Jean-François Trempe

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 31

Top Venues

PloS one

Nature communications

Life science alliance

PNAS nexus

Université McGill

McGill University (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Université McGill Jun 01 2019

Canada

Associate Professor :: Pharmacology & Therapeutics

McGill University Aug 01 2013 - May 31 2019

Canada

Assistant Professor :: Pharmacology & Therapeutics

Montreal Neurological Institute and Hospital Sep 01 2010 - Jul 31 2013

Canada

Postdoctoral fellow :: Neurology & Neurosurgery

McGill University Jan 01 2007 - Aug 31 2010

Canada

Postdoctoral fellow :: Biochemistry

Education History

McGill University Sep 01 2000 - Aug 31 2002

Canada

MSC :: Biochemistry

McGill University Sep 01 1997 - May 01 2000

Canada

BSC :: Biochemistry

Publications

Anshu Saran, Hey-Min Kim, Ireland Manning, Mark A Hancock, Claus Schmitz, Mariusz Madej, Jan Potempa, Maria Sola, Jean-François Trempe, Yongtao Zhu, Mary Ellen Davey, Natalie Zeytuni
Unveiling the Molecular Mechanisms of the Type-IX Secretion System's Response Regulator: Structural and Functional Insights. bioRxiv : the preprint server for biology (2024)
Emily Banks, Vincent Francis, Sheng-Jia Lin, Fares Kharfallah, Vladimir S Fonov, Maxime Levesque, Chanshuai Han, Gopinath Kulasekaran, Marius Tuznik, Armin Bayati, Reem Al-Khater, Fowzan Sami Alkuraya, Loukas Argyriou, Meisam Babaei, Melanie Bahlo, Behnoosh Bakhshoodeh, Eileen Barr, Lauren Bartik, Mahmoud Bassiony, Miriam Bertrand, Dominique Braun, Rebecca Buchert, Mauro Budetta, Maxime Cadieux-Dion, Daniel G Calame, Heidi Cope, Donna Cushing, Stephanie Efthymiou, Marwa A Elmaksoud, Huda G El Said, Tawfiq Froukh, Harinder K Gill, Joseph G Gleeson, Laura Gogoll, Elaine S-Y Goh, Vykuntaraju K Gowda, Tobias B Haack, Mais O Hashem, Stefan Hauser, Trevor L Hoffman, Jacob S Hogue, Akimoto Hosokawa, Henry Houlden, Kevin Huang, Stephanie Huynh, Ehsan G Karimiani, Silke Kaulfuß, G Christoph Korenke, Amy Kritzer, Hane Lee, James R. Lupski, Elysa J Marco, Kirsty McWalter, Arakel Minassian, Berge A Minassian, David Murphy, Juanita Neira-Fresneda, Hope Northrup, Denis Nyaga, Barbara Oehl-Jaschkowitz, Matthew Osmond, Richard Person, Davut Pehlivan, Cassidy Petree, Lynette G Sadleir, Carol Saunders, Ludger Schoels, Vandana Shashi, Rebecca C Spillman, Varunvenkat M Srinivasan, Paria N Torbati, Tulay Tos, null null, Maha S Zaki, Dihong Zhou, Christiane Zweier, Jean-François Trempe, Thomas Martin Durcan, Ziv Gan-Or, Massimo Avoli, César Augusto Pinheiro Ferreira Alves, Guarav K Varshney, Reza Maroofian, David A Rudko, Peter S McPherson
Loss of symmetric cell division of apical neural progenitors drives DENND5A -related developmental and epileptic encephalopathy. medRxiv : the preprint server for health sciences (2024)
Emily Banks, Vincent Francis, Sheng-Jia Lin, Fares Kharfallah, Vladimir S Fonov, Maxime Lévesque, Chanshuai Han, Gopinath Kulasekaran, Marius Tuznik, Armin Bayati, Reem A Alkhater, Fowzan Sami Alkuraya, Loukas Argyriou, Meisam Babaei, Melanie Bahlo, Behnoosh Bakhshoodeh, Eileen Barr, Lauren Bartik, Mahmoud Bassiony, Miriam Bertrand, Dominique Braun, Rebecca Buchert, Mauro Budetta, Maxime Cadieux-Dion, Daniel G Calame, Heidi Cope, Donna Cushing, Stephanie Efthymiou, Marwa Abd Elmaksoud, Huda G El Said, Tawfiq Froukh, Harinder K Gill, Joseph G Gleeson, Laura Gogoll, Elaine Suk-Ying Goh, Vykuntaraju K Gowda, Tobias B Haack, Mais O Hashem, Stefan Hauser, Trevor L Hoffman, Jacob S