdesh Kumar, Oscar Alvizo, Lorena Escot, Helen C Hailes, Vicente Gotor-Fernández, Iván Lavandera
BioLindlar Catalyst: Ene-Reductase-Promoted Selective Bioreduction of Cyanoalkynes to Give (Z)-Cyanoalkenes. Angewandte Chemie (International ed. in English) (2024)
Luba Prout, Helen C Hailes, John M Ward
Natural transaminase fusions for biocatalysis. RSC advances 14 (6) (2024)
Yu Wang, Yiwen Li, Yeke Ni, Dejan-Krešimir Bučar, Paul A Dalby, John M Ward, Jack W E Jeffries, Helen C Hailes
A transaminase-mediated aldol reaction and applications in cascades to styryl pyridines. Catalysis science & technology 14 (9) (2024)
Fangyuan Zhang, Amy I Jacobs, Maximillian Woodall, Helen C Hailes, Ijeoma F Uchegbu, Delmiro Fernandez-Reyes, Claire Mary Smith, Karolina Dziemidowicz, Gareth R William
A one-step method for generating antimicrobial nanofibre meshes via coaxial electrospinning. Materials advances 5 (13) (2024)
Luba Prout, Helen C Hailes, John M Ward
Natural transaminase fusions for biocatalysis. RSC advances 14 (6) (2024)
Douglas Weber, Lucas de Souza Bastos, Margit Winkler, Yeke Ni, Abil E Aliev, Helen C Hailes, Doerte Rother
Multi-enzyme catalysed processes using purified and whole-cell biocatalysts towards a 1,3,4-substituted tetrahydroisoquinoline. RSC advances 13 (15) (2023)
Max Cárdenas-Fernández, Rebecca Roddan, Eve M Carter, Helen C Hailes, John M Ward
The Discovery of Imine Reductases and their Utilisation for the Synthesis of Tetrahydroisoquinolines. ChemCatChem 15 (3) (2023)
Esther Ambrose-Dempster, Leona Leipold, Dragana Dobrijevic, Maria Bawn, Eve M Carter, Gorjan Stojanovski, Tom D Sheppard, Jack W E Jeffries, John M Ward, Helen C Hailes
Mechanoenzymatic reactions for the hydrolysis of PET. RSC advances 13 (15) (2023)
Max Cárdenas-Fernández, Rebecca Roddan, Eve M Carter, Helen C Hailes, John M Ward
The Discovery of Imine Reductases and their Utilisation for the Synthesis of Tetrahydroisoquinolines. ChemCatChem 15 (3) (2023)
Max Cárdenas-Fernández, Rebecca Roddan, Eve M Carter, Helen C Hailes, John M Ward
The Discovery of Imine Reductases and their Utilisation for the Synthesis of Tetrahydroisoquinolines. ChemCatChem 15 (3) (2023)
Lili Cui, Laila Kudsiova, Frederick Campbell, David J Barlow, Helen C Hailes, Alethea B Tabor, M Jayne Lawrence
Understanding and optimising the transfection of lipopolyplexes formulated in saline: the effects of peptide and serum. Biomaterials science (2023)
Max Cárdenas-Fernández, Rebecca Roddan, Eve M Carter, Helen C Hailes, John M Ward
The Discovery of Imine Reductases and their Utilisation for the Synthesis of Tetrahydroisoquinolines. ChemCatChem 15 (3) (2023)
Yeke Ni, Yu Wang, Alethea B Tabor, John M Ward, Helen C Hailes
The use of tyrosinases in a chemoenzymatic cascade as a peptide ligation strategy. RSC chemical biology 4 (2) (2022)
Omri Tau, Alice Henley, Anton N Boichenko, Nadezhda N Kleshchina, River Riley, Bingxing Wang, Danielle Winning, Ross Lewin, Ivan P Parkin, John M Ward, Helen C Hailes, Anastasia V Bochenkova, Helen H Fielding
Liquid-microjet photoelectron spectroscopy of the green fluorescent protein chromophore. Nature communications 13 (1) (2022)
Gorjan Stojanovski, Helen C Hailes, John M Ward
Facile and selective N -alkylation of gentamicin antibiotics via chemoenzymatic synthesis. Green chemistry : an international journal and green chemistry resource : GC 24 (24) (2022)
Rebecca Roddan, Eve M Carter, Benjamin Thair, Helen C Hailes
Chemoenzymatic approaches to plant natural product inspired compounds. Natural product reports 39 (7) (2022)
Gorjan Stojanovski, Helen C Hailes, John M Ward
Facile and selective N -alkylation of gentamicin antibiotics via chemoenzymatic synthesis. Green chemistry : an international journal and green chemistry resource : GC 24 (24) (2022)
