Junwei Wang

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 9

Top Topics

Acute Myeloid Leukemia

Molecular Dynamics Simulations

Tyrosine Kinase

Highly Efficient

Top Venues

Journal of medicinal chemistry

Organic letters

The Journal of organic chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Junwei Wang, Quanjin Rong, Lei Ye, Bingqian Fang, Yifan Zhao, Yu Sun, Haikun Zhou, Dan Wang, Jinting He, Zhenzhen Cui, Qijian Zhang, Di Kang, Lihong Hu
Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors. Journal of medicinal chemistry (2024)
Qi Lv, Hongqiong Yang, Dan Wang, Haikun Zhou, Juan Wang, Yishu Zhang, Dapeng Wu, Ying Xie, Yingshan Lv, Lihong Hu, Junwei Wang
Discovery of a Novel CSF-1R Inhibitor with Highly Improved Pharmacokinetic Profiles and Superior Efficacy in Colorectal Cancer Immunotherapy. Journal of medicinal chemistry (2024)
Junwei Wang, Quanjin Rong, Lei Ye, Bingqian Fang, Yifan Zhao, Yu Sun, Haikun Zhou, Dan Wang, Jinting He, Zhenzhen Cui, Qijian Zhang, Di Kang, Lihong Hu
Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors. Journal of medicinal chemistry 67 (9) (2024)
Qi Lv, Hongqiong Yang, Dan Wang, Haikun Zhou, Juan Wang, Yishu Zhang, Dapeng Wu, Ying Xie, Yingshan Lv, Lihong Hu, Junwei Wang
Discovery of a Novel CSF-1R Inhibitor with Highly Improved Pharmacokinetic Profiles and Superior Efficacy in Colorectal Cancer Immunotherapy. Journal of medicinal chemistry 67 (8) (2024)
Junwei Wang, Xiang Pan, Yi Song, Jian Liu, Fei Ma, Ping Wang, Yan Liu, Lin Zhao, Di Kang, Lihong Hu
Discovery of a Potent and Selective FLT3 Inhibitor (Z)-N-(5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-4-methyl-1H-pyrrol-3-yl)-3-(pyrrolidin-1-yl)propanamide with Improved Drug-like Properties and Superior Efficacy in FLT3-ITD-Positive Acute Myeloid Leukemia. Journal of medicinal chemistry 64 (8) (2021)
Qi Lv, Xiang Pan, Dan Wang, Quanjin Rong, Ben Ma, Xiaolong Xie, Yi-Nan Zhang, Junwei Wang, Lihong Hu
Discovery of (Z)-1-(3-((1H-Pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)-3-(isoxazol-3-yl)urea Derivatives as Novel and Orally Highly Effective CSF-1R Inhibitors for Potential Colorectal Cancer Immunotherapy. Journal of medicinal chemistry 64 (23) (2021)
Junwei Wang, Xiang Pan, Quanjin Rong, Lei Zhao, Lin Zhao, Weichen Dai, Kun Zhao, Lihong Hu
One-pot synthesis of indoles and quinolinones from ortho -tosylaminophenyl-substituted para -quinone methides. RSC advances 10 (55) (2020)
Junwei Wang, Lei Zhao, Quanjin Rong, Cheng Lv, Yu Lu, Xiang Pan, Lin Zhao, Lihong Hu
Asymmetric Synthesis of 3,3'-Tetrahydrofuryl Spirooxindoles via Palladium-Catalyzed [3+2] Cycloadditions of Methyleneindolinones with Vinylethylene Carbonates. Organic letters 22 (15) (2020)
Junwei Wang, Quanjin Rong, Lei Zhao, Xiang Pan, Lin Zhao, Kun Zhao, Lihong Hu
Synthesis of 1,4-Dihydroquinolines and 4H-Chromenes via Organocatalytic Domino Aza/Oxa-Michael/1,6-Addition Reactions of para-Quinone Methides and Ynals. The Journal of organic chemistry 85 (17) (2020)