Hogue, Akimoto Hosokawa, Henry Houlden, Kevin Huang, Stephanie Huynh, Ehsan G Karimiani, Silke Kaulfuß, G Christoph Korenke, Amy Kritzer, Hane Lee, James R. Lupski, Elysa J Marco, Kirsty McWalter, Arakel Minassian, Berge A Minassian, David Murphy, Juanita Neira-Fresneda, Hope Northrup, Denis M Nyaga, Barbara Oehl-Jaschkowitz, Matthew Osmond, Richard Person, Davut Pehlivan, Cassidy Petree, Lynette G Sadleir, Carol J Saunders, Ludger Schoels, Vandana Shashi, Rebecca C Spillmann, Varunvenkat M Srinivasan, Paria N Torbati, Tulay Tos, null null, Maha Saad Zaki, Dihong Zhou, Christiane Zweier, Jean-François Trempe, Thomas M Durcan, Ziv Gan Or, Massimo Avoli, Cesar Alves, Guarav K Varshney, Reza Maroofian, David A Rudko, Peter S McPherson
Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy. Nature communications 15 (1) (2024)
Anshu Saran, Hey-Min Kim, Ireland Manning, Mark A Hancock, Claus Schmitz, Mariusz Madej, Jan Potempa, Maria Sola, Jean-François Trempe, Yongtao Zhu, Mary Ellen Davey, Natalie Zeytuni
Unveiling the Molecular Mechanisms of the Type-IX Secretion System's Response Regulator: Structural and Functional Insights. bioRxiv : the preprint server for biology (2024)
Anshu Saran, Hey-Min Kim, Ireland Manning, Mark A Hancock, Claus Schmitz, Mariusz Madej, Jan Potempa, Maria Sol Formula See Text, Jean-François Trempe, Yongtao Zhu, Mary Ellen Davey, Natalie Zeytuni
Unveiling the molecular mechanisms of the type IX secretion system's response regulator: Structural and functional insights. PNAS nexus 3 (8) (2024)
Emily Banks, Vincent Francis, Sheng-Jia Lin, Fares Kharfallah, Vladimir S Fonov, Maxime Levesque, Chanshuai Han, Gopinath Kulasekaran, Marius Tuznik, Armin Bayati, Reem Al-Khater, Fowzan Sami Alkuraya, Loukas Argyriou, Meisam Babaei, Melanie Bahlo, Behnoosh Bakhshoodeh, Eileen Barr, Lauren Bartik, Mahmoud Bassiony, Miriam Bertrand, Dominique Braun, Rebecca Buchert, Mauro Budetta, Maxime Cadieux-Dion, Daniel G Calame, Heidi Cope, Donna Cushing, Stephanie Efthymiou, Marwa A Elmaksoud, Huda G El Said, Tawfiq Froukh, Harinder K Gill, Joseph G Gleeson, Laura Gogoll, Elaine S-Y Goh, Vykuntaraju K Gowda, Tobias B Haack, Mais O Hashem, Stefan Hauser, Trevor L Hoffman, Jacob S Hogue, Akimoto Hosokawa, Henry Houlden, Kevin Huang, Stephanie Huynh, Ehsan G Karimiani, Silke Kaulfuß, G Christoph Korenke, Amy Kritzer, Hane Lee, James R. Lupski, Elysa J Marco, Kirsty McWalter, Arakel Minassian, Berge A Minassian, David Murphy, Juanita Neira-Fresneda, Hope Northrup, Denis Nyaga, Barbara Oehl-Jaschkowitz, Matthew Osmond, Richard Person, Davut Pehlivan, Cassidy Petree, Lynette G Sadleir, Carol Saunders, Ludger Schoels, Vandana Shashi, Rebecca C Spillman, Varunvenkat M Srinivasan, Paria N Torbati, Tulay Tos, null null, Maha S Zaki, Dihong Zhou, Christiane Zweier, Jean-François Trempe, Thomas Martin Durcan, Ziv Gan-Or, Massimo Avoli, César Augusto Pinheiro Ferreira Alves, Guarav K Varshney, Reza Maroofian, David A Rudko, Peter S McPherson
Loss of symmetric cell division of apical neural progenitors drives DENND5A -related developmental and epileptic encephalopathy. medRxiv : the preprint server for health sciences (2024)
Anshu Saran, Hey-Min Kim, Ireland Manning, Mark A Hancock, Claus Schmitz, Mariusz Madej, Jan Potempa, Maria Sol Formula See Text, Jean-François Trempe, Yongtao Zhu, Mary Ellen Davey, Natalie Zeytuni
Unveiling the molecular mechanisms of the type IX secretion system's response regulator: Structural and functional insights. PNAS nexus 3 (8) (2024)
