Jake A Melby

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 36

Top Topics

Mass Spectrometry

Skeletal Muscle

Ultra High Performance Liquid Chromatography

Top Venues

bioRxiv : the preprint server for biology

Journal of proteome research

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Holden T Rogers, Jake A Melby, Lauren E Ehlers, Matthew S Fischer, Eli J Larson, Zhan Gao, Kalina J Rossler, Daojing Wang, Andrew J Alpert, Ying Ge
Small-Scale Serial Size Exclusion Chromatography (s 3 SEC) for High Sensitivity Top-Down Proteomics of Large Proteoforms. Analytical chemistry (2024)
Holden T Rogers, Jake A Melby, Lauren E Ehlers, Matthew S Fischer, Eli J Larson, Zhan Gao, Kalina J Rossler, Daojing Wang, Andrew J Alpert, Ying Ge
Small-Scale Serial Size Exclusion Chromatography (s 3 SEC) for High Sensitivity Top-Down Proteomics of Large Proteoforms. Analytical chemistry (2024)
Holden T Rogers, Jake A Melby, Lauren E Ehlers, Matthew S Fischer, Eli J Larson, Zhan Gao, Kalina J Rossler, Daojing Wang, Andrew J Alpert, Ying Ge
Small-Scale Serial Size Exclusion Chromatography (s 3 SEC) for High Sensitivity Top-Down Proteomics of Large Proteoforms. Analytical chemistry (2024)
Eli J Larson, Melissa R Pergande, Michelle E Moss, Kalina J Rossler, R Kent Wenger, Boris Krichel, Harini Josyer, Jake A Melby, David S Roberts, Kyndalanne Pike, Zhuoxin Shi, Hsin-Ju Chan, Bridget Knight, Holden T Rogers, Kyle A Brown, Irene M Ong, Kyowon Jeong, Michael Thomas Marty, Sean J McIlwain, Ying Ge
MASH Native: A Unified Solution for Native Top-Down Proteomics Data Processing. bioRxiv : the preprint server for biology (2023)
Holden T Rogers, David S Roberts, Eli J Larson, Jake A Melby, Kalina J Rossler, Austin V Carr, Kyle A Brown, Ying Ge
Comprehensive Characterization of Endogenous Phospholamban Proteoforms Enabled by Photocleavable Surfactant and Top-down Proteomics. bioRxiv : the preprint server for biology (2023)
Jake A Melby, Kyle A Brown, Zachery R Gregorich, David S Roberts, Emily A Chapman, Lauren E Ehlers, Zhan Gao, Eli J Larson, Yutong Jin, Justin R Lopez, Jared Hartung, Yanlong Zhu, Sean J McIlwain, Daojing Wang, Wei Guo, Gary M Diffee, Ying Ge
High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Emily A Chapman, David S Roberts, Timothy N Tiambeng, Jaan Andrews, Man-Di Wang, Emily A Reasoner, Jake A Melby, Brad H Li, Donguk Kim, Andrew J Alpert, Song Jin, Ying Ge
Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics. Nature communications 14 (1) (2023)
Jake A Melby, Kyle A Brown, Zachery R Gregorich, David S Roberts, Emily A Chapman, Lauren E Ehlers, Zhan Gao, Eli J Larson, Yutong Jin, Justin R Lopez, Jared Hartung, Yanlong Zhu, Sean J McIlwain, Daojing Wang, Wei Guo, Gary M Diffee, Ying Ge
High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Emily A Chapman, David S Roberts, Timothy N Tiambeng, Jaan Andrews, Man-Di Wang, Emily A Reasoner, Jake A Melby, Brad H Li, Donguk Kim, Andrew J Alpert, Song Jin, Ying Ge
Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics. Nature communications 14 (1) (2023)
Emily A Chapman, David S Roberts, Timothy N Tiambeng, Jaan Andrews, Man-Di Wang, Emily A Reasoner, Jake A Melby, Brad H Li, Donguk Kim, Andrew J Alpert, Song Jin, Ying Ge
Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics. Nature communications 14 (1) (2023)
Kalina J Rossler, Willem J De Lange, Morgan W Mann, Timothy J Aballo, Jake A Melby, Jianhua Zhang, Gina Kim, Elizabeth F Bayne, Yanlong Zhu, Emily T Farrell, Timothy J Kamp, J Carter Ralphe, Ying Ge
