Paul A Dalby (P Dalby)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 40

Top Topics

Machine Learning

Gas Chromatography

Top Venues

Molecular pharmaceutics

Journal of chemical information and modeling

ACS applied bio materials

This page only lists publications with an associated author ORCID identifier.

Publications

Niccolo Alberto Elia Venanzi, Andrea Basciu, Attilio Vittorio Vargiu, Alexandros Kiparissides, Paul A Dalby, Duygu Dikicioglu
Machine Learning Integrating Protein Structure, Sequence, and Dynamics to Predict the Enzyme Activity of Bovine Enterokinase Variants. Journal of chemical information and modeling 64 (7) (2024)
Alexander Van de Steen, Henry C Wilkinson, Paul A Dalby, Stefanie Frank
Encapsulation of Transketolase into In Vitro -Assembled Protein Nanocompartments Improves Thermal Stability. ACS applied bio materials 7 (6) (2024)
Alexander Van de Steen, Henry C Wilkinson, Paul A Dalby, Stefanie Frank
Encapsulation of Transketolase into In Vitro -Assembled Protein Nanocompartments Improves Thermal Stability. ACS applied bio materials (2024)
Victoria E Wood, Mark-Adam Kellerman, Kate Groves, Milena Quaglia, Elizabeth M Topp, Paul Matejtschuk, Paul A Dalby
Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen-Deuterium Exchange Mass Spectrometry. Molecular pharmaceutics 21 (4) (2024)
Alexander Van de Steen, Henry C Wilkinson, Paul A Dalby, Stefanie Frank
Encapsulation of Transketolase into In Vitro -Assembled Protein Nanocompartments Improves Thermal Stability. ACS applied bio materials 7 (6) (2024)
Valentina A Spiteri, James Doutch, Robert P Rambo, Jayesh S Bhatt, Jayesh Gor, Paul A Dalby, Stephen J Perkins
Using atomistic solution scattering modelling to elucidate the role of the Fc glycans in human IgG4. PloS one 19 (4) (2024)
Niccolo Alberto Elia Venanzi, Andrea Basciu, Attilio Vittorio Vargiu, Alexandros Kiparissides, Paul A Dalby, Duygu Dikicioglu
Machine Learning Integrating Protein Structure, Sequence, and Dynamics to Predict the Enzyme Activity of Bovine Enterokinase Variants. Journal of chemical information and modeling 64 (7) (2024)
Victoria E Wood, Mark-Adam Kellerman, Kate Groves, Milena Quaglia, Elizabeth M Topp, Paul Matejtschuk, Paul A Dalby
Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen-Deuterium Exchange Mass Spectrometry. Molecular pharmaceutics 21 (4) (2024)
Victoria E Wood, Mark-Adam Kellerman, Kate Groves, Milena Quaglia, Elizabeth M Topp, Paul Matejtschuk, Paul A Dalby
Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen-Deuterium Exchange Mass Spectrometry. Molecular pharmaceutics 21 (4) (2024)
Niccolo Alberto Elia Venanzi, Andrea Basciu, Attilio Vittorio Vargiu, Alexandros Kiparissides, Paul A Dalby, Duygu Dikicioglu
Machine Learning Integrating Protein Structure, Sequence, and Dynamics to Predict the Enzyme Activity of Bovine Enterokinase Variants. Journal of chemical information and modeling 64 (7) (2024)
Victoria E Wood, Mark-Adam Kellerman, Kate Groves, Milena Quaglia, Elizabeth M Topp, Paul Matejtschuk, Paul A Dalby
Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen-Deuterium Exchange Mass Spectrometry. Molecular pharmaceutics 21 (4) (2024)
Yu Wang, Yiwen Li, Yeke Ni, Dejan-Krešimir Bučar, Paul A Dalby, John M Ward, Jack W E Jeffries, Helen C Hailes
A transaminase-mediated aldol reaction and applications in cascades to styryl pyridines. Catalysis science & technology 14 (9) (2024)
