Edward A Fon (Edward Fon)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 33

Top Venues

medRxiv : the preprint server for health sciences

Proceedings of the National Academy of Sciences of the United States of America

Brain : a journal of neurology

Life science alliance

Montreal Neurological Institute and Hospital

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Montreal Neurological Institute and Hospital Jul 01 1999

Canada

Professor :: Neurology and Neurosurgery, McGill University

Publications

Mohamed A Eldeeb, Andrew N Bayne, Armaan Fallahi, Thomas Goiran, Emma J MacDougall, Andrea Soumbasis, Cornelia E Zorca, Jace-Jones Tabah, Rhalena A Thomas, Nathan Karpilovsky, Meghna Mathur, Thomas M Durcan, Jean-François Trempe, Edward A Fon
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress. Proceedings of the National Academy of Sciences of the United States of America 121 (10) (2024)
Mohamed A Eldeeb, Andrew N Bayne, Armaan Fallahi, Thomas Goiran, Emma J MacDougall, Andrea Soumbasis, Cornelia E Zorca, Jace-Jones Tabah, Rhalena A Thomas, Nathan Karpilovsky, Meghna Mathur, Thomas M Durcan, Jean-François Trempe, Edward A Fon
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress. Proceedings of the National Academy of Sciences of the United States of America 121 (10) (2024)
Alex I Wiesman, Victoria Madge, Edward A Fon, Alain Dagher, Lars Lau Raket, Sylvain Baillet, null null, null null
Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. medRxiv : the preprint server for health sciences (2024)
Alex I Wiesman, Victoria Madge, Edward A Fon, Alain Dagher, Lars Lau Raket, Sylvain Baillet, null null, null null
Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. medRxiv : the preprint server for health sciences (2024)
Alex I Wiesman, Victoria Madge, Edward A Fon, Alain Dagher, Lars Lau Raket, Sylvain Baillet, null null
Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. Brain : a journal of neurology (2024)
Alex I Wiesman, Victoria Madge, Edward A Fon, Alain Dagher, Lars Lau Raket, Sylvain Baillet, null null, null null
Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. medRxiv : the preprint server for health sciences (2024)
Mohamed A Eldeeb, Andrew N Bayne, Armaan Fallahi, Thomas Goiran, Emma J MacDougall, Andrea Soumbasis, Cornelia E Zorca, Jace-Jones Tabah, Rhalena A Thomas, Nathan Karpilovsky, Meghna Mathur, Thomas M Durcan, Jean-François Trempe, Edward A Fon
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress. Proceedings of the National Academy of Sciences of the United States of America 121 (10) (2024)
Jace Jones-Tabah, Kathy He, Konstantin Senkevich, Nathan Karpilovsky, Ghislaine Deyab, Yuting Cousineau, Daria Nikanorova, Taylor Goldsmith, Esther Del-Cid Pellitero, Carol Xq Chen, Wen Luo, Zhipeng You, Narges Abdian, Isabella Pietrantonio, Thomas Goiran, Jamil Ahmad, Jennifer A Ruskey, Farnaz Asayesh, Dan Spiegelman, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupre, Irina Miliukhina, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Lior Greenbaum, Sharon HassinBaer, Roy N Alcalay, Austen Milnerwood, Thomas M Durcan, Ziv Gan-Or, Edward A Fon
The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons. Research square (2024)
Véronique Sauvé, Eric Stefan, Nathalie Croteau, Thomas Goiran, Rayan Fakih, Nupur Bansal, Adelajda Hadzipasic, Jing Fang, Paramasivam Murugan, Shimin Chen, Edward A Fon, Warren D Hirst, Laura F Silvian, Jean-François Trempe, Kalle Gehring
Activation of parkin by a molecular glue. Nature communications 15 (1) (2024)