Yu Wang, Fabiana Subrizi, Eve M Carter, Tom D Sheppard, John M Ward, Helen C Hailes
Enzymatic synthesis of benzylisoquinoline alkaloids using a parallel cascade strategy and tyrosinase variants. Nature communications 13 (1) (2022)
Eman M M Abdelraheem, Benjamin Thair, Romina Fernández Varela, Emely Jockmann, Désirée Popadić, Helen C Hailes, John M Ward, Adolfo M Iribarren, Elizabeth S Lewkowicz, Jennifer N Andexer, Peter Leon Hagedoorn, Ulf Hanefeld
Methyltransferases: Functions and Applications. Chembiochem : a European journal of chemical biology 23 (18) (2022)
Max Cárdenas-Fernández, Fabiana Subrizi, Dragana Dobrijevic, Helen C Hailes, John M Ward
Characterisation of a hyperthermophilic transketolase from Thermotoga maritima DSM3109 as a biocatalyst for 7-keto-octuronic acid synthesis. Organic & biomolecular chemistry 19 (29) (2022)
Yeke Ni, Yu Wang, Alethea B Tabor, John M Ward, Helen C Hailes
The use of tyrosinases in a chemoenzymatic cascade as a peptide ligation strategy. RSC chemical biology 4 (2) (2022)
Joanne L Woodhouse, Alice Henley, Ross Lewin, John M Ward, Helen C Hailes, Anastasia V Bochenkova, Helen H Fielding
A photoelectron imaging study of the deprotonated GFP chromophore anion and RNA fluorescent tags. Physical chemistry chemical physics : PCCP 23 (35) (2021)
Robin Bofinger, Gregory Weitsman, Rachel Evans, Matthias Glaser, Kerstin Sander, Helen Allan, Daniel Hochhauser, Tammy L Kalber, Erik Årstad, Helen C Hailes, Tony T Ng, Alethea B Tabor
Drug delivery, biodistribution and anti-EGFR activity: theragnostic nanoparticles for simultaneous in vivo delivery of tyrosine kinase inhibitors and kinase activity biosensors. Nanoscale 13 (44) (2021)
Sophie A Newgas, Jack W E Jeffries, Thomas S Moody, John M Ward, Helen C Hailes
Discovery of New Carbonyl Reductases Using Functional Metagenomics and Applications in Biocatalysis. Advanced synthesis & catalysis 363 (12) (2021)
Désirée Popadić, Dipali Mhaindarkar, Mike H N Dang Thai, Helen C Hailes, Silja Mordhorst, Jennifer N Andexer
A bicyclic S-adenosylmethionine regeneration system applicable with different nucleosides or nucleotides as cofactor building blocks. RSC chemical biology 2 (3) (2021)
Fabiana Subrizi, Yu Wang, Benjamin Thair, Daniel Méndez-Sánchez, Rebecca Roddan, Max Cárdenas-Fernández, Jutta Siegrist, Michael Richter, Jennifer N Andexer, John M Ward, Helen C Hailes
Multienzyme One-Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 133 (34) (2021)
Eve M Carter, Fabiana Subrizi, John M Ward, Tom D Sheppard, Helen C Hailes
Direct Conversion of Hydrazones to Amines using Transaminases. ChemCatChem 13 (21) (2021)
Rachel Szpara, Alexander Goyder, Michael J Porter, Helen C Hailes, Tom D Sheppard
Regioselective Dehydration of Sugar Thioacetals under Mild Conditions. Organic letters 23 (7) (2021)
Fabiana Subrizi, Yu Wang, Benjamin Thair, Daniel Méndez-Sánchez, Rebecca Roddan, Max Cárdenas-Fernández, Jutta Siegrist, Michael Richter, Jennifer N Andexer, John M Ward, Helen C Hailes
Multienzyme One-Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids. Angewandte Chemie (International ed. in English) 60 (34) (2021)
Fabiana Subrizi, Yu Wang, Benjamin Thair, Daniel Méndez-Sánchez, Rebecca Roddan, Max Cárdenas-Fernández, Jutta Siegrist, Michael Richter, Jennifer N Andexer, John M Ward, Helen C Hailes
Multienzyme One-Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 133 (34) (2021)
Rebecca Roddan, Fabiana Subrizi, Joseph Broomfield, John M Ward, Nicholas H Keep, Helen C Hailes
Chemoenzymatic Cascades toward Methylated Tetrahydroprotoberberine and Protoberberine Alkaloids. Organic letters 23 (16) (2021)
May Zaw Thin, Helen Allan, Robin Bofinger, Tomas D Kostelec, Simon Guillaume, John J Connell, Peter Stephen Patrick, Helen C Hailes, Alethea B Tabor, Mark F Lythgoe, Daniel J Stuckey, Tammy L Kalber
