Ali Shilatifard

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 57

Top Topics

Embryonic Stem Cells

Gene Expression

Pulmonary Fibrosis

Top Venues

Science advances

Science (New York, N.Y.)

Nature genetics

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Umakant Sahu, Elodie Villa, Colleen R Reczek, Zibo Zhao, Brendan P O'Hara, Michael D Torno, Rohan Mishra, William D Shannon, John M Asara, Peng Gao, Ali Shilatifard, Navdeep S Chandel, Issam Ben-Sahra
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis. Science (New York, N.Y.) 383 (6690) (2024)
Umakant Sahu, Elodie Villa, Colleen R Reczek, Zibo Zhao, Brendan P O'Hara, Michael D Torno, Rohan Mishra, William D Shannon, John M Asara, Peng Gao, Ali Shilatifard, Navdeep S Chandel, Issam Ben-Sahra
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis. Science (New York, N.Y.) 383 (6690) (2024)
Umakant Sahu, Elodie Villa, Colleen R Reczek, Zibo Zhao, Brendan P O'Hara, Michael D Torno, Rohan Mishra, William D Shannon, John M Asara, Peng Gao, Ali Shilatifard, Navdeep S Chandel, Issam Ben-Sahra
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis. Science (New York, N.Y.) 383 (6690) (2024)
Umakant Sahu, Elodie Villa, Colleen R Reczek, Zibo Zhao, Brendan P O'Hara, Michael D Torno, Rohan Mishra, William D Shannon, John M Asara, Peng Gao, Ali Shilatifard, Navdeep S Chandel, Issam Ben-Sahra
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis. Science (New York, N.Y.) 383 (6690) (2024)
Umakant Sahu, Elodie Villa, Colleen R Reczek, Zibo Zhao, Brendan P O'Hara, Michael D Torno, Rohan Mishra, William D Shannon, John M Asara, Peng Gao, Ali Shilatifard, Navdeep S Chandel, Issam Ben-Sahra
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis. Science (New York, N.Y.) 383 (6690) (2024)
Shimaa H A Soliman, William J Cisneros, Marta Iwanaszko, Yuki Aoi, Sheetal Ganesan, Miriam Walter, Jacob M Zeidner, Rama K Mishra, Eun-Young Kim, Steven M Wolinsky, Judd F Hultquist, Ali Shilatifard
Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C. Science advances 9 (10) (2023)
Marc Alard Jonathan Morgan, Ali Shilatifard
Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription. Science advances 9 (16) (2023)
Marc Alard Jonathan Morgan, Ali Shilatifard
Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription. Science advances 9 (16) (2023)
Jason S Shapiro, Hsiang-Chun Chang, Yuki Tatekoshi, Zibo Zhao, Zohra Sattar Waxali, Bong Jin Hong, Haimei Chen, Justin A Geier, Elizabeth Thomas Bartom, Adam De Jesus, Farnaz K Nejad, Amir Mahmoodzadeh, Tatsuya Sato, Lucia Ramos-Alonso, Antonia Maria Romero, Maria Teresa Martinez-Pastor, Shang-Chuan Jiang, Shiv K Sah-Teli, Liming Li, David Bentrem, Gary Lopaschuk, Issam Ben-Sahra, Thomas V O'Halloran, Ali Shilatifard, Sergi Puig, Joy Bergelson, Peppi Koivunen, Hossein Ardehali
Iron drives anabolic metabolism through active histone demethylation and mTORC1. Nature cell biology (2023)
Ali Shilatifard
For the love of Science…Advances. Science advances 9 (50) (2023)
Marc Alard Jonathan Morgan, Saeid Mohammad Parast, Marta Iwanaszko, Yuki Aoi, DongAhn Yoo, Zachary J Dumar, Benjamin C Howard, Kathryn A Helmin, Qianli Liu, William R Thakur, Jacob M Zeidner, Benjamin David Singer, Evan E Eichler, Ali Shilatifard
