Jean-Claude Lacaille

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 29

Top Topics

Binding Protein

Intellectual Disability

Prefrontal Cortex

Neuroendocrine Tumors

Top Venues

Molecular brain

Proceedings of the National Academy of Sciences of the United States of America

The Journal of neuroscience : the official journal of the Society for Neuroscience

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Niaz Mahmood, Jung-Hyun Choi, Pei You Wu, Sean W Dooling, Trent A Watkins, Ziying Huang, Jesse Lipman, Hanjie Zhao, Anqi Yang, Jake Silversmith, Yanis Inglebert, Constantinos Koumenis, Vijendra Sharma, Jean-Claude Lacaille, Wayne S Sossin, Arkady Khoutorsky, R Anne McKinney, Mauro Costa-Mattioli, Nahum Sonenberg
The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner. Proceedings of the National Academy of Sciences of the United States of America 121 (31) (2024)
Niaz Mahmood, Jung-Hyun Choi, Pei You Wu, Sean W Dooling, Trent A Watkins, Ziying Huang, Jesse Lipman, Hanjie Zhao, Anqi Yang, Jake Silversmith, Yanis Inglebert, Constantinos Koumenis, Vijendra Sharma, Jean-Claude Lacaille, Wayne S Sossin, Arkady Khoutorsky, R Anne McKinney, Mauro Costa-Mattioli, Nahum Sonenberg
The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner. Proceedings of the National Academy of Sciences of the United States of America 121 (31) (2024)
Niaz Mahmood, Jung-Hyun Choi, Pei You Wu, Sean W Dooling, Trent A Watkins, Ziying Huang, Jesse Lipman, Hanjie Zhao, Anqi Yang, Jake Silversmith, Yanis Inglebert, Constantinos Koumenis, Vijendra Sharma, Jean-Claude Lacaille, Wayne S Sossin, Arkady Khoutorsky, R Anne McKinney, Mauro Costa-Mattioli, Nahum Sonenberg
The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner. Proceedings of the National Academy of Sciences of the United States of America 121 (31) (2024)
Lara Eid, Ludmilla Lokmane, Praveen K Raju, Samuel Boris Tene Tadoum, Xiao Jiang, Karolanne Toulouse, Alexis Lupien-Meilleur, François Charron-Ligez, Asmaa Toumi, Stéphanie Backer, Mathieu Lachance, Marisol Lavertu-Jolin, Marie Montseny, Jean-Claude Lacaille, Evelyne Bloch-Gallego, Elsa Rossignol
Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons. Molecular psychiatry (2024)
Niaz Mahmood, Jung-Hyun Choi, Pei You Wu, Sean W Dooling, Trent A Watkins, Ziying Huang, Jesse Lipman, Hanjie Zhao, Anqi Yang, Jake Silversmith, Yanis Inglebert, Constantinos Koumenis, Vijendra Sharma, Jean-Claude Lacaille, Wayne S Sossin, Arkady Khoutorsky, R Anne McKinney, Mauro Costa-Mattioli, Nahum Sonenberg
The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner. Proceedings of the National Academy of Sciences of the United States of America 121 (31) (2024)
Vijendra Sharma, Mauricio M Oliveira, Rapita Sood, Abdessattar Khlaifia, Danning Lou, Mehdi Hooshmandi, Tzu-Yu Hung, Niaz Mahmood, Maya Reeves, David Ho-Tieng, Noah Cohen, Po-Chieh Cheng, Mir Munir A Rahim, Masha Prager-Khoutorsky, Alexandre Rosa Campos, Kobi Rosenblum, Jean-Claude Lacaille, Arkady Khoutorsky, Eric Klann, Nahum Sonenberg
mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory. Proceedings of the National Academy of Sciences of the United States of America 120 (49) (2023)
Abdessattar Khlaifia, Vidya Jadhav, Marc Danik, Théo Badra, Martin Berryer, Alexandre Dionne-Laporte, Bidisha Chattopadhyaya, Graziella Di Cristo, Jean-Claude Lacaille, Jacques L Michaud
