Jeffrey N Savas (Jeffrey Savas)

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 33

Top Topics

Intellectual Disability

Prefrontal Cortex

Acute Lymphoblastic Leukemia

Top Venues

Nature communications

Molecular psychiatry

Molecular systems biology

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Yi-Zhi Wang, Tamara Perez-Rosello, Samuel N Smukowski, Dalton James Surmeier, Jeffrey N Savas
Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iSPNs and dSPNs lead to striatal synaptopathy in Shank3B -/- mice. Molecular psychiatry (2024)
Yi-Zhi Wang, Tamara Perez-Rosello, Samuel N Smukowski, Dalton James Surmeier, Jeffrey N Savas
Correction: Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iSPNs and dSPNs lead to striatal synaptopathy in Shank3B -/- mice. Molecular psychiatry (2024)
Nalini R Rao, Arun Upadhyay, Jeffrey N Savas
Derailed protein turnover in the aging mammalian brain. Molecular systems biology 20 (2) (2024)
Yi-Zhi Wang, Tamara Perez-Rosello, Samuel N Smukowski, Dalton James Surmeier, Jeffrey N Savas
Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iSPNs and dSPNs lead to striatal synaptopathy in Shank3B -/- mice. Molecular psychiatry (2024)
Nalini R Rao, Arun Upadhyay, Jeffrey N Savas
Derailed protein turnover in the aging mammalian brain. Molecular systems biology 20 (2) (2024)
Nalini R Rao, Arun Upadhyay, Jeffrey N Savas
Derailed protein turnover in the aging mammalian brain. Molecular systems biology 20 (2) (2024)
Nalini R Rao, Arun Upadhyay, Jeffrey N Savas
Derailed protein turnover in the aging mammalian brain. Molecular systems biology (2024)
Nalini R Rao, Arun Upadhyay, Jeffrey N Savas
Derailed protein turnover in the aging mammalian brain. Molecular systems biology 20 (2) (2024)
Yi-Zhi Wang, Tamara Perez-Rosello, Samuel N Smukowski, Dalton James Surmeier, Jeffrey N Savas
Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iPSNs and dSPNs lead to striatal synaptopathy in Shank3B -/- mice. Molecular psychiatry (2024)
Yi-Zhi Wang, Tamara Perez-Rosello, Samuel N Smukowski, Dalton James Surmeier, Jeffrey N Savas
Correction: Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iSPNs and dSPNs lead to striatal synaptopathy in Shank3B -/- mice. Molecular psychiatry (2024)
Ewa K Bomba-Warczak, Karen M Velez, Luhan T Zhou, Christelle Guillermier, Seby Edassery, Matthew Steinhauser, Jeffrey N Savas, Francesca E Duncan
Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan. bioRxiv : the preprint server for biology (2023)
Marc P Forrest, Marc Dos Santos, Nicolas H Piguel, Yi-Zhi Wang, Nicole A Hawkins, Vikram A Bagchi, Leonardo E Dionisio, Sehyoun Yoon, Dina Simkin, María Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E Horan, Alfred L George, Mark S LeDoux, Jennifer A Kearney, Jeffrey N Savas, Peter Penzes
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. Nature communications 14 (1) (2023)
Marc P Forrest, Marc Dos Santos, Nicolas H Piguel, Yi-Zhi Wang, Nicole A Hawkins, Vikram A Bagchi, Leonardo E Dionisio, Sehyoun Yoon, Dina Simkin, María Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E Horan, Alfred L George, Mark S LeDoux, Jennifer A Kearney, Jeffrey N Savas, Peter Penzes
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. Nature communications 14 (1) (2023)
Marc P Forrest, Marc Dos Santos, Nicolas H Piguel, Yi-Zhi Wang, Nicole A Hawkins, Vikram A Bagchi, Leonardo E Dionisio, Sehyoun Yoon, Dina Simkin, María Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E Horan, Alfred L George, Mark S LeDoux, Jennifer A Kearney, Jeffrey N Savas, Peter Penzes
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. Nature communications 14 (1) (2023)
Marc P Forrest, Marc Dos Santos, Nicolas H Piguel, Yi-Zhi Wang, Nicole A Hawkins, Vikram A Bagchi, Leonardo E Dionisio, Sehyoun Yoon, Dina Simkin, María Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E Horan, Alfred L George, Mark S LeDoux, Jennifer A Kearney, Jeffrey N Savas, Peter Penzes
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. Nature communications 14 (1) (2023)
Marc P Forrest, Marc Dos Santos, Nicolas H Piguel, Yi-Zhi Wang, Nicole A Hawkins, Vikram A Bagchi, Leonardo E Dionisio, Sehyoun Yoon, Dina Simkin, María Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E Horan, Alfred L George, Mark S LeDoux, Jennifer A Kearney, Jeffrey N Savas, Peter Penzes
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. Nature communications 14 (1) (2023)
Marc P Forrest, Marc Dos Santos, Nicolas H Piguel, Yi-Zhi Wang, Nicole A Hawkins, Vikram A Bagchi, Leonardo E Dionisio, Sehyoun Yoon, Dina Simkin, María Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E Horan, Alfred L George, Mark S LeDoux, Jennifer A Kearney, Jeffrey N Savas, Peter Penzes
