John Loughlin

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 13

Top Venues

Arthritis & rheumatology (Hoboken, N.J.)

Arthritis research & therapy

PloS one

Human molecular genetics

Newcastle University

University of Leeds (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Newcastle University Jan 01 2008

United Kingdom

Professor :: Medical Faculty

University of Oxford May 01 2002 - Dec 31 2007

United Kingdom

University Lecturer (tenured post) :: Nuffield Department of Orthopaedic Surgery

University of Oxford May 01 1997 - May 01 2002

United Kingdom

Research Fellow and PI :: Nuffield Department of Clinical Laboratory Science

University of Oxford Jan 02 1995 - May 01 1997

United Kingdom

Postdoctoral Scientist :: Wellcome Trust Centre for Human Genetics

University of Oxford Dec 01 1990 - Jan 01 1995

United Kingdom

Postdoctoral Scientist :: Institute of Molecular Medicine

Education History

University of Leeds Oct 01 1987 - Nov 15 1990

United Kingdom

PHD

Liverpool Polytechnic Oct 01 1983 - Jun 30 1987

United Kingdom

BSC

Publications

Jack B Roberts, Olivia L G Boldvig, Guillaume Aubourg, S Tanishq Kanchenapally, David J Deehan, Sarah J Rice, John Loughlin
Specific isoforms of the ubiquitin ligase gene WWP2 are targets of osteoarthritis genetic risk via a differentially methylated DNA sequence. Arthritis research & therapy 26 (1) (2024)
Jack B Roberts, Olivia L G Boldvig, Guillaume Aubourg, S Tanishq Kanchenapally, David J Deehan, Sarah J Rice, John Loughlin
Specific isoforms of the ubiquitin ligase gene WWP2 are targets of osteoarthritis genetic risk via a differentially methylated DNA sequence. Arthritis research & therapy 26 (1) (2024)
Jack B Roberts, Olivia L G Boldvig, Guillaume Aubourg, S Tanishq Kanchenapally, David J Deehan, Sarah J Rice, John Loughlin
Specific isoforms of the ubiquitin ligase gene WWP2 are targets of osteoarthritis genetic risk via a differentially methylated DNA sequence. Arthritis research & therapy 26 (1) (2024)
Yulia S Kehayova, Jeremy Mark Wilkinson, Sarah J Rice, John Loughlin
Independent osteoarthritis risk-conferring alleles mediate the same epigenetic and transcriptional effect on a shared target gene, COLGALT2. Arthritis & rheumatology (Hoboken, N.J.) (2022)
Sarah J Rice, Abby Brumwell, Julia Falk, Yulia S Kehayova, John Casement, Eleanor Parker, Ines M J Hofer, Colin Shepherd, John Loughlin
Genetic risk of osteoarthritis operates during human skeletogenesis. Human molecular genetics (2022)
Yulia S Kehayova, Jeremy Mark Wilkinson, Sarah J Rice, John Loughlin
Independent osteoarthritis risk-conferring alleles mediate the same epigenetic and transcriptional effect on a shared target gene, COLGALT2. Arthritis & rheumatology (Hoboken, N.J.) (2022)
Abby Brumwell, Guillaume Aubourg, Juhel Hussain, Eleanor Parker, David J Deehan, Sarah J Rice, John Loughlin
Identification of TMEM129, encoding a ubiquitin-protein ligase, as an effector gene of osteoarthritis genetic risk. Arthritis research & therapy 24 (1) (2022)
Yulia S Kehayova, Jeremy Mark Wilkinson, Sarah J Rice, John Loughlin
Independent osteoarthritis risk-conferring alleles mediate the same epigenetic and transcriptional effect on a shared target gene, COLGALT2. Arthritis & rheumatology (Hoboken, N.J.) (2022)
Sarah J Rice, Jack B Roberts, Maria Tselepi, Abby Brumwell, Julia Falk, Charlotte Steven, John Loughlin
Genetic and Epigenetic Fine-Tuning of TGFB1 Expression Within the Human Osteoarthritic Joint. Arthritis & rheumatology (Hoboken, N.J.) 73 (10) (2021)
Yulia S Kehayova, Emily Watson, Jeremy Mark Wilkinson, John Loughlin, Sarah J Rice
Genetic and Epigenetic Interplay Within a COLGALT2 Enhancer Associated With Osteoarthritis. Arthritis & rheumatology (Hoboken, N.J.) 73 (10) (2021)
Sarah J Rice, Frank Beier, David A Young, John Loughlin
Interplay between genetics and epigenetics in osteoarthritis. Nature reviews. Rheumatology 16 (5) (2020)
Madhushika Ratnayake, Maria Tselepi, Robert Bloxham, Frank Plöger, Louise N Reynard, John Loughlin
A consistent and potentially exploitable response during chondrogenesis of mesenchymal stem cells from osteoarthritis patients to the protein encoded by the susceptibility gene GDF5. PloS one 12 (5) (2017)
Louise N Reynard, Madhushika Ratnayake, Mauro Santibanez-Koref, John Loughlin
Functional Characterization of the Osteoarthritis Susceptibility Mapping to CHST11-A Bioinformatics and Molecular Study. PloS one 11 (7) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

John Loughlin