ELOA3 : A primate-specific RNA polymerase II elongation factor encoded by a tandem repeat gene cluster. Science advances 9 (47) (2023)
Marc Alard Jonathan Morgan, Ali Shilatifard
Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription. Science advances 9 (16) (2023)
Shimaa H A Soliman, William J Cisneros, Marta Iwanaszko, Yuki Aoi, Sheetal Ganesan, Miriam Walter, Jacob M Zeidner, Rama K Mishra, Eun-Young Kim, Steven M Wolinsky, Judd F Hultquist, Ali Shilatifard
Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C. Science advances 9 (10) (2023)
Nozomu Takata, Jason M Miska, Marc Alard Jonathan Morgan, Priyam A Patel, Leah K Billingham, Neha Joshi, Matthew J Schipma, Zachary J Dumar, Nikita R Joshi, Alexander V Misharin, Ryan B Embry, Luciano Fiore, Peng Gao, Lauren P Diebold, Gregory S McElroy, Ali Shilatifard, Navdeep S Chandel, Guillermo Oliver
Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis. Nature communications 14 (1) (2023)
Marc Alard Jonathan Morgan, Ali Shilatifard
Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription. Science advances 9 (16) (2023)
Marc Alard Jonathan Morgan, Ali Shilatifard
Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription. Science advances 9 (16) (2023)
Ali Shilatifard
The power of altruism in academic science. Science advances 9 (27) (2023)
Shimaa H A Soliman, William J Cisneros, Marta Iwanaszko, Yuki Aoi, Sheetal Ganesan, Miriam Walter, Jacob M Zeidner, Rama K Mishra, Eun-Young Kim, Steven M Wolinsky, Judd F Hultquist, Ali Shilatifard
Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C. Science advances 9 (10) (2023)
Marc Alard Jonathan Morgan, Ali Shilatifard
Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription. Science advances 9 (16) (2023)
Marc Alard Jonathan Morgan, Ali Shilatifard
Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription. Science advances 9 (16) (2023)
Shimaa H A Soliman, William J Cisneros, Marta Iwanaszko, Yuki Aoi, Sheetal Ganesan, Miriam Walter, Jacob M Zeidner, Rama K Mishra, Eun-Young Kim, Steven M Wolinsky, Judd F Hultquist, Ali Shilatifard
Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C. Science advances 9 (10) (2023)
Ali Shilatifard
The dire need for federal support of molecular research, then and now. Science advances 8 (23) (2022)
Zibo Zhao, Emily Jane Rendleman, Aileen Patricia Szczepanski, Marc Alard Jonathan Morgan, Lu Wang, Ali Shilatifard
CARM1-mediated methylation of ASXL2 impairs tumor-suppressive function of MLL3/COMPASS. Science advances 8 (40) (2022)
Ali Shilatifard
On Healthy Scientific Debates. Science advances 8 (13) (2022)
Andrea Piunti, Khyati Meghani, Yanni Yu, A Gordon Robertson, Joseph R Podojil, Kimberly A McLaughlin, Zonghao You, Damiano Fantini, MingYi Chiang, Yi Luo, Lu Wang, Nathan Heyen, Jun Qian, Stephen D Miller, Ali Shilatifard, Joshua J Meeks
Immune activation is essential for the antitumor activity of EZH2 inhibition in urothelial carcinoma. Science advances 8 (40) (2022)
Ali Shilatifard
Expanding the breadth and depth of Science Advances. Science advances 7 (34) (2021)
Gloria Pascual, Diana Domínguez, Antoni Berenguer Llergo, Felipe Cesar Beckedorff, Camille Stephan-Otto Attolini, Claudia Bigas, Delphine Douillet, Carolina Greco, Aikaterini Symeonidi, Inmaculada Hernández, Sara Ruiz Gil, Neus Prats, Coro Bescós, Ramin Shiekhattar, Moran Amit, Holger Heyn, Ali Shilatifard, Salvador Aznar Benitah