Emily Banks, Vincent Francis, Sheng-Jia Lin, Fares Kharfallah, Vladimir S Fonov, Maxime Lévesque, Chanshuai Han, Gopinath Kulasekaran, Marius Tuznik, Armin Bayati, Reem A Alkhater, Fowzan Sami Alkuraya, Loukas Argyriou, Meisam Babaei, Melanie Bahlo, Behnoosh Bakhshoodeh, Eileen Barr, Lauren Bartik, Mahmoud Bassiony, Miriam Bertrand, Dominique Braun, Rebecca Buchert, Mauro Budetta, Maxime Cadieux-Dion, Daniel G Calame, Heidi Cope, Donna Cushing, Stephanie Efthymiou, Marwa Abd Elmaksoud, Huda G El Said, Tawfiq Froukh, Harinder K Gill, Joseph G Gleeson, Laura Gogoll, Elaine Suk-Ying Goh, Vykuntaraju K Gowda, Tobias B Haack, Mais O Hashem, Stefan Hauser, Trevor L Hoffman, Jacob S Hogue, Akimoto Hosokawa, Henry Houlden, Kevin Huang, Stephanie Huynh, Ehsan G Karimiani, Silke Kaulfuß, G Christoph Korenke, Amy Kritzer, Hane Lee, James R. Lupski, Elysa J Marco, Kirsty McWalter, Arakel Minassian, Berge A Minassian, David Murphy, Juanita Neira-Fresneda, Hope Northrup, Denis M Nyaga, Barbara Oehl-Jaschkowitz, Matthew Osmond, Richard Person, Davut Pehlivan, Cassidy Petree, Lynette G Sadleir, Carol J Saunders, Ludger Schoels, Vandana Shashi, Rebecca C Spillmann, Varunvenkat M Srinivasan, Paria N Torbati, Tulay Tos, null null, Maha Saad Zaki, Dihong Zhou, Christiane Zweier, Jean-François Trempe, Thomas M Durcan, Ziv Gan Or, Massimo Avoli, Cesar Alves, Guarav K Varshney, Reza Maroofian, David A Rudko, Peter S McPherson
Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy. Nature communications 15 (1) (2024)
Véronique Sauvé, Eric Stefan, Nathalie Croteau, Thomas Goiran, Rayan Fakih, Nupur Bansal, Adelajda Hadzipasic, Jing Fang, Paramasivam Murugan, Shimin Chen, Edward A Fon, Warren D Hirst, Laura F Silvian, Jean-François Trempe, Kalle Gehring
Activation of parkin by a molecular glue. Nature communications 15 (1) (2024)
Emily Banks, Vincent Francis, Sheng-Jia Lin, Fares Kharfallah, Vladimir S Fonov, Maxime Levesque, Chanshuai Han, Gopinath Kulasekaran, Marius Tuznik, Armin Bayati, Reem Al-Khater, Fowzan Sami Alkuraya, Loukas Argyriou, Meisam Babaei, Melanie Bahlo, Behnoosh Bakhshoodeh, Eileen Barr, Lauren Bartik, Mahmoud Bassiony, Miriam Bertrand, Dominique Braun, Rebecca Buchert, Mauro Budetta, Maxime Cadieux-Dion, Daniel G Calame, Heidi Cope, Donna Cushing, Stephanie Efthymiou, Marwa A Elmaksoud, Huda G El Said, Tawfiq Froukh, Harinder K Gill, Joseph G Gleeson, Laura Gogoll, Elaine S-Y Goh, Vykuntaraju K Gowda, Tobias B Haack, Mais O Hashem, Stefan Hauser, Trevor L Hoffman, Jacob S Hogue, Akimoto Hosokawa, Henry Houlden, Kevin Huang, Stephanie Huynh, Ehsan G Karimiani, Silke Kaulfuß, G Christoph Korenke, Amy Kritzer, Hane Lee, James R. Lupski, Elysa J Marco, Kirsty McWalter, Arakel Minassian, Berge A Minassian, David Murphy, Juanita Neira-Fresneda, Hope Northrup, Denis Nyaga, Barbara Oehl-Jaschkowitz, Matthew Osmond, Richard Person, Davut Pehlivan, Cassidy Petree, Lynette G Sadleir, Carol Saunders, Ludger Schoels, Vandana Shashi, Rebecca C Spillman, Varunvenkat M Srinivasan, Paria N Torbati, Tulay Tos, null null, Maha S Zaki, Dihong Zhou, Christiane Zweier, Jean-François Trempe, Thomas Martin Durcan, Ziv Gan-Or, Massimo Avoli, César Augusto Pinheiro Ferreira Alves, Guarav K Varshney, Reza Maroofian, David A Rudko, Peter S McPherson
Loss of symmetric cell division of apical neural progenitors drives DENND5A -related developmental and epileptic encephalopathy. medRxiv : the preprint server for health sciences (2024)