Victoria E Wood, Mark-Adam Kellerman, Kate Groves, Milena Quaglia, Elizabeth M Topp, Paul Matejtschuk, Paul A Dalby
Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen-Deuterium Exchange Mass Spectrometry. Molecular pharmaceutics 21 (4) (2024)
Niccolo Alberto Elia Venanzi, Andrea Basciu, Attilio Vittorio Vargiu, Alexandros Kiparissides, Paul A Dalby, Duygu Dikicioglu
Machine Learning Integrating Protein Structure, Sequence, and Dynamics to Predict the Enzyme Activity of Bovine Enterokinase Variants. Journal of chemical information and modeling 64 (7) (2024)
Victoria E Wood, Mark-Adam Kellerman, Kate Groves, Milena Quaglia, Elizabeth M Topp, Paul Matejtschuk, Paul A Dalby
Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen-Deuterium Exchange Mass Spectrometry. Molecular pharmaceutics (2024)
Niccolo Alberto Elia Venanzi, Andrea Basciu, Attilio Vittorio Vargiu, Alexandros Kiparissides, Paul A Dalby, Duygu Dikicioglu
Machine Learning Integrating Protein Structure, Sequence, and Dynamics to Predict the Enzyme Activity of Bovine Enterokinase Variants. Journal of chemical information and modeling (2024)
Niccolo Alberto Elia Venanzi, Andrea Basciu, Attilio Vittorio Vargiu, Alexandros Kiparissides, Paul A Dalby, Duygu Dikicioglu
Machine Learning Integrating Protein Structure, Sequence, and Dynamics to Predict the Enzyme Activity of Bovine Enterokinase Variants. Journal of chemical information and modeling 64 (7) (2024)
Yu Wang, Yiwen Li, Yeke Ni, Dejan-Krešimir Bučar, Paul A Dalby, John M Ward, Jack W E Jeffries, Helen C Hailes
A transaminase-mediated aldol reaction and applications in cascades to styryl pyridines. Catalysis science & technology 14 (9) (2024)
Alexander Van de Steen, Henry C Wilkinson, Paul A Dalby, Stefanie Frank
Encapsulation of Transketolase into In Vitro -Assembled Protein Nanocompartments Improves Thermal Stability. ACS applied bio materials 7 (6) (2024)
Niccolo Alberto Elia Venanzi, Andrea Basciu, Attilio Vittorio Vargiu, Alexandros Kiparissides, Paul A Dalby, Duygu Dikicioglu
Machine Learning Integrating Protein Structure, Sequence, and Dynamics to Predict the Enzyme Activity of Bovine Enterokinase Variants. Journal of chemical information and modeling 64 (7) (2024)
Valentina A Spiteri, James Doutch, Robert P Rambo, Jayesh S Bhatt, Jayesh Gor, Paul A Dalby, Stephen J Perkins
Using atomistic solution scattering modelling to elucidate the role of the Fc glycans in human IgG4. PloS one 19 (4) (2024)
Cheng Zhang, Jordan W Bye, Lok H Lui, Hongyu Zhang, John E Hales, Steve Brocchini, Robin A Curtis, Paul A Dalby
Enhanced Thermal Stability and Reduced Aggregation in an Antibody Fab Fragment at Elevated Concentrations. Molecular pharmaceutics (2023)
Cheng Zhang, Adam Berg, Carina C D Joe, Paul A Dalby, Alexander D Douglas
Lyophilization to enable distribution of ChAdOx1 and ChAdOx2 adenovirus-vectored vaccines without refrigeration. NPJ vaccines 8 (1) (2023)
Wenfeng Shen, Paul A Dalby, Zheng Guo, Wei-Na Li, Chenhui Zhu, Daidi Fan
Residue Effect-Guided Design: Engineering of S. Solfataricus β-Glycosidase to Enhance Its Thermostability and Bioproduction of Ginsenoside Compound K. Journal of agricultural and food chemistry (2023)
Mark-Adam W Kellerman, Teresa Almeida, Timothy R Rudd, Paul Matejtschuk, Paul A Dalby
NMR Reveals Functionally Relevant Thermally Induced Structural Changes within the Native Ensemble of G-CSF. Molecular pharmaceutics 19 (9) (2022)