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub. Nature communications 14 (1) (2023)
Arun Upadhyay, Deepak Chhangani, Nalini R Rao, Julia Kofler, Robert Vassar, Diego E Rincon-Limas, Jeffrey N Savas
Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity. Molecular neurodegeneration 18 (1) (2023)
Roger S Smith, Seesha R Takagishi, David R Amici, Kyle A Metz, Sitaram Gayatri, Milad J Alasady, Yaqi Wu, Sonia Brockway, Stephanie L Taiberg, Natalia Khalatyan, Mikko Taipale, Sandro Santagata, Luke Whitesell, Susan Lindquist, Jeffrey N Savas, Marc L Mendillo
HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state. Science advances 8 (11) (2022)
Caitlin E Pegg, Sofia V Zaichick, Ewa Bomba-Warczak, Vladimir Jovasevic, DongHo Kim, Himanshu Kharkwal, Duncan W Wilson, Derek Walsh, Patricia J Sollars, Gary E Pickard, Jeffrey N Savas, Gregory A Smith
Herpesviruses assimilate kinesin to produce motorized viral particles. Nature 599 (7886) (2021)
Timothy J Hark, Jeffrey N Savas
Using stable isotope labeling to advance our understanding of Alzheimer's disease etiology and pathology. Journal of neurochemistry 159 (2) (2021)
Kaitlyn M McGrath, Shivani Agarwal, Marco Tonelli, Mykola Dergai, Anthony L Gaeta, Andrew K Shum, Jessica Lacoste, Yongbo Zhang, Wen-Yu Wen, Daayun Chung, Grant Wiersum, Aishwarya Shevade, Sofia Zaichick, Damian B van Rossum, Ludmilla Shuvalova, Jeffrey N Savas, Sergei Kuchin, Mikko Taipale, Kim A Caldwell, Guy A Caldwell, Dirk Fasshauer, Gabriela Caraveo
A conformational switch driven by phosphorylation regulates the activity of the evolutionarily conserved SNARE Ykt6. Proceedings of the National Academy of Sciences of the United States of America 118 (12) (2021)
Ewa K Bomba-Warczak, Seby L Edassery, Timothy J Hark, Jeffrey N Savas
Long-lived mitochondrial cristae proteins in mouse heart and brain. The Journal of cell biology 220 (9) (2021)
Sehyoun Yoon, Nicolas H Piguel, Natalia Khalatyan, Leonardo E Dionisio, Jeffrey N Savas, Peter Penzes
Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome. Molecular psychiatry 26 (6) (2021)
Laurie P Sutton, Natalia Khalatyan, Jeffrey N Savas, Kirill A Martemyanov
Striatal RGS7 Regulates Depression-Related Behaviors and Stress-Induced Reinstatement of Cocaine Conditioned Place Preference. eNeuro 8 (2) (2021)
Shashank Srivastava, Umakant Sahu, Yalu Zhou, Ann K Hogan, Kizhakke Mattada Sathyan, Justin Bodner, Jiehuan Huang, Kelvin A Wong, Natalia Khalatyan, Jeffrey N Savas, Panagiotis Ntziachristos, Issam Ben-Sahra, Daniel R Foltz
NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia. Science advances 7 (5) (2021)
Nuno Apóstolo, Samuel N Smukowski, Jeroen Vanderlinden, Giuseppe Condomitti, Vasily Rybakin, Jolijn Ten Bos, Laura Trobiani, Sybren Portegies, Kristel M Vennekens, Natalia V Gounko, Davide Comoletti, Keimpe D Wierda, Jeffrey N Savas, Joris de Wit
Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer. Nature communications 11 (1) (2020)
Zibo Zhao, Lu Wang, Elizabeth Thomas Bartom, Stacy A Marshall, Emily Jane Rendleman, Caila Ryan, Anthony Shilati, Jeffrey N Savas, Navdeep S Chandel, Ali Shilatifard
β-Catenin/Tcf7l2-dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer. Science advances 5 (7) (2019)
Andrea Piunti, Edwin R Smith, Marc Alard Jonathan Morgan, Michal Ugarenko, Natalia Khaltyan, Kathryn A Helmin, Caila A Ryan, David C Murray, Ryan A Rickels, Bahar D Yilmaz, Emily Jane Rendleman, Jeffrey N Savas, Benjamin David Singer, Serdar E Bulun, Ali Shilatifard
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism. Science advances 5 (7) (2019)
Pan Liu, Seby Louis Edassery, Laith Ali, Benjamin R Thomson, Jeffrey N Savas, Jing Jin
Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry. eLife 8 (2019)
Yi-Zhi Wang, Jeffrey N Savas
Uncovering Discrete Synaptic Proteomes to Understand Neurological Disorders. Proteomes 6 (3) (2018)
Joonhee Park, Jingyi Yang, Alexander T Wenzel, Akshaya Ramachandran, Wung J Lee, Jay C Daniels, Juhyun Kim, Maria Estela Martinez Escala, Nduka Amankulor, Barbara Pro, Joan Guitart, Marc L Mendillo, Jeffrey N Savas, Titus J Boggon, Jaehyuk Choi
Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood 130 (12) (2017)
Ann E Hickox, Ann C Y Wong, Kwang Pak, Chelsee Strojny, Miguel Ramirez, John Yates Iii, Allen F Ryan, Jeffrey N Savas
Global Analysis of Protein Expression of Inner Ear Hair Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (5) (2016)
Natalie F Shanks, Ondrej Cais, Tomohiko Maruo, Jeffrey N Savas, Elena I Zaika, Caleigh M Azumaya, John R Yates, Ingo Greger, Terunaga Nakagawa
Molecular dissection of the interaction between the AMPA receptor and cornichon homolog-3. The Journal of neuroscience : the official journal of the Society for Neuroscience 34 (36) (2014)