Jens Hjerling Leffler (Jens Hjerling-Leffler)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 30

Top Topics

Genome Wide Association

Dna Methylation

Major Depressive Disorder

Top Venues

Nature cardiovascular research

Nature genetics

Nature neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Jacob Bergstedt, Joëlle A Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L Treur, Dirk J A Smit, Oleksandr Frei, Alexey A Shadrin, Joeri J Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas M Werge, Jens Hjerling Leffler, Thomas Damm Als, Anders Dupont Børglum, Cathryn M Lewis, Andrew M McIntosh, Unnur Anna Valdimarsdottir, Ole Andreas Andreassen, Patrick F Sullivan, Yi Lu, Fang Fang
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature cardiovascular research 3 (6) (2024)
Jacob Bergstedt, Joëlle A Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L Treur, Dirk J A Smit, Oleksandr Frei, Alexey A Shadrin, Joeri J Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas M Werge, Jens Hjerling Leffler, Thomas Damm Als, Anders Dupont Børglum, Cathryn M Lewis, Andrew M McIntosh, Unnur Anna Valdimarsdottir, Ole Andreas Andreassen, Patrick F Sullivan, Yi Lu, Fang Fang
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature cardiovascular research 3 (6) (2024)
Jacob Bergstedt, Joëlle A Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L Treur, Dirk J A Smit, Oleksandr Frei, Alexey A Shadrin, Joeri J Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas M Werge, Jens Hjerling Leffler, Thomas Damm Als, Anders Dupont Børglum, Cathryn M Lewis, Andrew M McIntosh, Unnur Anna Valdimarsdottir, Ole Andreas Andreassen, Patrick F Sullivan, Yi Lu, Fang Fang
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature cardiovascular research 3 (6) (2024)
Jacob Bergstedt, Joëlle A Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L Treur, Dirk J A Smit, Oleksandr Frei, Alexey A Shadrin, Joeri J Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas M Werge, Jens Hjerling Leffler, Thomas Damm Als, Anders Dupont Børglum, Cathryn M Lewis, Andrew M McIntosh, Unnur Anna Valdimarsdottir, Ole Andreas Andreassen, Patrick F Sullivan, Yi Lu, Fang Fang
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature cardiovascular research 3 (6) (2024)
Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N Lundström, Jian Zeng, Naomi R Wray, Yi Lu, Patrick F Sullivan, Jens Hjerling Leffler
Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity. medRxiv : the preprint server for health sciences (2024)
Jacob Bergstedt, Joëlle A Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L Treur, Dirk J A Smit, Oleksandr Frei, Alexey A Shadrin, Joeri J Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas M Werge, Jens Hjerling Leffler, Thomas Damm Als, Anders Dupont Børglum, Cathryn M Lewis, Andrew M McIntosh, Unnur Anna Valdimarsdottir, Ole Andreas Andreassen, Patrick F Sullivan, Yi Lu, Fang Fang
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature cardiovascular research 3 (6) (2024)
Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N Lundström, Jian Zeng, Naomi R Wray, Yi Lu, Patrick F Sullivan, Jens Hjerling Leffler
Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity. medRxiv : the preprint server for health sciences (2024)
Jacob Bergstedt, Joëlle A Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L Treur, Dirk J A Smit, Oleksandr Frei, Alexey A Shadrin, Joeri J Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas M Werge, Jens Hjerling Leffler, Thomas Damm Als, Anders Dupont Børglum, Cathryn M Lewis, Andrew M McIntosh, Unnur Anna Valdimarsdottir, Ole Andreas Andreassen, Patrick F Sullivan, Yi Lu, Fang Fang
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature cardiovascular research 3 (6) (2024)
Jacob Bergstedt, Joëlle A Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L Treur, Dirk J A Smit, Oleksandr Frei, Alexey A Shadrin, Joeri J Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas M Werge, Jens Hjerling Leffler, Thomas Damm Als, Anders Dupont Børglum, Cathryn M Lewis, Andrew M McIntosh, Unnur Anna Valdimarsdottir, Ole Andreas Andreassen, Patrick F Sullivan, Yi Lu, Fang Fang
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature cardiovascular research 3 (6) (2024)
Eliezyer Fermino de Oliveira, Pranjal Garg, Jens Hjerling Leffler, Renata Batista-Brito, Lucas Sjulson
Identifying patterns differing between high-dimensional datasets with generalized contrastive PCA. bioRxiv : the preprint server for biology (2024)
Eliezyer Fermino de Oliveira, Pranjal Garg, Jens Hjerling Leffler, Renata Batista-Brito, Lucas Sjulson
Identifying patterns differing between high-dimensional datasets with generalized contrastive PCA. bioRxiv : the preprint server for biology (2024)
Jacob Bergstedt, Joëlle A Pasman, Ziyan Ma, Arvid Harder, Shuyang Yao, Nadine Parker, Jorien L Treur, Dirk J A Smit, Oleksandr Frei, Alexey A Shadrin, Joeri J Meijsen, Qing Shen, Sara Hägg, Per Tornvall, Alfonso Buil, Thomas M Werge, Jens Hjerling Leffler, Thomas Damm Als, Anders Dupont Børglum, Cathryn M Lewis, Andrew M McIntosh, Unnur Anna Valdimarsdottir, Ole Andreas Andreassen, Patrick F Sullivan, Yi Lu, Fang Fang
Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature cardiovascular research 3 (6) (2024)
Amparo Roig Adam, José A Martínez-López, Sophie J F van der Spek, null null, Patrick F Sullivan, August B Smit, Matthijs Verhage, Jens Hjerling Leffler
Transcriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity. Biology direct 18 (1) (2023)
Amparo Roig Adam, José A Martínez-López, Sophie J F van der Spek, null null, Patrick F Sullivan, August B Smit, Matthijs Verhage, Jens Hjerling Leffler
Transcriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity. Biology direct 18 (1) (2023)
Amparo Roig Adam, José A Martínez-López, Sophie J F van der Spek, null null, Patrick F Sullivan, August B Smit, Matthijs Verhage, Jens Hjerling Leffler
Transcriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity. Biology direct 18 (1) (2023)
