Jason W Chin

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 47

Top Topics

Escherichia Coli

Top Venues

Nature chemistry

Science (New York, N.Y.)

Nature biotechnology

This page only lists publications with an associated author ORCID identifier.

Publications

Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature (2024)
Rongzhen Tian, Fabian B H Rehm, Dariusz Czernecki, Yangqi Gu, Jérôme F Zürcher, Kim C Liu, Jason W Chin
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli . Science (New York, N.Y.) 383 (6681) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Daniel L Dunkelmann, Jason W Chin
Engineering Pyrrolysine Systems for Genetic Code Expansion and Reprogramming. Chemical reviews (2024)
Rongzhen Tian, Fabian B H Rehm, Dariusz Czernecki, Yangqi Gu, Jérôme F Zürcher, Kim C Liu, Jason W Chin
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli . Science (New York, N.Y.) 383 (6681) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Rongzhen Tian, Fabian B H Rehm, Dariusz Czernecki, Yangqi Gu, Jérôme F Zürcher, Kim C Liu, Jason W Chin
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli . Science (New York, N.Y.) 383 (6681) (2024)
Juan Luo, Yao Yu, Ke Wang, Sizhe He, Long-Jie Wang, Fangfang Liang, Jason W Chin, Shan Tang
Capturing acyl-enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification. Nature protocols (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Rongzhen Tian, Fabian B H Rehm, Dariusz Czernecki, Yangqi Gu, Jérôme F Zürcher, Kim C Liu, Jason W Chin
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli . Science (New York, N.Y.) 383 (6681) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Rongzhen Tian, Fabian B H Rehm, Dariusz Czernecki, Yangqi Gu, Jérôme F Zürcher, Kim C Liu, Jason W Chin
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli . Science (New York, N.Y.) 383 (6681) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Daniel L Dunkelmann, Carlos Piedrafita Alvira, Alexandre Dickson, Kim C Liu, Thomas S Elliott, Marc Fiedler, Dom Bellini, Andrew Z Zhou, Daniele Cervettini, Jason W Chin
Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism. Nature 625 (7995) (2024)
Adam T Beattie, Daniel L Dunkelmann, Jason W Chin
Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNA Pyl pairs. Nature chemistry (2023)
Jérôme F Zürcher, Askar A Kleefeldt, Louise F H Funke, Jakob Birnbaum, Julius Fredens, Simona Grazioli, Kim C Liu, Martin Spinck, Gianluca Petris, Pierre Murat, Fabian B H Rehm, Julian E Sale, Jason W Chin
Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly. Nature (2023)
Martin Spinck, Carlos Piedrafita Alvira, Wesley E Robertson, Thomas S Elliott, Daniele Cervettini, Daniel de la Torre, Jason W Chin
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles. Nature chemistry 15 (1) (2022)
Martin Spinck, Carlos Piedrafita Alvira, Wesley E Robertson, Thomas S Elliott, Daniele Cervettini, Daniel de la Torre, Jason W Chin
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles. Nature chemistry (2022)
Jérôme F Zürcher, Wesley E Robertson, Tomás Kappes, Gianluca Petris, Thomas S Elliott, George P C Salmond, Jason W Chin
Refactored genetic codes enable bidirectional genetic isolation. Science (New York, N.Y.) 378 (6619) (2022)
Martin Spinck, Carlos Piedrafita Alvira, Wesley E Robertson, Thomas S Elliott, Daniele Cervettini, Daniel de la Torre, Jason W Chin
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles. Nature chemistry 15 (1) (2022)
Martin Spinck, Carlos Piedrafita Alvira, Wesley E Robertson, Thomas S Elliott, Daniele Cervettini, Daniel de la Torre, Jason W Chin
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles. Nature chemistry 15 (1) (2022)
Shan Tang, Adam T Beattie, Lucie Kafkova, Gianluca Petris, Nicolas Huguenin-Dezot, Marc Fiedler, Matthew Freeman, Jason W Chin
Mechanism-based traps enable protease and hydrolase substrate discovery. Nature 602 (7898) (2022)
Martin Spinck, Carlos Piedrafita Alvira, Wesley E Robertson, Thomas S Elliott, Daniele Cervettini, Daniel de la Torre, Jason W Chin
Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles. Nature chemistry 15 (1) (2022)
Charles W Morgan, Ian L Dale, Andrew P Thomas, James Hunt, Jason W Chin
Selective CRAF Inhibition Elicits Transactivation. Journal of the American Chemical Society 143 (12) (2021)
Wesley E Robertson, Louise F H Funke, Daniel de la Torre, Julius Fredens, Thomas S Elliott, Martin Spinck, Yonka Christova, Daniele Cervettini, Franz L Böge, Kim C Liu, Salvador Buse, Sarah L Maslen, George P C Salmond, Jason W Chin
Sense codon reassignment enables viral resistance and encoded polymer synthesis. Science (New York, N.Y.) 372 (6546) (2021)
Wesley E Robertson, Louise F H Funke, Daniel de la Torre, Julius Fredens, Kaihang Wang, Jason W Chin
Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS. Nature protocols 16 (5) (2021)
Daniel L Dunkelmann, Sebastian B Oehm, Adam T Beattie, Jason W Chin
A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design. Nature chemistry 13 (11) (2021)
Daniele Cervettini, Shan Tang, Stephen D Fried, Julian C W Willis, Louise F H Funke, Lucy J Colwell, Jason W Chin
Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs. Nature biotechnology 38 (8) (2020)
Kaihang Wang, Daniel de la Torre, Wesley E Robertson, Jason W Chin
Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly. Science (New York, N.Y.) 365 (6456) (2020)
Daniel de la Torre, Jason W Chin
Reprogramming the genetic code. Nature reviews. Genetics 22 (3) (2020)
Daniel L Dunkelmann, Julian C W Willis, Adam T Beattie, Jason W Chin
Engineered triply orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids. Nature chemistry 12 (6) (2020)
Benjamí Oller-Salvia, Jason W Chin
Efficient Phage Display with Multiple Distinct Non-Canonical Amino Acids Using Orthogonal Ribosome-Mediated Genetic Code Expansion. Angewandte Chemie (International ed. in English) 58 (32) (2019)
Julian C W Willis, Jason W Chin
Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs. Nature chemistry 10 (8) (2018)
Benjamí Oller-Salvia, Gene Kym, Jason W Chin
Rapid and Efficient Generation of Stable Antibody-Drug Conjugates via an Encoded Cyclopropene and an Inverse-Electron-Demand Diels-Alder Reaction. Angewandte Chemie (International ed. in English) 57 (11) (2018)
Martin Baumdick, Márton Gelléri, Chayasith Uttamapinant, Václav Beránek, Jason W Chin, Philippe I H Bastiaens
A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation. Nature communications 9 (1) (2018)
Rohan T Ranasinghe, Martin R Challand, Kristina A Ganzinger, Benjamin W Lewis, Charlotte Softley, Wolfgang H Schmied, Mathew H Horrocks, Nadia Shivji, Jason W Chin, James Spencer, David Klenerman
Detecting RNA base methylations in single cells by in situ hybridization. Nature communications 9 (1) (2018)
Chayasith Uttamapinant, Jonathan D Howe, Kathrin Lang, Václav Beránek, Lloyd Davis, Mohan Mahesh, Nicholas P Barry, Jason W Chin
Correction to "Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins". Journal of the American Chemical Society 140 (42) (2018)
Manjeet Mukherjee, Sarah Sabir, Laura O'Regan, Josephina Sampson, Mark W Richards, Nicolas Huguenin-Dezot, James R Ault, Jason W Chin, Anastasia Zhuravleva, Andrew M Fry, Richard Bayliss
Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release. Science signaling 11 (543) (2018)
Václav Beránek, Julian C W Willis, Jason W Chin
An Evolved Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase/tRNA Pair Is Highly Active and Orthogonal in Mammalian Cells. Biochemistry 58 (5) (2018)
Toke P Krogager, Russell J Ernst, Thomas S Elliott, Laura Calo, Václav Beránek, Ernesto Ciabatti, Maria Grazia Spillantini, Marco Tripodi, Michael H Hastings, Jason W Chin
Labeling and identifying cell-specific proteomes in the mouse brain. Nature biotechnology 36 (2) (2017)
Ardiyanto Liaunardy-Jopeace, Ben L Murton, Mohan Mahesh, Jason W Chin, John R James
Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells. Nature structural & molecular biology 24 (12) (2017)