Lactate and Immunomagnetic-purified iPSC-derived Cardiomyocytes Generate Comparable Engineered Cardiac Tissue Constructs. bioRxiv : the preprint server for biology (2023)
Holden T Rogers, David S Roberts, Eli J Larson, Jake A Melby, Kalina J Rossler, Austin V Carr, Kyle A Brown, Ying Ge
Comprehensive Characterization of Endogenous Phospholamban Proteoforms Enabled by Photocleavable Surfactant and Top-down Proteomics. Analytical chemistry (2023)
Jake A Melby, Kyle A Brown, Zachery R Gregorich, David S Roberts, Emily A Chapman, Lauren E Ehlers, Zhan Gao, Eli J Larson, Yutong Jin, Justin R Lopez, Jared Hartung, Yanlong Zhu, Sean J McIlwain, Daojing Wang, Wei Guo, Gary M Diffee, Ying Ge
High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Emily A Chapman, David S Roberts, Timothy N Tiambeng, Jaan Andrews, Man-Di Wang, Emily A Reasoner, Jake A Melby, Brad H Li, Donguk Kim, Andrew J Alpert, Song Jin, Ying Ge
Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics. Nature communications 14 (1) (2023)
Emily A Chapman, Timothy J Aballo, Jake A Melby, Tianhua Zhou, Scott J Price, Kalina J Rossler, Ienglam Lei, Paul C Tang, Ying Ge
Defining the Sarcomeric Proteoform Landscape in Ischemic Cardiomyopathy by Top-Down Proteomics. Journal of proteome research 22 (3) (2023)
Emily A Chapman, David S Roberts, Timothy N Tiambeng, Jaan Andrews, Man-Di Wang, Emily A Reasoner, Jake A Melby, Brad H Li, Donguk Kim, Andrew J Alpert, Song Jin, Ying Ge
Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics. Nature communications 14 (1) (2023)
Kalina J Rossler, Willem J De Lange, Morgan W Mann, Timothy J Aballo, Jake A Melby, Jianhua Zhang, Gina Kim, Elizabeth F Bayne, Yanlong Zhu, Emily T Farrell, Timothy J Kamp, J Carter Ralphe, Ying Ge
Lactate and Immunomagnetic-purified iPSC-derived Cardiomyocytes Generate Comparable Engineered Cardiac Tissue Constructs. bioRxiv : the preprint server for biology (2023)
Emily A Chapman, Timothy J Aballo, Jake A Melby, Tianhua Zhou, Scott J Price, Kalina J Rossler, Ienglam Lei, Paul C Tang, Ying Ge
Defining the Sarcomeric Proteoform Landscape in Ischemic Cardiomyopathy by Top-Down Proteomics. Journal of proteome research (2023)
Emily A Chapman, David S Roberts, Timothy N Tiambeng, Jaan Andrews, Man-Di Wang, Emily A Reasoner, Jake A Melby, Brad H Li, Donguk Kim, Andrew J Alpert, Song Jin, Ying Ge
Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics. Nature communications 14 (1) (2023)
Emily A Chapman, Timothy J Aballo, Jake A Melby, Tianhua Zhou, Scott J Price, Kalina J Rossler, Ienglam Lei, Paul C Tang, Ying Ge
Defining the Sarcomeric Proteoform Landscape in Ischemic Cardiomyopathy by Top-Down Proteomics. Journal of proteome research 22 (3) (2023)
Holden T Rogers, David S Roberts, Eli J Larson, Jake A Melby, Kalina J Rossler, Austin V Carr, Kyle A Brown, Ying Ge
Comprehensive Characterization of Endogenous Phospholamban Proteoforms Enabled by Photocleavable Surfactant and Top-down Proteomics. bioRxiv : the preprint server for biology (2023)
Jake A Melby, Kyle A Brown, Zachery R Gregorich, David S Roberts, Emily A Chapman, Lauren E Ehlers, Zhan Gao, Eli J Larson, Yutong Jin, Justin R Lopez, Jared Hartung, Yanlong Zhu, Sean J McIlwain, Daojing Wang, Wei Guo, Gary M Diffee, Ying Ge
High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Emily A Chapman, Timothy J Aballo, Jake A Melby, Tianhua Zhou, Scott J Price, Kalina J Rossler, Ienglam Lei, Paul C Tang, Ying Ge
Defining the Sarcomeric Proteoform Landscape in Ischemic Cardiomyopathy by Top-Down Proteomics. Journal of proteome research 22 (3) (2023)
Emily A Chapman, David S Roberts, Timothy N Tiambeng, Jaan Andrews, Man-Di Wang, Emily A Reasoner, Jake A Melby, Brad H Li, Donguk Kim, Andrew J Alpert, Song Jin, Ying Ge
