Jonathan Clayden

Scopus author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 57

Top Topics

Molecular Dynamics Simulations

Electron Transfer

Capillary Electrophoresis

Top Venues

Angewandte Chemie (International ed. in English)

Chemical science

Organic letters

Chemistry (Weinheim an der Bergstrasse, Germany)

This page only lists publications with an associated author ORCID identifier.

Publications

Rajendra K Mallick, Matej Žabka, Jonathan Clayden
Benzo-fused Nitrogen Heterocycles by Asymmetric Ring Expansion and Stereochemically Retentive Re-contraction of Cyclic Ureas. Angewandte Chemie (International ed. in English) 63 (12) (2024)
Mehul H Jesani, Maria Schwarz, Shiwhu Kim, Finlay L Evans, Alexander White, Alex Browning, Roman Abrams, Jonathan Clayden
Selective Defluorination of Trifluoromethyl Substituents by Conformationally Induced Remote Substitution. Angewandte Chemie (International ed. in English) 63 (24) (2024)
Branca C van Veen, Jonathan Clayden
Intramolecular Nucleophilic Vinylic Substitution (S N V) by Carbon Nucleophiles: Conformationally Directed Formation of Dienes from N,N'-Diallyl Ureas. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Rajendra K Mallick, Matej Žabka, Jonathan Clayden
Benzo-fused Nitrogen Heterocycles by Asymmetric Ring Expansion and Stereochemically Retentive Re-contraction of Cyclic Ureas. Angewandte Chemie (International ed. in English) (2024)
Mehul H Jesani, Maria Schwarz, Shiwhu Kim, Finlay L Evans, Alexander White, Alex Browning, Roman Abrams, Jonathan Clayden
Selective Defluorination of Trifluoromethyl Substituents by Conformationally Induced Remote Substitution. Angewandte Chemie (International ed. in English) (2024)
Jean-Paul Heeb, Jonathan Clayden, Martin D Smith, Roly J Armstrong
Interrogating the configurational stability of atropisomers. Nature protocols (2023)
Matej Žabka, Jonathan Clayden
Conformational preference in difluoroacetamide oligomers: probing the potential for foldamers with C-H⋯O hydrogen bonds. Organic & biomolecular chemistry (2023)
David P Tilly, Jean-Paul Heeb, Simon J Webb, Jonathan Clayden
Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer. Nature communications 14 (1) (2023)
Ellie Stammers, Chris D Parsons, Jonathan Clayden, Alastair J J Lennox
Electrochemical synthesis of biaryls by reductive extrusion from N,N'-diarylureas. Nature communications 14 (1) (2023)
David T J Morris, Steven M Wales, Javier Echavarren, Matej Žabka, Giulia Marsico, John W Ward, Natalie E Pridmore, Jonathan Clayden
Dynamic and Persistent Cyclochirality in Hydrogen-Bonded Derivatives of Medium-Ring Triamines. Journal of the American Chemical Society (2023)
David T J Morris, Jonathan Clayden
Screw sense and screw sensibility: communicating information by conformational switching in helical oligomers. Chemical Society reviews (2023)
Rakesh K Saunthwal, Maria Schwarz, Rajendra K Mallick, William Terry-Wright, Jonathan Clayden
Enantioselective Intramolecular α-Arylation of Benzylamine Derivatives: Synthesis of a Precursor to Levocetirizine. Angewandte Chemie (International ed. in English) 62 (14) (2023)
Rakesh K Saunthwal, Maria Schwarz, Rajendra K Mallick, William Terry-Wright, Jonathan Clayden
Enantioselective Intramolecular α-Arylation of Benzylamine Derivatives: Synthesis of a Precursor to Levocetirizine. Angewandte Chemie (International ed. in English) (2023)
David P Tilly, Jean-Paul Heeb, Simon J Webb, Jonathan Clayden
Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer. Nature communications 14 (1) (2023)
David P Tilly, Jean-Paul Heeb, Simon J Webb, Jonathan Clayden
Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer. Nature communications 14 (1) (2023)
Prasun Kumar, Neil G Paterson, Jonathan Clayden, Derek N Woolfson
De novo design of discrete, stable 3 10 -helix peptide assemblies. Nature 607 (7918) (2022)
Rakesh K Saunthwal, James Mortimer, Andrew J Orr-Ewing, Jonathan Clayden
Enantioselective one-carbon expansion of aromatic rings by simultaneous formation and chromoselective irradiation of a transient coloured enolate. Chemical science 13 (7) (2022)
David P Tilly, Matej Žabka, Inigo Vitorica-Yrezabal, Hazel A Sparkes, Natalie Pridmore, Jonathan Clayden
Supramolecular interactions between ethylene-bridged oligoureas: nanorings and chains formed by cooperative positive allostery. Chemical science 13 (44) (2022)
Matthew M Wootten, Sofja Tshepelevitsh, Ivo Leito, Jonathan Clayden
A Chemically Fuelled Molecular Automaton Displaying Programmed Migration of Zn 2+ Between Alternative Binding Sites. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (59) (2022)
Steven M Wales, David T J Morris, Jonathan Clayden
Reversible Capture and Release of a Ligand Mediated by a Long-Range Relayed Polarity Switch in a Urea Oligomer. Journal of the American Chemical Society 144 (7) (2022)
Olivia F B Watts, Jordan Berreur, Beatrice S L Collins, Jonathan Clayden
Biocatalytic Enantioselective Synthesis of Atropisomers. Accounts of chemical research 55 (23) (2022)
Steven M Wales, Rakesh K Saunthwal, Jonathan Clayden
C(sp 3 )-Arylation by Conformationally Accelerated Intramolecular Nucleophilic Aromatic Substitution (S N Ar). Accounts of chemical research 55 (12) (2022)
Matthew M Wootten, Bryden A F Le Bailly, Sofja Tshepelevitsh, Ivo Leito, Jonathan Clayden
Inducing a pH-dependent conformational response by competitive binding to Zn 2+ of a series of chiral ligands of disparate basicity. Chemical science 13 (8) (2022)
Daniel J Leonard, Francis Zieleniewski, Isabelle Wellhöfer, Emily G Baker, John W Ward, Derek N Woolfson, Jonathan Clayden
Scalable synthesis and coupling of quaternary α-arylated amino acids: α-aryl substituents are tolerated in α-helical peptides. Chemical science 12 (27) (2021)
Roman Abrams, Mehul H Jesani, Alex Browning, Jonathan Clayden
Triarylmethanes and their Medium-Ring Analogues by Unactivated Truce-Smiles Rearrangement of Benzanilides. Angewandte Chemie (International ed. in English) 60 (20) (2021)
Matteo Pollastrini, Giulia Marafon, Jonathan Clayden, Alessandro Moretto
Light-mediated control of activity in a photosensitive foldamer that mimics an esterase. Chemical communications (Cambridge, England) 57 (18) (2021)
Louise Eagling, Daniel J Leonard, Maria Schwarz, Iñaki Urruzuno, Grace Boden, J Steven Wailes, John W Ward, Jonathan Clayden
'Reverse biomimetic' synthesis of l-arogenate and its stabilized analogues from l-tyrosine. Chemical science 12 (34) (2021)
Branca C van Veen, Steven M Wales, Jonathan Clayden
N-Methyl Allylic Amines from Allylic Alcohols by Mitsunobu Substitution Using N-Boc Ethyl Oxamate. The Journal of organic chemistry 86 (12) (2021)
Anna D Peters, Stefan Borsley, Flavio Della Sala, Dominic F Cairns-Gibson, Marios Leonidou, Jonathan Clayden, George F S Whitehead, Iñigo J Vitorica-Yrezabal, Eriko Takano, John Burthem, Scott L Cockroft, Simon J Webb
Switchable foldamer ion channels with antibacterial activity. Chemical science 11 (27) (2020)
