Hong C Shen

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 16

Top Venues

Journal of medicinal chemistry

The Journal of organic chemistry

ACS infectious diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Weixing Zhang, Lei Guo, Haixia Liu, Guolong Wu, Houguang Shi, Mingwei Zhou, Zhisen Zhang, Buyu Kou, Taishan Hu, Zheng Zhou, Zhiheng Xu, Xue Zhou, Yuan Zhou, Xiaojun Tian, Guang Yang, John A T Young, Hongxia Qiu, Giorgio Ottaviani, Jianxun Xie, Alexander V Mayweg, Hong C Shen, Wei Zhu
Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection. Journal of medicinal chemistry 66 (6) (2023)
Weixing Zhang, Lei Guo, Haixia Liu, Guolong Wu, Houguang Shi, Mingwei Zhou, Zhisen Zhang, Buyu Kou, Taishan Hu, Zheng Zhou, Zhiheng Xu, Xue Zhou, Yuan Zhou, Xiaojun Tian, Guang Yang, John A T Young, Hongxia Qiu, Giorgio Ottaviani, Jianxun Xie, Alexander V Mayweg, Hong C Shen, Wei Zhu
Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection. Journal of medicinal chemistry 66 (6) (2023)
Buyu Kou, Zhisen Zhang, Xingchun Han, Zheng Zhou, Zhiheng Xu, Xue Zhou, Fang Shen, Yuan Zhou, Xiaojun Tian, Guang Yang, John A T Young, Hongxia Qiu, Giorgio Ottaviani, Alexander Mayweg, Wei Zhu, Hong C Shen, Haixia Liu, Taishan Hu
Discovery of 4,5,6,7-Tetrahydropyrazolo[1.5-a]pyrizine Derivatives as Core Protein Allosteric Modulators (CpAMs) for the Inhibition of Hepatitis B Virus. Journal of medicinal chemistry (2023)
Weixing Zhang, Lei Guo, Haixia Liu, Guolong Wu, Houguang Shi, Mingwei Zhou, Zhisen Zhang, Buyu Kou, Taishan Hu, Zheng Zhou, Zhiheng Xu, Xue Zhou, Yuan Zhou, Xiaojun Tian, Guang Yang, John A T Young, Hongxia Qiu, Giorgio Ottaviani, Jianxun Xie, Alexander V Mayweg, Hong C Shen, Wei Zhu
Discovery of Linvencorvir (RG7907), a Hepatitis B Virus Core Protein Allosteric Modulator, for the Treatment of Chronic HBV Infection. Journal of medicinal chemistry (2023)
Dongdong Chen, Xuefei Tan, Wenming Chen, Yongfu Liu, Chao Li, Jun Wu, Jiamin Zheng, Hong C Shen, Meifang Zhang, Waikwong Wu, Lin Wang, Jing Xiong, Jieyu Dai, Kai Sun, Jitao David Zhang, Kunlun Xiang, Baocun Li, XiaoJu Ni, Qihui Zhu, Lu Gao, Li Wang, Song Feng
Discovery of Novel cccDNA Reducers toward the Cure of Hepatitis B Virus Infection. Journal of medicinal chemistry 65 (16) (2022)
Yongfu Liu, Jun Wu, Mingwei Zhou, Wenming Chen, Dongbo Li, Zhanguo Wang, Benoit Hornsperger, Johannes D Aebi, Hans-Peter Märki, Bernd Kuhn, Lisha Wang, Andreas Kuglstatter, Jörg Benz, Stephan Müller, Remo Hochstrasser, Giorgio Ottaviani, Jian Xin, Stephan Kirchner, Susanne Mohr, Philippe Verry, William Riboulet, Hong C Shen, Alexander V Mayweg, Kurt Amrein, Xuefei Tan
Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors. Journal of medicinal chemistry 63 (13) (2020)
Yimin Hu, Houguang Shi, Mingwei Zhou, Qingcheng Ren, Wei Zhu, Weixing Zhang, Zhiwei Zhang, Chengang Zhou, Yongqiang Liu, Xiao Ding, Hong C Shen, S Frank Yan, Fabian Dey, Waikwong Wu, Guanglei Zhai, Zheng Zhou, Zhiheng Xu, Ying Ji, Hua Lv, Tianyi Jiang, Wen Wang, Yunhua Xu, Maarten Vercruysse, Xiangyu Yao, Yi Mao, Xiaomin Yu, Kenneth Bradley, Xuefei Tan
Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV. Journal of medicinal chemistry 63 (17) (2020)
Xiufang Zheng, Lu Gao, Lisha Wang, Chungen Liang, Baoxia Wang, Yongfu Liu, Song Feng, Bo Zhang, Mingwei Zhou, Xin Yu, Kunlun Xiang, Li Chen, Tao Guo, Hong C Shen, Gang Zou, Jim Zhen Wu, Hongying Yun
Discovery of Ziresovir as a Potent, Selective, and Orally Bioavailable Respiratory Syncytial Virus Fusion Protein Inhibitor. Journal of medicinal chemistry 62 (13) (2019)
Xianfeng Lin, Houguang Shi, Weixing Zhang, Zongxing Qiu, Zheng Zhou, Fabian Dey, Sheng Zhong, Hongxia Qiu, Jianxun Xie, Xue Zhou, Guang Yang, Guozhi Tang, Hong C Shen, Wei Zhu
A New Approach of Mitigating CYP3A4 Induction Led to the Discovery of Potent Hepatitis B Virus (HBV) Capsid Inhibitor with Optimal ADMET Profiles. Journal of medicinal chemistry 62 (22) (2019)
Xingchun Han, Chengang Zhou, Min Jiang, Yongguang Wang, Jianhua Wang, Zhanling Cheng, Min Wang, Yongqiang Liu, Chungen Liang, Jianping Wang, Zhanguo Wang, Robert Weikert, Wenzhe Lv, Jianxun Xie, Xin Yu, Xue Zhou, Souphalone Luangsay, Hong C Shen, Alexander V Mayweg, Hassan Javanbakht, Song Yang
Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action. Journal of medicinal chemistry 61 (23) (2018)
Jun Wu, Hui Zhang, Xiao Ding, Xuefei Tan, Jie Chen, Weimin He, Hongmei Deng, Liping Song, Hong C Shen, Weiguo Cao
Potassium Iodide-Promoted One-Pot Synthesis of Fluoroalkylated Quinoxalines via a Tandem Michael Addition/Azidation/Cycloamination Approach. The Journal of organic chemistry 83 (16) (2018)
Song Feng, Lu Gao, Xingchun Han, Taishan Hu, Yimin Hu, Haixia Liu, Andrew W Thomas, Zhipeng Yan, Song Yang, John A T Young, Hongying Yun, Wei Zhu, Hong C Shen
Discovery of Small Molecule Therapeutics for Treatment of Chronic HBV Infection. ACS infectious diseases 4 (3) (2018)
Changhui Lu, Hao Lu, Jiang Wu, Hong C Shen, Taishan Hu, Yucheng Gu, Qilong Shen
Palladium-Catalyzed Difluoromethylation of Aryl Chlorides and Triflates and Its Applications in the Preparation of Difluoromethylated Derivatives of Drug/Agrochemical Molecules. The Journal of organic chemistry 83 (2) (2018)
Xiufang Zheng, Chungen Liang, Lisha Wang, Baoxia Wang, Yongfu Liu, Song Feng, Jim Zhen Wu, Lu Gao, Lichun Feng, Li Chen, Tao Guo, Hong C Shen, Hongying Yun
Discovery of Benzoazepinequinoline (BAQ) Derivatives as Novel, Potent, Orally Bioavailable Respiratory Syncytial Virus Fusion Inhibitors. Journal of medicinal chemistry 61 (22) (2018)
Mingwei Zhou, Xuefei Tan, Yimin Hu, Hong C Shen, Xuhong Qian
Highly Chemo- and Regioselective Vinylation of N-Heteroarenes with Vinylsulfonium Salts. The Journal of organic chemistry 83 (15) (2018)
Zhanling Cheng, Zhiliang Yu, Song Yang, Hong C Shen, Weili Zhao, Sheng Zhong
C-H Bond Functionalization of Tetrahydropyridopyrimidines and Other Related Hetereocycles. The Journal of organic chemistry 82 (24) (2017)

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Publication Activity (10 Years)

Top Topics

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Hong C Shen