Dietary palmitic acid promotes a prometastatic memory via Schwann cells. Nature 599 (7885) (2021)
Lu Wang, Noah Warren Birch, Zibo Zhao, Carson Meredith Nestler, Alexander Kazmer, Anthony Shilati, Alisha Blake, Patrick Alexander Ozark, Emily Jane Rendleman, Didi Zha, Caila Ann Ryan, Marc Alard Jonathan Morgan, Ali Shilatifard
Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia. Nature cancer 2 (5) (2021)
Rogan A Grant, Luisa Morales-Nebreda, Nikolay S Markov, Suchitra Swaminathan, Melissa Querrey, Estefany R Guzman, Darryl A Abbott, Helen K Donnelly, Alvaro Donayre, Isaac A Goldberg, Zasu M Klug, Nicole Borkowski, Ziyan Lu, Hermon Kihshen, Yuliya Politanska, Lango Sichizya, Mengjia Kang, Ali Shilatifard, Chao Qi, Jon W Lomasney, A Christine Argento, Jacqueline M Kruser, Elizabeth S Malsin, Chiagozie O Pickens, Sean B Smith, James M Walter, Anna E Pawlowski, Daniel Schneider, Prasanth Nannapaneni, Hiam Abdala-Valencia, Ankit Bharat, Cara J Gottardi, G R Scott Budinger, Alexander V Misharin, Benjamin David Singer, Richard G Wunderink, null null
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia. Nature 590 (7847) (2021)
Luis F Schachner, Kevin Jooß, Marc Alard Jonathan Morgan, Andrea Piunti, Matthew J Meiners, Jared O Kafader, Alexander S Lee, Marta Iwanaszko, Marcus A Cheek, Jonathan M Burg, Sarah A Howard, Michael-Christopher Keogh, Ali Shilatifard, Michael P Snyder
Decoding the protein composition of whole nucleosomes with Nuc-MS. Nature methods 18 (3) (2021)
Ali Shilatifard
Building on a strong foundation. Science advances 7 (17) (2021)
Andrea Piunti, Ali Shilatifard
The roles of Polycomb repressive complexes in mammalian development and cancer. Nature reviews. Molecular cell biology 22 (5) (2021)
Juan Wang, Tina Yi-Ting Huang, Ye Hou, Elizabeth Thomas Bartom, Xinyan Lu, Ali Shilatifard, Feng Yue, Amanda Muhs Saratsis
Epigenomic landscape and 3D genome structure in pediatric high-grade glioma. Science advances 7 (23) (2021)
Lucas Ferreira Dasilva, Ezra Blumenthal, Felipe Cesar Beckedorff, Pradeep Reddy Cingaram, Helena Gomes Dos Santos, Raghu Ram Edupuganti, Anda Zhang, Sadat Dokaneheifard, Yuki Aoi, Jingyin Yue, Nina Kirstein, Mina Masoumeh Tayari, Ali Shilatifard, Ramin Shiekhattar
Integrator enforces the fidelity of transcriptional termination at protein-coding genes. Science advances 7 (45) (2021)
Ankit Bharat, Melissa Querrey, Nikolay S Markov, Samuel S Kim, Chitaru Kurihara, Rafael Garza-Castillon, Adwaiy Manerikar, Ali Shilatifard, Rade Tomic, Yuliya Politanska, Hiam Abdala-Valencia, Anjana V Yeldandi, Jon W Lomasney, Alexander V Misharin, G R Scott Budinger
Lung transplantation for patients with severe COVID-19. Science translational medicine 12 (574) (2020)
Bercin K Cenik, Ali Shilatifard
COMPASS and SWI/SNF complexes in development and disease. Nature reviews. Genetics 22 (1) (2020)
Ali Shilatifard
COVID-19: Rescue by transcriptional inhibition. Science advances 6 (27) (2020)
Delphine Douillet, Christie C Sze, Caila Ryan, Andrea Piunti, Avani P Shah, Michal Ugarenko, Stacy A Marshall, Emily J Rendleman, Didi Zha, Kathryn A Helmin, Zibo Zhao, Kaixiang Cao, Marc A Morgan, Benjamin David Singer, Elizabeth Thomas Bartom, Edwin R Smith, Ali Shilatifard