Makenzie J Millward, Emily Ellis, John W Ward, Jonathan Clayden
Hydantoin-bridged medium ring scaffolds by migratory insertion of urea-tethered nitrile anions into aromatic C-N bonds. Chemical science 12 (6) (2020)
Romain Costil, Alistair J Sterling, Fernanda Duarte, Jonathan Clayden
Atropisomerism in Diarylamines: Structural Requirements and Mechanisms of Conformational Interconversion. Angewandte Chemie (International ed. in English) 59 (42) (2020)
Roman Abrams, Jonathan Clayden
Photocatalytic Difunctionalization of Vinyl Ureas by Radical Addition Polar Truce-Smiles Rearrangement Cascades. Angewandte Chemie (International ed. in English) 59 (28) (2020)
Mostafa Mahmoud Amer, Hossay Abas, Daniel J Leonard, John W Ward, Jonathan Clayden
Amino Acid-Derived trans- N-Chloroformylimidazolidinones: Scalable, Stereoselective Synthesis, Structure, and Utility. The Journal of organic chemistry 84 (11) (2019)
Natasha Eccles, Bryden A F Le Bailly, Flavio Della Sala, Iñigo J Vitórica-Yrezábal, Jonathan Clayden, Simon J Webb
Remote conformational responses to enantiomeric excess in carboxylate-binding dynamic foldamers. Chemical communications (Cambridge, England) 55 (63) (2019)
Mostafa M Amer, Olatz Olaizola, Jennifer Carter, Hossay Abas, Jonathan Clayden
An Aliphatic Bischler-Napieralski Reaction: Dihydropyridones by Cyclocarbonylation of 3-Allylimidazolidin-4-ones. Organic letters 22 (1) (2019)
Hossay Abas, Mostafa M Amer, Olatz Olaizola, Jonathan Clayden
N-Chloroformylimidazolidinone Enolates as 1,3-Dipolar Reagents for the Stereoselective Synthesis of 3,4-Dihydroisoquinolones. Organic letters 21 (6) (2019)
Hossay Abas, Josep Mas-Roselló, Mostafa Mahmoud Amer, Derek J Durand, Robin R Groleau, Natalie Fey, Jonathan Clayden
Asymmetric and Geometry-Selective α-Alkenylation of α-Amino Acids. Angewandte Chemie (International ed. in English) 58 (8) (2019)
Rakesh K Saunthwal, Matthew T Cornall, Roman Abrams, John W Ward, Jonathan Clayden
Connective synthesis of 5,5-disubstituted hydantoins by tandem α-amination and α-arylation of silyl ketene acetals. Chemical science 10 (11) (2019)
Marta De Zotti, Jonathan Clayden
Extended Diethylglycine Homopeptides Formed by Desulfurization of Their Tetrahydrothiopyran Analogues. Organic letters 21 (7) (2019)
Jessica E Hill, Quentin Lefebvre, Laura A Fraser, Jonathan Clayden
Polycyclic Indoline Derivatives by Dearomatizing Anionic Cyclization of Indole and Tryptamine-Derived Ureas. Organic letters 20 (18) (2018)
Catherine Adam, Anna D Peters, M Giovanna Lizio, George F S Whitehead, Vincent Diemer, James A Cooper, Scott L Cockroft, Jonathan Clayden, Simon J Webb
The Role of Terminal Functionality in the Membrane and Antibacterial Activity of Peptaibol-Mimetic Aib Foldamers. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (9) (2018)
Roman Abrams, Quentin Lefebvre, Jonathan Clayden
Transition Metal Free Cycloamination of Prenyl Carbamates and Ureas Promoted by Aryldiazonium Salts. Angewandte Chemie (International ed. in English) 57 (41) (2018)
Francis G A Lister, Natasha Eccles, Sarah J Pike, Robert A Brown, George F S Whitehead, James Raftery, Simon J Webb, Jonathan Clayden
Bis-pyrene probes of foldamer conformation in solution and in phospholipid bilayers. Chemical science 9 (33) (2018)
Romina Wechsel, Matej Žabka, John W Ward, Jonathan Clayden
Competing Hydrogen-Bond Polarities in a Dynamic Oligourea Foldamer: A Molecular Spring Torsion Balance. Journal of the American Chemical Society 140 (10) (2018)