Multi-modal imaging probe for assessing the efficiency of stem cell delivery to orthotopic breast tumours. Nanoscale 12 (31) (2020)
Dragana Dobrijevic, Lily A Nematollahi, Helen C Hailes, John M Ward
pET expression vector customized for efficient seamless cloning. BioTechniques 69 (5) (2020)
Rebecca Roddan, Altin Sula, Daniel Méndez-Sánchez, Fabiana Subrizi, Benjamin R Lichman, Joseph Broomfield, Michael Richter, Jennifer N Andexer, John M Ward, Nicholas H Keep, Helen C Hailes
Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases. Communications chemistry 3 (1) (2020)
Rebecca Roddan, Altin Sula, Daniel Méndez-Sánchez, Fabiana Subrizi, Benjamin R Lichman, Joseph Broomfield, Michael Richter, Jennifer N Andexer, John M Ward, Nicholas H Keep, Helen C Hailes
Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases. Communications chemistry 3 (1) (2020)
Dragana Dobrijevic, Laure Benhamou, Abil E Aliev, Daniel Méndez-Sánchez, Natalie Dawson, Damien Baud, Nadine Tappertzhofen, Thomas S Moody, Christine A Orengo, Helen C Hailes, John M Ward
Metagenomic ene-reductases for the bioreduction of sterically challenging enones. RSC advances 9 (63) (2019)
Jianxiong Zhao, Daniel Méndez-Sánchez, John M Ward, Helen C Hailes
Biomimetic Phosphate-Catalyzed Pictet-Spengler Reaction for the Synthesis of 1,1'-Disubstituted and Spiro-Tetrahydroisoquinoline Alkaloids. The Journal of organic chemistry 84 (12) (2019)
Yu Wang, Nadine Tappertzhofen, Daniel Méndez-Sánchez, Maria Bawn, Boyu Lyu, John M Ward, Helen C Hailes
Design and Use of de novo Cascades for the Biosynthesis of New Benzylisoquinoline Alkaloids. Angewandte Chemie (International ed. in English) 58 (30) (2019)
Laila Kudsiova, Atefeh Mohammadi, M Firouz Mohd Mustapa, Frederick Campbell, Katharina Welser, Danielle Vlaho, Harriet Story, David J Barlow, Alethea B Tabor, Helen C Hailes, M Jayne Lawrence
Trichain cationic lipids: the potential of their lipoplexes for gene delivery. Biomaterials science 7 (1) (2019)
Eleni Demetriou, Harriet E Story, Robin Bofinger, Helen C Hailes, Alethea B Tabor, Xavier Golay
Effect of Liposomal Encapsulation on the Chemical Exchange Properties of Diamagnetic CEST Agents. The journal of physical chemistry. B 123 (35) (2019)
Charlotte E Coomber, Victor Laserna, Liam T Martin, Peter D Smith, Helen C Hailes, Michael J Porter, Tom D Sheppard
Catalytic direct amidations in tert-butyl acetate using B(OCH2CF3)3. Organic & biomolecular chemistry 17 (26) (2019)
Fabiana Subrizi, Laure Benhamou, John M Ward, Tom D Sheppard, Helen C Hailes
Aminopolyols from Carbohydrates: Amination of Sugars and Sugar-Derived Tetrahydrofurans with Transaminases. Angewandte Chemie (International ed. in English) 58 (12) (2019)
Valerija Karaluka, Kengo Murata, Shinto Masuda, Yuto Shiramatsu, Takuji Kawamoto, Helen C Hailes, Tom D Sheppard, Akio Kamimura
Development of a microwave-assisted sustainable conversion of furfural hydrazones to functionalised phthalimides in ionic liquids. RSC advances 8 (40) (2018)
Leona Leipold, Dragana Dobrijevic, Jack W E Jeffries, Maria Bawn, Thomas S Moody, John M Ward, Helen C Hailes
The identification and use of robust transaminases from a domestic drain metagenome. Green chemistry : an international journal and green chemistry resource : GC 21 (1) (2018)
Anastasia V Bochenkova, Ciarán R S Mooney, Michael A Parkes, Joanne L Woodhouse, Lijuan Zhang, Ross Lewin, John M Ward, Helen C Hailes, Lars H Andersen, Helen H Fielding
Mechanism of resonant electron emission from the deprotonated GFP chromophore and its biomimetics. Chemical science 8 (4) (2017)
Conor McLaughlin, Mariana Assmann, Michael A Parkes, Joanne L Woodhouse, Ross Lewin, Helen C Hailes, Graham A Worth, Helen H Fielding
ortho and para chromophores of green fluorescent protein: controlling electron emission and internal conversion. Chemical science 8 (2) (2016)