Rafael Yuste, Michael J Hawrylycz, Nadia Aalling Jessen, Argel Aguilar-Valles, Detlev Arendt, Ruben Armañanzas, Giorgio A Ascoli, Concha Bielza, Vahid Bokharaie, Tobias Borgtoft Bergmann, Irina Bystron, Marco Capogna, YoonJeung Chang, Ann M Clemens, Christiaan P J de Kock, Javier DeFelipe, Sandra Esmeralda Dos Santos, Keagan Dunville, Dirk Feldmeyer, Richárd Fiáth, Gordon James Fishell, Angelica Foggetti, Xuefan Gao, Parviz Ghaderi, Natalia A Goriounova, Onur Güntürkün, Kenta Hagihara, Vanessa Jane Hall, Moritz Helmstaedter, Suzana Herculano-Houzel, Markus M Hilscher, Hajime Hirase, Jens Hjerling Leffler, Rebecca D Hodge, Z Josh Huang, Rafiq Huda, Konstantin Khodosevich, Ole Kiehn, Henner Koch, Eric S Kuebler, Malte Kühnemund, Pedro Larrañaga, Boudewijn Lelieveldt, Emma Louise Louth, Jan H Lui, Huibert D Mansvelder, Oscar Marin, Julio C Martinez-Trujillo, Homeira Moradi Chameh, Alok Nath Mohapatra, Hermany Munguba, Maiken Nedergaard, Pavel Němec, Netanel Ofer, Ulrich Gottfried Pfisterer, Samuel Pontes, William Redmond, Jean Rossier, Joshua R Sanes, Richard H Scheuermann, Esther Serrano-Saiz, Jochen F Staiger, Peter Somogyi, Gabor Tamas, Andreas Savas Tolias, Maria Antonietta Tosches, Miguel Turrero García, Christian Wozny, Thomas V Wuttke, Yong Liu, Juan Yuan, Hongkui Zeng, Ed S Lein
A community-based transcriptomics classification and nomenclature of neocortical cell types. Nature neuroscience 23 (12) (2021)
Rafael Yuste, Michael J Hawrylycz, Nadia Aalling Jessen, Argel Aguilar-Valles, Detlev Arendt, Ruben Armañanzas, Giorgio A Ascoli, Concha Bielza, Vahid Bokharaie, Tobias Borgtoft Bergmann, Irina Bystron, Marco Capogna, Yoonjeung Chang, Ann M Clemens, Christiaan P J de Kock, Javier DeFelipe, Sandra Esmeralda Dos Santos, Keagan Dunville, Dirk Feldmeyer, Richárd Fiáth, Gordon James Fishell, Angelica Foggetti, Xuefan Gao, Parviz Ghaderi, Natalia A Goriounova, Onur Güntürkün, Kenta Hagihara, Vanessa Jane Hall, Moritz Helmstaedter, Suzana Herculano, Markus M Hilscher, Hajime Hirase, Jens Hjerling Leffler, Rebecca D Hodge, Z Josh Huang, Rafiq Huda, Konstantin Khodosevich, Ole Kiehn, Henner Koch, Eric S Kuebler, Malte Kühnemund, Pedro Larrañaga, Boudewijn Lelieveldt, Emma Louise Louth, Jan H Lui, Huibert D Mansvelder, Oscar Marin, Julio C Martinez-Trujillo, Homeira Moradi Chameh, Alok Nath Mohapatra, Maiken Nedergaard, Pavel Němec, Netanel Ofer, Ulrich Gottfried Pfisterer, Samuel Pontes, William Redmond, Jean Rossier, Joshua R Sanes, Richard H Scheuermann, Esther Serrano-Saiz, Jochen F Steiger, Peter Somogyi, Gabor Tamas, Andreas Savas Tolias, Maria Antonietta Tosches, Miguel Turrero Garcia, Hermany Munguba Vieira, Christian Wozny, Thomas V Wuttke, Yong Liu, Juan Yuan, Hongkui Zeng, Ed S Lein
Publisher Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types. Nature neuroscience (2020)
Hind Abdo, Laura Calvo-Enrique, Jose Martinez Lopez, Jianren Song, Ming-Dong Zhang, Dmitry Usoskin, Abdeljabbar El Manira, Igor Adameyko, Jens Hjerling Leffler, Patrik Ernfors
Specialized cutaneous Schwann cells initiate pain sensation. Science (New York, N.Y.) 365 (6454) (2020)
Enda M Byrne, Zhihong Zhu, Ting Qi, Nathan G Skene, Julien Bryois, Antonio F Pardinas, Eli A Stahl, Jordan W Smoller, Marcella D C Rietschel, null null, null null, Michael J Owen, James T R Walters, Michael C O'Donovan, John G McGrath, Jens Hjerling Leffler, Patrick F Sullivan, Michael E Goddard, Peter M Visscher, Jian Yang, Naomi R Wray
Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular psychiatry 26 (6) (2020)