Mostafa M Amer, Ana C Carrasco, Daniel J Leonard, John W Ward, Jonathan Clayden
Substituted Dihydroisoquinolinones by Iodide-Promoted Cyclocarbonylation of Aromatic α-Amino Acids. Organic letters 20 (24) (2018)
Jessica E Hill, Johnathan V Matlock, Quentin Lefebvre, Katie G Cooper, Jonathan Clayden
Consecutive Ring Expansion and Contraction for the Synthesis of 1-Aryl Tetrahydroisoquinolines and Tetrahydrobenzazepines from Readily Available Heterocyclic Precursors. Angewandte Chemie (International ed. in English) 57 (20) (2018)
Wojciech Zawodny, Sarah L Montgomery, James R Marshall, James D Finnigan, Nicholas J Turner, Jonathan Clayden
Chemoenzymatic Synthesis of Substituted Azepanes by Sequential Biocatalytic Reduction and Organolithium-Mediated Rearrangement. Journal of the American Chemical Society 140 (51) (2018)
Maria Giovanna Lizio, Valery Andrushchenko, Sarah J Pike, Anna D Peters, George F S Whitehead, Iñigo J Vitorica-Yrezabal, Shaun T Mutter, Jonathan Clayden, Petr Bouř, Ewan W Blanch, Simon J Webb
Optically Active Vibrational Spectroscopy of α-Aminoisobutyric Acid Foldamers in Organic Solvents and Phospholipid Bilayers. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (37) (2018)
Romain Costil, Quentin Lefebvre, Jonathan Clayden
Medium-Sized-Ring Analogues of Dibenzodiazepines by a Conformationally Induced Smiles Ring Expansion. Angewandte Chemie (International ed. in English) 56 (46) (2017)
Romain Costil, Harvey J A Dale, Natalie Fey, George Whitcombe, Johnathan V Matlock, Jonathan Clayden
Heavily Substituted Atropisomeric Diarylamines by Unactivated Smiles Rearrangement of N-Aryl Anthranilamides. Angewandte Chemie (International ed. in English) 56 (41) (2017)
Michael Tomsett, Irene Maffucci, Bryden A F Le Bailly, Liam Byrne, Stefan M Bijvoets, M Giovanna Lizio, James Raftery, Craig P Butts, Simon J Webb, Alessandro Contini, Jonathan Clayden
A tendril perversion in a helical oligomer: trapping and characterizing a mobile screw-sense reversal. Chemical science 8 (4) (2017)
Julien Maury, Wojciech Zawodny, Jonathan Clayden
Stereospecific Intramolecular Arylation of 2- and 3-Pyridyl Substituted Alkylamines via Configurationally Stable α-Pyridyl Organolithiums. Organic letters 19 (3) (2017)
Josep Mas-Roselló, Shuji Hachisu, Jonathan Clayden
Geometry-Retentive C-Alkenylation of Lithiated α-Aminonitriles: Quaternary α-Alkenyl Amino Acids and Hydantoins. Angewandte Chemie (International ed. in English) 56 (36) (2017)
Bryden A F Le Bailly, Liam Byrne, Jonathan Clayden
Refoldable Foldamers: Global Conformational Switching by Deletion or Insertion of a Single Hydrogen Bond. Angewandte Chemie (International ed. in English) 55 (6) (2016)
Samantha Staniland, Ralph W Adams, Joseph J W McDouall, Irene Maffucci, Alessandro Contini, Damian M Grainger, Nicholas J Turner, Jonathan Clayden
Biocatalytic Dynamic Kinetic Resolution for the Synthesis of Atropisomeric Biaryl N-Oxide Lewis Base Catalysts. Angewandte Chemie (International ed. in English) 55 (36) (2016)
Romina Wechsel, James Raftery, Dominique Cavagnat, Gilles Guichard, Jonathan Clayden
The meso Helix: Symmetry and Symmetry-Breaking in Dynamic Oligourea Foldamers with Reversible Hydrogen-Bond Polarity. Angewandte Chemie (International ed. in English) 55 (33) (2016)
Jessica E Hall, Johnathan V Matlock, John W Ward, Katharine V Gray, Jonathan Clayden
Medium-Ring Nitrogen Heterocycles through Migratory Ring Expansion of Metalated Ureas. Angewandte Chemie (International ed. in English) 55 (37) (2016)