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation. Nature genetics 52 (6) (2020)
Marc Alard Jonathan Morgan, Ali Shilatifard
Reevaluating the roles of histone-modifying enzymes and their associated chromatin modifications in transcriptional regulation. Nature genetics 52 (12) (2020)
Christie C Sze, Patrick Alexander Ozark, Kaixiang Cao, Michal Ugarenko, Siddhartha Das, Lu Wang, Stacy A Marshall, Emily Jane Rendleman, Caila A Ryan, Didi Zha, Delphine Douillet, Fei Xavier Chen, Ali Shilatifard
Coordinated regulation of cellular identity-associated H3K4me3 breadth by the COMPASS family. Science advances 6 (26) (2020)
Ankit Bharat, Melissa Querrey, Nikolay S Markov, Samuel S Kim, Chitaru Kurihara, Rafael Garza-Castillon, Adwaiy Manerikar, Ali Shilatifard, Rade Tomic, Yuliya Politanska, Hiam Abdala-Valencia, Anjana V Yeldandi, Jon W Lomasney, Alexander V Misharin, G R Scott Budinger
Lung transplantation for pulmonary fibrosis secondary to severe COVID-19. medRxiv : the preprint server for health sciences (2020)
Rogan A Grant, Luisa Morales-Nebreda, Nikolay S Markov, Suchitra Swaminathan, Estefany R Guzman, Darryl A Abbott, Helen K Donnelly, Alvaro Donayre, Isaac A Goldberg, Zasu M Klug, Nicole Borkowski, Ziyan Lu, Hermon Kihshen, Yuliya Politanska, Lango Sichizya, Mengjia Kang, Ali Shilatifard, Chao Qi, A Christine Argento, Jacqueline M Kruser, Elizabeth S Malsin, Chiagozie O Pickens, Sean B Smith, James M Walter, Anna E Pawlowski, Daniel Schneider, Prasanth Nannapaneni, Hiam Abdala-Valencia, Ankit Bharat, Cara J Gottardi, G R Scott Budinger, Alexander V Misharin, Benjamin David Singer, Richard G Wunderink, null null
Alveolitis in severe SARS-CoV-2 pneumonia is driven by self-sustaining circuits between infected alveolar macrophages and T cells. bioRxiv : the preprint server for biology (2020)
Ali Shilatifard
Medicine in the time of corona: Fundamental molecular research is "essential". Science advances 6 (23) (2020)
Zibo Zhao, Lu Wang, Elizabeth Thomas Bartom, Stacy A Marshall, Emily Jane Rendleman, Caila Ryan, Anthony Shilati, Jeffrey N Savas, Navdeep S Chandel, Ali Shilatifard
β-Catenin/Tcf7l2-dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer. Science advances 5 (7) (2019)
Kevin J Frankowski, Chen Wang, Samarjit Patnaik, Frank J Schoenen, Noel T Southall, Dandan Li, Yaroslav Teper, Wei Sun, Irawati Kandela, Deqing Hu, Christopher Dextras, Zachary Knotts, Yansong Bian, John Norton, Steve Titus, Marzena A Lewandowska, Yiping Wen, Katherine I Farley, Lesley Mathews Griner, Jamey Sultan, Zhaojing Meng, Ming Zhou, Tomas Vilimas, Astin S Powers, Serguei Kozlov, Kunio Nagashima, Humair S Quadri, Min Fang, Charles Long, Ojus Khanolkar, Warren Chen, Jinsol Kang, Helen Huang, Eric Chow, Esthermanya Goldberg, Coral Feldman, Romi Xi, Hye Rim Kim, Gary Sahagian, Susan J Baserga, Andrew Mazar, Marc Ferrer, Wei Zheng, Ali Shilatifard, Jeffrey Aube, Rushikesh Sable, Juan Jose Marugan, Sui Huang
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Science translational medicine 10 (441) (2019)
Joshua Pan, Zachary M McKenzie, Andrew R D'Avino, Nazar Mashtalir, Caleb A Lareau, Roodolph St Pierre, Lu Wang, Ali Shilatifard, Cigall Kadoch
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting. Nature genetics 51 (4) (2019)