Julien Bryois, Nathan G Skene, Thomas Folkmann Hansen, Lisette J A Kogelman, Hunna J Watson, Zijing Liu, null null, null null, null null, Leo Brueggeman, Gerome D Breen, Cynthia M Bulik, Ernest Arenas, Jens Hjerling Leffler, Patrick F Sullivan
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. Nature genetics 52 (5) (2020)
Philip R Jansen, Kyoko Watanabe, Sven Stringer, Nathan G Skene, Julien Bryois, Anke R Hammerschlag, Christiaan A de Leeuw, Jeroen S Benjamins, Ana B Muñoz-Manchado, Mats Nagel, Jeanne E Savage, Henning Tiemeier, Tonya White, null null, Joyce Y Tung, David A Hinds, Vladimir Vacic, Xin Wang, Patrick F Sullivan, Sophie van der Sluis, Tinca J C Polderman, August B Smit, Jens Hjerling Leffler, Eus J W Van Someren, Danielle Posthuma
Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Nature genetics 51 (3) (2019)
Xiaoyan Qian, Kenneth D Harris, Thomas Hauling, Dimitris Nicoloutsopoulos, Ana B Muñoz-Manchado, Nathan G Skene, Jens Hjerling Leffler, Mats Nilsson
Probabilistic cell typing enables fine mapping of closely related cell types in situ. Nature methods 17 (1) (2019)
Claire Bomkamp, Shreejoy J Tripathy, Carolina Bengtsson Gonzales, Jens Hjerling Leffler, Ann Marie Craig, Paul Pavlidis
Transcriptomic correlates of electrophysiological and morphological diversity within and across excitatory and inhibitory neuron classes. PLoS computational biology 15 (6) (2019)
Iris E Jansen, Jeanne E Savage, Kyoko Watanabe, Julien Bryois, Dylan M Williams, Stacy Steinberg, Julia Sealock, Ida K Karlsson, Sara Hägg, Lavinia Athanasiu, Nicola Voyle, Petroula Proitsi, Aree Witoelar, Sven Stringer, Dag Aarsland, Ina S Almdahl, Fred Andersen, Sverre Bergh, Francesco Bettella, Sigurbjorn Bjornsson, Anne Brækhus, Geir Bråthen, Christiaan A de Leeuw, Rahul S Desikan, Srdjan Djurovic, Logan Dumitrescu, Tormod Fladby, Timothy J Hohman, Palmi V Jonsson, Steven J Kiddle, Arvid Rongve, Ingvild Saltvedt, Sigrid B Sando, Geir Selbæk, Maryam Shoai, Nathan G Skene, Jon Snaedal, Eystein Stordal, Ingun D Ulstein, Yunpeng Wang, Linda R White, John Hardy, Jens Hjerling Leffler, Patrick F Sullivan, Wiesje M van der Flier, Richard James Butler Dobson, Lea K Davis, Hreinn Stefansson, Kári Stefánsson, Nancy L Pedersen, Stephan Ripke, Ole Andreas Andreassen, Danielle Posthuma
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. Nature genetics 51 (3) (2019)
Jonathan R I Coleman, Julien Bryois, Héléna A Gaspar, Philip R Jansen, Jeanne E Savage, Nathan Skene, Robert Plomin, Ana B Muñoz-Manchado, Sten Linnarsson, Greg Crawford, Jens Hjerling Leffler, Patrick F Sullivan, Danielle Posthuma, Gerome D Breen
Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. Molecular psychiatry 24 (2) (2018)
Jeanne E Savage, Philip R Jansen, Sven Stringer, Kyoko Watanabe, Julien Bryois, Christiaan A de Leeuw, Mats Nagel, Swapnil Awasthi, Peter B Barr, Jonathan R I Coleman, Katrina L Grasby, Anke R Hammerschlag, Jakob A Kaminski, Robert Karlsson, Eva Krapohl, Max Lam, Marianne Nygaard, Chandra A Reynolds, Joey W Trampush, Hannah Young, Delilah Zabaneh, Sara Hägg, Narelle K Hansell, Ida K Karlsson, Sten Linnarsson, Grant W Montgomery, Ana B Muñoz-Manchado, Erin B Quinlan, Gunter Schumann, Nathan G Skene, Bradley Todd Webb, Tonya White, Dan E Arking, Dimitrios Avramopoulos, Robert M Bilder, Panos