Syngap1 disruption induced by recombination between inverted loxP sites is associated with hippocampal interneuron dysfunction. eNeuro (2023)
François-Xavier Michon, Isabel Laplante, Anthony Bosson, Richard Robitaille, Jean-Claude Lacaille
mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons. Molecular brain 16 (1) (2023)
Eve Honoré, Jean-Claude Lacaille
Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses. Molecular brain 15 (1) (2022)
Ève Honoré, Inês Belo do Nascimento, Isabel Laplante, Jean-Claude Lacaille
Stimulation of protein synthesis by optogenetic and chemical induction of excitatory synaptic plasticity in hippocampal somatostatin interneurons. Molecular brain 15 (1) (2022)
Eve Honoré, Jean-Claude Lacaille
Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses. Molecular brain 15 (1) (2022)
Abdessattar Khlaifia, Eve Honoré, Julien Artinian, Isabel Laplante, Jean-Claude Lacaille
mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination. Molecular brain 15 (1) (2022)
Eve Honoré, Jean-Claude Lacaille
Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses. Molecular brain 15 (1) (2022)
Eve Honoré, Jean-Claude Lacaille
Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses. Molecular brain 15 (1) (2022)
Eve Honoré, Jean-Claude Lacaille
Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses. Molecular brain 15 (1) (2022)
Alexis Lupien-Meilleur, Xiao Jiang, Mathieu Lachance, Vincent Taschereau-Dumouchel, Louise Gagnon, Catherine Vanasse, Jean-Claude Lacaille, Elsa Rossignol
Reversing frontal disinhibition rescues behavioural deficits in models of CACNA1A-associated neurodevelopment disorders. Molecular psychiatry (2021)
Anne-Sophie Racine, François-Xavier Michon, Isabel Laplante, Jean-Claude Lacaille
Somatostatin contributes to long-term potentiation at excitatory synapses onto hippocampal somatostatinergic interneurons. Molecular brain 14 (1) (2021)
Vijendra Sharma, Rapita Sood, Danning Lou, Tzu-Yu Hung, Maxime Lévesque, Yelin Han, Jeremy Y Levett, Peng Wang, Shravan Murthy, Shannon Tansley, Siyan Wang, Nadeem Siddiqui, Soroush Tahmasebi, Kobi Rosenblum, Massimo Avoli, Jean-Claude Lacaille, Nahum Sonenberg, Arkady Khoutorsky
4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold. Proceedings of the National Academy of Sciences of the United States of America 118 (15) (2021)
Argel Aguilar-Valles, Danilo De Gregorio, Edna Matta-Camacho, Mohammad J Eslamizade, Abdessattar Khlaifia, Agnieszka Skaleka, Martha Lopez-Canul, Angelica Torres-Berrio, Sara Bermudez, Gareth M Rurak, Stephanie Simard, Natalina Salmaso, Gabriella Gobbi, Jean-Claude Lacaille, Nahum Sonenberg
Antidepressant actions of ketamine engage cell-specific translation via eIF4E. Nature 590 (7845) (2020)
André Kougioumoutzakis, Joe Guillaume Pelletier, Isabel Laplante, Abdessattar Khlaifia, Jean-Claude Lacaille
TRPC1 mediates slow excitatory synaptic transmission in hippocampal oriens/alveus interneurons. Molecular brain 13 (1) (2020)
Nabila Haji, Ilse Riebe, Argel Aguilar-Valles, Julien Artinian, Isabel Laplante, Jean-Claude Lacaille
Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice. Molecular autism 11 (1) (2020)