Yiwen Li, Paul A Dalby
Engineering of enzymes using non-natural amino acids. Bioscience reports 42 (8) (2022)
Hongyu Zhang, Paul A Dalby
Stability Convergence in Antibody Coformulations. Molecular pharmaceutics 19 (11) (2022)
Victoria E Wood, Kate Groves, Lok Man Wong, Luyan Kong, Christopher Bird, Meenu Wadhwa, Milena Quaglia, Paul Matejtschuk, Paul A Dalby
Protein Engineering and HDX Identify Structural Regions of G-CSF Critical to Its Stability and Aggregation. Molecular pharmaceutics 19 (2) (2021)
Kate Groves, Alison E Ashcroft, A Cryar, A Sula, B A Wallace, Bradley B Stocks, C Burns, D Cooper-Shepherd, Ersilia De Lorenzi, E Rodriguez, H Zhang, J R Ault, J Ferguson, Jonathan J Phillips, K Pacholarz, Konstantinos Thalassinos, L Luckau, Lorna Ashton, O Durrant, Perdita E Barran, Paul A Dalby, P Vicedo, R Colombo, R Davis, R Parakra, R Upton, Sarah Hill, V Wood, Z Soloviev, M Quaglia
Reference Protocol to Assess Analytical Performance of Higher Order Structural Analysis Measurements: Results from an Interlaboratory Comparison. Analytical chemistry 93 (26) (2021)
Henry C Wilkinson, Paul A Dalby
The Two-Species Model of transketolase explains donor substrate-binding, inhibition and heat-activation. Scientific reports 10 (1) (2020)
Victoria E Wood, Kate Groves, Adam Cryar, Milena Quaglia, Paul Matejtschuk, Paul A Dalby
HDX and In Silico Docking Reveal that Excipients Stabilize G-CSF via a Combination of Preferential Exclusion and Specific Hotspot Interactions. Molecular pharmaceutics 17 (12) (2020)
Henry C Wilkinson, Paul A Dalby
Fine-tuning the activity and stability of an evolved enzyme active-site through noncanonical amino-acids. The FEBS journal 288 (6) (2020)
John E Hales, Guy Matmon, Paul A Dalby, John M Ward, Gabriel Aeppli
Virus lasers for biological detection. Nature communications 10 (1) (2019)
Mathew J Robinson, Paul Matejtschuk, Colin Longstaff, Paul A Dalby
Selective Stabilization and Destabilization of Protein Domains in Tissue-Type Plasminogen Activator Using Formulation Excipients. Molecular pharmaceutics 16 (2) (2019)
Henry C Wilkinson, Paul A Dalby
Novel insights into transketolase activation by cofactor binding identifies two native species subpopulations. Scientific reports 9 (1) (2019)
Cheng Zhang, Maariyah Samad, Haoran Yu, Nesrine Chakroun, David Hilton, Paul A Dalby
Computational Design To Reduce Conformational Flexibility and Aggregation Rates of an Antibody Fab Fragment. Molecular pharmaceutics 15 (8) (2018)
Haoran Yu, Paul A Dalby
Coupled molecular dynamics mediate long- and short-range epistasis between mutations that affect stability and aggregation kinetics. Proceedings of the National Academy of Sciences of the United States of America 115 (47) (2018)
Haoran Yu, Paul A Dalby
Exploiting correlated molecular-dynamics networks to counteract enzyme activity-stability trade-off. Proceedings of the National Academy of Sciences of the United States of America 115 (52) (2018)
Akash Pandya, Mark J Howard, Mire Zloh, Paul A Dalby
An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations. Pharmaceutics 10 (4) (2018)
Mathew J Robinson, Paul Matejtschuk, Adrian F Bristow, Paul A Dalby
Tm-Values and Unfolded Fraction Can Predict Aggregation Rates for Granulocyte Colony Stimulating Factor Variant Formulations but Not under Predominantly Native Conditions. Molecular pharmaceutics 15 (1) (2017)