Bitsios, Katherine E Burdick, Tyrone D Cannon, Ornit Chiba-Falek, Andrea Christoforou, Elizabeth T Cirulli, Eliza Congdon, Aiden Corvin, Gail Davies, Ian J Deary, Pamela DeRosse, Dwight Dickinson, Srdjan Djurovic, Gary Donohoe, Emily Drabant Conley, Johan G Eriksson, Thomas Espeseth, Nelson A Freimer, Stella Giakoumaki, Ina Giegling, Michael Gill, David C Glahn, Ahmad R Hariri, Alex Hatzimanolis, Matthew C Keller, Emma Knowles, Deborah Koltai, Bettina Konte, Jari M T Lahti, Stephanie Le Hellard, Todd Lencz, David C M Liewald, Edythe London, Astri Johansen Lundervold, Anil K Malhotra, Ingrid Melle, Derek Morris, Anna C Need, William Ollier, Aarno Palotie, Antony Payton, Neil Pendleton, Russell A Poldrack, Katri Räikkönen, Ivar Reinvang, Panagiotis Roussos, Dan Rujescu, Fred W Sabb, Matthew A Scult, Olav B Smeland, Nikolaos Smyrnis, John M Starr, Vidar M Steen, Nikos C Stefanis, Richard E Straub, Kjetil Sundet, Henning Tiemeier, Aristotle N Voineskos, Daniel R Weinberger, Elisabeth Widen, Jin Yu, Goncalo Abecasis, Ole Andreas Andreassen, Gerome D Breen, Lene Christiansen, Birgit Debrabant, Danielle M Dick, Andreas Heinz, Jens Hjerling Leffler, Mohammad Arfan Ikram, Kenneth S Kendler, Nicholas G Martin, Sarah E Medland, Nancy L Pedersen, Robert Plomin, Tinca J C Polderman, Stephan Ripke, Sophie van der Sluis, Patrick F Sullivan, Scott I Vrieze, Margaret J Wright, Danielle Posthuma
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature genetics 50 (7) (2018)
Nathan G Skene, Julien Bryois, Trygve E Bakken, Gerome D Breen, James J Crowley, Héléna A Gaspar, Paola Giusti-Rodriguez, Rebecca D Hodge, Jeremy A Miller, Ana B Muñoz-Manchado, Michael C O'Donovan, Michael J Owen, Antonio F Pardinas, Jesper Ryge, James T R Walters, Sten Linnarsson, Ed S Lein, null null, Patrick F Sullivan, Jens Hjerling Leffler
Genetic identification of brain cell types underlying schizophrenia. Nature genetics 50 (6) (2018)
Mats Nagel, Philip R Jansen, Sven Stringer, Kyoko Watanabe, Christiaan A de Leeuw, Julien Bryois, Jeanne E Savage, Anke R Hammerschlag, Nathan G Skene, Ana B Muñoz-Manchado, null null, Tonya White, Henning Tiemeier, Sten Linnarsson, Jens Hjerling Leffler, Tinca J C Polderman, Patrick F Sullivan, Sophie van der Sluis, Danielle Posthuma
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. Nature genetics 50 (7) (2018)
Changgeng Peng, Lili Li, Ming-Dong Zhang, Carolina Bengtsson Gonzales, Marc Parisien, Inna Belfer, Dmitry Usoskin, Hind Abdo, Alessandro Furlan, Martin Häring, François Lallemend, Tibor Harkany, Luda Diatchenko, Tomas Hökfelt, Jens Hjerling Leffler, Patrik Ernfors
miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. Science (New York, N.Y.) 356 (6343) (2017)
Jean-Francois Poulin, Bosiljka Tasic, Jens Hjerling Leffler, Jeffrey M Trimarchi, Rajeshwar Awatramani
Disentangling neural cell diversity using single-cell transcriptomics. Nature neuroscience 19 (9) (2017)
Dmitry Usoskin, Alessandro Furlan, Saiful Islam, Hind Abdo, Peter Lönnerberg, Daohua Lou, Jens Hjerling Leffler, Jesper Haeggström, Olga Kharchenko, Peter V Kharchenko, Sten Linnarsson, Patrik Ernfors
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing. Nature neuroscience 18 (1) (2014)