Anshu Saran, Hey-Min Kim, Ireland Manning, Mark A Hancock, Claus Schmitz, Mariusz Madej, Jan Potempa, Maria Sola, Jean-François Trempe, Yongtao Zhu, Mary Ellen Davey, Natalie Zeytuni
Unveiling the Molecular Mechanisms of the Type-IX Secretion System's Response Regulator: Structural and Functional Insights. bioRxiv : the preprint server for biology (2024)
Anshu Saran, Hey-Min Kim, Ireland Manning, Mark A Hancock, Claus Schmitz, Mariusz Madej, Jan Potempa, Maria Sol Formula See Text, Jean-François Trempe, Yongtao Zhu, Mary Ellen Davey, Natalie Zeytuni
Unveiling the molecular mechanisms of the type IX secretion system's response regulator: Structural and functional insights. PNAS nexus 3 (8) (2024)
Emily Banks, Vincent Francis, Sheng-Jia Lin, Fares Kharfallah, Vladimir S Fonov, Maxime Lévesque, Chanshuai Han, Gopinath Kulasekaran, Marius Tuznik, Armin Bayati, Reem A Alkhater, Fowzan Sami Alkuraya, Loukas Argyriou, Meisam Babaei, Melanie Bahlo, Behnoosh Bakhshoodeh, Eileen Barr, Lauren Bartik, Mahmoud Bassiony, Miriam Bertrand, Dominique Braun, Rebecca Buchert, Mauro Budetta, Maxime Cadieux-Dion, Daniel G Calame, Heidi Cope, Donna Cushing, Stephanie Efthymiou, Marwa Abd Elmaksoud, Huda G El Said, Tawfiq Froukh, Harinder K Gill, Joseph G Gleeson, Laura Gogoll, Elaine Suk-Ying Goh, Vykuntaraju K Gowda, Tobias B Haack, Mais O Hashem, Stefan Hauser, Trevor L Hoffman, Jacob S Hogue, Akimoto Hosokawa, Henry Houlden, Kevin Huang, Stephanie Huynh, Ehsan G Karimiani, Silke Kaulfuß, G Christoph Korenke, Amy Kritzer, Hane Lee, James R. Lupski, Elysa J Marco, Kirsty McWalter, Arakel Minassian, Berge A Minassian, David Murphy, Juanita Neira-Fresneda, Hope Northrup, Denis M Nyaga, Barbara Oehl-Jaschkowitz, Matthew Osmond, Richard Person, Davut Pehlivan, Cassidy Petree, Lynette G Sadleir, Carol J Saunders, Ludger Schoels, Vandana Shashi, Rebecca C Spillmann, Varunvenkat M Srinivasan, Paria N Torbati, Tulay Tos, null null, Maha Saad Zaki, Dihong Zhou, Christiane Zweier, Jean-François Trempe, Thomas M Durcan, Ziv Gan Or, Massimo Avoli, Cesar Alves, Guarav K Varshney, Reza Maroofian, David A Rudko, Peter S McPherson
Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy. Nature communications 15 (1) (2024)
Emily Banks, Vincent Francis, Sheng-Jia Lin, Fares Kharfallah, Vladimir S Fonov, Maxime Lévesque, Chanshuai Han, Gopinath Kulasekaran, Marius Tuznik, Armin Bayati, Reem A Alkhater, Fowzan Sami Alkuraya, Loukas Argyriou, Meisam Babaei, Melanie Bahlo, Behnoosh Bakhshoodeh, Eileen Barr, Lauren Bartik, Mahmoud Bassiony, Miriam Bertrand, Dominique Braun, Rebecca Buchert, Mauro Budetta, Maxime Cadieux-Dion, Daniel G Calame, Heidi Cope, Donna Cushing, Stephanie Efthymiou, Marwa Abd Elmaksoud, Huda G El Said, Tawfiq Froukh, Harinder K Gill, Joseph G Gleeson, Laura Gogoll, Elaine Suk-Ying Goh, Vykuntaraju K Gowda, Tobias B Haack, Mais O Hashem, Stefan Hauser, Trevor L Hoffman, Jacob S Hogue, Akimoto Hosokawa, Henry Houlden, Kevin Huang, Stephanie Huynh, Ehsan G Karimiani, Silke Kaulfuß, G Christoph Korenke, Amy Kritzer, Hane Lee, James R. Lupski, Elysa J Marco, Kirsty McWalter, Arakel Minassian, Berge A Minassian, David Murphy, Juanita Neira-Fresneda, Hope Northrup, Denis M Nyaga, Barbara Oehl-Jaschkowitz, Matthew Osmond, Richard Person, Davut Pehlivan, Cassidy Petree, Lynette G Sadleir, Carol J Saunders, Ludger Schoels, Vandana Shashi, Rebecca C Spillmann, Varunvenkat M Srinivasan, Paria N Torbati, Tulay Tos, null null, Maha Saad Zaki, Dihong Zhou, Christiane Zweier, Jean-François Trempe, Thomas M Durcan, Ziv Gan Or, Massimo Avoli, Cesar Alves, Guarav K Varshney, Reza Maroofian, David A Rudko, Peter S McPherson
Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy. Nature communications 15 (1) (2024)
Andrew N Bayne, Jing Dong, Saeid Amiri, Sali M K Farhan, Jean-François Trempe
MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures. PloS one 18 (4) (2023)
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul M K Muqit, Jean-François Trempe
Structure-based design and characterization of Parkin-activating mutations. Life science alliance 6 (6) (2023)
Andrew N Bayne, Jing Dong, Saeid Amiri, Sali M K Farhan, Jean-François Trempe
MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures. PloS one 18 (4) (2023)
Andrew N Bayne, Jing Dong, Saeid Amiri, Sali M K Farhan, Jean-François Trempe
MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures. PloS one 18 (4) (2023)
Andrew N Bayne, Jing Dong, Saeid Amiri, Sali M K Farhan, Jean-François Trempe
MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures. PloS one 18 (4) (2023)
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul M K Muqit, Jean-François Trempe
Structure-based design and characterization of Parkin-activating mutations. Life science alliance 6 (6) (2023)
Andrew N Bayne, Jing Dong, Saeid Amiri, Sali M K Farhan, Jean-François Trempe
MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures. PloS one 18 (4) (2023)
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul M K Muqit, Jean-François Trempe
Structure-based design and characterization of Parkin-activating mutations. Life science alliance 6 (6) (2023)
Andrew N Bayne, Jing Dong, Saeid Amiri, Sali M K Farhan, Jean-François Trempe
MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures. PloS one 18 (4) (2023)
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul M K Muqit, Jean-François Trempe
Structure-based design and characterization of Parkin-activating mutations. Life science alliance 6 (6) (2023)
Andrew N Bayne, Jing Dong, Saeid Amiri, Sali M K Farhan, Jean-François Trempe
MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures. PloS one 18 (4) (2023)
Marta Vranas, Yang Lu, Shafqat Rasool, Nathalie Croteau, Jonathan D Krett, Véronique Sauvé, Kalle Gehring, Edward A Fon, Thomas Martin Durcan, Jean-François Trempe
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria. Open biology 12 (1) (2022)
Ahmad Abdelzaher Zaki Khalifa, Muneyoshi Ichikawa, Daniel Dai, Shintaroh Kubo, Corbin Steven Black, Katya Peri, Thomas S McAlear, Simon Veyron, Shun Kai Yang, Javier Vargas, Susanne Bechstedt, Jean-François Trempe, Khanh Huy Bui
The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications. eLife 9 (2020)
Andrew N Bayne, Jean-François Trempe
Mechanisms of PINK1, ubiquitin and Parkin interactions in mitochondrial quality control and beyond. Cellular and molecular life sciences : CMLS 76 (23) (2019)
Shafqat Rasool, Naoto Soya, Luc Truong, Nathalie Croteau, Gergely L Lukacs, Jean-François Trempe
PINK1 autophosphorylation is required for ubiquitin recognition. EMBO reports 19 (4) (2018)
Véronique Sauvé, George Sung, Naoto Soya, Guennadi Kozlov, Nina Blaimschein, Lis Schwartz Miotto, Jean-François Trempe, Gergely L Lukacs, Kalle Gehring
Mechanism of parkin activation by phosphorylation. Nature structural & molecular biology 25 (7) (2018)
Shafqat Rasool, Jean-François Trempe
New insights into the structure of PINK1 and the mechanism of ubiquitin phosphorylation. Critical reviews in biochemistry and molecular biology 53 (5) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jean-François Trempe