Jonathan D Powell

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 13

Top Topics

Acute Myeloid Leukemia

Immune Response

Dendritic Cells

Top Venues

Cancer immunology research

Nature reviews. Cancer

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Monali Praharaj, Fan Shen, Alex J Lee, Liang Zhao, Thomas R Nirschl, Debebe Theodros, Alok K Singh, Xiaoxu Wang, Kenneth M Adusei, Kara A Lombardo, Raekwon A Williams, Laura A Sena, Elizabeth A Thompson, Ada J Tam, Srinivasan Yegnasubramanian, Edward J Pearce, Robert D Leone, Jesse Alt, Rana Rais, Barbara S Slusher, Drew M Pardoll, Jonathan D Powell, Jelani C Zarif
Metabolic Reprogramming of Tumor-Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancers. Cancer immunology research 12 (7) (2024)
Monali Praharaj, Fan Shen, Alex J Lee, Liang Zhao, Thomas R Nirschl, Debebe Theodros, Alok K Singh, Xiaoxu Wang, Kenneth M Adusei, Kara A Lombardo, Raekwon A Williams, Laura A Sena, Elizabeth A Thompson, Ada J Tam, Srinivasan Yegnasubramanian, Edward J Pearce, Robert D Leone, Jesse Alt, Rana Rais, Barbara S Slusher, Drew M Pardoll, Jonathan D Powell, Jelani C Zarif
Metabolic Reprogramming of Tumor-Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancers. Cancer immunology research 12 (7) (2024)
Monali Praharaj, Fan Shen, Alex J Lee, Liang Zhao, Thomas R Nirschl, Debebe Theodros, Alok K Singh, Xiaoxu Wang, Kenneth M Adusei, Kara A Lombardo, Raekwon A Williams, Laura A Sena, Elizabeth A Thompson, Ada J Tam, Srinivasan Yegnasubramanian, Edward J Pearce, Robert D Leone, Jesse Alt, Rana Rais, Barbara S Slusher, Drew M Pardoll, Jonathan D Powell, Jelani C Zarif
Metabolic reprogramming of tumor-associated macrophages using glutamine antagonist JHU083 drives tumor immunity in myeloid-rich prostate and bladder cancer tumors. Cancer immunology research (2024)
Monali Praharaj, Fan Shen, Alex J Lee, Liang Zhao, Thomas R Nirschl, Debebe Theodros, Alok K Singh, Xiaoxu Wang, Kenneth M Adusei, Kara A Lombardo, Raekwon A Williams, Laura A Sena, Elizabeth A Thompson, Ada J Tam, Srinivasan Yegnasubramanian, Edward J Pearce, Robert D Leone, Jesse Alt, Rana Rais, Barbara S Slusher, Drew M Pardoll, Jonathan D Powell, Jelani C Zarif
Metabolic Reprogramming of Tumor-Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancers. Cancer immunology research 12 (7) (2024)
Wei Xu, Chirag H Patel, Jesse Alt, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Richard L Blosser, Ada J Tam, Jonathan D Powell
GOT1 constrains T H 17 cell differentiation, while promoting iT reg cell differentiation. Nature 614 (7946) (2023)
Wei Xu, Chirag H Patel, Jesse Alt, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Richard L Blosser, Ada J Tam, Jonathan D Powell
GOT1 constrains T H 17 cell differentiation, while promoting iT reg cell differentiation. Nature 614 (7946) (2023)
Wei Xu, Chirag H Patel, Jesse Alt, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Richard L Blosser, Ada J Tam, Jonathan D Powell
GOT1 constrains T H 17 cell differentiation, while promoting iT reg cell differentiation. Nature 614 (7946) (2023)
Rana Rais, Kathryn M Lemberg, Lukáš Tenora, Matthew L Arwood, Arindom Pal, Jesse Alt, Ying Wu, Jenny Lam, Joanna Marie H Aguilar, Liang Zhao, Diane E Peters, Carolyn Tallon, Rajeev Pandey, Ajit G Thomas, Ranjeet P Dash, Tanguy Y Seiwert, Pavel Majer, Robert D Leone, Jonathan D Powell, Barbara S Slusher
Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug. Science advances 8 (46) (2022)
Michael D Claiborne, Srona Sengupta, Liang Zhao, Matthew L Arwood, Im-Meng Sun, Jiayu Wen, Elizabeth A Thompson, Marisa Mitchell-Flack, Marikki Laiho, Jonathan D Powell
Persistent CAD activity in memory CD8 + T cells supports rRNA synthesis and ribosomal biogenesis required at rechallenge. Science immunology 7 (71) (2022)
Alvaro A Ordonez, Cynthia Korin Bullen, Andres F Villabona-Rueda, Elizabeth A Thompson, Mitchell L Turner, Stephanie L Davis, Oliver Komm, Jonathan D Powell, Franco R D'Alessio, Robert H Yolken, Sanjay K Jain, Lorraine Jones-Brando
Sulforaphane exhibits in vitro and in vivo antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses. bioRxiv : the preprint server for biology (2021)
Robert D Leone, Jonathan D Powell
Metabolism of immune cells in cancer. Nature reviews. Cancer 20 (9) (2020)
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen, Ada Tam, Richard L Blosser, Eva Prchalova, Jesse Alt, Rana Rais, Barbara S Slusher, Jonathan D Powell
Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science (New York, N.Y.) 366 (6468) (2019)
Chirag H Patel, Robert D Leone, Maureen R Horton, Jonathan D Powell
Targeting metabolism to regulate immune responses in autoimmunity and cancer. Nature reviews. Drug discovery 18 (9) (2019)