Vijendra Sharma, Rapita Sood, Abdessattar Khlaifia, Mohammad Javad Eslamizade, Tzu-Yu Hung, Danning Lou, Azam Asgarihafshejani, Maya Lalzar, Stephen J Kiniry, Matthew P Stokes, Noah Cohen, Alissa J Nelson, Kathryn Abell, Anthony P Possemato, Shunit Gal-Ben-Ari, Vinh T Truong, Peng Wang, Adonis Yiannakas, Fatemeh Saffarzadeh, Augusto Claudio Cuello, Karim Nader, Alexandre Rosa Campos, Mauro Costa-Mattioli, Pavel V Baranov, Albert Quintana, Elisenda Sanz, Arkady Khoutorsky, Jean-Claude Lacaille, Kobi Rosenblum, Nahum Sonenberg
eIF2α controls memory consolidation via excitatory and somatostatin neurons. Nature 586 (7829) (2020)
Julien Artinian, Alexander Jordan, Abdessattar Khlaifia, Eve Honoré, Alexandre La Fontaine, Anne-Sophie Racine, Isabel Laplante, Jean-Claude Lacaille
Regulation of Hippocampal Memory by mTORC1 in Somatostatin Interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience 39 (43) (2019)
Xiao Jiang, Praveen K Raju, Nazzareno D'Avanzo, Mathieu Lachance, Julie Pepin, François Dubeau, Wendy G Mitchell, Luis E Bello-Espinosa, Tyler M Pierson, Berge A Minassian, Jean-Claude Lacaille, Elsa Rossignol
Both gain-of-function and loss-of-function de novo CACNA1A mutations cause severe developmental epileptic encephalopathies in the spectrum of Lennox-Gastaut syndrome. Epilepsia 60 (9) (2019)
Marco Matos, Anthony Bosson, Ilse Riebe, Clare Reynell, Joanne Vallée, Isabel Laplante, Aude Panatier, Richard Robitaille, Jean-Claude Lacaille
Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells. Nature communications 9 (1) (2018)
Argel Aguilar-Valles, Nabila Haji, Danilo De Gregorio, Edna Matta-Camacho, Mohammad J Eslamizade, Jelena Popić, Vijendra Sharma, Ruifeng Cao, Christoph Rummel, Arnaud Tanti, Shane Wiebe, Nicolas Nuñez, Stefano Comai, Robert Nadon, Giamal Luheshi, Naguib Mechawar, Gustavo Turecki, Jean-Claude Lacaille, Gabriella Gobbi, Nahum Sonenberg
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E. Nature communications 9 (1) (2018)
Tyson Ernst Graber, Erika Freemantle, Mina N Anadolu, Sarah Hébert-Seropian, Robyn L MacAdam, Unkyung Shin, Huy-Dung Hoang, Tommy Alain, Jean-Claude Lacaille, Wayne S Sossin
UPF1 Governs Synaptic Plasticity through Association with a STAU2 RNA Granule. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (38) (2017)
Ilse Gantois, Arkady Khoutorsky, Jelena Popic, Argel Aguilar-Valles, Erika Freemantle, Ruifeng Cao, Vijendra Sharma, Tine Pooters, Anmol Nagpal, Agnieszka Skalecka, Vinh T Truong, Shane Wiebe, Isabelle A Groves, Seyed Mehdi Jafarnejad, Clément Chapat, Elizabeth A McCullagh, Karine Gamache, Karim Nader, Jean-Claude Lacaille, Christos G Gkogkas, Nahum Sonenberg
Metformin ameliorates core deficits in a mouse model of fragile X syndrome. Nature medicine 23 (6) (2017)
Martin H Berryer, Bidisha Chattopadhyaya, Paul Xing, Ilse Riebe, Ciprian Bosoi, Nathalie Sanon, Judith Antoine-Bertrand, Maxime Lévesque, Massimo Avoli, Fadi F Hamdan, Lionel Carmant, Nathalie Lamarche-Vane, Jean-Claude Lacaille, Jacques L Michaud, Graziella Di Cristo
Decrease of SYNGAP1 in GABAergic cells impairs inhibitory synapse connectivity, synaptic inhibition and cognitive function. Nature communications 7 (2016)
Argel Aguilar-Valles, Edna Matta-Camacho, Arkady Khoutorsky, Christos G Gkogkas, Karim Nader, Jean-Claude Lacaille, Nahum Sonenberg
Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2. The Journal of neuroscience : the official journal of the Society for Neuroscience 35 (31) (2015)