Structure and dynamics of endogenous protein complexes in human heart tissue captured by native nanoproteomics. bioRxiv : the preprint server for biology (2023)
Holden T Rogers, David S Roberts, Eli J Larson, Jake A Melby, Kalina J Rossler, Austin V Carr, Kyle A Brown, Ying Ge
Comprehensive Characterization of Endogenous Phospholamban Proteoforms Enabled by Photocleavable Surfactant and Top-down Proteomics. bioRxiv : the preprint server for biology (2023)
Emily A Chapman, David S Roberts, Timothy N Tiambeng, Jaan Andrews, Man-Di Wang, Emily A Reasoner, Jake A Melby, Brad H Li, Donguk Kim, Andrew J Alpert, Song Jin, Ying Ge
Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics. Nature communications 14 (1) (2023)
Jake A Melby, Kyle A Brown, Zachery R Gregorich, David S Roberts, Emily A Chapman, Lauren E Ehlers, Zhan Gao, Eli J Larson, Yutong Jin, Justin R Lopez, Jared Hartung, Yanlong Zhu, Sean J McIlwain, Daojing Wang, Wei Guo, Gary M Diffee, Ying Ge
High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Jake A Melby, Kyle A Brown, Zachery R Gregorich, David S Roberts, Emily A Chapman, Lauren E Ehlers, Zhan Gao, Eli J Larson, Yutong Jin, Justin R Lopez, Jared Hartung, Yanlong Zhu, Sean J McIlwain, Daojing Wang, Wei Guo, Gary M Diffee, Ying Ge
High sensitivity top-down proteomics captures single muscle cell heterogeneity in large proteoforms. Proceedings of the National Academy of Sciences of the United States of America 120 (19) (2023)
Eli J Larson, David S Roberts, Jake A Melby, Kevin M Buck, Yanlong Zhu, Shiyue Zhou, Linjie Han, Qunying Zhang, Ying Ge
High-Throughput Multi-attribute Analysis of Antibody-Drug Conjugates Enabled by Trapped Ion Mobility Spectrometry and Top-Down Mass Spectrometry. Analytical chemistry 93 (29) (2021)
Jake A Melby, David S Roberts, Eli J Larson, Kyle A Brown, Elizabeth F Bayne, Song Jin, Ying Ge
Novel Strategies to Address the Challenges in Top-Down Proteomics. Journal of the American Society for Mass Spectrometry 32 (6) (2021)
David S Roberts, Morgan W Mann, Jake A Melby, Eli J Larson, Yanlong Zhu, Allan R Brasier, Song Jin, Ying Ge
Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Native Top-Down Mass Spectrometry. bioRxiv : the preprint server for biology (2021)
Jake A Melby, Willem J de Lange, Jianhua Zhang, David S Roberts, Stanford D Mitchell, Trisha Tucholski, Gina Kim, Andreas Kyrvasilis, Sean J McIlwain, Timothy J Kamp, J Carter Ralphe, Ying Ge
Functionally Integrated Top-Down Proteomics for Standardized Assessment of Human Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues. Journal of proteome research 20 (2) (2021)
David S Roberts, Morgan W Mann, Jake A Melby, Eli J Larson, Yanlong Zhu, Allan R Brasier, Song Jin, Ying Ge
Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Top-Down Mass Spectrometry. Journal of the American Chemical Society 143 (31) (2021)
Timothy J Aballo, David S Roberts, Jake A Melby, Kevin M Buck, Kyle A Brown, Ying Ge
Ultrafast and Reproducible Proteomics from Small Amounts of Heart Tissue Enabled by Azo and timsTOF Pro. Journal of proteome research 20 (8) (2021)
Kyle A Brown, Jake A Melby, David S Roberts, Ying Ge
Top-down proteomics: challenges, innovations, and applications in basic and clinical research. Expert review of proteomics 17 (10) (2020)
Jake A Melby, Yutong Jin, Ziqing Lin, Trisha Tucholski, Zhijie Wu, Zachery R Gregorich, Gary M Diffee, Ying Ge
Top-Down Proteomics Reveals Myofilament Proteoform Heterogeneity among Various Rat Skeletal Muscle Tissues. Journal of proteome research 19 (1) (2019)