Jace Jones-Tabah, Kathy He, Konstantin Senkevich, Nathan Karpilovsky, Ghislaine Deyab, Yuting Cousineau, Daria Nikanorova, Taylor Goldsmith, Esther Del-Cid Pellitero, Carol Xq Chen, Wen Luo, Zhipeng You, Narges Abdian, Isabella Pietrantonio, Thomas Goiran, Jamil Ahmad, Jennifer A Ruskey, Farnaz Asayesh, Dan Spiegelman, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupre, Irina Miliukhina, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Lior Greenbaum, Sharon HassinBaer, Roy N Alcalay, Austen Milnerwood, Thomas M Durcan, Ziv Gan-Or, Edward A Fon
The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons. Research square (2024)
Mohamed A Eldeeb, Andrew N Bayne, Armaan Fallahi, Thomas Goiran, Emma J MacDougall, Andrea Soumbasis, Cornelia E Zorca, Jace-Jones Tabah, Rhalena A Thomas, Nathan Karpilovsky, Meghna Mathur, Thomas M Durcan, Jean-François Trempe, Edward A Fon
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress. Proceedings of the National Academy of Sciences of the United States of America 121 (10) (2024)
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul M K Muqit, Jean-François Trempe
Structure-based design and characterization of Parkin-activating mutations. Life science alliance 6 (6) (2023)
Alex I Wiesman, Jason da Silva Castanheira, Edward A Fon, Sylvain Baillet, null null, null null
Structural and neurophysiological alterations in Parkinson's disease are aligned with cortical neurochemical systems. medRxiv : the preprint server for health sciences (2023)
Alex I Wiesman, Peter W Donhauser, Clotilde Degroot, Sabrina Diab, Shanna Kousaie, Edward A Fon, Denise Klein, Sylvain Baillet, null null, null null
Aberrant neurophysiological signaling associated with speech impairments in Parkinson's disease. NPJ Parkinson's disease 9 (1) (2023)
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul M K Muqit, Jean-François Trempe
Structure-based design and characterization of Parkin-activating mutations. Life science alliance 6 (6) (2023)
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul M K Muqit, Jean-François Trempe
Structure-based design and characterization of Parkin-activating mutations. Life science alliance 6 (6) (2023)
Marie-France Dorion, Moein Yaqubi, Konstantin Senkevich, Nicholas W Kieran, Adam MacDonald, Carol X-Q Chen, Wen Luo, Amber Wallis, Irina Shlaifer, Jeffery A Hall, Roy W R Dudley, Ian A Glass, null null, Jo Anne Stratton, Edward A Fon, Tim Bartels, Jack P Antel, Ziv Gan Or, Thomas M Durcan, Luke M Healy
MerTK is a mediator of alpha-synuclein fibril uptake by human microglia. Brain : a journal of neurology (2023)
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul M K Muqit, Jean-François Trempe
Structure-based design and characterization of Parkin-activating mutations. Life science alliance 6 (6) (2023)
Eric Yu, Roxanne Larivière, Rhalena A Thomas, Lang Liu, Konstantin Senkevich, Shady Rahayel, Jean-François Trempe, Edward A Fon, Ziv Gan Or
Machine learning nominates the inositol pathway and novel genes in Parkinson's disease. Brain : a journal of neurology (2023)
Mohamed A Eldeeb, Rhalena A Thomas, Mohamed A Ragheb, Armaan Fallahi, Edward A Fon
Mitochondrial quality control in health and in Parkinson's disease. Physiological reviews 102 (4) (2022)
Marta Vranas, Yang Lu, Shafqat Rasool, Nathalie Croteau, Jonathan D Krett, Véronique Sauvé, Kalle Gehring, Edward A Fon, Thomas Martin Durcan, Jean-François Trempe
Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria. Open biology 12 (1) (2022)
Konstantin Senkevich, Cornelia E Zorca, Aliza Dworkind, Uladzislau Rudakou, Emma Somerville, Eric Yu, Alexey Ermolaev, Daria Nikanorova, Jamil Ahmad, Jennifer A Ruskey, Farnaz Asayesh, Dan Spiegelman, Stanley Fahn, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupré, Lior Greenbaum, Sharon Hassin-Baer, Francis P Grenn, Ming Sum Ruby Chiang, S Pablo Sardi, Benoît Vanderperre, Cornelis Blauwendraat, Jean-François Trempe, Edward A Fon, Thomas M Durcan, Roy N Alcalay, Ziv Gan Or
GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson's disease. Brain : a journal of neurology (2022)
Morgan Bérard, Razan Sheta, Sarah Malvaut, Raquel Rodriguez-Aller, Maxime Teixeira, Walid Idi, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Manel Dahmene, Charleen Salesse, Jérôme Lamontagne-Proulx, Marie-Kim St-Pierre, Omid Tavassoly, Wen Luo, Esther Del Cid-Pellitero, Raza Qazi, Jae-Woong Jeong, Thomas Martin Durcan, Luc Vallières, Marie-Eve Tremblay, Denis Soulet, Martin Lévesque, Francesca Cicchetti, Edward A Fon, Armen Saghatelyan, Abid Oueslati
A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease. PLoS biology 20 (3) (2022)
Véronique Sauvé, George Sung, Emma J MacDougall, Guennadi Kozlov, Anshu Saran, Rayan Fakih, Edward A Fon, Kalle Gehring
Structural basis for feedforward control in the PINK1/Parkin pathway. The EMBO journal 41 (12) (2022)
Thomas Goiran, Mohamed A Eldeeb, Cornelia E Zorca, Edward A Fon
Hallmarks and Molecular Tools for the Study of Mitophagy in Parkinson's Disease. Cells 11 (13) (2022)
Nguyen-Vi Mohamed, Julien Sirois, Janani Ramamurthy, Meghna Mathur, Paula Lépine, Eric Deneault, Gilles Maussion, Michael Nicouleau, Carol X-Q Chen, Narges Abdian, Vincent Soubannier, Eddie Cai, Harris Nami, Rhalena A Thomas, Dingke Wen, Mahdieh Tabatabaei, Lenore K Beitel, Karamjit Singh Dolt, Jason Karamchandani, Jo Anne Stratton, Tilo Kunath, Edward A Fon, Thomas M Durcan
Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy. Brain communications 3 (4) (2021)
Jack Wuyang Jin, Xuelai Fan, Esther Del Cid-Pellitero, Xing-Xing Liu, Limin Zhou, Chunfang Dai, Ebrima Gibbs, Wenting He, Hongjie Li, Xiaobin Wu, Austin Hill, Blair R Leavitt, Neil R Cashman, Lidong Liu, Jie Lu, Thomas M Durcan, Zhifang Dong, Edward A Fon, Yu Tian Wang
Development of an α-synuclein knockdown peptide and evaluation of its efficacy in Parkinson's disease models. Communications biology 4 (1) (2021)
Rosalind F Roberts, Andrew N Bayne, Thomas Goiran, Dominique Lévesque, François-Michel Boisvert, Jean-François Trempe, Edward A Fon
Proteomic Profiling of Mitochondrial-Derived Vesicles in Brain Reveals Enrichment of Respiratory Complex Sub-assemblies and Small TIM Chaperones. Journal of proteome research 20 (1) (2020)
Uladzislau Rudakou, Jennifer A Ruskey, Lynne Krohn, Sandra B Laurent, Dan Spiegelman, Lior Greenbaum, Gilad Yahalom, Alex Desautels, Jacques Y Montplaisir, Stanley Fahn, Cheryl H Waters, Oren Levy, Caitlin M Kehoe, Sushma Narayan, Yves Dauvilliers, Nicolas Dupre, Sharon Hassin-Baer, Roy N Alcalay, Guy A Rouleau, Edward A Fon, Ziv Gan Or
Analysis of common and rare VPS13C variants in late-onset Parkinson disease. Neurology. Genetics 6 (1) (2020)
Julie Pilliod, Alexandre Desjardins, Camille Pernègre, Hélène Jamann, Catherine Larochelle, Edward A Fon, Nicole Leclerc
Clearance of intracellular tau protein from neuronal cells via VAMP8-induced secretion. The Journal of biological chemistry (2020)
Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Nadine D Lauinger, Andrea I Krahn, Sepideh Valimehr, Aleksandar Rakovic, Isabelle Rouiller, Thomas M Durcan, Jean-François Trempe, Edward A Fon
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. eLife 7 (2018)
Gian-Luca McLelland, Edward A Fon
MFN2 retrotranslocation boosts mitophagy by uncoupling mitochondria from the ER. Autophagy 14 (9) (2018)
Gian-Luca McLelland, Sydney A Lee, Heidi M McBride, Edward A Fon
Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. The Journal of cell biology 214 (3) (2016)

Edward A Fon.css-eqlu8i{font-size:small;padding-left:4px;} (Edward Fon)

Publication Activity (10 Years)

Top Topics

Top Venues

Edward A Fon (Edward Fon)