Andrea Piunti, Edwin R Smith, Marc Alard Jonathan Morgan, Michal Ugarenko, Natalia Khaltyan, Kathryn A Helmin, Caila A Ryan, David C Murray, Ryan A Rickels, Bahar D Yilmaz, Emily Jane Rendleman, Jeffrey N Savas, Benjamin David Singer, Serdar E Bulun, Ali Shilatifard
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism. Science advances 5 (7) (2019)
Gary LeRoy, Ozgur Oksuz, Nicolas Descostes, Yuki Aoi, Rais A Ganai, Havva Ortabozkoyun Kara, Jia-Ray Yu, Chul-Hwan Lee, James Stafford, Ali Shilatifard, Danny Reinberg
LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells. Science advances 5 (10) (2019)
Chia-Yu Chung, Amit Berson, Jason R Kennerdell, Ashley Sartoris, Travis Unger, Sílvia Porta, Hyung-Jun Kim, Edwin R Smith, Ali Shilatifard, Vivianna Van Deerlin, Virginia M-Y Lee, Alice Chen-Plotkin, Nancy M Bonini
Author Correction: Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature communications 10 (1) (2019)
Chia-Yu Chung, Amit Berson, Jason R Kennerdell, Ashley Sartoris, Travis Unger, Sílvia Porta, Hyung-Jun Kim, Edwin R Smith, Ali Shilatifard, Vivianna Van Deerlin, Virginia M-Y Lee, Alice Chen-Plotkin, Nancy M Bonini
Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature communications 9 (1) (2018)
Ali Shilatifard
Impactful science as the guiding principle. Science advances 4 (7) (2018)
Lu Wang, Patrick Alexander Ozark, Edwin R Smith, Zibo Zhao, Stacy A Marshall, Emily Jane Rendleman, Andrea Piunti, Caila Ryan, Anna L Whelan, Kathryn A Helmin, Marc Alard Jonathan Morgan, Lihua Zou, Benjamin David Singer, Ali Shilatifard
TET2 coactivates gene expression through demethylation of enhancers. Science advances 4 (11) (2018)
Gloria Mas Martin, Enrique Blanco, Cecilia Ballaré, Miriam Sansó, Yannick G Spill, Deqing Hu, Yuki Aoi, François Le Dily, Ali Shilatifard, Marc A Marti-Renom, Luciano Di Croce
Promoter bivalency favors an open chromatin architecture in embryonic stem cells. Nature genetics 50 (10) (2018)
Lu Wang, Zibo Zhao, Patrick A Ozark, Damiano Fantini, Stacy A Marshall, Emily J Rendleman, Kira A Cozzolino, Nundia Louis, Xingyao He, Marc A Morgan, Yoh-Hei Takahashi, Clayton K Collings, Edwin R Smith, Panagiotis Ntziachristos, Jeffrey N Savas, Lihua Zou, Rintaro Hashizume, Joshua J Meeks, Ali Shilatifard
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy. Nature medicine 24 (6) (2018)
Kaixiang Cao, Clayton K Collings, Marc Alard Jonathan Morgan, Stacy A Marshall, Emily Jane Rendleman, Patrick Alexander Ozark, Edwin R Smith, Ali Shilatifard
An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells. Science advances 4 (1) (2018)
Fei Xavier Chen, Peng Xie, Clayton K Collings, Kaixiang Cao, Yuki Aoi, Stacy A Marshall, Emily Jane Rendleman, Michal Ugarenko, Patrick Alexander Ozark, Anda Zhang, Ramin Shiekhattar, Edwin R Smith, Michael Q Zhang, Ali Shilatifard
PAF1 regulation of promoter-proximal pause release via enhancer activation. Science (New York, N.Y.) 357 (6357) (2017)
Ryan Rickels, Hans-Martin Herz, Christie C Sze, Kaixiang Cao, Marc A Morgan, Clayton K Collings, Maria Gause, Yoh-Hei Takahashi, Lu Wang, Emily J Rendleman, Stacy A Marshall, Annika Krueger, Elizabeth T Bartom, Andrea Piunti, Edwin R Smith, Nebiyu A Abshiru, Neil L Kelleher, Dale Dorsett, Ali Shilatifard
Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability. Nature genetics 49 (11) (2017)